Blood immune cells from people with HIV on antiviral regimens that contain tenofovir alafenamide (TAF) and tenofovir disoproxil fumarate (TDF) have differential metabolic signatures

Authors: Ritou, Eleni, Satta, Sandro, Petcherski, Anton, Daskou, Maria, Sharma, Madhav, Vasilopoulos, Hariclea, Murakami, Eisuke, Shirihai, Orian S., Kelesidis, Theodoros

Source: In Metabolism April 2023 141

Development of targeted nanoparticles loaded with antiviral drugs for SARS-CoV-2 inhibition

Authors: Sanna, Vanna, Satta, Sandro, Hsiai, Tzung, Sechi, Mario

Source: In European Journal of Medicinal Chemistry 5 March 2022 231

Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection

Authors: Kaneko, Naoki, Satta, Sandro, Komuro, Yutaro, Muthukrishnan, Sree Deepthi, Kakarla, Visesha, Guo, Lea, An, Jennifer, Elahi, Fanny, Kornblum, Harley I., Liebeskind, David S., Hsiai, Tzung, Hinman, Jason D.

Source: Stroke. 52(1):260-270

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Mitoquinone mesylate attenuates brain inflammation in humanized mouse model of chronic HIV infection

Authors: Satta, Sandro, Hugo, Cristelle, Sharma, Madhav, Rezek, Valerie, Kossyvakis, Athanassios, Roy, Shubhendu Sen, Kitchen, Scott, Kelesidis, Theodoros

Source: AIDS. 36(11):1609-1611

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Discovery of novel functionalized 1,2,4-triazoles as PARP-1 inhibitors in breast cancer: Design, synthesis and antitumor activity evaluation

Authors: Boraei, Ahmed T.A., Singh, Pankaj K., Sechi, Mario, Satta, Sandro

Source: In European Journal of Medicinal Chemistry 15 November 2019 182

Rapid Detection and Inhibition of SARS‐CoV‐2‐Spike Mutation‐Mediated Microthrombosis

Authors: Satta, Sandro, Lai, Angela, Cavallero, Susana, Williamson, Cayden, Chen, Justin, Blázquez‐Medela, Ana M., Roustaei, Mehrdad, Dillon, Barbara J., Ashammakhi, Nureddin, Carlo, Dino Di, Li, Zhaoping, Sun, Ren, Hsiai, Tzung K.

Source: Advanced science. 8(23)

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α-Glucosidase inhibition by green, white and oolong teas: in vitro activity and computational studies.

Authors: Esposito, Fabio, Pala, Nicolino, Carcelli, Mauro, Boateng, Samuel T., D'Aquila, Paolo S., Mariani, Alberto, Satta, Sandro, Chamcheu, Jean Christopher, Sechi, Mario, Sanna, Vanna

Source: Journal of Enzyme Inhibition & Medicinal Chemistry; Dec2023, Vol. 38 Issue 1, p1-10, 10p

Subject Terms: GREEN tea, TEA, CATECHIN, ACARBOSE

Company/Entity: UNITED States. Food & Drug Administration

Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

Authors: Sindi, Hebah A., Russomanno, Giusy, Satta, Sandro, Abdul-Salam, Vahitha B., Jo, Kyeong Beom, Qazi-Chaudhry, Basma, Ainscough, Alexander J., Szulcek, Robert, Jan Bogaard, Harm, Morgan, Claire C., Pullamsetti, Soni S., Alzaydi, Mai M., Rhodes, Christopher J., Piva, Roberto, Eichstaedt, Christina A., Grünig, Ekkehard, Wilkins, Martin R., Wojciak-Stothard, Beata

Source: Nature communications. 11(1)

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Author Correction: Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

Authors: Sindi, Hebah A., Russomanno, Giusy, Satta, Sandro, Abdul-Salam, Vahitha B., Jo, Kyeong Beom, Qazi-Chaudhry, Basma, Ainscough, Alexander J., Szulcek, Robert, Bogaard, Harm Jan, Morgan, Claire C., Pullamsetti, Soni S., Alzaydi, Mai M., Rhodes, Christopher J., Piva, Roberto, Eichstaedt, Christina A., Grünig, Ekkehard, Wilkins, Martin R., Wojciak-Stothard, Beata

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174569073.0x000001&indx=1&recIds=ETOCvdc_100174569073.0x000001

Mitoquinone Mesylate and Mitochondrial DNA in End Organs in Humanized Mouse Model of Chronic Treated Human Immunodeficiency Virus Infection.

Authors: Song, Sihyeong¹ (AUTHOR), Satta, Sandro¹ (AUTHOR), Sharma, Madhav B¹ (AUTHOR), Hugo, Cristelle¹ (AUTHOR), Kossyvakis, Athanassios¹ (AUTHOR), Roy, Shubhendu Sen¹ (AUTHOR), Kelesidis, Theodoros¹ (AUTHOR) tkelesidis@mednet.ucla.edu

Source: Journal of Infectious Diseases. Jul2023, Vol. 228 Issue 1, p59-63. 5p.

Subject Terms: *HIV infections, *MITOCHONDRIAL DNA, *MITOCHONDRIAL pathology, *LABORATORY mice, *ANIMAL disease models, *HIV

A Nrf2-OSGIN1&2-HSP70 axis mediates cigarette smoke-induced endothelial detachment: implications for plaque erosion.

Authors: Satta, Sandro^1,2 (AUTHOR), Beal, Robert¹ (AUTHOR), Smith, Rhys¹ (AUTHOR), Luo, Xing³ (AUTHOR), Ferris, Glenn R¹ (AUTHOR), Langford-Smith, Alex¹ (AUTHOR), Teasdale, Jack⁴ (AUTHOR), Ajime, Tom Tanjeko⁵ (AUTHOR), Serré, Jef⁵ (AUTHOR), Hazell, Georgina⁴ (AUTHOR), Newby, Graciela Sala⁴ (AUTHOR), Johnson, Jason L⁴ (AUTHOR), Kurinna, Svitlana⁶ (AUTHOR), Humphries, Martin J⁶ (AUTHOR), Gayan-Ramirez, Ghislaine⁵ (AUTHOR), Libby, Peter⁷ (AUTHOR), Degens, Hans^1,8 (AUTHOR), Yu, Bo³ (AUTHOR), Johnson, Thomas⁹ (AUTHOR), Alexander, Yvonne¹ (AUTHOR)

Source: Cardiovascular Research. Jul2023, Vol. 119 Issue 9, p1869-1882. 14p.

Subject Terms: *EROSION, *CIGARETTES, *ACUTE coronary syndrome, *FOCAL adhesions, *CIGARETTE smoke

Discovery of novel functionalized 1, 2, 4-triazoles as PARP-1 inhibitors in breast cancer: Design, synthesis and antitumor activity evaluation

Authors: Boraei, Ahmed T.A., Singh, Pankaj K., Sechi, Mario, Satta, Sandro

Source: European journal of medicinal chemistry. 182

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100091127803.0x000001&indx=1&recIds=ETOCvdc_100091127803.0x000001

Microfluidic Organ-Chips and Stem Cell Models in the Fight Against COVID-19.

Authors: Satta, Sandro, Rockwood, Sarah J., Wang, Kaidong, Wang, Shaolei, Mozneb, Maedeh, Arzt, Madelyn, Hsiai, Tzung K., Sharma, Arun

Source: Circulation Research; 5/12/2023, Vol. 132 Issue 10, p1405-1424, 20p

Ectodomain shedding of proteins important for SARS-CoV-2 pathogenesis in plasma of tobacco cigarette smokers compared to electronic cigarette vapers: a cross-sectional study.

Authors: Kelesidis, Theodoros, Sharma, Madhav, Satta, Sandro, Tran, Elizabeth, Gupta, Rajat, Araujo, Jesus A., Middlekauff, Holly R.

Source: Journal of Molecular Medicine; Mar2023, Vol. 101 Issue 3, p327-335, 9p

Subject Terms: ELECTRONIC cigarettes, POST-acute COVID-19 syndrome, CIGARETTE smokers, SARS-CoV-2, PEPTIDES

The role of oxidative stress in the pathogenesis of infections with coronaviruses.

Authors: Gain, Chandrima, Sihyeong Song, Angtuaco, Tyler, Satta, Sandro, Kelesidis, Theodoros

Source: Frontiers in Microbiology; 1/12/2023, Vol. 14, p01-17, 17p

Subject Terms: OXIDATIVE stress, CORONAVIRUS diseases, CORONAVIRUSES, COVID-19, LUNGS, RESPIRATORY infections

Chapter Four - Endothelial mechanotransduction in cardiovascular development and regeneration: emerging approaches and animal models

Authors: Cavallero, Susana, Blázquez-Medela, Ana M., Satta, Sandro, Hsiai, Tzung K. ^*

Source: In Current Topics in Membranes 2021 87:131-151

Engineering viral genomics and nano-liposomes in microfluidic platforms for patient-specific analysis of SARS-CoV-2 variants.

Authors: Satta, Sandro, Shahabipour, Fahimeh, Wei Gao, Lentz, Steven R., Perlman, Stanley, Ashammakhi, Nureddin, Tzung Hsiai

Source: Theranostics; 2022, Vol. 12 Issue 10, p4779-4790, 12p

An engineered nano-liposome-human ACE2 decoy neutralizes SARS-CoV-2 Spike protein-induced inflammation in both murine and human macrophages.

Authors: Satta, Sandro, Zhaojie Meng, Hernandez, Rebecca, Cavallero, Susana, Tong Zhou, Hsiai, Tzung K., Changcheng Zhou

Source: Theranostics; 2022, Vol. 12 Issue 6, p2639-2657, 19p

NRF2-MEDIATED UPREGULATION OF OSGIN1 AND OSGIN2 TRIGGERS CELL DETACHMENT THROUGH DYSREGULATED AUTOPHAGY — A POTENTIAL MECHANISM FOR ENDOTHELIAL EROSION OVERLYING STENOTIC PLAQUES
British Atherosclerosis Society (Annual meeting)

Authors: Satta, Sandro, Mcelroy, Michael, Hazell, Georgina, Teasdale, Jack, Sala-Newby, Graciela

Source: Cardiovascular research. 114(Supplement 2):S10-S10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN605339382&indx=1&recIds=ETOCCN605339382

A hybrid of light-field and light-sheet imaging to study myocardial function and intracardiac blood flow during zebrafish development.

Authors: Wang, Zhaoqiang, Ding, Yichen, Satta, Sandro, Roustaei, Mehrdad, Fei, Peng, Hsiai, Tzung K.

Source: PLoS Computational Biology; 7/6/2021, Vol. 17 Issue 7, p1-14, 14p, 1 Color Photograph, 1 Diagram, 1 Chart, 1 Graph

Subject Terms: BLOOD flow, HYBRID systems, PARTICLE tracking velocimetry, CONCEPTION, DIAGNOSTIC imaging, MORPHOGENESIS, CARDIAC contraction