Genetic risk factors underlying white matter hyperintensities and cortical atrophy

Authors: Yash Patel, Jean Shin, Eeva Sliz, Ariana Tang, Aniket Mishra, Rui Xia, Edith Hofer, Hema Sekhar Reddy Rajula, Ruiqi Wang, Frauke Beyer, Katrin Horn, Max Riedl, Jing Yu, Henry Völzke, Robin Bülow, Uwe Völker, Stefan Frenzel, Katharina Wittfeld, Sandra Van der Auwera, Thomas H. Mosley, Vincent Bouteloup, Jean-Charles Lambert, Geneviève Chêne, Carole Dufouil, Christophe Tzourio, Jean-François Mangin, Rebecca F. Gottesman, Myriam Fornage, Reinhold Schmidt, Qiong Yang, Veronica Witte, Markus Scholz, Markus Loeffler, Gennady V. Roshchupkin, M. Arfan Ikram, Hans J. Grabe, Sudha Seshadri, Stephanie Debette, Tomas Paus, Zdenka Pausova

Source: Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/bf9509bdebd5484ea27088d73ad6ccb8

RIOK2 transcriptionally regulates TRiC and dyskerin complexes to prevent telomere shortening

Authors: Shrestha Ghosh, Mileena T. Nguyen, Ha Eun Choi, Maximilian Stahl, Annemarie Luise Kühn, Sandra Van der Auwera, Hans J. Grabe, Henry Völzke, Georg Homuth, Samuel A. Myers, Cory M. Hogaboam, Imre Noth, Fernando J. Martinez, Gregory A. Petsko, Laurie H. Glimcher

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/acac83437afc458ea79c24761644c96b

Unique genetic and risk-factor profiles in clusters of major depressive disorder-related multimorbidity trajectories

Authors: Andras Gezsi, Sandra Van der Auwera, Hannu Mäkinen, Nora Eszlari, Gabor Hullam, Tamas Nagy, Sarah Bonk, Rubèn González-Colom, Xenia Gonda, Linda Garvert, Teemu Paajanen, Zsofia Gal, Kevin Kirchner, Andras Millinghoffer, Carsten O. Schmidt, Bence Bolgar, Josep Roca, Isaac Cano, Mikko Kuokkanen, Peter Antal, Gabriella Juhasz

Source: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/43fb0a77e0ce443aa7add873f517e19c

Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance

Authors: Hao Mei, Jeannette Simino, Lianna Li, Fan Jiang, Joshua C. Bis, Gail Davies, W David Hill, Charley Xia, Vilmundur Gudnason, Qiong Yang, Jari Lahti, Jennifer A. Smith, Mirna Kirin, Philip De Jager, Nicola J. Armstrong, Mohsen Ghanbari, Ivana Kolcic, Christopher Moran, Alexander Teumer, Murali Sargurupremraj, Shamsed Mahmud, Myriam Fornage, Wei Zhao, Claudia L. Satizabal, Ozren Polasek, Katri Räikkönen, David C. Liewald, Georg Homuth, Michele Callisaya, Karen A. Mather, B. Gwen Windham, Tatijana Zemunik, Aarno Palotie, Alison Pattie, Sandra van der Auwera, Anbupalam Thalamuthu, David S. Knopman, Igor Rudan, John M. Starr, Katharina Wittfeld, Nicole A. Kochan, Michael E. Griswold, Veronique Vitart, Henry Brodaty, Rebecca Gottesman, Simon R. Cox, Bruce M. Psaty, Eric Boerwinkle, Daniel I. Chasman, Francine Grodstein, Perminder S. Sachdev, Velandai Srikanth, Caroline Hayward, James F. Wilson, Johan G. Eriksson, Sharon L. R. Kardia, Hans J. Grabe, David A. Bennett, M. Arfan Ikram, Ian J. Deary, Cornelia M. van Duijn, Lenore Launer, Annette L. Fitzpatrick, Sudha Seshadri, Jan Bressler, Stephanie Debette, Thomas H. Mosley

Source: Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)

Subject Terms: Genome-wide association study, Memory, Expression, Immunity, Multi-omics, Delayed recall, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1758-9193

Access URL: https://doaj.org/article/50a19bd7fce542089e5527e952a66f90

Identifying the Common Genetic Basis of Antidepressant Response

Authors: Oliver Pain, Karen Hodgson, Vassily Trubetskoy, Stephan Ripke, Victoria S. Marshe, Mark J. Adams, Enda M. Byrne, Adrian I. Campos, Tania Carrillo-Roa, Annamaria Cattaneo, Thomas D. Als, Daniel Souery, Mojca Z. Dernovsek, Chiara Fabbri, Caroline Hayward, Neven Henigsberg, Joanna Hauser, James L. Kennedy, Eric J. Lenze, Glyn Lewis, Daniel J. Müller, Nicholas G. Martin, Benoit H. Mulsant, Ole Mors, Nader Perroud, David J. Porteous, Miguel E. Rentería, Charles F. Reynolds, III, Marcella Rietschel, Rudolf Uher, Eleanor M. Wigmore, Wolfgang Maier, Naomi R. Wray, Katherine J. Aitchison, Volker Arolt, Bernhard T. Baune, Joanna M. Biernacka, Guido Bondolfi, Katharina Domschke, Masaki Kato, Qingqin S. Li, Yu-Li Liu, Alessandro Serretti, Shih-Jen Tsai, Gustavo Turecki, Richard Weinshilboum, Andrew M. McIntosh, Cathryn M. Lewis, Siegfried Kasper, Joseph Zohar, Stuart Montgomery, Diego Albani, Gianluigi Forloni, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Manuel Mattheisen, Maciej Trzaskowski, Abdel Abdellaoui, Esben Agerbo, Tracy M. Air, Till F.M. Andlauer, Silviu-Alin Bacanu, Marie Bækvad-Hansen, Aartjan T.F. Beekman, Tim B. Bigdeli, Elisabeth B. Binder, Julien Bryois, Henriette N. Buttenschøn, Jonas Bybjerg-Grauholm, Na Cai, Enrique Castelao, Jane Hvarregaard Christensen, Toni-Kim Clarke, Jonathan R.I. Coleman, Lucía Colodro-Conde, Baptiste Couvy-Duchesne, Nick Craddock, Gregory E. Crawford, Gail Davies, Ian J. Deary, Franziska Degenhardt, Eske M. Derks, Nese Direk, Conor V. Dolan, Erin C. Dunn, Thalia C. Eley, Valentina Escott-Price, Farnush Farhadi Hassan Kiadeh, Hilary K. Finucane, Jerome C. Foo, Andreas J. Forstner, Josef Frank, Héléna A. Gaspar, Michael Gill, Fernando S. Goes, Scott D. Gordon, Jakob Grove, Lynsey S. Hall, Christine Søholm Hansen, Thomas F. Hansen, Stefan Herms, Ian B. Hickie, Per Hoffmann, Georg Homuth, Carsten Horn, Jouke-Jan Hottenga, David M. Hougaard, David M. Howard, Marcus Ising, Rick Jansen, Ian Jones, Lisa A. Jones, Eric Jorgenson, James A. Knowles, Isaac S. Kohane, Julia Kraft, Warren W. Kretzschmar, Zoltán Kutalik, Yihan Li, Penelope A. Lind, Donald J. MacIntyre, Dean F. MacKinnon, Robert M. Maier, Jonathan Marchini, Hamdi Mbarek, Patrick McGrath, Peter McGuffin, Sarah E. Medland, Divya Mehta, Christel M. Middeldorp, Evelin Mihailov, Yuri Milaneschi, Lili Milani, Francis M. Mondimore, Grant W. Montgomery, Sara Mostafavi, Niamh Mullins, Matthias Nauck, Bernard Ng, Michel G. Nivard, Dale R. Nyholt, Paul F. O’Reilly, Hogni Oskarsson, Michael J. Owen, Jodie N. Painter, Carsten Bøcker Pedersen, Marianne Giørtz Pedersen, Roseann E. Peterson, Wouter J. Peyrot, Giorgio Pistis, Danielle Posthuma, Jorge A. Quiroz, Per Qvist, John P. Rice, Brien P. Riley, Margarita Rivera, Saira Saeed Mirza, Robert Schoevers, Eva C. Schulte, Ling Shen, Jianxin Shi, Stanley I. Shyn, Engilbert Sigurdsson, Grant C.B. Sinnamon, Johannes H. Smit, Daniel J. Smith, Hreinn Stefansson, Stacy Steinberg, Fabian Streit, Jana Strohmaier, Katherine E. Tansey, Henning Teismann, Alexander Teumer, Wesley Thompson, Pippa A. Thomson, Thorgeir E. Thorgeirsson, Matthew Traylor, Jens Treutlein, André G. Uitterlinden, Daniel Umbricht, Sandra Van der Auwera, Albert M. van Hemert, Alexander Viktorin, Peter M. Visscher, Yunpeng Wang, Bradley T. Webb, Shantel Marie Weinsheimer, Jürgen Wellmann, Gonneke Willemsen, Stephanie H. Witt, Yang Wu, Hualin S. Xi, Jian Yang, Futao Zhang, Klaus Berger, Dorret I. Boomsma, Sven Cichon, Udo Dannlowski, E.J.C. de Geus, J. Raymond DePaulo, Enrico Domenici, Tõnu Esko, Hans J. Grabe, Steven P. Hamilton, Andrew C. Heath, Kenneth S. Kendler, Stefan Kloiber, Susanne Lucae, Pamela A.F. Madden, Patrik K. Magnusson, Andres Metspalu, Preben Bo Mortensen, Bertram Müller-Myhsok, Merete Nordentoft, Markus M. Nöthen, Michael C. O’Donovan, Sara A. Paciga, Nancy L. Pedersen, Brenda W.J.H. Penninx, Roy H. Perlis, James B. Potash, Martin Preisig, Catherine Schaefer, Thomas G. Schulze, Jordan W. Smoller, Kari Stefansson, Henning Tiemeier, Henry Völzke, Myrna M. Weissman, Thomas Werge, Douglas F. Levinson, Gerome Breen, Anders D. Børglum, Patrick F. Sullivan

Source: Biological Psychiatry Global Open Science, Vol 2, Iss 2, Pp 115-126 (2022)

Subject Terms: Antidepressant response, Depression, Genetics, GWAS, MDD, Polygenic score, Psychiatry, RC435-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667174321000859; https://doaj.org/toc/2667-1743

Access URL: https://doaj.org/article/c97a14decdf44013b3e7f514e212f02f

Effects of Apolipoprotein E polymorphism on carotid intima-media thickness, incident myocardial infarction and incident stroke

Authors: Anitha Pitchika, Marcello Ricardo Paulista Markus, Sabine Schipf, Alexander Teumer, Sandra Van der Auwera, Matthias Nauck, Marcus Dörr, Stephan Felix, Hans-Jörgen Grabe, Henry Völzke, Till Ittermann

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/10987494f7464a88901302845499a59f

Detrimental Effects of ApoE ε4 on Blood–Brain Barrier Integrity and Their Potential Implications on the Pathogenesis of Alzheimer’s Disease

Authors: Kevin Kirchner, Linda Garvert, Luise Kühn, Sarah Bonk, Hans Jörgen Grabe, Sandra Van der Auwera

Source: Cells, Vol 12, Iss 21, p 2512 (2023)

Subject Terms: apolipoprotein E, amyloid beta, blood–brain barrier, cyclophilin A, low-density lipoprotein receptor-related protein1, matrix metalloproteinase 9, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/21/2512; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/9d59e1e10f4348e2a95f149932eb1e5e

Body mass index but not genetic risk is longitudinally associated with altered structural brain parameters

Authors: Anne Tüngler, Sandra Van der Auwera, Katharina Wittfeld, Stefan Frenzel, Jan Terock, Nele Röder, Georg Homuth, Henry Völzke, Robin Bülow, Hans Jörgen Grabe, Deborah Janowitz

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/84d477d626064ea2b1fcdf58b4fcc10e

Cortical and subcortical brain structure in generalized anxiety disorder: findings from 28 research sites in the ENIGMA-Anxiety Working Group

Authors: Anita Harrewijn, Elise M. Cardinale, Nynke A. Groenewold, Janna Marie Bas-Hoogendam, Moji Aghajani, Kevin Hilbert, Narcis Cardoner, Daniel Porta-Casteràs, Savannah Gosnell, Ramiro Salas, Andrea P. Jackowski, Pedro M. Pan, Giovanni A. Salum, Karina S. Blair, James R. Blair, Mira Z. Hammoud, Mohammed R. Milad, Katie L. Burkhouse, K. Luan Phan, Heidi K. Schroeder, Jeffrey R. Strawn, Katja Beesdo-Baum, Neda Jahanshad, Sophia I. Thomopoulos, Randy Buckner, Jared A. Nielsen, Jordan W. Smoller, Jair C. Soares, Benson Mwangi, Mon-Ju Wu, Giovana B. Zunta-Soares, Michal Assaf, Gretchen J. Diefenbach, Paolo Brambilla, Eleonora Maggioni, David Hofmann, Thomas Straube, Carmen Andreescu, Rachel Berta, Erica Tamburo, Rebecca B. Price, Gisele G. Manfro, Federica Agosta, Elisa Canu, Camilla Cividini, Massimo Filippi, Milutin Kostić, Ana Munjiza Jovanovic, Bianca A. V. Alberton, Brenda Benson, Gabrielle F. Freitag, Courtney A. Filippi, Andrea L. Gold, Ellen Leibenluft, Grace V. Ringlein, Kathryn E. Werwath, Hannah Zwiebel, André Zugman, Hans J. Grabe, Sandra Van der Auwera, Katharina Wittfeld, Henry Völzke, Robin Bülow, Nicholas L. Balderston, Monique Ernst, Christian Grillon, Lilianne R. Mujica-Parodi, Helena van Nieuwenhuizen, Hugo D. Critchley, Elena Makovac, Matteo Mancini, Frances Meeten, Cristina Ottaviani, Tali M. Ball, Gregory A. Fonzo, Martin P. Paulus, Murray B. Stein, Raquel E. Gur, Ruben C. Gur, Antonia N. Kaczkurkin, Bart Larsen, Theodore D. Satterthwaite, Jennifer Harper, Michael Myers, Michael T. Perino, Chad M. Sylvester, Qiongru Yu, Ulrike Lueken, Dick J. Veltman, Paul M. Thompson, Dan J. Stein, Nic J. A. Van der Wee, Anderson M. Winkler, Daniel S. Pine

Source: Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/2158-3188

Access URL: https://doaj.org/article/9d17f9f8582240abad7553d20434e213

Vitamin D moderates the interaction between 5-HTTLPR and childhood abuse in depressive disorders

Authors: Sarah Bonk, Johannes Hertel, Helena U. Zacharias, Jan Terock, Deborah Janowitz, Georg Homuth, Matthias Nauck, Henry Völzke, Henriette Meyer zu Schwabedissen, Sandra Van der Auwera, Hans Jörgen Grabe

Source: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/58b6e7edbd3d4ad4833732e5e5709209

Functional polymorphisms of the mineralocorticoid receptor gene NR3C2 are associated with diminished memory decline: Results from a longitudinal general‐population study

Authors: Jan Terock, Sandra Van der Auwera, Deborah Janowitz, Katharina Wittfeld, Alexander Teumer, Hans J. Grabe

Source: Molecular Genetics & Genomic Medicine, Vol 8, Iss 9, Pp n/a-n/a (2020)

Subject Terms: cognitive decline, mineralocorticoid receptor, NR3C2 gene, rs2070951, rs5522, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2324-9269

Access URL: https://doaj.org/article/d414fd23ec5c4548b05e27b95bddb5dc

APOE ε4 in Depression-Associated Memory Impairment—Evidence from Genetic and MicroRNA Analyses

Authors: Sarah Bonk, Kevin Kirchner, Sabine Ameling, Linda Garvert, Henry Völzke, Matthias Nauck, Uwe Völker, Hans J. Grabe, Sandra Van der Auwera

Source: Biomedicines, Vol 10, Iss 7, p 1560 (2022)

Subject Terms: amyloid beta, Alzheimer’s disease, APOE ε4, MDD, memory, miRNA, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/7/1560; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/6e76f3a51f5f40e9a96f7a2ec1eb92f3

Assessment of subjective emotional valence and long-lasting impact of life events: development and psychometrics of the Stralsund Life Event List (SEL)

Authors: Johanna König, Andrea Block, Mathias Becker, Kristin Fenske, Johannes Hertel, Sandra Van der Auwera, Kathleen Zymara, Henry Völzke, Harald Jürgen Freyberger, Hans Jörgen Grabe

Source: BMC Psychiatry, Vol 18, Iss 1, Pp 1-12 (2018)

Subject Terms: Positive life events, Negative life events, General population, Emotional valence, Depressive disorder, Psychiatry, RC435-571

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12888-018-1649-3; https://doaj.org/toc/1471-244X

Access URL: https://doaj.org/article/b071883379014d27a443b88c475cbb09

Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes

Authors: Beata Stepniak, Anne Kästner, Giulia Poggi, Marina Mitjans, Martin Begemann, Annette Hartmann, Sandra Van der Auwera, Farahnaz Sananbenesi, Dilja Krueger‐Burg, Gabriela Matuszko, Cornelia Brosi, Georg Homuth, Henry Völzke, Fritz Benseler, Claudia Bagni, Utz Fischer, Alexander Dityatev, Hans‐Jörgen Grabe, Dan Rujescu, Andre Fischer, Hannelore Ehrenreich

Source: EMBO Molecular Medicine, Vol 7, Iss 12, Pp 1565-1579 (2015)

Subject Terms: FMR1, FMR2, FXR1, FXR2, miR‐181, PGAS, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/fa13b93139ae4da49dc3ef49026ed8fb

ClassyFlu: classification of influenza A viruses with Discriminatively trained profile-HMMs.

Authors: Sandra Van der Auwera, Ingo Bulla, Mario Ziller, Anne Pohlmann, Timm Harder, Mario Stanke

Source: PLoS ONE, Vol 9, Iss 1, p e84558 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24404173/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/db53bf2324ce4aa9850d5469777e25aa

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