Durvalumab with or without bevacizumab with transarterial chemoembolisation in hepatocellular carcinoma (EMERALD-1): a multiregional, randomised, double-blind, placebo-controlled, phase 3 study

Authors: Abdalla, Kathia, Allaire, Manon, Alves, Gustavo, Antunes, Luis, Assenat, Eric, Azevedo, Sergio, Barreto, Rafael, Beg, Muhammad, Bertollo, Glaucio, Blanc, Jean-Frederic, Bouattour, Mohamed, Boya, Rakesh Reddy, Breder, Valery, Bronowicki, Jean-Pierre, Buranachokphaisan, Manoch, Burgoyne, Adam, Chan, Stephen, Chang, Ting-Tsung, Chao, Yee, Chen, Eric, Chen, Xiaoming, Chiu, Chang-Fang, Choi, Minsig, Choi, Sunghee, Coburn, Natalie, Contreras, Luis, Dayyani, Farshid, Decaens, Thomas, Dechaphunkul, Arunee, del Consuelo Diaz, Maria, Dev, Anouk, Dutra, Jamille, Eastgate, Melissa, Escobar, Jose, Estfan, Bassam, Ferrari, Vittorio, Frin, Anne-Claire, Ganguly, Sandip, Ganta, Ranga Raman, Gu, Shanzhi, Guo, Yabing, Hagihara, Atsushi, Heo, Jeong, Hsu, Chih-Hung, Hwang, Jimmy, Inaba, Yoshitaka, Jain, Shikha, Jonker, Derek, K, Rajeev L, Kate, Shruti, Kato, Naoya, Kawaoka, Tomokazu, Kee, Kwong-Ming, Kim, Seung up, Kioka, Kiyohide, Koga, Hironori, Kudo, Masatoshi, Kuroda, Hidekatsu, Le, Phuong, Lee, Han-chu, Lee, Joon Hyeok, Lee, Teng-Yu, Li, Dongliang, Li, Hailiang, Li, Wei, Li, Xiao, Lin, Cheng-Yao, Lin, Shi-Ming, Lopez, Yamil, Lu, Ligong, Mai, Anh, Mamontov, Konstantin, Maneenil, Kunlatida, Manikhas, Aleksei, Masi, Gianluca, Matilla, Ana Maria, Matos, Marco, Mazzaferro, Vincenzo, Meng, Zhiqiang, Mohapatra, Prabrajya Narayan, Moiseyenko, Vladimir, Molina, Alejandro, Montero, Jose Luis, Morimoto, Manabu, Motola, Daniel, Mukhametshina, Guzel, Nakagawa, Hayato, Nault, Jean-Charles, Nguyen, Quang, Nicoll, Amanda, Noriega, Maria, Okusaka, Takuji, Onishi, Hideki, Ostwal, Vikas Sureshchand, Pan, Jie, Park, Joong-Won, Patel, Ankit, Perez, Rodrigo, Peron, Jean-Marie, Qin, Shukui, Ramirez, Francisco, Ren, Zhenggang, Roberts, Stuart, Rowe, Julie, Runglodvatana, Yotsawaj, Sangro, Bruno, Santos, Florinda, Saxena, Ravi Kumar, Shao, Guoliang, Shields, Anthony, Shirokova, Oksana, Shreenivas, Aditya, Sisani, Michele, Skoropad, Vitalii, Strasser, Simone, Suksombooncharoen, Thatthan, Suttichaimongkol, Tanita, Tai, Wai Meng, Tak, Won Young, Teng, Gaojun, Thungappa, Satheesh Chiradoni, Tran, Nguyen, Trinh, Son, Tsuchiya, Kaoru, Tsuji, Kunihiko, Ugarteburu, Idoia, Ungtrakul, Teerapat, Vaccaro, Gina, Veluvolu, Anil, Vo, Truc, Wada, Yoshiyuki, Weir, Alva, Xu, Aibing, Yan, Lvnan, Yoon, Jung-Hwan, Zarubenkov, Oleg, Zeng, Yongyi, Zhang, Yonghong, Zhao, Ming, Zheng, Xin, Zhu, Ling, Zhu, Xu, Erinjeri, Joseph P ^c, Chan, Stephen L ^f, Arai, Yasuaki ^g, Lopez Chuken, Yamil Alonso ^k, Breder, Valeriy V ⁿ, Nguyen, Quang T ^s, Yan, Lunan ^t, Santos, Florinda A ^v, Żotkiewicz, Magdalena ^z, Udoye, Stephanie I ^aa, Kurland, John F ^aa, Cohen, Gordon J ^aa, Lencioni, Riccardo ^ab

Source: In The Lancet 18-24 January 2025 405(10474):216-232

Durvalumab with or without bevacizumab with transarterial chemoembolisation in hepatocellular carcinoma (EMERALD-1): a multiregional, randomised, double-blind, placebo-controlled, phase 3 study

Authors: Sangro, Bruno, Kudo, Masatoshi, Erinjeri, Joseph P, Qin, Shukui, Ren, Zhenggang, Chan, Stephen L, Arai, Yasuaki, Heo, Jeong, Mai, Anh, Escobar, Jose, Lopez Chuken, Yamil Alonso, Yoon, Jung-Hwan, Tak, Won Young, Breder, Valeriy V, Suttichaimongkol, Tanita, Bouattour, Mohamed, Lin, Shi-Ming, Peron, Jean-Marie, Nguyen, Quang T, Yan, Lunan, Chiu, Chang-Fang, Santos, Florinda A, Veluvolu, Anil, Thungappa, Satheesh Chiradoni, Matos, Marco, Żotkiewicz, Magdalena, Udoye, Stephanie I, Kurland, John F, Cohen, Gordon J, Lencioni, Riccardo, Abdalla, Kathia, Allaire, Manon, Alves, Gustavo, Antunes, Luis, Assenat, Eric, Azevedo, Sergio, Barreto, Rafael, Beg, Muhammad, Bertollo, Glaucio, Blanc, Jean-Frederic, Bouattour, Mohamed, Boya, Rakesh Reddy, Breder, Valery, Bronowicki, Jean-Pierre, Buranachokphaisan, Manoch, Burgoyne, Adam, Chan, Stephen, Chang, Ting-Tsung, Chao, Yee, Chen, Eric, Chen, Xiaoming, Chiu, Chang-Fang, Choi, Minsig, Choi, Sunghee, Coburn, Natalie, Contreras, Luis, Dayyani, Farshid, Decaens, Thomas, Dechaphunkul, Arunee, del Consuelo Diaz, Maria, Dev, Anouk, Dutra, Jamille, Eastgate, Melissa, Escobar, Jose, Estfan, Bassam, Ferrari, Vittorio, Frin, Anne-Claire, Ganguly, Sandip, Ganta, Ranga Raman, Gu, Shanzhi, Guo, Yabing, Hagihara, Atsushi, Heo, Jeong, Hsu, Chih-Hung, Hwang, Jimmy, Inaba, Yoshitaka, Jain, Shikha, Jonker, Derek, K, Rajeev L, Kate, Shruti, Kato, Naoya, Kawaoka, Tomokazu, Kee, Kwong-Ming, Kim, Seung up, Kioka, Kiyohide, Koga, Hironori, Kudo, Masatoshi, Kuroda, Hidekatsu, Le, Phuong, Lee, Han-chu, Lee, Joon Hyeok, Lee, Teng-Yu, Li, Dongliang, Li, Hailiang, Li, Wei, Li, Xiao, Lin, Cheng-Yao, Lin, Shi-Ming, Lopez, Yamil, Lu, Ligong, Mai, Anh, Mamontov, Konstantin, Maneenil, Kunlatida, Manikhas, Aleksei, Masi, Gianluca, Matilla, Ana Maria, Matos, Marco, Mazzaferro, Vincenzo, Meng, Zhiqiang, Mohapatra, Prabrajya Narayan, Moiseyenko, Vladimir, Molina, Alejandro, Montero, Jose Luis, Morimoto, Manabu, Motola, Daniel, Mukhametshina, Guzel, Nakagawa, Hayato, Nault, Jean-Charles, Nguyen, Quang, Nicoll, Amanda, Noriega, Maria, Okusaka, Takuji, Onishi, Hideki, Ostwal, Vikas Sureshchand, Pan, Jie, Park, Joong-Won, Patel, Ankit, Perez, Rodrigo, Peron, Jean-Marie, Qin, Shukui, Ramirez, Francisco, Ren, Zhenggang, Roberts, Stuart, Rowe, Julie, Runglodvatana, Yotsawaj, Sangro, Bruno, Santos, Florinda, Saxena, Ravi Kumar, Shao, Guoliang, Shields, Anthony, Shirokova, Oksana, Shreenivas, Aditya, Sisani, Michele, Skoropad, Vitalii, Strasser, Simone, Suksombooncharoen, Thatthan, Suttichaimongkol, Tanita, Tai, Wai Meng, Tak, Won Young, Teng, Gaojun, Thungappa, Satheesh Chiradoni, Tran, Nguyen, Trinh, Son, Tsuchiya, Kaoru, Tsuji, Kunihiko, Ugarteburu, Idoia, Ungtrakul, Teerapat, Vaccaro, Gina, Veluvolu, Anil, Vo, Truc, Wada, Yoshiyuki, Weir, Alva, Xu, Aibing, Yan, Lvnan, Yoon, Jung-Hwan, Zarubenkov, Oleg, Zeng, Yongyi, Zhang, Yonghong, Zhao, Ming, Zheng, Xin, Zhu, Ling, Zhu, Xu

Source: The Lancet; January 2025, Vol. 405 Issue: 10474 p216-232, 17p

Metformin plus lrinotecan in patients with refractory colorectal cancer: a phase 2 clinical trial

Authors: Bragagnoli, Arinilda Campos, Araujo, Raphael L. C., Ferraz, Mauricio Wagner, Santos, Lucas Vieirados, Abdalla, Kathia Cristina, Comar, Fabiana, Santos, Florinda Almeida, Oliveira, Marco Antonio, Carvalheira, José Barreto Campello, Cárcano, Flávio Mavigner

Source: British journal of cancer. 124(6):1072-1078

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626477730&indx=1&recIds=ETOCRN626477730

Plasma mutation profile of precursor lesions and colorectal cancer using the Oncomine Colon cfDNA Assay.

Authors: dos Reis, Mariana Bisarro, dos Santos, Wellington, de Carvalho, Ana Carolina, Lima, Adhara Brandão, Reis, Monise Tadin, Santos, Florinda, Reis, Rui Manuel, Guimarães, Denise Peixoto

Source: BMC Cancer; 12/18/2024, Vol. 24 Issue 1, p1-11, 11p

Subject Terms: MEDICAL sciences, GENETIC variation, RAS oncogenes, CIRCULATING tumor DNA, CELL-free DNA, TUMOR markers

Safety analysis by treatment periods from EMERALD-1: A phase 3, randomized, placebo-controlled study of transarterial chemoembolization with durvalumab with/without bevacizumab in participants with embolization-eligible unresectable hepatocellular...

Authors: Kudo, Masatoshi, Chan, Stephen Lam, Sangro, Bruno, Erinjeri, Joseph P., Qin, Shukui, Ren, Zhenggang, Arai, Yasuaki, Breder, Valeriy Vladimirovich, Lin, Shi-Ming, Peron, Jean-Marie, Nguyen, Tien Quang, Yan, Lunan, Chiu, Chang-Fang, Santos, Florinda A., Veluvolu, Anil, Thungappa, Satheesh Chiradoni, Morgan, Claire, Parsons, Kerry, Xynos, Ioannis, Lencioni, Riccardo

Source: Journal of Clinical Oncology; 2024 Supplement, Vol. 42, p65-65, 48p

Overall Survival, BRAF, RAS, and MSI Status in Patients Who Underwent Cetuximab After Refractory Chemotherapy for Metastatic Colorectal Cancer.

Authors: Santos, Florinda A., Reis, Rui Manuel, Barroti, Lucas C., Pereira, Allan A. L., Matsushita, Marcus M., de Carvalho, Ana Carolina, Datorre, José Guilherme, Berardinelli, Gustavo N., Araujo, Raphael L. C.

Source: Journal of Gastrointestinal Cancer; Mar2024, Vol. 55 Issue 1, p344-354, 11p

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Accuracy and Clinical Relevance of Intra-Tumoral Fusobacterium nucleatum Detection in Formalin-Fixed Paraffin-Embedded (FFPE) Tissue by Droplet Digital PCR (ddPCR) in Colorectal Cancer.

Authors: Datorre, José Guilherme, de Carvalho, Ana Carolina, dos Reis, Mariana Bisarro, dos Reis, Monise, Matsushita, Marcus, Santos, Florinda, Guimarães, Denise Peixoto, Reis, Rui Manuel

Source: Diagnostics (2075-4418); Jan2022, Vol. 12 Issue 1, p114, 1p

Subject Terms: COLORECTAL cancer, FUSOBACTERIUM, MOLECULAR association, DNA, TISSUES, CALCINOSIS

Geographic Terms: BRAZIL

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