Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation

Authors: Amenyogbe, Nelly, Angelidou, Asimenia, Bao, Winnie, Ben-Othman, Rym, Bennike, Tue, Blimkie, Travis, Bjerregaard-Andersen, Morten, Brinkman, Ryan R., Brook, Byron, Burnell, Kendyll, Cai, Bing, Checkervarty, Abhinav, Chen, Jing, Chen, Virginia, Cooney, Mitchell, Cox, Momoudou, Darboe, Alansana, Dhillon, Bhavjinder K., Dibassey, Tida, Diray-Arce, Joann, Falsafi, Reza, Fatou, Benoit, Ford, Rebecca, Francis, Freddy, Golding, Christian N., Hancock, Robert E.W., Harbeson, Danny J., He, Daniel, Hinshaw, Samuel H., Hoch, Annmarie, Huang, Joe, Idoko, Olubukola T., Imam, Abdulazeez, Kampmann, Beate, Kirarock, Wendy, Kollmann, Tobias R., Karoly, Meagan E., Kraft, Ken, Larsen, Kristina, Lasky-Su, Jessica, Lee, Amy H., Levy, Ofer, Liu, Aaron, A, Liu, Mark, M, Malek, Mehrnoush, Marchant, Arnaud, Masiria, Geraldine, Martino, David Jim, Matlam, John Paul, McEnaney, Kerry, McLoughlin, Caitlyn, Montante, Sebastiano, Morrocchi, Elena, Ndure, Jorjoh, Nguyen, Athena, Njie-Jobe, Jainaba, Odumade, Oludare A., Ozonoff, Al, Pak, Jensen, Palma, Paolo, Parker, Edward P.K., Pettengill, Matthew A., Plotkin, Alec, Pomat, William S., Rao, Shun, Richmond, Peter C., Roberts, Elishia, Saleu, Gerard, Sanca, Lilica, Sanchez-Schmitz, Guzman, Schaltz-Buchholzer, Frederik, Shannon, Casey P., Singh, Amrit, Smith, Maren, Smolen, Kinga K., Steen, Hanno, Strandmark, Julia, Syphurs, Caitlin, Tebbutt, Scott J., van den Biggelaar, Anita H.J., van Haren, Simon D., Varankovich, Natallia, Vignolo, Sofia, Vo, Diana, Wariri, Oghenebrume, An, Andy Y., Acton, Erica, Blimkie, Travis M., Dibbasey, Tida, Bennike, Tue Bjerg, Martino, David

Source: In eBioMedicine December 2024 110

The BNT162b2 mRNA vaccine demonstrates reduced age-associated TH1 support in vitro and in vivo

Authors: Brook, Byron ^{1, 2}, Checkervarty, Abhinav Kumar ^{1, 3, 4}, Barman, Soumik ^{1, 2}, Sweitzer, Cali ¹, Bosco, Anna-Nicole ¹, Sherman, Amy C. ^{1, 5}, Baden, Lindsey R. ⁵, Morrocchi, Elena ^{1, 2, 6}, Sanchez-Schmitz, Guzman ^{1, 2}, Palma, Paolo ^{6, 7}, Nanishi, Etsuro ^{1, 2}, O’Meara, Timothy R. ¹, McGrath, Marisa E. ⁸, Frieman, Matthew B. ⁸, Soni, Dheeraj ⁹, van Haren, Simon D. ^{1, 2}, Ozonoff, Al ^{1, 2, 10}, Diray-Arce, Joann ^{1, 2}, Steen, Hanno ^{1, 11}, Dowling, David J. ^{1, 2, 12, ∗}, Levy, Ofer ^{1, 2, 10, 12, 13, ∗∗}

Source: In iScience 15 November 2024 27(11)

Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

Authors: Lee, Amy, Shannon, Casey, Amenyogbe, Nelly, Bennike, Tue, Diray-Arce, Joann, Idoko, Olubukola, Gill, Erin, Ben-Othman, Rym, Pomat, William, Haren, Simon D., Cao, Kim-Anh, Cox, Momoudou, Darboe, Alansana, Falsafi, Reza, Ferrari, Davide, Harbeson, Daniel, He, Daniel, Bing, Cai, Hinshaw, Samuel, Ndure, Jorjoh, Njie-Jobe, Jainaba, Pettengill, Matthew, Richmond, Peter, Ford, Rebecca, Saleu, Gerard, Masiria, Geraldine, Matlam, John, Kirarock, Wendy, Roberts, Elishia, Malek, Mehrnoush, Sanchez-Schmitz, Guzmán, Singh, Amrit, Angelidou, Asimenia, Smolen, Kinga, Brinkman, Ryan, Ozonoff, Al, Hancock, Robert, Biggelaar, Anita, Steen, Hanno, Tebbutt, Scott, Kampmann, Beate, Levy, Ofer, Kollmann, Tobias

Source: Nature communications. 10(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127965071.0x000001&indx=1&recIds=ETOCvdc_100127965071.0x000001

Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses

Authors: Dowling, David J., Scott, Evan A., Scheid, Annette, Bergelson, Ilana, Joshi, Sweta, Pietrasanta, Carlo, Brightman, Spencer, Sanchez-Schmitz, Guzman, Van Haren, Simon D., Ninković, Jana, Kats, Dina, Guiducci, Cristiana, de Titta, Alexandre, Bonner, Daniel K., Hirosue, Sachiko, Swartz, Melody A., Hubbell, Jeffrey A., Levy, Ofer

Source: In The Journal of Allergy and Clinical Immunology November 2017 140(5):1339-1350

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