Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques

Authors: Saunders, Kevin O., Counts, James, Thakur, Bhishem, Stalls, Victoria, Edwards, Robert, Manne, Kartik, Lu, Xiaozhi, Mansouri, Katayoun, Chen, Yue, Parks, Rob, Barr, Maggie, Sutherland, Laura, Bal, Joena, Havill, Nicholas, Chen, Haiyan, Machiele, Emily, Jamieson, Nolan, Hora, Bhavna, Kopp, Megan, Janowska, Katarzyna, Anasti, Kara, Jiang, Chuancang, Van Itallie, Elizabeth, Venkatayogi, Sravani, Eaton, Amanda, Henderson, Rory, Barbosa, Christopher, Alam, S. Munir, Santra, Sampa, Weissman, Drew, Moody, M. Anthony, Cain, Derek W., Tam, Ying K., Lewis, Mark, Williams, Wilton B., Wiehe, Kevin, Montefiori, David C., Acharya, Priyamvada, Haynes, Barton F.

Source: In Cell 4 January 2024 187(1):79-94

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

Authors: Williams, Wilton B., Meyerhoff, R. Ryan, Edwards, R.J., Li, Hui, Manne, Kartik, Nicely, Nathan I., Henderson, Rory, Zhou, Ye, Janowska, Katarzyna, Mansouri, Katayoun, Gobeil, Sophie, Evangelous, Tyler, Hora, Bhavna, Berry, Madison, Abuahmad, A. Yousef, Sprenz, Jordan, Deyton, Margaret, Stalls, Victoria, Kopp, Megan, Hsu, Allen L., Borgnia, Mario J., Stewart-Jones, Guillaume B.E., Lee, Matthew S., Bronkema, Naomi, Moody, M. Anthony, Wiehe, Kevin, Bradley, Todd, Alam, S. Munir, Parks, Robert J., Foulger, Andrew, Oguin, Thomas, Sempowski, Gregory D., Bonsignori, Mattia, LaBranche, Celia C., Montefiori, David C., Seaman, Michael, Santra, Sampa, Perfect, John, Francica, Joseph R., Lynn, Geoffrey M., Aussedat, Baptiste, Walkowicz, William E., Laga, Richard, Kelsoe, Garnett, Saunders, Kevin O., Fera, Daniela, Kwong, Peter D., Seder, Robert A., Bartesaghi, Alberto, Shaw, George M., Acharya, Priyamvada, Haynes, Barton F.

Source: In Cell 27 May 2021 184(11):2955-2972

Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization

Authors: Han, Qifeng, Bradley, Todd, Williams, Wilton B., Cain, Derek W., Montefiori, David C., Saunders, Kevin O., Parks, Robert J., Edwards, Regina W., Ferrari, Guido, Mueller, Olaf, Shen, Xiaoying, Wiehe, Kevin J., Reed, Steven, Fox, Christopher B., Rountree, Wes, Vandergrift, Nathan A., Wang, Yunfei, Sutherland, Laura L., Santra, Sampa, Moody, M. Anthony, Permar, Sallie R., Tomaras, Georgia D., Lewis, Mark G., Van Rompay, Koen K.A., Haynes, Barton F.

Source: In Cell Reports 4 February 2020 30(5):1553-1569

Recombinant Poxvirus Boosting of DNA-Primed Rhesus Monkeys Augments Peak but Not Memory T Lymphocyte Responses

Authors: Santra, Sampa, Barouch, Dan H., Korioth-Schmitz, Birgit, Lord, Carol I., Krivulka, Georgia R., Yu, Faye, Beddall, Margaret H., Gorgone, Darci A., Lifton, Michelle A., Miura, Ayako, Philippon, Valerie, Manson, Kelledy, Markham, Phillip D., Parrish, John, Kuroda, Marcelo J., Schmitz, Jörn E., Gelman, Rebecca S., Shiver, John W., Montefiori, David C., Panicali, Dennis, Letvin, Norman L., Palese, Peter

Source: Proceedings of the National Academy of Sciences of the United States of America, 2004 Jul . 101(30), 11088-11093.

Access URL: https://www.jstor.org/stable/3372857

Control of Viremia and Prevention of Clinical AIDS in Rhesus Monkeys by Cytokine-Augmented DNA Vaccination

Authors: Barouch, Dan H., Santra, Sampa, Schmitz, Jörn E., Kuroda, Marcelo J., Fu, Tong-Ming, Wagner, Wendeline, Bilska, Miroslawa, Craiu, Abie, Zheng, Xin Xiao, Krivulka, Georgia R., Beaudry, Kristin, Lifton, Michelle A., Nickerson, Christine E., Trigona, Wendy L., Punt, Kara, Freed, Dan C., Guan, Liming, Dubey, Sheri, Casimiro, Danilo, Simon, Adam, Davies, Mary-Ellen, Chastain, Michael, Strom, Terry B., Gelman, Rebecca S., Montefiori, David C., Lewis, Mark G., Emini, Emilio A., Shiver, John W., Letvin, Norman L.

Source: Science, 2000 Oct . 290(5491), 486-492.

Access URL: https://www.jstor.org/stable/3078019

Augmentation of Immune Responses to HIV-1 and Simian Immunodeficiency Virus DNA Vaccines by IL-2/Ig Plasmid Administration in Rhesus Monkeys

Authors: Barouch, Dan H., Craiu, Abie, Kuroda, Marcelo J., Schmitz, Jorn E., Zheng, Xin Xiao, Santra, Sampa, Frost, Julie D., Krivulka, Georgia R., Lifton, Michelle A., Crabbs, Carroll L., Heidecker, Gwendolyn, Perry, Helen C., Davies, Mary-Ellen, Xie, Hong, Nickerson, Christine E., Steenbeke, Tavis D., Lord, Carol I., Montefiori, David C., Strom, Terry B., Shiver, John W., Lewis, Mark G., Letvin, Norman L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2000 Apr 01. 97(8), 4192-4197.

Access URL: https://www.jstor.org/stable/122131

Control of Viremia in Simian Immunodeficiency Virus Infection by CD8$^+$ Lymphocytes

Authors: Schmitz, Jörn E., Kuroda, Marcelo J., Santra, Sampa, Sasseville, Vito G., Simon, Meredith A., Lifton, Michelle A., Racz, Paul, Tenner-Racz, Klara, Dalesandro, Margaret, Scallon, Bernhard J., Ghrayeb, John, Forman, Meryl A., Montefiori, David C., Rieber, E. Peter, Letvin, Norman L., Reimann, Keith A.

Source: Science, 1999 Feb 01. 283(5403), 857-860.

Access URL: https://www.jstor.org/stable/2897254

A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge

Authors: Madani, Navid, Princiotto, Amy, Mach, Linh, Ding, Shilei, Prevost, Jérémie, Richard, Jonathan, Hora, Bhavna, Sutherland, Laura, Zhao, Connie, Conn, Brandon, Bradley, Todd, Moody, M., Melillo, Bruno, Finzi, Andrés, Haynes, Barton, Smith III, Amos, Santra, Sampa, Sodroski, Joseph

Source: Nature communications. 9(1):1-9

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100170089409.0x000001&indx=1&recIds=ETOCvdc_100170089409.0x000001

IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells

Authors: Blasi, Maria, Negri, Donatella, LaBranche, Celia, Alam, S., Baker, Erich, Brunner, Elizabeth, Gladden, Morgan, Michelini, Zuleika, Vandergrift, Nathan, Wiehe, Kevin, Parks, Robert, Shen, Xiaoying, Bonsignori, Mattia, Tomaras, Georgia, Ferrari, Guido, Montefiori, David, Santra, Sampa, Haynes, Barton, Moody, Michael, Cara, Andrea, Klotman, Mary

Source: Communications biology. 1(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179708135.0x000001&indx=1&recIds=ETOCvdc_100179708135.0x000001

Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection

Authors: Astronomo, Rena D., Santra, Sampa, Ballweber-Fleming, Lamar, Westerberg, Katharine G., Mach, Linh, Hensley-McBain, Tiffany, Sutherland, Laura, Mildenberg, Benjamin, Morton, Georgeanna, Yates, Nicole L., Mize, Gregory J., Pollara, Justin, Hladik, Florian, Ochsenbauer, Christina, Denny, Thomas N., Warrier, Ranjit, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayapan, Sorachai, Kaewkungwal, Jaranit, Ferrari, Guido, Shaw, George M., Xia, Shi-Mao, Liao, Hua-Xin, Montefiori, David C., Tomaras, Georgia D., Haynes, Barton F., McElrath, M. Juliana

Source: In EBioMedicine December 2016 14:97-111

Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques

Authors: Negri, Donatella, Blasi, Maria, LaBranche, Celia, Parks, Robert, Balachandran, Harikrishnan, Lifton, Michelle, Shen, Xiaoying, Denny, Thomas, Ferrari, Guido, Vescio, Maria Fenicia, Andersen, Hanne, Montefiori, David C, Tomaras, Georgia D, Liao, Hua-Xin, Santra, Sampa, Haynes, Barton F, Klotman, Mary E, Cara, Andrea

Source: In Molecular Therapy November 2016 24(11):2021-2032

Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity

Authors: Bradley, Todd, Trama, Ashley, Tumba, Nancy, Gray, Elin, Lu, Xiaozhi, Madani, Navid, Jahanbakhsh, Fatemeh, Eaton, Amanda, Xia, Shi-Mao, Parks, Robert, Lloyd, Krissey E., Sutherland, Laura L., Scearce, Richard M., Bowman, Cindy M., Barnett, Susan, Abdool-Karim, Salim S., Boyd, Scott D., Melillo, Bruno, Smith, Amos B., III, Sodroski, Joseph, Kepler, Thomas B., Alam, S.Munir, Gao, Feng, Bonsignori, Mattia, Liao, Hua-Xin, Moody, M. Anthony, Montefiori, David, Santra, Sampa, Morris, Lynn, Haynes, Barton F.

Source: In EBioMedicine October 2016 12:196-207

Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques

Authors: Li, Hui, Wang, Shuyi, Kong, Rui, Ding, Wenge, Lee, Fang-Hua, Parker, Zahra, Kim, Eunlim, Learn, Gerald H., Hahn, Paul, Policicchio, Ben, Brocca-Cofano, Egidio, Deleage, Claire, Hao, Xingpei, Chuang, Gwo-Yu, Gorman, Jason, Gardner, Matthew, Lewis, Mark G., Hatziioannou, Theodora, Santra, Sampa, Apetrei, Cristian, Pandrea, Ivona, Alam, S. Munir, Liao, Hua-Xin, Shen, Xiaoying, Tomaras, Georgia D., Farzan, Michael, Chertova, Elena, Keele, Brandon F., Estes, Jacob D., Lifson, Jeffrey D., Doms, Robert W., Montefiori, David C., Haynes, Barton F., Sodroski, Joseph G., Kwong, Peter D., Hahn, Beatrice H., Shaw, George M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2016 Jun . 113(24), E3413-E3422.

Access URL: https://www.jstor.org/stable/26470309

Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site

Authors: Bradley, Todd, Fera, Daniela, Bhiman, Jinal, Eslamizar, Leila, Lu, Xiaozhi, Anasti, Kara, Zhang, Ruijung, Sutherland, Laura L., Scearce, Richard M., Bowman, Cindy M., Stolarchuk, Christina, Lloyd, Krissey E., Parks, Robert, Eaton, Amanda, Foulger, Andrew, Nie, Xiaoyan, Karim, Salim S. Abdool, Barnett, Susan, Kelsoe, Garnett, Kepler, Thomas B., Alam, S. Munir, Montefiori, David C., Moody, M. Anthony, Liao, Hua-Xin, Morris, Lynn, Santra, Sampa, Harrison, Stephen C., Haynes, Barton F.

Source: In Cell Reports 5 January 2016 14(1):43-54

D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

Authors: Weissman, Drew, Alameh, Mohamad-Gabriel, de Silva, Thushan, Collini, Paul, Hornsby, Hailey, Brown, Rebecca, LaBranche, Celia C., Edwards, Robert J., Sutherland, Laura, Santra, Sampa, Mansouri, Katayoun, Gobeil, Sophie, McDanal, Charlene, Pardi, Norbert, Hengartner, Nick, Lin, Paulo J.C., Tam, Ying, Shaw, Pamela A., Lewis, Mark G., Boesler, Carsten, Şahin, Uğur, Acharya, Priyamvada, Haynes, Barton F., Korber, Bette, Montefiori, David C.

Source: Cell host & microbe. 29(1):23-31.e4

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135755429.0x000001&indx=1&recIds=ETOCvdc_100135755429.0x000001

Recombinant MVA-prime elicits neutralizing antibody responses by inducing antigen-specific B cells in the germinal center

Authors: Eslamizar, Leila, Petrovas, Constantinos, Leggat, David J., Furr, Kathryn, Lifton, Michelle L., Levine, Gail, Ma, Steven, Fletez-Brant, Christopher, Hoyland, Wesley, Prabhakaran, Madhu, Narpala, Sandeep, Boswell, Kristin, Yamamoto, Takuya, Liao, Hua-Xin, Pickup, David, Ramsburg, Elizabeth, Sutherland, Laura, McDermott, Adrian, Roederer, Mario, Montefiori, David, Koup, Richard A., Haynes, Barton F., Letvin, Norman L., Santra, Sampa

Source: Npj vaccines. 6(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193131200.0x000001&indx=1&recIds=ETOCvdc_100193131200.0x000001

Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates

Authors: Saunders, Kevin O., Nicely, Nathan I., Wiehe, Kevin, Bonsignori, Mattia, Meyerhoff, R. Ryan, Parks, Robert, Walkowicz, William E., Aussedat, Baptiste, Wu, Nelson R., Cai, Fangping, Vohra, Yusuf, Park, Peter K., Eaton, Amanda, Go, Eden P., Sutherland, Laura L., Scearce, Richard M., Barouch, Dan H., Zhang, Ruijun, Von Holle, Tarra, Overman, R. Glenn, Anasti, Kara, Sanders, Rogier W., Moody, M. Anthony, Kepler, Thomas B., Korber, Bette, Desaire, Heather, Santra, Sampa, Letvin, Norman L., Nabel, Gary J., Montefiori, David C., Tomaras, Georgia D., Liao, Hua-Xin, Alam, S. Munir, Danishefsky, Samuel J., Haynes, Barton F.

Source: Cell reports. 18(9):2175-2188

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100061868381.0x000001&indx=1&recIds=ETOCvdc_100061868381.0x000001

Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models

Authors: Saunders, Kevin O., Verkoczy, Laurent K., Jiang, Chuancang, Zhang, Jinsong, Parks, Robert, Chen, Haiyan, Housman, Max, Bouton-Verville, Hilary, Shen, Xiaoying, Trama, Ashley M., Scearce, Richard, Sutherland, Laura, Santra, Sampa, Newman, Amanda, Eaton, Amanda, Xu, Kai, Georgiev, Ivelin S., Joyce, M. Gordon, Tomaras, Georgia D., Bonsignori, Mattia, Reed, Steven G., Salazar, Andres, Mascola, John R., Moody, M. Anthony, Cain, Derek W., Centlivre, Mireille, Zurawski, Sandra, Zurawski, Gerard, Erickson, Harold P., Kwong, Peter D., Alam, S. Munir, Levy, Yves, Montefiori, David C., Haynes, Barton F.

Source: Cell reports. 21(13):3681-3690

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100056942114.0x000001&indx=1&recIds=ETOCvdc_100056942114.0x000001

Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes

Authors: Asmal, Mohammed, Luedemann, Corinne, Lavine, Christy L., Mach, Linh V., Balachandran, Harikrishnan, Brinkley, Christie, Denny, Thomas N., Lewis, Mark G., Anderson, Hanne, Pal, Ranajit, Sok, Devin, Le, Khoa, Pauthner, Matthias, Hahn, Beatrice H., Shaw, George M., Seaman, Michael S., Letvin, Norman L., Burton, Dennis R., Sodroski, Joseph G., Haynes, Barton F., Santra, Sampa

Source: In Virology 15 January 2015 475:37-45

Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved

Authors: Wiehe, Kevin, Easterhoff, David, Luo, Kan, Nicely, Nathan I., Bradley, Todd, Jaeger, Frederick H., Dennison, S. Moses, Zhang, Ruijun, Lloyd, Krissey E., Stolarchuk, Christina, Parks, Robert, Sutherland, Laura L., Scearce, Richard M., Morris, Lynn, Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Sinangil, Faruk, Phogat, Sanjay, Michael, Nelson L., Kim, Jerome H., Kelsoe, Garnett, Montefiori, David C., Tomaras, Georgia D., Bonsignori, Mattia, Santra, Sampa, Kepler, Thomas B., Alam, S. Munir, Moody, M. Anthony, Liao, Hua-Xin, Haynes, Barton F.

Source: In Immunity 18 December 2014 41(6):909-918