Butyrophilin 2a2 (Btn2a2) expression on thymic epithelial cells promotes central T cell tolerance and prevents autoimmune disease

Authors: Frech, Michael, Danzer, Heike, Uchil, Pooja, Azizov, Vugar, Schmid, Eva, Schälter, Fabian, Dürholz, Kerstin, Mauro, Daniele, Rauber, Simon, Muñoz, Luis, Taher, Leila, Ciccia, Francesco, Schober, Kilian, Irla, Magali, Sarter, Kerstin, Schett, Georg, Zaiss, Mario M.

Source: In Journal of Autoimmunity September 2023 139

Acetate, a metabolic product of Heligmosomoides polygyrus, facilitates intestinal epithelial barrier breakdown in a FFAR2-dependent manner

Authors: Schälter, Fabian, Frech, Michael, Dürholz, Kerstin, Lucas, Sébastien, Sarter, Kerstin, Lebon, Luc, Esser-von Bieren, Julia, Dubey, Lalit K., Voehringer, David, Schett, Georg, Harris, Nicola L., Zaiss, Mario M.

Source: In International Journal for Parasitology August 2022 52(9):591-601

Type 2 innate lymphoid cells inhibit the differentiation of osteoclasts and protect from ovariectomy-induced bone loss

Authors: Omata, Yasunori, Frech, Michael, Lucas, Sébastien, Primbs, Tatjana, Knipfer, Lisa, Wirtz, Stefan, Kadono, Yuho, Saito, Taku, Tanaka, Sakae, Sarter, Kerstin, Schett, Georg, Zaiss, Mario M.

Source: In Bone July 2020 136

Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice

Authors: Omata, Yasunori, Frech, Michael, Primbs, Tatjana, Lucas, Sébastien, Andreev, Darja, Scholtysek, Carina, Sarter, Kerstin, Kindermann, Markus, Yeremenko, Nataliya, Baeten, Dominique L., Andreas, Nico, Kamradt, Thomas, Bozec, Aline, Ramming, Andreas, Krönke, Gerhard, Wirtz, Stefan, Schett, Georg, Zaiss, Mario M.

Source: In Cell Reports 3 July 2018 24(1):169-180

CCL19‐Positive Lymph Node Stromal Cells Govern the Onset of Inflammatory Arthritis via Tropomyosin Receptor Kinase.

Authors: Schälter, Fabian, Azizov, Vugar, Frech, Michael, Dürholz, Kerstin, Schmid, Eva, Hendel, Anna, Sarfati, Ilann, Maeda, Yuichi, Sokolova, Maria, Miyagawa, Ippei, Focke, Kristin, Sarter, Kerstin, van Baarsen, Lisa G. M., Krautwald, Stefan, Schett, Georg, Zaiss, Mario M.

Source: Arthritis & Rheumatology; Jun2024, Vol. 76 Issue 6, p857-868, 12p

Subject Terms: INFLAMMATION prevention, ARTHRITIS prevention, LYMPH nodes, IN vitro studies, T cells, PROTEIN-tyrosine kinase inhibitors, IMMUNOGLOBULINS, MICE, STROMAL cells, ANIMAL experimentation, CYTOKINES, SEQUENCE analysis

Interspecies Single‐Cell RNA‐Seq Analysis Reveals the Novel Trajectory of Osteoclast Differentiation and Therapeutic Targets

Authors: Omata, Yasunori, Okada, Hiroyuki, Uebe, Steffen, Izawa, Naohiro, Ekici, Arif B., Sarter, Kerstin, Saito, Taku, Schett, Georg, Tanaka, Sakae, Zaiss, Mario M.

Source: JBMR plus. 6(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156083027.0x000001&indx=1&recIds=ETOCvdc_100156083027.0x000001

Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss

Authors: Lucas, Sébastien, Omata, Yasunori, Hofmann, Jörg, Böttcher, Martin, Iljazovic, Aida, Sarter, Kerstin, Albrecht, Olivia, Schulz, Oscar, Krishnacoumar, Brenda, Krönke, Gerhard, Herrmann, Martin, Mougiakakos, Dimitrios, Strowig, Till, Schett, Georg, Zaiss, Mario

Source: Nature communications. 9(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100100188108.0x000001&indx=1&recIds=ETOCvdc_100100188108.0x000001

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation

Authors: Zaiss, Mario M., Rapin, Alexis, Lebon, Luc, Dubey, Lalit Kumar, Mosconi, Ilaria, Sarter, Kerstin, Piersigilli, Alessandra, Menin, Laure, Walker, Alan W., Rougemont, Jacques, Paerewijck, Oonagh, Geldhof, Peter, McCoy, Kathleen D., Macpherson, Andrew J., Croese, John, Giacomin, Paul R., Loukas, Alex, Junt, Tobias, Marsland, Benjamin J., Harris, Nicola L.

Source: In Immunity 17 November 2015 43(5):998-1010

Inflammatory arthritis and systemic bone loss are attenuated by gastrointestinal helminth parasites

Authors: Sarter, Kerstin, Kulagin, Manuel, Schett, Georg, Harris, Nicola L., Zaiss, Mario M.

Source: Autoimmunity. 50(3):151-157

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097810573.0x000001&indx=1&recIds=ETOCvdc_100097810573.0x000001

Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes

Authors: Sarter, Kerstin, Leimgruber, Elisa, Gobet, Florian, Agrawal, Vishal, Dunand-Sauthier, Isabelle, Barras, Emmanuèle, Mastelic-Gavillet, Béatris, Kamath, Arun, Fontannaz, Paola, Guéry, Leslie

Source: Journal of experimental medicine. 213(2):177-188

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN605321159&indx=1&recIds=ETOCRN605321159

Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis

Authors: Tajik, Narges, Frech, Michael, Schulz, Oscar, Schälter, Fabian, Lucas, Sébastien, Azizov, Vugar, Dürholz, Kerstin, Steffen, Franziska, Omata, Yasunori, Rings, Andreas, Bertog, Marko, Rizzo, Aroldo, Iljazovic, Aida, Basic, Marijana, Kleyer, Arnd, Culemann, Stephan, Krönke, Gerhard, Luo, Yubin, Überla, Klaus, Gaipl, Udo S., Frey, Benjamin, Strowig, Till, Sarter, Kerstin, Bischoff, Stephan C., Wirtz, Stefan, Cañete, Juan D., Ciccia, Francesco, Schett, Georg, Zaiss, Mario M.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174614978.0x000001&indx=1&recIds=ETOCvdc_100174614978.0x000001

Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis

Authors: Azizov, Vugar, Dietel, Katharina, Steffen, Franziska, Dürholz, Kerstin, Meidenbauer, Julia, Lucas, Sébastien, Frech, Michael, Omata, Yasunori, Tajik, Narges, Knipfer, Lisa, Kolenbrander, Anne, Seubert, Silvia, Lapuente, Dennis, Sokolova, Maria V., Hofmann, Jörg, Tenbusch, Matthias, Ramming, Andreas, Steffen, Ulrike, Nimmerjahn, Falk, Linker, Ralf, Wirtz, Stefan, Herrmann, Martin, Temchura, Vladimir, Sarter, Kerstin, Schett, Georg, Zaiss, Mario M.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174614431.0x000001&indx=1&recIds=ETOCvdc_100174614431.0x000001

12/15-Lipoxygenase Orchestrates the Clearance of Apoptotic Cells and Maintains Immunologic Tolerance

Authors: Uderhardt, Stefan, Herrmann, Martin, Oskolkova, Olga V., Aschermann, Susanne, Bicker, Wolfgang, Ipseiz, Natacha, Sarter, Kerstin, Frey, Benjamin, Rothe, Tobias, Voll, Reinhard, Nimmerjahn, Falk, Bochkov, Valery N., Schett, Georg, Krönke, Gerhard

Source: In Immunity 25 May 2012 36(5):834-846

˜Theœ role of galectins in clearance and immunogenicity of apoptotic and secondary necrotic cells = ˜Dieœ Rolle der Galektine in der Clearance und Immunogenität apoptotischer und sekundär nekrotischer Zellen

Authors: Sarter, Kerstin

Availability: http://data.europeana.eu/aggregation/europeana/2048441/item_MEWZMRGRXIQZF3ZWTONEJGN3UURG4IVN

Autoimmunity and chronic inflammation — Two clearance-related steps in the etiopathogenesis of SLE

Authors: Muñoz, Luis E., Janko, Christina, Schulze, Connie, Schorn, Christine, Sarter, Kerstin, Schett, Georg, Herrmann, Martin

Source: In Autoimmunity Reviews 2010 10(1):38-42

Clearance deficiency and systemic lupus erythematosus (SLE)

Authors: Gaipl, Udo S., Munoz, Luis E., Grossmayer, Gerhard, Lauber, Kirsten, Franz, Sandra, Sarter, Kerstin, Voll, Reinhard E., Winkler, Thomas, Kuhn, Annegret, Kalden, Joachim, Kern, Peter, Herrmann, Martin

Source: In Journal of Autoimmunity 2007 28(2):114-121

Permanent sex inversion in 1-year-old juveniles of the protogynous dusky grouper ( Epinephelus marginatus) using controlled-release 17α-methyltestosterone implants

Authors: Sarter, Kerstin, Papadaki, Maria, Zanuy, Silvia, Mylonas, Constantinos C.

Source: In Aquaculture 2006 256(1):443-456

Btn2a2 Regulates ILC2–T Cell Cross Talk in Type 2 Immune Responses.

Authors: Frech, Michael, Omata, Yasunori, Schmalzl, Angelika, Wirtz, Stefan, Taher, Leila, Schett, Georg, Zaiss, Mario M., Sarter, Kerstin

Source: Frontiers in Immunology; 1/25/2022, Vol. 13, p1-14, 14p

Subject Terms: IMMUNE response, HELMINTHIASIS, T cells, INNATE lymphoid cells, CELLULAR control mechanisms

RANKL-Induced Btn2a2 – A T Cell Immunomodulatory Molecule – During Osteoclast Differentiation Fine-Tunes Bone Resorption.

Authors: Frech, Michael, Schuster, Gregor, Andes, Fabian T., Schett, Georg, Zaiss, Mario M., Sarter, Kerstin

Source: Frontiers in Endocrinology; 8/4/2021, Vol. 12, p1-10, 10p

Subject Terms: OSTEOCLASTS, BONE resorption, T cells, EXPERIMENTAL arthritis, HOMEOSTASIS, MONOCYTES, MOLECULES

Sweet clearance: Involvement of cell surface glycans in the recognition of apoptotic cells.

Authors: Sarter, Kerstin¹ (AUTHOR), Mierke, Claudia² (AUTHOR), Beer, Alexandra¹ (AUTHOR), Frey, Benjamin³ (AUTHOR), Führnrohr, Barbara G⁴ (AUTHOR), Schulze, Connie¹ (AUTHOR), Franz, Sandra¹ (AUTHOR) sandra.franz@med3.imed.uni-erlangen.de

Source: Autoimmunity. Jun2007, Vol. 40 Issue 4, p345-348. 4p. 1 Chart.

Subject Terms: *LECTINS, *CELLS, *APOPTOSIS, *CELLULAR recognition, *IMMUNE system