Ageing alters the severity of Sunitinib-induced cardiotoxicity: Investigating the mitogen activated kinase kinase 7 pathway association

Authors: Cooper, Samantha, Sandhu, Hardip, Hussain, Afthab, Mee, Christopher, Maddock, Helen

Source: In Toxicology 1 January 2019 411:49-59

Involvement of mitogen activated kinase kinase 7 intracellular signalling pathway in Sunitinib-induced cardiotoxicity

Authors: Cooper, Samantha Louise, Sandhu, Hardip, Hussain, Afthab, Mee, Christopher, Maddock, Helen

Source: In Toxicology 1 February 2018 394:72-83

Attenuation of Sunitinib-induced cardiotoxicity through the A3 adenosine receptor activation

Authors: Sandhu, Hardip, Cooper, Samantha, Hussain, Afthab, Mee, Christopher, Maddock, Helen

Source: In European Journal of Pharmacology 5 November 2017 814:95-105

Doxorubicin alters G-protein coupled receptor-mediated vasocontraction in rat coronary arteries.

Authors: Lozahic, Caroline, Maddock, Helen, Wheatley, Mark, Sandhu, Hardip

Source: Naunyn-Schmiedeberg's Archives of Pharmacology; Aug2024, Vol. 397 Issue 8, p5831-5845, 15p

Subject Terms: G protein coupled receptors, VASCULAR smooth muscle, ENDOTHELIN receptors, CHEMOTHERAPY complications, SEROTONIN receptors

Alteration in contractile G-protein coupled receptor expression by moist snus and nicotine in rat cerebral arteries

Authors: Sandhu, Hardip, Xu, Cang-Bao, Edvinsson, Lars

Source: In Toxicology and Applied Pharmacology 2011 252(2):138-149

Comparison of MEK/ERK pathway inhibitors on the upregulation of vascular G-protein coupled receptors in rat cerebral arteries

Authors: Sandhu, Hardip, Ansar, Saema, Edvinsson, Lars

Source: In European Journal of Pharmacology 10 October 2010 644(1-3):128-137

Upregulation of contractile endothelin type B receptors by lipid-soluble cigarette smoking particles in rat cerebral arteries via activation of MAPK

Authors: Sandhu, Hardip, Xu, Cang Bao, Edvinsson, Lars

Source: In Toxicology and Applied Pharmacology 2010 249(1):25-32

Doxorubicin-induced cardiotoxicity: Investigating the effect on miRNA expression and G-protein coupled receptors mediated vascular tone

Authors: Lozahic, Caroline, Wheatley, Mark, Maddock, Helen, Sandhu, Hardip

Source: In Journal of Pharmacological and Toxicological Methods September-October 2021 111

Cardiovascular implications and physical activity in middle-aged and older adults with a history of COVID-19 (CV COVID): a protocol for a randomised controlled trial.

Authors: Rahman, Mushidur, Russell, Sophie L., Okwose, Nduka C., Hood, Olivia M. A., Harwood, Amy E., McGregor, Gordon, Raleigh, Stuart M., Sandhu, Hardip, Roden, Laura C., Maddock, Helen, Banerjee, Prithwish, Jakovljevic, Djordje G.

Source: Trials; 5/13/2023, Vol. 24 Issue 1, p1-9, 9p, 1 Black and White Photograph, 1 Diagram, 1 Chart

Subject Terms: BRAIN natriuretic factor, GLOBAL longitudinal strain, EXERCISE tests, MIDDLE-aged persons, VASCULAR endothelial growth factors, RANDOMIZED controlled trials, PHYSICAL activity

Metformin Protects Against Sunitinib-induced Cardiotoxicity: Investigating the Role of AMPK.

Authors: Kuburas, Refik, Gharanei, Mayel, Haussmann, Irmgard, Maddock, Helen, Sandhu, Hardip

Source: Journal of Cardiovascular Pharmacology; Jun2022, Vol. 79 Issue 6, p799-807, 9p

The effect of COVID-19 on cardiovascular function and exercise tolerance in healthy middle-age and older individuals.

Authors: Russell, Sophie L.¹ (AUTHOR), Okwose, Nduka C.¹ (AUTHOR), Rahman, Mushidur¹ (AUTHOR), Lee, Ben J² (AUTHOR), McGregor, Gordon^3,4,5 (AUTHOR), Raleigh, Stuart M.¹ (AUTHOR), Sandhu, Hardip¹ (AUTHOR), Roden, Laura C.¹ (AUTHOR), Banerjee, Prithwish^1,5,6 (AUTHOR), Jakovljevic, Djordje G.^1,6 (AUTHOR) djordje.jakovljevic@coventry.ac.uk

Source: Scandinavian Cardiovascular Journal. Feb2025, p1-10. 10p. 1 Illustration.

Subject Terms: *PULSE wave analysis, *EXERCISE tolerance, *EXERCISE tests, *OLDER people, *ANAEROBIC threshold

Investigating the Cardioprotective Role of Metformin During Sunitinib-Induced Cardiotoxicity by qRT-PCR Profiling of microRNAs Associated with Myocardial Injury

Authors: Sandhu, Hardip, Maddock, Helen

Source: In Journal of Pharmacological and Toxicological Methods November-December 2017 88 Part 2:218-218

The Early Assessment of the Cardioprotective Properties of Metformin during Sunitinib-Induced Cytotoxicity

Authors: Kuburas, Refik, Gharanei, Mayel, Haussmann, Irmgard, Maddock, Helen, Sandhu, Hardip

Source: In Journal of Pharmacological and Toxicological Methods November-December 2017 88 Part 2:218-218

Sunitinib-Induced Cardiotoxicity is Age Dependant and Involves Mitogen Activated Kinase Kinase 7 (MKK7)

Authors: Cooper, Samantha, Mee, Christopher, Hussain, Afthab, Maddock, Helen, Sandhu, Hardip

Source: In Journal of Pharmacological and Toxicological Methods November-December 2017 88 Part 2:216-216

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Mitogen activated kinase kinase 7 is involved in Sunitinib induced myocardial injury

Authors: Cooper, Samantha, Maddock, Helen, Hussain, Afthab, Sandhu, Hardip

Source: In Journal of Pharmacological and Toxicological Methods September-October 2016 81:341-341

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Involvement of mitogen activated kinase kinase 7 in tyrosine kinase inhibitor-induced myocardial injury

Authors: Cooper, Samantha, Sandhu, Hardip, Hussain, Afthab, Maddock, Helen

Source: In Journal of Pharmacological and Toxicological Methods September-October 2015 75:169-169

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Myocardial injury associated with salbutamol administration under ischaemic myocardial stress conditions is associated with altered microRNA expression

Authors: Nagra, Aaron, Sandhu, Hardip, Naz, Humma, Hussain, Afthab

Source: In Journal of Pharmacological and Toxicological Methods July-August 2013 68(1):e27-e27