pH-conditioning of recognition layers enables single-molecule affinity detections at 10E-20 molar

Authors: Macchia, Eleonora, Di Franco, Cinzia, Scandurra, Cecilia, Sarcina, Lucia, Piscitelli, Matteo, Catacchio, Michele, Caputo, Mariapia, Bollella, Paolo, Scamarcio, Gaetano, Torsi, Luisa

Subject Terms: Physics - Applied Physics

Access URL: http://arxiv.org/abs/2401.11801

Large-area bio-electronic sensors for early detection of pancreatic-biliary cancer protein markers

Authors: Sarcina, Lucia, Viola, Fabrizio, Modena, Francesco, Bollella, Paolo, Caironi, Mario, Esposito, Irene, Torsi, Luisa, Torricelli, Fabrizio, Macchia, Eleonora

Source: 2022 IEEE International Conference on Flexible and Printable Sensors and Systems (FLEPS) Flexible and Printable Sensors and Systems (FLEPS), 2022 IEEE International Conference on. :1-4 Jul, 2022

Relation: 2022 IEEE International Conference on Flexible and Printable Sensors and Systems (FLEPS)

Label-free electronic detection of peptide post-translational modification with functional enzyme-driven assay at the physical limit

Authors: Macchia, Eleonora, Björkström, Kim, Tewari, Amit, Eskonen, Ville, Luukkonen, Axel, Ghafari, Amir Mohammad, Sarcina, Lucia, Caputo, Mariapia, Tong-Ochoa, Natalia, Kopra, Kari, Pettersson, Fredrik, Gounani, Zahra, Torsi, Luisa, Härmä, Harri, Österbacka, Ronald

Source: In Cell Reports Physical Science 21 August 2024 5(8)

Large-Area Interfaces for Single-Molecule Label-free Bioelectronic Detection

Authors: Macchia, Eleonora, Torricelli, Fabrizio, Bollella, Paolo, Sarcina, Lucia, Tricase, Angelo, Di Franco, Cinzia, Österbacka, Ronald, Kovács-Vajna, Zsolt M., Scamarcio, Gaetano, Torsi, Luisa

Source: Chemical reviews. 122(4):4636-4699

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631438932&indx=1&recIds=ETOCRN631438932

A 4 × 4 Biosensor Array With a 42- μ W/Channel Multiplexed Current Sensitive Front-End Featuring 137-dB DR and Zeptomolar Sensitivity

Authors: Genco, Enrico, Fattori, Marco, Harpe, Pieter J. A., Modena, Francesco, Viola, Fabrizio Antonio, Caironi, Mario, Wheeler, May, Fichet, Guillaume, Torricelli, Fabrizio, Sarcina, Lucia, Macchia, Eleonora, Torsi, Luisa, Cantatore, Eugenio

Source: IEEE open journal of solid-state circuits. 2:193-207

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176753100.0x000001&indx=1&recIds=ETOCvdc_100176753100.0x000001

Electric Field Cycling of Physisorbed Antibodies Reduces Biolayer Polarization Dispersion.

Authors: Di Franco, Cinzia¹, Macchia, Eleonora^2,3, Catacchio, Michele², Caputo, Mariapia², Scandurra, Cecilia⁴, Sarcina, Lucia⁴, Bollella, Paolo⁴, Tricase, Angelo^2,3, Innocenti, Massimo⁵, Funari, Riccardo^6,7, Piscitelli, Matteo^1,6, Scamarcio, Gaetano^6,8, gaetano.scamarcio@uniba.it, Torsi, Luisa⁴, luisa.torsi@uniba.it

Source: Advanced Science; 1/9/2025, Vol. 12 Issue 1, p1-17, 17p

Perspectives on systematic optimization of ultrasensitive biosensors through experimental design.

Authors: Caputo, Mariapia, Tricase, Angelo, Marchianò, Verdiana, Scandurra, Cecilia, Piscitelli, Matteo, Sarcina, Lucia, Catacchio, Michele, Di Franco, Cinzia, Bollella, Paolo, Torsi, Luisa, Macchia, Eleonora

Source: Journal of Materials Chemistry C; 10/14/2024, Vol. 12 Issue 38, p15382-15400, 19p

Standalone operation of an EGOFET for ultra-sensitive detection of HIV

Authors: Sailapu, Sunil Kumar, Macchia, Eleonora, Merino-Jimenez, Irene, Esquivel, Juan Pablo, Sarcina, Lucia, Scamarcio, G., Minteer, Shelley D., Torsi, Luisa, Sabaté, Neus

Source: In Biosensors and Bioelectronics 15 May 2020 156

A Single‐Molecule Bioelectronic Portable Array for Early Diagnosis of Pancreatic Cancer Precursors

Authors: Genco, Enrico, Modena, Francesco, Sarcina, Lucia, Björkström, Kim, Brunetti, Celestino, Caironi, Mario, Caputo, Mariapia, Demartis, Virginia Maria, Di Franco, Cinzia, Frusconi, Giulia, Haeberle, Lena, Larizza, Piero, Mancini, Maria Teresa, Österbacka, Ronald, Reeves, William, Scamarcio, Gaetano, Scandurra, Cecilia, Wheeler, May, Cantatore, Eugenio, Esposito, Irene, Macchia, Eleonora, Torricelli, Fabrizio, Viola, Fabrizio Antonio, Torsi, Luisa

Source: Advanced materials. 35(42)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196433835.0x000001&indx=1&recIds=ETOCvdc_100196433835.0x000001

Extended Work Function Shift of Large‐Area Biofunctionalized Surfaces Triggered by a Few Single‐Molecule Affinity Binding Events

Authors: Di Franco, Cinzia, Macchia, Eleonora, Sarcina, Lucia, Ditaranto, Nicoletta, Khaliq, Aniqa, Torsi, Luisa, Scamarcio, Gaetano

Source: Advanced materials interfaces. 10(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193795011.0x000001&indx=1&recIds=ETOCvdc_100193795011.0x000001

Controlling the Binding Efficiency of Surface Confined Antibodies through the Design of Mixed Self‐Assembled Monolayers

Authors: Sarcina, Lucia, Delre, Pietro, Graziano, Giovanni, Stefanachi, Angela, Blasi, Davide, Picca, Rosaria A., Di Franco, Cinzia, Leonetti, Francesco, Scamarcio, Gaetano, Bollella, Paolo, Mangiatordi, Giuseppe F., Macchia, Eleonora, Torsi, Luisa

Source: Advanced materials interfaces. 10(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193788135.0x000001&indx=1&recIds=ETOCvdc_100193788135.0x000001

Enzyme based field effect transistor: State‐of‐the‐art and future perspectives

Authors: Sarcina, Lucia, Macchia, Eleonora, Tricase, Angelo, Scandurra, Cecilia, Imbriano, Anna, Torricelli, Fabrizio, Cioffi, Nicola, Torsi, Luisa, Bollella, Paolo

Source: Electrochemical science advances. 3(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185367332.0x000001&indx=1&recIds=ETOCvdc_100185367332.0x000001

Single Molecule with a Large Transistor – SiMoT cytokine IL‐6 Detection Benchmarked against a Chemiluminescent Ultrasensitive Immunoassay Array

Authors: Scandurra, Cecilia, Björkström, Kim, Sarcina, Lucia, Imbriano, Anna, Di Franco, Cinzia, Österbacka, Ronald, Bollella, Paolo, Scamarcio, Gaetano, Torsi, Luisa, Macchia, Eleonora

Source: Advanced materials technologies. 8(11)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185216889.0x000001&indx=1&recIds=ETOCvdc_100185216889.0x000001

Enzyme based amperometric wide field biosensors: Is single‐molecule detection possible?

Authors: Tricase, Angelo, Imbriano, Anna, Macchia, Eleonora, Sarcina, Lucia, Scandurra, Cecilia, Torricelli, Fabrizio, Cioffi, Nicola, Torsi, Luisa, Bollella, Paolo

Source: Electrochemical science advances. 3(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181985560.0x000001&indx=1&recIds=ETOCvdc_100181985560.0x000001

About the amplification factors in organic bioelectronic sensors

Authors: Macchia, Eleonora, Picca, Rosaria Anna, Manoli, Kyriaki, Di Franco, Cinzia, Blasi, Davide, Sarcina, Lucia, Ditaranto, Nicoletta, Cioffi, Nicola, Österbacka, Ronald, Scamarcio, Gaetano, Torricelli, Fabrizio, Torsi, Luisa

Source: Materials horizons. 7(4):999-1013

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108995640.0x000001&indx=1&recIds=ETOCvdc_100108995640.0x000001

Ultra-low HIV-1 p24 detection limits with a bioelectronic sensor

Authors: Macchia, Eleonora, Sarcina, Lucia, Picca, Rosaria Anna, Manoli, Kyriaki, Di Franco, Cinzia, Scamarcio, Gaetano, Torsi, Luisa

Source: Analytical and bioanalytical chemistry. 412(4):811-818

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161859965.0x000001&indx=1&recIds=ETOCvdc_100161859965.0x000001

Piercing the Shadows: Exploring the Influence of Signal Preprocessing on Interpreting Ultrasensitive Bioelectronic Sensor Data.

Authors: Caputo, Mariapia¹ (AUTHOR), Sarcina, Lucia² (AUTHOR), Scandurra, Cecilia² (AUTHOR), Catacchio, Michele¹ (AUTHOR), Piscitelli, Matteo³ (AUTHOR), Franco, Cinzia Di⁴ (AUTHOR), Bollella, Paolo² (AUTHOR), Scamarcio, Gaetano³ (AUTHOR), Torsi, Luisa² (AUTHOR) luisa.torsi@uniba.it, Macchia, Eleonora^1,5 (AUTHOR)

Source: ChemPlusChem. Sep2024, p1. 11p. 5 Illustrations.

Subject Terms: *SINGLE molecule detection, *FIELD-effect transistors, *TECHNOLOGY assessment, *MATHEMATICAL transformations, *PANCREATIC cysts, *ARACHNOID cysts

Analysis of Clinical Samples of Pancreatic Cyst's Lesions with A Multi‐Analyte Bioelectronic Simot Array Benchmarked Against Ultrasensitive Chemiluminescent Immunoassay.

Authors: Scandurra, Cecilia¹, Björkström, Kim², Caputo, Mariapia³, Sarcina, Lucia¹, Genco, Enrico⁴, Modena, Francesco⁵, Viola, Fabrizio Antonio⁵, Brunetti, Celestino⁶, Kovács‐Vajna, Zsolt M.⁷, Franco, Cinzia Di⁸, Haeberle, Lena⁹, Larizza, Piero⁶, Mancini, Maria Teresa⁶, Österbacka, Ronald², Reeves, William¹⁰, Scamarcio, Gaetano¹¹, Wheeler, May¹⁰, Caironi, Mario⁵, Cantatore, Eugenio⁴, Torricelli, Fabrizio⁷

Source: Advanced Science; 7/17/2024, Vol. 11 Issue 27, p1-14, 14p

A large-area organic transistor with 3D-printed sensing gate for noninvasive single-molecule detection of pancreatic mucinous cyst markers.

Authors: Sarcina, Lucia¹ (AUTHOR), Viola, Fabrizio² (AUTHOR), Modena, Francesco^2,3 (AUTHOR), Picca, Rosaria Anna^1,4 (AUTHOR), Bollella, Paolo¹ (AUTHOR), Di Franco, Cinzia¹ (AUTHOR), Cioffi, Nicola^1,4 (AUTHOR), Caironi, Mario² (AUTHOR), Österbacka, Ronald⁵ (AUTHOR), Esposito, Irene⁶ (AUTHOR), Scamarcio, Gaetano⁷ (AUTHOR), Torsi, Luisa^1,4,5 (AUTHOR), Torricelli, Fabrizio⁸ (AUTHOR) fabrizio.torricelli@unibs.it, Macchia, Eleonora^4,5,9 (AUTHOR) eleonora.macchia@abo.fi

Source: Analytical & Bioanalytical Chemistry. Jul2022, Vol. 414 Issue 18, p5657-5669. 13p.

Subject Terms: *PANCREATIC cysts, *ORGANIC semiconductors, *GENETIC markers, *TRANSISTORS, *NONINVASIVE diagnostic tests, *CURING, *ORGANIC field-effect transistors

Fast and Reliable Electronic Assay of a Xylella fastidiosa Single Bacterium in Infected Plants Sap

Authors: Sarcina, Lucia, Macchia, Eleonora, Loconsole, Giuliana, D'Attoma, Giusy, Bollella, Paolo, Catacchio, Michele, Leonetti, Francesco, Di Franco, Cinzia, Elicio, Vito, Scamarcio, Gaetano, Palazzo, Gerardo, Boscia, Donato, Saldarelli, Pasquale, Torsi, Luisa

Source: Advanced science. 9(30)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163286027.0x000001&indx=1&recIds=ETOCvdc_100163286027.0x000001