Mitohormesis : la clé de voûte de la résistance thérapeutique des cellules cancéreuses

Authors: Boët, Emeline, Saland, Estelle, Skuli, Sarah, Griessinger, Emmanuel, Sarry, Jean-Emmanuel

Source: Comptes Rendus Biologies, Vol 347, Iss G1, Pp 59-75 (2024)

Subject Terms: Mitochondries, Mitohormesis, Oncométabolisme, Résistances thérapeutiques, Leucémies aiguës myéloides, Cancer, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.154/; https://doaj.org/toc/1768-3238

Access URL: https://doaj.org/article/0980ae54c4f140168356d5bcbf1b1a95

AMPK activation induces immunogenic cell death in AML

Authors: Mondesir, Johanna, Ghisi, Margherita, Poillet, Laura, Bossong, Robert A., Kepp, Oliver, Kroemer, Guido, Sarry, Jean-Emmanuel, Tamburini, Jérôme, Lane, Andrew A.

Source: In Blood Advances 26 December 2023 7(24):7585-7596

Meeting report of the 4th biennial Metabolism and Cancer symposium

Authors: Abdel Hadi, Nadine, Boet, Emeline, Lahalle, Airelle, Lauture, Laura, Refeyton, Alice, Reyes‐Castellanos, Gabriela, Caplet, Nathalie, Carrier, Alice, Le Cam, Laurent, Mazure, Nathalie M., Ricci, Jean‐Ehrland, Rocchi, Stéphane, Sarry, Jean‐Emmanuel, Vasseur, Sophie, Vlaski‐Lafarge, Marija, Rossignol, Rodrigue, Bost, Frédéric

Source: FEBS journal. 289(18):5516-5526

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161222071.0x000001&indx=1&recIds=ETOCvdc_100161222071.0x000001

AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia

Authors: Grenier, Adrien, Poulain, Laury, Mondesir, Johanna, Jacquel, Arnaud, Bosc, Claudie, Stuani, Lucille, Mouche, Sarah, Larrue, Clement, Sahal, Ambrine, Birsen, Rudy, Ghesquier, Victoria, Decroocq, Justine, Mazed, Fetta, Lambert, Mireille, Andrianteranagna, Mamy, Viollet, Benoit, Auberger, Patrick, Lane, Andrew A., Sujobert, Pierre, Bouscary, Didier, Sarry, Jean-Emmanuel, Tamburini, Jerome

Source: In Cell Reports 4 January 2022 38(1)

Autophagy is a major metabolic regulator involved in cancer therapy resistance

Authors: Poillet-Perez, Laura, Sarry, Jean-Emmanuel, Joffre, Carine

Source: In Cell Reports 17 August 2021 36(7)

Reference Values for Hematology, Plasma Biochemistry, Bone Marrow Cytology and Bone Histology of NOD.Cg-Prkdc^s^c^i^d Il2rg^t^m^1^W^j^l/SzJ Immunodeficient Mice

Authors: Layssol-Lamour, Catherine J., Sarry, Jean-Emmanuel, Braun, Jean-Pierre D., Trumel, Catherine, Bourgès-Abella, Nathalie H.

Source: Journal of the American Association for Laboratory Animal Science. 60(1):4-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626300363&indx=1&recIds=ETOCRN626300363

Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3‐ITD‐driven acute myeloid leukemia

Authors: Lopez‐Reyes, Rosa G., Quinet, Grégoire, Gonzalez‐Santamarta, Maria, Larrue, Clément, Sarry, Jean‐Emmanuel, Rodriguez, Manuel S.

Source: FEBS open bio. 11(1):48-60

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114204387.0x000001&indx=1&recIds=ETOCvdc_100114204387.0x000001

Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation

Authors: Dembitz, Vilma, Lawson, Hannah, Burt, Richard, Natani, Sirisha, Philippe, Céline, James, Sophie C., Atkinson, Samantha, Durko, Jozef, Wang, Lydia M., Campos, Joana, Magee, Aoife M. S., Woodley, Keith, Austin, Michael J., Rio-Machin, Ana, Casado, Pedro, Bewicke-Copley, Findlay, Rodriguez Blanco, Giovanny, Pereira-Martins, Diego, Oudejans, Lieve, Boet, Emeline, von Kriegsheim, Alex, Schwaller, Juerg, Finch, Andrew J., Patel, Bela, Sarry, Jean-Emmanuel, Tamburini, Jerome, Schuringa, Jan Jacob, Hazlehurst, Lori, Copland III, John A., Yuneva, Mariia, Peck, Barrie, Cutillas, Pedro, Fitzgibbon, Jude, Rouault-Pierre, Kevin, Kranc, Kamil, Gallipoli, Paolo

Source: Leukemia; November 2024, Vol. 38 Issue: 11 p2395-2409, 15p

Cytidine deaminase-dependent mitochondrial biogenesis as a potential vulnerability in pancreatic cancer cells.

Authors: Frances, Audrey, Lumeau, Audrey, Bery, Nicolas, Gayral, Marion, Stuani, Lucille, Sorbara, Marie, Saland, Estelle, Pagan, Delphine, Hanoun, Naïma, Torrisani, Jérôme, Lemarié, Anthony, Portais, Jean-Charles, Buscail, Louis, Dusetti, Nelson, Sarry, Jean-Emmanuel, Cordelier, Pierre

Source: Communications Biology; 8/30/2024, Vol. 7 Issue 1, p1-11, 11p

Subject Terms: PANCREATIC cancer, CANCER cells, GLYCOLYSIS, CELL metabolism, CYTIDINE deaminase, MITOCHONDRIA

People: PASTEUR, Louis, 1822-1895

Targeting ferritinophagy impairs quiescent cancer stem cells in acute myeloid leukemia in vitro and in vivo models.

Authors: Larrue, Clement, Mouche, Sarah, Angelino, Paolo, Sajot, Maxime, Birsen, Rudy, Kosmider, Olivier, Mckee, Thomas, Vergez, François, Recher, Christian, Mas, Véronique Mansat-De, Gu, Qiong, Xu, Jun, Tsantoulis, Petros, Sarry, Jean-Emmanuel, Tamburini, Jerome

Source: Science Translational Medicine; 7/24/2024, Vol. 16 Issue 757, p1-15, 15p

Subject Terms: ACUTE myeloid leukemia, CANCER stem cells, AUTOPHAGY, PRELEUKEMIA, MYELOID cells, HEMATOLOGIC malignancies, IRON metabolism

Ferritin heavy/light chain (FTH1/FTL) expression, serum ferritin levels, and their functional as well as prognostic roles in acute myeloid leukemia

Authors: Bertoli, Sarah, Paubelle, Etienne, Bérard, Emilie, Saland, Estelle, Thomas, Xavier, Tavitian, Suzanne, Larcher, Marie‐Virginie, Vergez, François, Delabesse, Eric, Sarry, Audrey, Huguet, Françoise, Larrue, Clément, Bosc, Claudie, Farge, Thomas, Sarry, Jean Emmanuel, Michallet, Mauricette, Récher, Christian

Source: European journal of haematology. 102(2):131-142

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100095072300.0x000001&indx=1&recIds=ETOCvdc_100095072300.0x000001

Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia

Authors: Stuani, Lucille, Sabatier, Marie, Sarry, Jean-Emmanuel

Source: BMC biology. 17(1):1-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189304977.0x000001&indx=1&recIds=ETOCvdc_100189304977.0x000001

Oncogenic KIT mutations induce STAT3-dependent autophagy to support cell proliferation in acute myeloid leukemia

Authors: Larrue, Clément, Heydt, Quentin, Saland, Estelle, Boutzen, Héléna, Kaoma, Tony, Sarry, Jean-Emmanuel, Joffre, Carine, Récher, Christian

Source: Oncogenesis. 8(8):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185365023.0x000001&indx=1&recIds=ETOCvdc_100185365023.0x000001

Resistance Is Futile: Targeting Mitochondrial Energetics and Metabolism to Overcome Drug Resistance in Cancer Treatment

Authors: Bosc, Claudie, Selak, Mary A., Sarry, Jean-Emmanuel

Source: In Cell Metabolism 7 November 2017 26(5):705-707

Microenvironmental Aspartate Preserves Leukemic Cells from Therapy-Induced Metabolic Collapse

Authors: Stuani, Lucille, Sarry, Jean-Emmanuel

Source: Cell metabolism. 32(3):321-323

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120073073.0x000001&indx=1&recIds=ETOCvdc_100120073073.0x000001

Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy

Authors: Moschoi, Ruxanda, Imbert, Véronique, Nebout, Marielle, Chiche, Johanna, Mary, Didier, Prebet, Thomas, Saland, Estelle, Castellano, Rémy, Pouyet, Laurent, Collette, Yves, Vey, Norbert, Chabannon, Christian, Recher, Christian, Sarry, Jean-Emmanuel, Alcor, Damien, Peyron, Jean-François, Griessinger, Emmanuel

Source: In Blood 14 July 2016 128(2):253-264

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53

Authors: Riscal, Romain, Schrepfer, Emilie, Arena, Giuseppe, Cissé, Madi Y., Bellvert, Floriant, Heuillet, Maud, Rambow, Florian, Bonneil, Eric, Sabourdy, Frédérique, Vincent, Charles, Ait-Arsa, Imade, Levade, Thierry, Thibaut, Pierre, Marine, Jean-Christophe, Portais, Jean-Charles, Sarry, Jean-Emmanuel, Le Cam, Laurent, Linares, Laetitia K.

Source: In Molecular Cell 16 June 2016 62(6):890-902

Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells

Authors: Larrue, Clément, Saland, Estelle, Boutzen, Héléna, Vergez, François, David, Marion, Joffre, Carine, Hospital, Marie-Anne, Tamburini, Jérôme, Delabesse, Eric, Manenti, Stéphane, Sarry, Jean Emmanuel, Récher, Christian ^*

Source: In Blood 16 February 2016 127(7):882-892

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

Authors: Jacque, Nathalie, Ronchetti, Anne Marie, Larrue, Clément, Meunier, Godelieve, Birsen, Rudy, Willems, Lise, Saland, Estelle, Decroocq, Justine, Maciel, Thiago Trovati, Lambert, Mireille, Poulain, Laury, Hospital, Marie Anne, Sujobert, Pierre, Joseph, Laure, Chapuis, Nicolas, Lacombe, Catherine, Moura, Ivan Cruz, Demo, Susan, Sarry, Jean Emmanuel, Recher, Christian, Mayeux, Patrick, Tamburini, Jérôme, Bouscary, Didier ^*

Source: In Blood 10 September 2015 126(11):1346-1356

Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells

Authors: Larrue, Clément, Guiraud, Nathan, Mouchel, Pierre-Luc, Dubois, Marine, Farge, Thomas, Gotanègre, Mathilde, Bosc, Claudie, Saland, Estelle, Nicolau-Travers, Marie-Laure, Sabatier, Marie, Serhan, Nizar, Sahal, Ambrine, Boet, Emeline, Mouche, Sarah, Heydt, Quentin, Aroua, Nesrine, Stuani, Lucille, Kaoma, Tony, Angenendt, Linus, Mikesch, Jan-Henrik, Schliemann, Christoph, Vergez, François, Tamburini, Jérôme, Récher, Christian, Sarry, Jean-Emmanuel

Source: Nature communications. 12(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193114859.0x000001&indx=1&recIds=ETOCvdc_100193114859.0x000001