Comparative effectiveness of subcutaneous sarilumab 200 mg biweekly, subcutaneous Tocilizumab 162 mg biweekly, and intravenous Tocilizumab 8 mg/kg every 4 weeks in patients with rheumatoid arthritis: a prospective cohort study

Authors: Akira Onishi, Masao Tanaka, Takayuki Fujii, Koichi Murata, Kosaku Murakami, Motomu Hashimoto, Ryu Watanabe, Yuji Nozaki, Chisato Ashida, Wataru Yamamoto, Hirotaka Yamada, Sho Sendo, Kosuke Ebina, Hidehiko Makino, Yonsu Son, Yumiko Wada, Kenichiro Hata, Shuichi Matsuda, Akio Morinobu

Source: Arthritis Research & Therapy, Vol 27, Iss 1, Pp 1-11 (2025)

Subject Terms: Rheumatoid arthritis, Antirheumatic agents, Interleukin-6 inhibitors, Tocilizumab, Sarilumab, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/fc8310747e0347119acb51116c294e72

Real-world Effectiveness of Sarilumab in RA: Results from the Open-label, Prospective, Single-arm Observational PROFILE Study

Authors: Alan Kivitz, Jacques Eric Gottenberg, Martin Bergman, Chunfu Qiu, Hubert van Hoogstraten, Ron de Nijs, Louis Bessette

Source: Rheumatology and Therapy, Vol 11, Iss 6, Pp 1533-1550 (2024)

Subject Terms: Antirheumatic agents, Patient-reported outcome measures, Quality of life, Real-world, Rheumatoid arthritis, Sarilumab, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/2198-6576; https://doaj.org/toc/2198-6584

Access URL: https://doaj.org/article/f98da2876c6e42148dfe1f0f8228c479

Investigating the impact of Tocilizumab, Sarilumab, and Anakinra on clinical outcomes in COVID-19: A systematic review and meta-analysis

Authors: Yousef Jafari Abarghan, Mohammad Heiat, Abolfazl Jahangiri, Mohammad Hossein Peypar, Mahdi Abdorrashidi, Amirmohammad Tohidinia, Mahmood Salesi, Shahrzad Tajik, Farnaz Farzaneh Dehkordi, Hamid Sedighian

Source: International Journal of Cardiology: Heart & Vasculature, Vol 54, Iss , Pp 101483- (2024)

Subject Terms: Anakinra, COVID-19, Monoclonal antibody, Randomized Controlled Trial, Sarilumab, SARS-CoV-2, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352906724001490; https://doaj.org/toc/2352-9067

Access URL: https://doaj.org/article/2bf9634225bf47f0b27fa342506b356b

Successful Salvage Therapy of Late-onset Arterial Disorders due to Recurrent Vasospasms Following Free Flap Transfer under the IL-6 and TNF-α Signaling-downregulated Environment: A Case Report

Authors: Jun-ya Niwa, Koichi Gonda, Kazufumi Tachi

Source: Journal of Plastic and Reconstructive Surgery, Vol 3, Iss 2, Pp 83-88 (2024)

Subject Terms: iguratimod, il-6, sarilumab, tnf-α, vasospasms, Surgery, RD1-811

File Description: electronic resource

Relation: https://www.jstage.jst.go.jp/article/jprs/3/2/3_2023-0049/_pdf/-char/en; https://doaj.org/toc/2436-259X

Access URL: https://doaj.org/article/7d13ed87597c40498ae85694985a2c4e

TAFRO syndrome associated with C3 nephropathy (an analysis of clinical experience)

Authors: I. V. Pozharov, A. O. Grigorevskaya, G. R. Setdikova, E. S. Stolyarevich

Source: Klinicist, Vol 17, Iss 3, Pp 42-49 (2024)

Subject Terms: tafro syndrome, castleman disease, c3 glomerulopathy, bone marrow fibrosis, il-6 inhibitors, sarilumab, ascites, glomerulonephritis, thrombocytopenia, Medicine

File Description: electronic resource

Relation: https://klinitsist.abvpress.ru/Klin/article/view/560; https://doaj.org/toc/1818-8338

Access URL: https://doaj.org/article/01eb18e6b3f84ae7a86575efc2546013

Blockade of the interleukin-6 signaling pathway in rheumatoid arthritis: Effects on obesity, adipocytokines and glucose metabolism

Authors: L. V. Kondratyeva, Yu. S. Gorbunova, T. V. Popkova, E. L. Nasonov

Source: Научно-практическая ревматология, Vol 61, Iss 6, Pp 658-666 (2024)

Subject Terms: interleukin 6, tocilizumab, sarilumab, obesity, adipocytokines, adiponectin, leptin, resistin, visfatin, insulin resistance, diabetes mellitus, glycated hemoglobin, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://rsp.mediar-press.net/rsp/article/view/3471; https://doaj.org/toc/1995-4484; https://doaj.org/toc/1995-4492

Access URL: https://doaj.org/article/20fae97266bd4434bed27e5c42d753fc

Sarilumab is not Inferior to Tocilizumab in the Treatment of Cytokine Release Syndrome in COVID-19

Authors: V. T. Ivashkin, R. V. Maslennikov, E. V. Vasilieva, M. L. Chipurik, P. A. Semikova, V. V. Semenets, T. A. Russkova

Source: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 33, Iss 5, Pp 54-64 (2023)

Subject Terms: coronavirus, cytokine release syndrome, interleukin-6, tocilizumab, sarilumab, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://www.gastro-j.ru/jour/article/view/676; https://doaj.org/toc/1382-4376; https://doaj.org/toc/2658-6673

Access URL: https://doaj.org/article/1596e4d0681a4639955eb64d26e77009

Impact of IL6R genetic variants on treatment efficacy and toxicity response to sarilumab in rheumatoid arthritis

Authors: Luis Sainz, Pau Riera, Patricia Moya, Sara Bernal, Jordi Casademont, Cesar Díaz-Torné, Ana Milena Millán, Hye Sang Park, Adriana Lasa, Hector Corominas

Source: Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-10 (2023)

Subject Terms: IL6R, Genetic variants, Sarilumab, Rheumatoid arthritis, Predictive factors, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/0444fe7ddf56436ab6f8401650ec4da3

A phase 3 randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with giant cell arteritis

Authors: Wolfgang A. Schmidt, Bhaskar Dasgupta, Jennifer Sloane, Angeliki Giannelou, Yuqing Xu, Sebastian H. Unizony, Sarah L. Mackie, Miguel A. Gonzalez-Gay, Robert Spiera, Kenneth J. Warrington, Peter M. Villiger, Michael C. Nivens, Bolanle Akinlade, Yong Lin, Frank Buttgereit, John H. Stone

Source: Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-16 (2023)

Subject Terms: Sarilumab, Giant cell arteritis, Glucocorticoids, Interleukin-6, Sustained remission, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/4519641ec60d4627b6d5c6d36c1bb6ac

A comparison of the effectiveness of different doses of tocilizumab and sarilumab in the treatment of severe COVID-19: a natural experiment due to drug shortages

Authors: Maaike C. Swets, Rob J. Moss, Flip Kor, Doranne Hilarius, Dirk Jan A.R. Moes, Willemijn EM Berkhout, Leon M. van den Toorn, Niels C. Gritters van den Oever, Renee de Valk, Frits R. Rosendaal, Nicole Hunfeld, Geert H. Groeneveld, Mark G.J. de Boer

Source: International Journal of Infectious Diseases, Vol 129, Iss , Pp 57-62 (2023)

Subject Terms: IL-6 inhibitor, COVID-19, SARS-CoV-2, Tocilizumab, Sarilumab, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971223000413; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/272003f490b749cda7c4f1c7f333c48d

Clinical Efficacy of Sarilumab Versus Upadacitinib Over 12 weeks: An Indirect Treatment Comparison

Authors: Thomas Huizinga, Ernest Choy, Amy Praestgaard, Hubert van Hoogstraten, Patrick R. LaFontaine, Patricia Guyot, Daniel Aletaha, Ulf Müller-Ladner, Yoshiya Tanaka, Jeffrey R. Curtis, Roy Fleischmann

Source: Rheumatology and Therapy, Vol 10, Iss 3, Pp 539-550 (2023)

Subject Terms: Rheumatoid arthritis, Sarilumab, Upadacitinib, Matching-adjusted indirect comparison, Simulated treatment comparison, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/2198-6576; https://doaj.org/toc/2198-6584

Access URL: https://doaj.org/article/d705218c26a84ae980d82074b13580e4

Polymyalgia Rheumatica Treated with Sarilumab

Authors: Anvitha Madhavaram, Bashar Kahaleh

Source: Translation, Vol 11, Iss 3 (2023)

Subject Terms: Polymyalgia Rheumatica, Sarilumab, Microscopic Polyangiitis, Rituximab, Medicine (General), R5-920

File Description: electronic resource

Relation: https://openjournals.utoledo.edu/index.php/translation/article/view/912; https://doaj.org/toc/2469-6706

Access URL: https://doaj.org/article/68a3cb11fc514a5baba97f9a98f01136

Clinical efficacy and safety of interleukin-6 receptor antagonists (tocilizumab and sarilumab) in patients with COVID-19: a systematic review and meta-analysis

Authors: Su-Yeon Yu, Dae-Hyup Koh, Miyoung Choi, Seungeun Ryoo, Kyungmin Huh, Joon Sup Yeom, Young Kyung Yoon

Source: Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1154-1165 (2022)

Subject Terms: COVID-19, tocilizumab, sarilumab, meta-analysis, systematic review, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/5bf940e2047a4397a0c2d4dc826980e9

Drug-induced liver injury following the use of tocilizumab or sarilumab in patients with coronavirus disease 2019

Authors: Qian Gao, Xuedong Yin, Boyu Tan, Junshi Wang, Jiayan Chen, Bin Zhao, Qiaoling Yang, Zhiling Li

Source: BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)

Subject Terms: Coronavirus disease 2019 (COVID-19), Tocilizumab, Sarilumab, Drug Induced Liver Injury, FAERS, Epidemiology, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/581ff79c85da47f5b83a2d2c01ca0d9b

Efficacy and safety of interleukin-6 receptor antagonists in adult patients admitted to intensive care unit with COVID-19: A systematic review and meta-analysis of randomized controlled trials

Authors: Rong Peng, Ting Yang, Yu Tong, Ji Wang, Hui Zhou, Minglong Yang, Junchen Zhu, Lijun Yang, Zheng Shi, Ya Liu

Source: Preventive Medicine Reports, Vol 34, Iss , Pp 102276- (2023)

Subject Terms: Tocilizumab, Sarilumab, COVID-19, Meta-analysis, Systematic review, Medicine

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211335523001675; https://doaj.org/toc/2211-3355

Access URL: https://doaj.org/article/0aed4c4633f54ade9c6f1cbdbd051755

Sarilumab use in severe Coronavirus Disease 2019 pneumonia

Authors: Ahmed M.A. El Fattah Amer, Doaa B Mousa

Source: Egyptian Journal of Chest Disease and Tuberculosis, Vol 72, Iss 2, Pp 191-193 (2023)

Subject Terms: coronavirus, interleukin-6, sarilumab, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2023;volume=72;issue=2;spage=191;epage=193;aulast=El; https://doaj.org/toc/0422-7638; https://doaj.org/toc/2090-9950

Access URL: https://doaj.org/article/2d1d106b074140f886800f33315e37e0

Association between low hemoglobin, clinical measures, and patient-reported outcomes in patients with rheumatoid arthritis: results from post hoc analyses of three phase III trials of sarilumab

Authors: Andrea Rubbert-Roth, Daniel E. Furst, Stefano Fiore, Amy Praestgaard, Vivian Bykerk, Clifton O. Bingham, Christina Charles-Schoeman, Gerd Burmester

Source: Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-11 (2022)

Subject Terms: Rheumatoid arthritis, Sarilumab, Patient-reported outcomes, Anemia, Hemoglobin, Radiographic outcomes, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/2297141dda5546b58a1730ec37efc1ff

Interleukin-6 inhibitors: from the therapy of immuno-inflammatory rheumatic diseases to use in COVID-19

Authors: N. V. Muravyeva, B. S. Belov

Source: Медицинский совет, Vol 0, Iss 11, Pp 88-94 (2022)

Subject Terms: interleukin 6, tocilizumab, sarilumab, immuno-inflammatory rheumatic diseases, rheumatoid arthritis, covid-19, cytokine storm syndrome, Medicine

File Description: electronic resource

Relation: https://www.med-sovet.pro/jour/article/view/6960; https://doaj.org/toc/2079-701X; https://doaj.org/toc/2658-5790

Access URL: https://doaj.org/article/de81d2e98f2e482a9beaaee3aaf410c3

Effect of Anti-Interleukin-6 Agents on Psychopathology in a Sample of Patients with Post-COVID-19 Syndrome: An Observational Study

Authors: Alessio Simonetti, Antonio Restaino, Evelina Bernardi, Ottavia Marianna Ferrara, Stella Margoni, Antonio Maria D’Onofrio, Federica Ranieri, Delfina Janiri, Vincenzo Galluzzo, Matteo Tosato, Georgios D. Kotzalidis, Francesco Landi, Gabriele Sani

Source: Brain Sciences, Vol 14, Iss 1, p 47 (2024)

Subject Terms: COVID-19, post-COVID-19 syndrome, Il-6, bevacizumab, sarilumab, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3425/14/1/47; https://doaj.org/toc/2076-3425

Access URL: https://doaj.org/article/30f388c03bc2426a9d46d89028680361

Sarilumab Administration in COVID-19 Patients: Literature Review and Considerations

Authors: Andrea Marino, Antonio Munafò, Egle Augello, Carlo Maria Bellanca, Carmelo Bonomo, Manuela Ceccarelli, Nicolò Musso, Giuseppina Cantarella, Bruno Cacopardo, Renato Bernardini

Source: Infectious Disease Reports, Vol 14, Iss 3, Pp 360-371 (2022)

Subject Terms: COVID-19, cytokines, IL-6, IL-6R, sarilumab, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://www.mdpi.com/2036-7449/14/3/40; https://doaj.org/toc/2036-7449

Access URL: https://doaj.org/article/27427e1e8836400083c48ab7fd070f83