Heightened TLR7 signaling primes BCR-activated B cells in chronic graft-versus-host disease for effector functions

Authors: Bracken, Sonali J., Suthers, Amy N., DiCioccio, Rachel A., Su, Hsuan, Anand, Sarah, Poe, Jonathan C., Jia, Wei, Visentin, Jonathan, Basher, Fahmin, Jordan, Collin Z., McManigle, William C., Li, Zhiguo, Hakim, Frances T., Pavletic, Steven Z., Bhuiya, Nazmim S., Ho, Vincent T., Horwitz, Mitchell E., Chao, Nelson J., Sarantopoulos, Stefanie

Source: In Blood Advances 13 February 2024 8(3):667-680

Meibomian Gland Dysfunction: A Route of Ocular Graft-Versus-Host Disease Progression That Drives a Vicious Cycle of Ocular Surface Inflammatory Damage

Authors: Perez, Victor L., Mousa, Hazem M., Soifer, Matias, Beatty, Cole, Sarantopoulos, Stefanie, Saban, Daniel R., Levy, Robert B.

Source: American journal of ophthalmology. 247:42-60

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183952696.0x000001&indx=1&recIds=ETOCvdc_100183952696.0x000001

Chronic GvHD NIH Consensus Project Biology Task Force: evolving path to personalized treatment of chronic GvHD

Authors: Buxbaum, Nataliya P., Socié, Gerard, Hill, Geoffrey R., MacDonald, Kelli P. A., Tkachev, Victor, Teshima, Takanori, Lee, Stephanie J., Ritz, Jerome, Sarantopoulos, Stefanie, Luznik, Leo, Zeng, Defu, Paczesny, Sophie, Martin, Paul J., Pavletic, Steven Z., Schultz, Kirk R., Blazar, Bruce R.

Source: In Blood Advances 12 September 2023 7(17):4886-4902

Toward a Better Understanding of the Atypical Features of Chronic Graft-Versus-Host Disease: A Report from the 2020 National Institutes of Health Consensus Project Task Force

Authors: Cuvelier, Geoffrey D.E., Schoettler, Michelle, Buxbaum, Nataliya P., Pinal-Fernandez, Iago, Schmalzing, Marc, Distler, Jörg H.W., Penack, Olaf, Santomasso, Bianca D., Zeiser, Robert, Angstwurm, Klemens, MacDonald, Kelli P.A., Kimberly, W. Taylor, Taylor, Naomi, Bilic, Ervina, Banas, Bernhard, Buettner-Herold, Maike, Sinha, Namita, Greinix, Hildegard T., Pidala, Joseph, Schultz, Kirk R., Williams, Kirsten M., Inamoto, Yoshihiro, Cutler, Corey, Griffith, Linda M., Lee, Stephanie J., Sarantopoulos, Stefanie, Pavletic, Steven Z., Wolff, Daniel

Source: Transplantation and Cellular Therapy. 28(8):426-445

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169708893.0x000001&indx=1&recIds=ETOCvdc_100169708893.0x000001

National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2020 Highly morbid forms report

Authors: Wolff, Daniel, Radojcic, Vedran, Lafyatis, Robert, Cinar, Resat, Rosenstein, Rachel K., Cowen, Edward W., Cheng, Guang-Shing, Sheshadri, Ajay, Bergeron, Anne, Williams, Kirsten M., Todd, Jamie L., Teshima, Takanori, Cuvelier, Geoffrey D.E., Holler, Ernst, McCurdy, Shannon R., Jenq, Robert R., Hanash, Alan M., Jacobsohn, David, Santomasso, Bianca D., Jain, Sandeep, Ogawa, Yoko, Steven, Philipp, Luo, Zhonghui Katie, Dietrich-Ntoukas, Tina, Saban, Daniel, Bilic, Ervina, Penack, Olaf, Griffith, Linda M., Cowden, Meredith, Martin, Paul J., Greinix, Hildegard T., Sarantopoulos, Stefanie, Socie, Gerard, Blazar, Bruce R., Pidala, Joseph, Kitko, Carrie L., Couriel, Daniel R., Cutler, Corey, Schultz, Kirk R., Pavletic, Steven Z., Lee, Stephanie J., Paczesny, Sophie

Source: In Transplantation and Cellular Therapy October 2021 27(10):817-835

National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: III. The 2020 Treatment of Chronic GVHD Report

Authors: DeFilipp, Zachariah, Couriel, Daniel R., Lazaryan, Aleksandr, Bhatt, Vijaya Raj, Buxbaum, Nataliya P., Alousi, Amin M., Olivieri, Attilio, Pulanic, Drazen, Halter, Joerg P., Henderson, Lori A., Zeiser, Robert, Gooley, Ted A., MacDonald, Kelli P.A., Wolff, Daniel, Schultz, Kirk R., Paczesny, Sophie, Inamoto, Yoshihiro, Cutler, Corey S., Kitko, Carrie L., Pidala, Joseph A., Lee, Stephanie J., Socie, Gerard, Sarantopoulos, Stefanie, Pavletic, Steven Z., Martin, Paul J., Blazar, Bruce R., Greinix, Hildegard T.

Source: In Transplantation and Cellular Therapy September 2021 27(9):729-737

National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IIb. The 2020 Preemptive Therapy Working Group Report

Authors: Pidala, Joseph, Kitko, Carrie, Lee, Stephanie J., Carpenter, Paul, Cuvelier, Geoffrey D.E., Holtan, Shernan, Flowers, Mary E., Cutler, Corey, Jagasia, Madan, Gooley, Ted, Palmer, Joycelynne, Randolph, Tim, Levine, John E., Ayuk, Francis, Dignan, Fiona, Schoemans, Helene, Tkaczyk, Eric, Farhadfar, Nosha, Lawitschka, Anita, Schultz, Kirk R., Martin, Paul J., Sarantopoulos, Stefanie, Inamoto, Yoshihiro, Socie, Gerard, Wolff, Daniel, Blazar, Bruce, Greinix, Hildegard, Paczesny, Sophie, Pavletic, Steven, Hill, Geoffrey

Source: In Transplantation and Cellular Therapy August 2021 27(8):632-641

National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2020 Etiology and Prevention Working Group Report

Authors: Williams, Kirsten M., Inamoto, Yoshihiro, Im, Annie, Hamilton, Betty, Koreth, John, Arora, Mukta, Pusic, Iskra, Mays, Jacqueline W., Carpenter, Paul A., Luznik, Leo, Reddy, Pavan, Ritz, Jerome, Greinix, Hildegard, Paczesny, Sophie, Blazar, Bruce R., Pidala, Joseph, Cutler, Corey, Wolff, Daniel, Schultz, Kirk R., Pavletic, Steven Z., Lee, Stephanie J., Martin, Paul J., Socie, Gerard, Sarantopoulos, Stefanie

Source: In Transplantation and Cellular Therapy June 2021 27(6):452-466

BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation

Authors: Jia, Wei, Poe, Jonathan C., Su, Hsuan, Anand, Sarah, Matsushima, Glenn K., Rathmell, Jeffrey C., Maillard, Ivan, Radojcic, Vedran, Imai, Kazuhiro, Reyes, Nancy J., Cardona, Diana M., Li, Zhiguo, Suthers, Amy N., Curry-Chisolm, Itaevia M., DiCioccio, Rachel A., Saban, Daniel R., Chen, Benny J., Chao, Nelson J., Sarantopoulos, Stefanie ^*

Source: In Blood 6 May 2021 137(18):2544-2557

Exploring facilitators and barriers to daily chlorhexidine gluconate bathing in adult patients undergoing hematopoietic stem cell transplantation.

Authors: Artese, Ashley L., Sainvil, Michele, Fish, Laura J., Hill, Lauren, Somers, Tamara, Matthews, Anita, Blazek, Leah, Sito, Elizabeth, Andermann, Tessa, Rezvani, Andrew R., Choi, Taewoong, Gasparetto, Cristina J., Horwitz, Mitchell E., Long, Gwynn D., Lopez, Richard D., Rizzieri, David A., Sarantopoulos, Stefanie, Chao, Nelson J., Allen, Deborah H., Hong, Sanghee

Source: Supportive Care in Cancer; Dec2024, Vol. 32 Issue 12, p1-9, 9p

Clinical and Neuroimaging Correlates of Post-Transplant Delirium

Authors: Smith, Patrick, Thompson, Jillian C., Perea, Elena, Wasserman, Brian, Bohannon, Lauren, Racioppi, Alessandro, Choi, Taewoong, Gasparetto, Cristina, Horwitz, Mitchell E., Long, Gwynn, Lopez, Richard, Rizzieri, David A., Sarantopoulos, Stefanie, Sullivan, Keith M., Chao, Nelson J., Sung, Anthony D.

Source: In Biology of Blood and Marrow Transplantation December 2020 26(12):2323-2328

A Phase I Trial of SYK Inhibition with Fostamatinib in the Prevention and Treatment of Chronic Graft-Versus-Host Disease

Authors: Lin, Chenyu, DiCioccio, Rachel A., Haykal, Tarek, McManigle, William C., Li, Zhiguo, Anand, Sarah M., Poe, Jonathan C., Bracken, Sonali J., Jia, Wei, Alyea, Edwin P., Cardones, Adela R., Choi, Taewoong, Gasparetto, Cristina, Grunwald, Michael R., Hennig, Therese, Kang, Yubin, Long, Gwynn D., Lopez, Richard, Martin, Melissa, Minor, Kerry K., Quinones, Victor L. Perez, Sung, Anthony D., Wiggins, Kristi, Chao, Nelson J., Horwitz, Mitchell E., Rizzieri, David A., Sarantopoulos, Stefanie

Source: Transplantation and Cellular Therapy. 29(3):179.e1-179.e10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185415243.0x000001&indx=1&recIds=ETOCvdc_100185415243.0x000001

B cells in chronic graft-versus-host disease

Authors: McManigle, William, Youssef, Ayman, Sarantopoulos, Stefanie

Source: In Human Immunology June 2019 80(6):393-399

Autologous Hematopoietic Cell Transplantation for Treatment-Refractory Relapsing Multiple Sclerosis: Position Statement from the American Society for Blood and Marrow Transplantation

Authors: Cohen, Jeffrey A., Baldassari, Laura E., Atkins, Harold L., Bowen, James D., Bredeson, Christopher, Carpenter, Paul A., Corboy, John R., Freedman, Mark S., Griffith, Linda M., Lowsky, Robert, Majhail, Navneet S., Muraro, Paolo A., Nash, Richard A., Pasquini, Marcelo C., Sarantopoulos, Stefanie, Savani, Bipin N., Storek, Jan, Sullivan, Keith M., Georges, George E.

Source: In Biology of Blood and Marrow Transplantation May 2019 25(5):845-854

How I treat refractory chronic graft-versus-host disease

Authors: Sarantopoulos, Stefanie ^*, Cardones, Adela R., Sullivan, Keith M.

Source: In Blood 14 March 2019 133(11):1191-1200

Employment, Insurance, and Financial Experiences of Patients with Chronic Graft-versus-Host Disease in North America

Authors: Khera, Nandita, Hamilton, Betty K., Pidala, Joseph A., Wood, William A., Wu, Vicky, Voutsinas, Jenna, Onstad, Lynn, Alousi, Amin M., Broady, Raewyn, Chen, George L, Arora, Mukta, Cutler, Corey, Flowers, Mary E., Ganetsky, Alex, Jagasia, Madan, McCarthy, Philip L., Sarantopoulos, Stefanie, Abel, Gregory A., Majhail, Navneet S., Lee, Stephanie J.

Source: In Biology of Blood and Marrow Transplantation March 2019 25(3):599-605

Type II innate lymphoid cell plasticity contributes to impaired reconstitution after allogeneic hematopoietic stem cell transplantation.

Authors: Laurie, Sonia J., Foster II, Joseph P., Bruce, Danny W., Bommiasamy, Hemamalini, Kolupaev, Oleg V., Yazdimamaghani, Mostafa, Pattenden, Samantha G., Chao, Nelson J., Sarantopoulos, Stefanie, Parker, Joel S., Davis, Ian J., Serody, Jonathan S.

Source: Nature Communications; 7/17/2024, Vol. 15 Issue 1, p1-12, 12p

Subject Terms: HEMATOPOIETIC stem cell transplantation, INNATE lymphoid cells, T cells, HEMATOPOIETIC stem cells, MUCOUS membranes, GRAFT versus host disease, SMALL intestine, HOMEOSTASIS, IMMUNOPRECIPITATION

Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice

Authors: Radojcic, Vedran, Paz, Katelyn, Chung, Jooho, Du, Jing, Perkey, Eric T., Flynn, Ryan, Ivcevic, Sanja, Zaiken, Michael, Friedman, Ann, Yan, Minhong, Pletneva, Maria A., Sarantopoulos, Stefanie, Siebel, Christian W., Blazar, Bruce R. ^*, Maillard, Ivan

Source: In Blood 15 November 2018 132(20):2188-2200

Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD

Authors: Kolupaev, Oleg V., Dant, Trisha A., Bommiasamy, Hemamalini, Bruce, Danny W., Fowler, Kenneth A., Tilley, Stephen L., McKinnon, Karen P., Sarantopoulos, Stefanie, Blazar, Bruce R., Coghill, James M., Serody, Jonathan S.

Source: In Blood Advances 25 September 2018 2(18):2307-2319

Design and Patient Characteristics of the Chronic Graft-versus-Host Disease Response Measures Validation Study

Authors: Lee, Stephanie J. ^*, Hamilton, Betty K., Pidala, Joseph, Alousi, Amin, Kurukulasuriya, Chareeni, Onstad, Lynn, Jagasia, Madan, Chen, George, Cutler, Corey, Broady, Raewyn, Arora, Mukta, Arai, Sally, Sarantopoulos, Stefanie, Flowers, Mary E.

Source: In Biology of Blood and Marrow Transplantation August 2018 24(8):1727-1732