Spatial characterization of RPE structure and lipids in the PEX1-p.Gly844Asp mouse model for Zellweger spectrum disorder

Authors: Samy Omri, Catherine Argyriou, Rachel S. Pryce, Erminia Di Pietro, Pierre Chaurand, Nancy Braverman

Source: Journal of Lipid Research, Vol 66, Iss 4, Pp 100771- (2025)

Subject Terms: dyslipidemia, eye/retina, inflammation, lipidomics, lipids, mass spectrometry imaging, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227525000318; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/925d9b172a4849beb0039e0327f0ed7a

AAV-mediated PEX1 gene augmentation improves visual function in the PEX1-Gly844Asp mouse model for mild Zellweger spectrum disorder

Authors: Catherine Argyriou, Anna Polosa, Ji Yun Song, Samy Omri, Bradford Steele, Bruno Cécyre, Devin S. McDougald, Erminia Di Pietro, Jean-François Bouchard, Jean Bennett, Joseph G. Hacia, Pierre Lachapelle, Nancy E. Braverman

Source: Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 225-240 (2021)

Subject Terms: peroxisome biogenesis disorder, Zellweger spectrum disorder, PEX1, retinal gene therapy, AAV therapy, metabolic disorder gene therapy, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050121001376; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/8cbf07d636cf46afa1661d18efa2eb4c

An allosteric interleukin-1 receptor modulator mitigates inflammation and photoreceptor toxicity in a model of retinal degeneration

Authors: Rabah Dabouz, Colin W. H. Cheng, Pénélope Abram, Samy Omri, Gael Cagnone, Khushnouma Virah Sawmy, Jean-Sébastien Joyal, Michel Desjarlais, David Olson, Alexander G. Weil, William Lubell, José Carlos Rivera, Sylvain Chemtob

Source: Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-19 (2020)

Subject Terms: Retinal degeneration, Photoreceptors, cell death, Inflammation, Inflammasome, Interleukin-1, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/506aa30b38074c1d9d6c7c66eb9f544b

Tyrosine-Protein Phosphatase Non-receptor Type 9 (PTPN9) Negatively Regulates the Paracrine Vasoprotective Activity of Bone-Marrow Derived Pro-angiogenic Cells: Impact on Vascular Degeneration in Oxygen-Induced Retinopathy

Authors: Michel Desjarlais, Pakiza Ruknudin, Maëlle Wirth, Isabelle Lahaie, Rabah Dabouz, José Carlos Rivera, Tiffany Habelrih, Samy Omri, Pierre Hardy, Alain Rivard, Sylvain Chemtob

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: pro-angiogenic cell, vascular degeneration, tyrosine-protein phosphatase non-receptor type 9, oxygen-induced retinopathy, angiogenesis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.679906/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/8897c27c0d2f4502b53fdb07ee39e51b

Mesenchymal Stromal Cells Promote Retinal Vascular Repair by Modulating Sema3E and IL-17A in a Model of Ischemic Retinopathy

Authors: Baraa Noueihed, José Carlos Rivera, Rabah Dabouz, Pénélope Abram, Samy Omri, Isabelle Lahaie, Sylvain Chemtob

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: interleukin-17A, semaphorin 3E, ischemic retinopathies, vascular regeneration, mesenchymal stem cells, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.630645/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/618cc221bcd24071a2b85b2557f3586c

The Succinate Receptor SUCNR1 Resides at the Endoplasmic Reticulum and Relocates to the Plasma Membrane in Hypoxic Conditions

Authors: Melanie Sanchez, David Hamel, Emmanuel Bajon, François Duhamel, Vikrant K. Bhosle, Tang Zhu, Jose Carlos Rivera, Rabah Dabouz, Mathieu Nadeau-Vallée, Nicholas Sitaras, David-Étienne Tremblay, Samy Omri, Tiffany Habelrih, Raphael Rouget, Xin Hou, Fernand Gobeil, Jean-Sébastien Joyal, Przemyslaw Sapieha, Grant Mitchell, Alfredo Ribeiro-Da-Silva, Mohammad Ali Mohammad Nezhady, Sylvain Chemtob

Source: Cells, Vol 11, Iss 14, p 2185 (2022)

Subject Terms: SUCNR1/GPR91, succinate, GPCR, N-glycosylation, endoplasmic reticulum, angiogenesis, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/14/2185; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/08718907106b4199a8f209beb94c4878

Novel Anti-Interleukin-1β Therapy Preserves Retinal Integrity: A Longitudinal Investigation Using OCT Imaging and Automated Retinal Segmentation in Small Rodents

Authors: Diane N. Sayah, Tianwei E. Zhou, Samy Omri, Javier Mazzaferri, Christiane Quiniou, Maëlle Wirth, France Côté, Rabah Dabouz, Michel Desjarlais, Santiago Costantino, Sylvain Chemtob

Source: Frontiers in Pharmacology, Vol 11 (2020)

Subject Terms: rytvela, kineret, anti-interleukin-1β, therapy, oxygen-induced retinopathy, retina, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2020.00296/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/517d3ff6c4aa43ef846cb4aa5a9b4ca5

MicroRNA-96 Promotes Vascular Repair in Oxygen-Induced Retinopathy—A Novel Uncovered Vasoprotective Function

Authors: Michel Desjarlais, Maëlle Wirth, José Carlos Rivera, Isabelle Lahaie, Rabah Dabouz, Samy Omri, Pakiza Ruknudin, Celine Borras, Sylvain Chemtob

Source: Frontiers in Pharmacology, Vol 11 (2020)

Subject Terms: micro-RNA (miRNA), vascular degeneration, vascular repair and angiogenesis, oxygen-induced retinopathy (OIR), endothelial dysfunction, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2020.00013/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/a3af8494e69948a9855d7f4b472db4b9

MicroRNA expression profile in retina and choroid in oxygen-induced retinopathy model.

Authors: Michel Desjarlais, Jose Carlos Rivera, Isabelle Lahaie, Gaël Cagnone, Maëlle Wirt, Samy Omri, Sylvain Chemtob

Source: PLoS ONE, Vol 14, Iss 6, p e0218282 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/623050ef1c944734bd2b321a91375b84

Azasulfurylpeptide Modulation of CD36-Mediated Inflammation Without Effect on Neovascularization

Authors: Stéphane Turcotte, Katia Mellal, Ramesh Chingle, Mukandila Mulumba, Samy Omri, Lylia Dif-Yaiche, Sylvain Chemtob, Huy Ong, William D. Lubell

Source: Biomedicines, Vol 6, Iss 4, p 98 (2018)

Subject Terms: age-related macular degeneration, azapeptide, azasulfurylpeptide, cluster of differentiation 36, fibroblast-stimulating lipopeptide, growth hormone-releasing peptide-6, N-Aminosulfamide, nitric oxide, semicarbazide, toll-like receptor, tumor necrosis factor-α, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.mdpi.com/2227-9059/6/4/98; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/1e4d6c5f99664b619bd18102e4c19a2d

PKCζ mediates breakdown of outer blood-retinal barriers in diabetic retinopathy.

Authors: Samy Omri, Francine Behar-Cohen, Pierre-Raphaël Rothschild, Emmanuelle Gélizé, Laurent Jonet, Jean Claude Jeanny, Boubaker Omri, Patricia Crisanti

Source: PLoS ONE, Vol 8, Iss 11, p e81600 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3843687?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c65f7410bd664ed28f54eb0c84be339e

Placental growth factor contributes to micro-vascular abnormalization and blood-retinal barrier breakdown in diabetic retinopathy.

Authors: Laura Kowalczuk, Elodie Touchard, Samy Omri, Laurent Jonet, Christophe Klein, Fatemeh Valamanes, Marianne Berdugo, Pascal Bigey, Pascale Massin, Jean-Claude Jeanny, Francine Behar-Cohen

Source: PLoS ONE, Vol 6, Iss 3, p e17462 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3049767?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/5b1ae9299bb54e1ab5e5bac6eb2a9ee3