Plasmodium falciparum reticulocyte-binding homologues are targets of human inhibitory antibodies and play a role in immune evasion

Authors: Linda Reiling, Kristina E. M. Persson, Fiona J. McCallum, Nimmo Gicheru, Samson M. Kinyanjui, Chetan E. Chitnis, Freya J. I. Fowkes, Kevin Marsh, James G. Beeson

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: P. falciparum, inhibitory antibodies, phenotypic variation, immune evasion, reticulocyte binding homologues, RH proteins, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1532451/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/4d60ba3e19704b238769d67d953e254d

Antibody-Dependent Respiratory Burst against Plasmodium falciparum Merozoites in Individuals Living in an Area with Declining Malaria Transmission

Authors: Doreen D. Mutemi, James Tuju, Rodney Ogwang, Lydia Nyamako, Kennedy M. Wambui, Ivette R. Cruz, Pär Villner, Victor Yman, Samson M. Kinyanjui, Ingegerd Rooth, Billy Ngasala, Anna Färnert, Faith H. A. Osier

Source: Vaccines, Vol 12, Iss 2, p 203 (2024)

Subject Terms: Plasmodium falciparum, malaria, transmission, ADRB, immunity, vaccines, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/2/203; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/b268b86836494599a872943934959601

Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya

Authors: George Githinji, Zaydah R. de Laurent, Khadija Said Mohammed, Donwilliams O. Omuoyo, Peter M. Macharia, John M. Morobe, Edward Otieno, Samson M. Kinyanjui, Ambrose Agweyu, Eric Maitha, Ben Kitole, Thani Suleiman, Mohamed Mwakinangu, John Nyambu, John Otieno, Barke Salim, Kadondi Kasera, John Kiiru, Rashid Aman, Edwine Barasa, George Warimwe, Philip Bejon, Benjamin Tsofa, Lynette Isabella Ochola-Oyier, D. James Nokes, Charles N. Agoti

Source: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a034766731d140dba3068aa4fac4efdf

Breadth of Antibodies to Plasmodium falciparum Variant Surface Antigens Is Associated With Immunity in a Controlled Human Malaria Infection Study

Authors: Hannah W. Kimingi, Ann W. Kinyua, Nicole A. Achieng, Kennedy M. Wambui, Shaban Mwangi, Roselyne Nguti, Cheryl A. Kivisi, Anja T. R. Jensen, Philip Bejon, Melisa C. Kapulu, Abdirahman I. Abdi, Samson M. Kinyanjui, CHMI-SIKA Study Team, Abdirahman I Abdi, Yonas Abebe, Agnes Audi, Peter Billingsley, Peter C Bull, Primus Che, Zaydah de Laurent, Susanne H Hodgson, Stephen Hoffman, Eric James, Irene Jao, Dorcas Kamuya, Gathoni Kamuyu, Silvia Kariuki, Nelson Kibinge, Sam Kinyanjui, Cheryl Kivisi, Nelly Koskei, Mallika Imwong, Brett Lowe, Johnstone Makale, Kevin Marsh, Vicki Marsh, Khadija Said Mohammed, Moses Mosobo, Sean C Murphy, Jennifer Musyoki, Michelle Muthui, Jedidah Mwacharo, Daniel Mwanga, Joyce Mwongeli, Francis Ndungu, Maureen Njue, George Nyangweso, Domitila Kimani, Joyce M. Ngoi, Janet Musembi, Omar Ngoto, Edward Otieno, Bernhards Ogutu, Fredrick Olewe, James Oloo, Donwilliams Omuoyo, John Ongecha, Martin O Ongas, Michael Ooko, Jimmy Shangala, Betty Kim Lee Sim, Joel Tarning, Juliana Wambua, Thomas N Williams, Markus Winterberg

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: malaria, Plasmodium falciparum, CHMI, variant surface antigens, anti-VSA antibodies, antibody breadth, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.894770/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/330b0f288975431b9dc0453fdfdfcfe9

The burden of neurological impairments and disability in older children measured in disability-adjusted life-years in rural Kenya

Authors: Jonathan A. Abuga, Symon M. Kariuki, Amina Abubakar, Samson M. Kinyanjui, Michael Boele van Hensbroek, Charles R. Newton

Source: PLOS Global Public Health, Vol 2, Iss 2 (2022)

Subject Terms: Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612656/?tool=EBI; https://doaj.org/toc/2767-3375

Access URL: https://doaj.org/article/7e442dfbb25c4c0798c46bc2af53b181

Barriers to access and utilization of healthcare by children with neurological impairments and disability in low-and middle-income countries: a systematic review [version 2; peer review: 2 approved]

Authors: Jonathan A. Abuga, Lucy W. Mwangi, Symon M. Kariuki, Emma Cottrell, Charles RJC. Newton, Samson M. Kinyanjui

Source: Wellcome Open Research, Vol 6 (2022)

Subject Terms: healthcare, neurological impairments, disability, rehabilitation, resource-limited settings, eng, Medicine, Science

File Description: electronic resource

Relation: https://wellcomeopenresearch.org/articles/6-61/v2; https://doaj.org/toc/2398-502X

Access URL: https://doaj.org/article/2a2fa9b0c553438d84f75a9cabba6a24

Premature Mortality, Risk Factors, and Causes of Death Following Childhood-Onset Neurological Impairments: A Systematic Review

Authors: Jonathan A. Abuga, Symon M. Kariuki, Samson M. Kinyanjui, Michael Boele van Hensbroek, Charles R. Newton

Source: Frontiers in Neurology, Vol 12 (2021)

Subject Terms: neurological, neurodevelopmental, disability, impairment, mortality, children, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2021.627824/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/05054506156a4e4bb3f176ccd3cbdbad

KILchip v1.0: A Novel Plasmodium falciparum Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization

Authors: Gathoni Kamuyu, James Tuju, Rinter Kimathi, Kennedy Mwai, James Mburu, Nelson Kibinge, Marisa Chong Kwan, Sam Hawkings, Reuben Yaa, Emily Chepsat, James M. Njunge, Timothy Chege, Fatuma Guleid, Micha Rosenkranz, Christopher K. Kariuki, Roland Frank, Samson M. Kinyanjui, Linda M. Murungi, Philip Bejon, Anna Färnert, Kevin K. A. Tetteh, James G. Beeson, David J. Conway, Kevin Marsh, Julian C. Rayner, Faith H. A. Osier

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: Plasmodium falciparum, merozoite, antibodies, vaccine candidates, protein microarray, bioinformatics, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.02866/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/5831dc4ac3f8459aafd4718c6ad4374f

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Premature mortality in children aged 6–9 years with neurological impairments in rural Kenya: a cohort study

Authors: Jonathan A Abuga, MPH, Symon M Kariuki, DPhil, Samson M Kinyanjui, PhD, Michaël Boele Van Hensbroek, MD, Charles RJC Newton, MD

Source: The Lancet Global Health, Vol 7, Iss 12, Pp e1728-e1735 (2019)

Subject Terms: Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214109X19304255; https://doaj.org/toc/2214-109X

Access URL: https://doaj.org/article/7b6a61e9c70949f9a7638941c3cc314e

Strengthening the informed consent process in international health research through community engagement: The KEMRI-Wellcome Trust Research Programme Experience.

Authors: Mwanamvua Boga, Alun Davies, Dorcas Kamuya, Samson M Kinyanjui, Ester Kivaya, Francis Kombe, Trudie Lang, Vicki Marsh, Bibi Mbete, Albert Mlamba, Sassy Molyneux, Stephen Mulupi, Salim Mwalukore

Source: PLoS Medicine, Vol 8, Iss 9, p e1001089 (2011)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3172253?pdf=render; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/63be8538151b4c549fd3f5c338e5af6b