RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis

Authors: Dopeso, Higinio, Rodrigues, Paulo, Cartón-García, Fernando, Macaya, Irati, Bilic, Josipa, Anguita, Estefanía, Jing, Li, Brotons, Bruno, Vivancos, Núria, Beà, Laia, Sánchez-Martín, Manuel, Landolfi, Stefania, Hernandez-Losa, Javier, Ramon y Cajal, Santiago, Nieto, Rocío, Vicario, María, Farre, Ricard, Schwartz, Simo, Jr., van Ijzendoorn, Sven C.D., Kobayashi, Kazuto, Martinez-Barriocanal, Águeda, Arango, Diego

Source: In iScience 19 April 2024 27(4)

A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors

Authors: Fernández-Pisonero, Isabel, Clavaín, Laura, Robles-Valero, Javier, Lorenzo-Martín, L. Francisco, Caloto, Rubén, Nieto, Blanca, García-Macías, Carmen, Oeste, Clara L., Sánchez-Martín, Manuel, Abad, Antonio, Hortal, Alejandro, Caballero, Dolores, González, Marcos, Dosil, Mercedes, Alarcón, Balbino, Bustelo, Xosé R.

Source: In Cell Reports 15 March 2022 38(11)

Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles

Authors: Fernandez-Guerrero, Marc, Yakushiji-Kaminatsui, Nayuta, Lopez-Delisle, Lucille, Zdral, Sofía, Darbellay, Fabrice, Perez-Gomez, Rocío, Bolt, Christopher Chase, Sanchez-Martin, Manuel A., Duboule, Denis, Ros, Marian A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Dec 01. 117(48), 30509-30519.

Access URL: https://www.jstor.org/stable/26971125

Molecular analysis of ex-vivo CD133+ GBM cells revealed a common invasive and angiogenic profile but different proliferative signatures among high grade gliomas

Authors: Garcia Juan L, Perez-Caro Maria, Gomez-Moreta Juan A, Gonzalez Francisco, Ortiz Javier, Blanco Oscar, Sancho Magdalena, Hernandez-Rivas Jesus M, Gonzalez-Sarmiento Rogelio, Sanchez-Martin Manuel

Source: BMC Cancer, Vol 10, Iss 1, p 454 (2010)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2407/10/454; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/146a8b320a934adbbe9687993622cc0e

Zinc-finger transcription factor Slug contributes to the function of the stem cell factor c-kit signaling pathway

Authors: Pérez-Losada, Jesus, Sánchez-Martı́n, Manuel, Rodrı́guez-Garcı́a, Arancha, Sánchez, Maria Luz, Orfao, Alberto, Flores, Teresa, Sánchez-Garcı́a, Isidro

Source: In Blood 15 August 2002 100(4):1274-1286

The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug.

Authors: Perez-Losada, Jesus, Sanchez-Martin, Manuel, Perez-Caro, Maria, Perez-Mancera, Pedro A, Sanchez-Garcia, Isidro

Source: Oncogene. 7/3/2003, Vol. 22 Issue 27, p4205. 7p.

Subject Terms: *ZINC-finger proteins, *TRANSCRIPTION factors, *HEMATOPOIESIS, *STEM cells, *CELLULAR signal transduction

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FRI-422-Genetic and pathophysiological factors leading to deficient acyl-CoA oxidase 2 (ACOX2) activity in hepatocytes, an alteration which causes oxidative and endoplasmic reticulum stress in liver cells

Authors: Alonso-Peña, Marta, Hermanns, Heike, Herraez, Elisa, Briz, Oscar, Monte, Maria, Sánchez-Martín, Manuel, Berrocal, Pablo, Garcia-Tuñon, Ignacio, Espinosa-Escudero, Ricardo A., Prieto, Jesus, Geier, Andreas, Marin, Jose

Source: In Journal of Hepatology April 2019 70(1) Supplement:e579-e579

P-258 - Monitoring intracellular hydrogen peroxide changes in skeletal muscle fibres by HyPer, a genetically encoded hydrogen peroxide biosensor

Authors: Fernández-Puente, Escarlata, Sánchez-Martin, Manuel A, Mendez, Lucia, Palomero, Jesús

Source: In Free Radical Biology and Medicine 20 May 2018 120 Supplement 1:S123-S123

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P 117 - HyPer biosensor to monitor intracellular hydrogen peroxide in skeletal muscle cells

Authors: Sánchez-Martín, Manuel Adolfo, Andrés, Jorge de, Rodríguez-Izquierdo, Lorena, Méndez, Lucía, Palomero, Jesús

Source: In Free Radical Biology and Medicine July 2017 108 Supplement 1:S57-S57

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