Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease

Authors: Daehong Kim, Giljun Park, Jani Huuhtanen, Sofie Lundgren, Rajiv K. Khajuria, Ana M. Hurtado, Cecilia Muñoz-Calleja, Laura Cardeñoso, Valle Gómez-García de Soria, Tzu Hua Chen-Liang, Samuli Eldfors, Pekka Ellonen, Sari Hannula, Matti Kankainen, Oscar Bruck, Anna Kreutzman, Urpu Salmenniemi, Tapio Lönnberg, Andrés Jerez, Maija Itälä-Remes, Mikko Myllymäki, Mikko A. I. Keränen, Satu Mustjoki

Source: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ea0ed950dd9b43599b0f71b6f958e251

Corrigendum: Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature

Authors: Tiina Kelkka, Paula Savola, Dipabarna Bhattacharya, Jani Huuhtanen, Tapio Lönnberg, Matti Kankainen, Kirsi Paalanen, Mikko Tyster, Maija Lepistö, Pekka Ellonen, Johannes Smolander, Samuli Eldfors, Bhagwan Yadav, Sofia Khan, Riitta Koivuniemi, Christopher Sjöwall, Laura L. Elo, Harri Lähdesmäki, Yuka Maeda, Hiroyoshi Nishikawa, Marjatta Leirisalo-Repo, Tuulikki Sokka-Isler, Satu Mustjoki

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: rheumatoid arthritis, seronegative, ACPA-negative, CD8+ lymphocyte, T cell receptor, somatic mutation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.710831/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/0ae39758c3764572a874d0ca3de3022f

Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature

Authors: Tiina Kelkka, Paula Savola, Dipabarna Bhattacharya, Jani Huuhtanen, Tapio Lönnberg, Matti Kankainen, Kirsi Paalanen, Mikko Tyster, Maija Lepistö, Pekka Ellonen, Johannes Smolander, Samuli Eldfors, Bhagwan Yadav, Sofia Khan, Riitta Koivuniemi, Christopher Sjöwall, Laura L. Elo, Harri Lähdesmäki, Yuka Maeda, Hiroyoshi Nishikawa, Marjatta Leirisalo-Repo, Tuulikki Sokka-Isler, Satu Mustjoki

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: rheumatoid arthritis, seronegative, ACPA-negative, CD8+ lymphocyte, T cell receptor, somatic mutation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.578848/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/269cd4fa96c4412898c4b325a9f2ac64

Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target

Authors: Olli Dufva, Matti Kankainen, Tiina Kelkka, Nodoka Sekiguchi, Shady Adnan Awad, Samuli Eldfors, Bhagwan Yadav, Heikki Kuusanmäki, Disha Malani, Emma I Andersson, Paavo Pietarinen, Leena Saikko, Panu E. Kovanen, Teija Ojala, Dean A. Lee, Thomas P. Loughran, Hideyuki Nakazawa, Junji Suzumiya, Ritsuro Suzuki, Young Hyeh Ko, Won Seog Kim, Shih-Sung Chuang, Tero Aittokallio, Wing C. Chan, Koichi Ohshima, Fumihiro Ishida, Satu Mustjoki

Source: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a90516e221ea4f0c9791e1e130cc3ead

Somatic mutations and T-cell clonality in patients with immunodeficiency

Authors: Paula Savola, Timi Martelius, Matti Kankainen, Jani Huuhtanen, Sofie Lundgren, Yrjö Koski, Samuli Eldfors, Tiina Kelkka, Mikko A.I. Keränen, Pekka Ellonen, Panu E. Kovanen, Soili Kytölä, Janna Saarela, Harri Lähdesmäki, Mikko R.J. Seppänen, Satu Mustjoki

Source: Haematologica, Vol 105, Iss 12 (2019)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/9576; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/69540fc6d5494d5cbc5fe42bc36544ea