Inhibition of the LINE1-derived MET transcript induces apoptosis and oncoprotein knockdown in cancer cells

Authors: Miglio, Umberto ^{1, 8}, Berrino, Enrico ^{1, 2, 8}, Avanzato, Daniele ^{3, 6}, Molineris, Ivan ⁴, Miano, Valentina ^{5, 7}, Milan, Melissa ¹, Lanzetti, Letizia ^{1, 3}, Morelli, Eugenio ^{1, 3}, Hughes, James M. ¹, De Bortoli, Michele ⁵, Sapino, Anna ^{1, 2, 9}, Venesio, Tiziana ^{1, 9, ∗}

Source: In Molecular Therapy - Nucleic Acids 10 June 2025 36(2)

Parp-inhibitors in the therapeutic landscape of breast cancer patients with BRCA1 and BRCA2 pathogenic germline variants: An Italian consensus paper and critical review

Authors: Zambelli, Alberto, Cortesi, Laura, Gaudio, Mariangela, Arpino, Grazia, Bianchini, Giampaolo, Caruso, Francesco, Cinieri, Saverio, Curigliano, Giuseppe, Del Mastro, Lucia, De Placido, Sabino, Fabi, Alessandra, Fortunato, Lucio, Generali, Daniele, Gennari, Alessandra, Gori, Stefania, Grandi, Giovanni, Guarneri, Valentina, Klinger, Marco, Livi, Lorenzo, Marchiò, Caterina, Palumbo, Isabella, Panizza, Pietro, Pravettoni, Gabriella, Pruneri, Giancarlo, Puglisi, Fabio, Sapino, Anna, Tinterri, Corrado, Turchetti, Daniela, De Laurentiis, Michelino

Source: In Cancer Treatment Reviews November 2024 130

Post-surgery sequelae unrelated to disease progression and chemotherapy revealed in follow-up of patients with stage III colon cancer

Authors: Mirandola, Alexia, Kudriavtsev, Andrei, Cofre Muñoz, Catalina Isabel, Navarro, Raquel Comas, Macagno, Marco, Daoud, Saidi, Sanchez, Cynthia, Pastor, Brice, Pisareva, Ekaterina, Marin, Mireia Sanchis, Ruiz, Javier Gonzalo, Piris, Alejandro, Rodriguez, Ariadna Garcia, Gonzalez, Nadia Saoudi, Vivancos, Ana, Quarà, Virginia, Mellano, Alfredo, Borghi, Felice, Corti, Giorgio, Marchiò, Caterina, Sapino, Anna, Bartolini, Alice, Crisafulli, Giovanni, Bardelli, Alberto, Di Maio, Massimo, Lossaint, Gerald, Frayssinoux, Florence, Crapez, Evelyne, Ychou, Marc, Soler, Ramon Salazar, Fenocchio, Elisabetta, Fernandez Calotti, Paula X., Mazard, Thibault, Vivas, Cristina Santos, Elez, Elena, Di Nicolantonio, Federica, Thierry, Alain R.

Source: In eBioMedicine October 2024 108

CTC-derived pancreatic cancer models serve as research tools and are suitable for precision medicine approaches

Authors: Tang, Jiajia, Zheng, Quan, Wang, Qi, Zhao, Yaru, Ananthanarayanan, Preeta, Reina, Chiara, Šabanović, Berina, Jiang, Ke, Yang, Ming-Hsin, Meny, Clara Csilla, Wang, Huimin, Agerbaek, Mette Ø., Clausen, Thomas Mandel, Gustavsson, Tobias, Wen, Chenlei, Borghi, Felice, Mellano, Alfredo, Fenocchio, Elisabetta, Gregorc, Vanesa, Sapino, Anna, Theander, Thor G., Fu, Da, Aicher, Alexandra, Salanti, Ali, Shen, Baiyong, Heeschen, Christopher

Source: In Cell Reports Medicine 17 September 2024 5(9)

Loss of GABARAP mediates resistance to immunogenic chemotherapy in multiple myeloma

Authors: Gulla, Annamaria, Morelli, Eugenio, Johnstone, Megan, Turi, Marcello, Samur, Mehmet K., Botta, Cirino, Cifric, Selma, Folino, Pietro, Vinaixa, Delaney, Barello, Francesca, Clericuzio, Cole, Favasuli, Vanessa Katia, Maisano, Domenico, Talluri, Srikanth, Prabhala, Rao, Bianchi, Giada, Fulciniti, Mariateresa, Wen, Kenneth, Kurata, Keiji, Liu, Jiye, Penailillo, Johany, Bragoni, Alberto, Sapino, Anna, Richardson, Paul G., Chauhan, Dharminder, Carrasco, Ruben D., Hideshima, Teru, Munshi, Nikhil C., Anderson, Kenneth C.

Source: In Blood 20 June 2024 143(25):2612-2626

Alternative Tissue Fixation Protocols Dramatically Reduce the Impact of DNA Artifacts, Unraveling the Interpretation of Clinical Comprehensive Genomic Profiling

Authors: Berrino, Enrico, Bellomo, Sara Erika, Chesta, Anita, Detillo, Paolo, Bragoni, Alberto, Gagliardi, Amedeo, Naccarati, Alessio, Cereda, Matteo, Witel, Gianluca, Sapino, Anna, Bussolati, Benedetta, Bussolati, Gianni, Marchiò, Caterina

Source: In Laboratory Investigation January 2024 104(1)

Unique Patterns of Heterogeneous Mismatch Repair Protein Expression in Colorectal Cancer Unveil Different Degrees of Tumor Mutational Burden and Distinct Tumor Microenvironment Features

Authors: Berrino, Enrico, Aquilano, Maria Costanza, Valtorta, Emanuele, Amodio, Vito, Germano, Giovanni, Gusmini, Marco, Gizzi, Katiuscia, Fenocchio, Elisabetta, Sapino, Anna, Marsoni, Silvia, Sartore-Bianchi, Andrea, Bardelli, Alberto, Siena, Salvatore, Bonoldi, Emanuela, Marchiò, Caterina

Source: In Modern Pathology February 2023 36(2)

Growth Hormone-Releasing Hormone Antagonists Increase Radiosensitivity in Non-Small Cell Lung Cancer Cells.

Authors: Gesmundo, Iacopo, Pedrolli, Francesca, Giglioli, Francesca Romana, Jazaj, Florian, Granato, Giuseppina, Bertoldo, Alessia, Bistolfi, Federica, Gregorc, Vanesa, Sapino, Anna, Righi, Luisella, Cai, Renzhi, Sha, Wei, Wangpaichitr, Medhi, Papotti, Mauro, Ghigo, Ezio, Ricardi, Umberto, Schally, Andrew V., Granata, Riccarda

Source: International Journal of Molecular Sciences; Apr2025, Vol. 26 Issue 7, p3267, 19p

Subject Terms: NON-small-cell lung carcinoma, BCL-2 proteins, IONIZING radiation, CELL cycle, GENE expression

Biological and clinical features of triple negative Invasive Lobular Carcinomas of the breast. Clinical outcome and actionable molecular alterations

Authors: Conforti, Fabio, Pala, Laura, Pagan, Eleonora, Rocco, Elena Guerini, Bagnardi, Vincenzo, Montagna, Emilia, Peruzzotti, Giulia, De Pas, Tommaso, Fumagalli, Caterina, Pileggi, Silvana, Pesenti, Chiara, Marchini, Sergio, Corso, Giovanni, Marchio’, Caterina, Sapino, Anna, Graffeo, Rossella, Collet, Laetitia, Aftimos, Philippe, Sotiriou, Christos, Piccart, Martine, Gelber, Richard D., Viale, Giuseppe, Colleoni, Marco, Goldhirsch, Aron

Source: In The Breast October 2021 59:94-101

Evolving concepts in HER2 evaluation in breast cancer: Heterogeneity, HER2-low carcinomas and beyond

Authors: Marchiò, Caterina ^*, Annaratone, Laura, Marques, Ana, Casorzo, Laura, Berrino, Enrico, Sapino, Anna ^*

Source: In Seminars in Cancer Biology July 2021 72:123-135

Kinomic profiling of tumour xenografts derived from patients with non–small cell lung cancer confirms their fidelity and reveals potentially actionable pathways

Authors: Tabbò, Fabrizio, Guerrera, Francesco, van den Berg, Adrienne, Gaudiano, Marcello, Maletta, Francesca, Bessone, Luca, Nottegar, Alessia, Costardi, Lorena, de Wijn, Rik, Ruijtenbeek, Rob, Delsedime, Luisa, Sapino, Anna, Ruffini, Enrico, Hilhorst, Riet, Inghirami, Giorgio

Source: In European Journal of Cancer February 2021 144:17-30

Reoperation rate after breast conserving surgery as quality indicator in breast cancer treatment: A reappraisal

Authors: Tamburelli, Francesca, Maggiorotto, Furio, Marchiò, Caterina, Balmativola, Davide, Magistris, Alessandra, Kubatzki, Franziska, Sgandurra, Paola, Di Virgilio, Maria Rosaria, Regge, Daniele, Montemurro, Filippo, Gatti, Marco, Sapino, Anna, Ponzone, Riccardo

Source: In The Breast October 2020 53:181-188

The requirements of a specialist breast centre

Authors: Biganzoli, Laura, Cardoso, Fatima, Beishon, Marc, Cameron, David, Cataliotti, Luigi, Coles, Charlotte E., Delgado Bolton, Roberto C., Trill, Maria Die, Erdem, Sema, Fjell, Maria, Geiss, Romain, Goossens, Mathijs, Kuhl, Christiane, Marotti, Lorenza, Naredi, Peter, Oberst, Simon, Palussière, Jean, Ponti, Antonio, Rosselli Del Turco, Marco, Rubio, Isabel T., Sapino, Anna, Senkus-Konefka, Elzbieta, Skelin, Marko, Sousa, Berta, Saarto, Tiina, Costa, Alberto, Poortmans, Philip

Source: In The Breast June 2020 51:65-84

120 Compendium of Homologous Recombination Alterations in High-Risk Breast Carcinomas

Authors: Bellomo, Sara Erika ¹, Berrino, Enrico ¹, Sapino, Anna ², Marchio, Caterina ³

Source: In Laboratory Investigation March 2025 105(3) Supplement

MiR-100 is a predictor of endocrine responsiveness and prognosis in patients with operable luminal breast cancer

Authors: Petrelli, Annalisa, Bellomo, Sara Erika, Sarotto, Ivana, Kubatzki, Franziska, Sgandurra, Paola, Maggiorotto, Furio, Di Virgilio, Maria Rosaria, Ponzone, Riccardo, Geuna, Elena, Galizia, Danilo, Nuzzo, Anna Maria, Medico, Enzo, Miglio, Umberto, Berrino, Enrico, Venesio, Tiziana, Ribisi, Salvatore, Provero, Paolo, Sapino, Anna, Giordano, Silvia, Montemurro, Filippo

Source: In ESMO Open 2020 5(5)

Pertuzumab and trastuzumab emtansine in patients with HER2-amplified metastatic colorectal cancer: the phase II HERACLES-B trial

Authors: Sartore-Bianchi, Andrea, Lonardi, Sara, Martino, Cosimo, Fenocchio, Elisabetta, Tosi, Federica, Ghezzi, Silvia, Leone, Francesco, Bergamo, Francesca, Zagonel, Vittorina, Ciardiello, Fortunato, Ardizzoni, Andrea, Amatu, Alessio, Bencardino, Katia, Valtorta, Emanuele, Grassi, Elena, Torri, Valter, Bonoldi, Emanuela, Sapino, Anna, Vanzulli, Angelo, Regge, Daniele, Cappello, Giovanni, Bardelli, Alberto, Trusolino, Livio, Marsoni, Silvia, Siena, Salvatore

Source: In ESMO Open 2020 5(5)

Recommendations for the implementation of BRCA testing in ovarian cancer patients and their relatives

Authors: Gori, Stefania, Barberis, Massimo, Bella, Maria Angela, Buttitta, Fiamma, Capoluongo, Ettore, Carrera, Paola, Colombo, Nicoletta, Cortesi, Laura, Genuardi, Maurizio, Gion, Massimo, Guarneri, Valentina, Incorvaia, Lorena, La Verde, Nicla, Lorusso, Domenica, Marchetti, Antonio, Marchetti, Paolo, Normanno, Nicola, Pasini, Barbara, Pensabene, Matilde, Pignata, Sandro, Radice, Paolo, Ricevuto, Enrico, Sapino, Anna, Tagliaferri, Pierosandro, Tassone, Pierfrancesco, Trevisiol, Chiara, Truini, Mauro, Varesco, Liliana, Russo, Antonio

Source: In Critical Reviews in Oncology / Hematology August 2019 140:67-72

Monitoring circulating tumor DNA liquid biopsy in stage III BRAF-mutant melanoma patients undergoing adjuvant treatment.

Authors: Marchisio, Sara, Ricci, Alessia Andrea, Roccuzzo, Gabriele, Bongiovanni, Eleonora, Ortolan, Erika, Bertero, Luca, Berrino, Enrico, Pala, Valentina, Ponti, Renata, Fava, Paolo, Osella-Abate, Simona, Deaglio, Silvia, Marchiò, Caterina, Sapino, Anna, Senetta, Rebecca, Funaro, Ada, Ribero, Simone, Quaglino, Pietro, Cassoni, Paola

Source: Journal of Translational Medicine; 11/28/2024, Vol. 22 Issue 1, p1-11, 11p

Subject Terms: CIRCULATING tumor DNA, DISEASE relapse, OVERALL survival, SKIN diseases, PATIENT monitoring

Gasdermin C promotes Stemness and Immune Evasion in Pancreatic Cancer via Pyroptosis‐Independent Mechanism.

Authors: Wu, Renfei, Li, Jingwei, Aicher, Alexandra, Jiang, Ke, Tondi, Serena, Dong, Shuang, Zheng, Quan, Tang, Siqi, Chen, Minchun, Guo, Zhenyang, Šabanović, Berina, Ananthanarayanan, Preeta, Jiang, Lingxi, Sapino, Anna, Wen, Chenlei, Fu, Da, Shen, Baiyong, Heeschen, Christopher

Source: Advanced Science; 11/13/2024, Vol. 11 Issue 42, p1-24, 24p

Subject Terms: CANCER stem cells, PANCREATIC duct, PROMOTERS (Genetics), RESPONSE inhibition, CELL death

Dataset for reporting of the invasive carcinoma of the breast: recommendations from the International Collaboration on Cancer Reporting (ICCR).

Authors: Ellis, Ian, Webster, Fleur, Allison, Kimberly H, Dang, Chau, Gobbi, Helenice, Kulka, Janina, Lakhani, Sunil R, Moriya, Takuya, Quinn, Cecily M, Sapino, Anna, Schnitt, Stuart, Sibbering, D Mark, Slodkowska, Elzbieta, Yang, Wentao, Tan, Puay H

Source: Histopathology; Sep2024, Vol. 85 Issue 3, p418-436, 19p

Subject Terms: CANCER invasiveness, BREAST cancer, CANCER patients, PATHOLOGISTS, PATHOLOGY, BREAST