The widely used Ucp1-Cre transgene elicits complex developmental and metabolic phenotypes

Authors: Manasi Suchit Halurkar, Oto Inoue, Archana Singh, Rajib Mukherjee, Meghana Ginugu, Christopher Ahn, Christian Louis Bonatto Paese, Molly Duszynski, Samantha A. Brugmann, Hee-Woong Lim, Joan Sanchez-Gurmaches

Source: Nature Communications, Vol 16, Iss 1, Pp 1-16 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f3ddb238cc3344feadcfe3711a22da8d

A distant global control region is essential for normal expression of anterior HOXA genes during mouse and human craniofacial development

Authors: Andrea Wilderman, Eva D’haene, Machteld Baetens, Tara N. Yankee, Emma Wentworth Winchester, Nicole Glidden, Ellen Roets, Jo Van Dorpe, Sandra Janssens, Danny E. Miller, Miranda Galey, Kari M. Brown, Rolf W. Stottmann, Sarah Vergult, K. Nicole Weaver, Samantha A. Brugmann, Timothy C. Cox, Justin Cotney

Source: Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d8bfbb8f7d514cd7a8d154657d67b4ca

Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders

Authors: Luca Pagliaroli, Patrizia Porazzi, Alyxandra T. Curtis, Chiara Scopa, Harald M. M. Mikkers, Christian Freund, Lucia Daxinger, Sandra Deliard, Sarah A. Welsh, Sarah Offley, Connor A. Ott, Bruno Calabretta, Samantha A. Brugmann, Gijs W. E. Santen, Marco Trizzino

Source: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d81d9aec3d4b4606a4380fcc57816cd2

Pharmacological intervention of the FGF–PTH axis as a potential therapeutic for craniofacial ciliopathies

Authors: Christian Louis Bonatto Paese, Ching-Fang Chang, Daniela Kristeková, Samantha A. Brugmann

Source: Disease Models & Mechanisms, Vol 15, Iss 8 (2022)

Subject Terms: primary cilia, ciliopathies, fgf, c2cd3, micrognathia, talpid2, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/15/8/dmm049611; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

Access URL: https://doaj.org/article/abf3fe73d6d444b38e5f932bdb4f0016

Centriolar Protein C2cd3 Is Required for Craniofacial Development

Authors: Ching-Fang Chang, Kari M. Brown, Yanfen Yang, Samantha A. Brugmann

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: primary cilia, ciliopathies, C2cd3, craniofacial development, neural crest, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.647391/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/ef0edc0d6c854dd78c37a5f1efa9e6e8

Mutation in the Ciliary Protein C2CD3 Reveals Organ-Specific Mechanisms of Hedgehog Signal Transduction in Avian Embryos

Authors: Evan C. Brooks, Christian Louis Bonatto Paese, Anne H. Carroll, Jaime N. Struve, Nandor Nagy, Samantha A. Brugmann

Source: Journal of Developmental Biology, Vol 9, Iss 2, p 12 (2021)

Subject Terms: primary cilia, ciliopathies, Hedgehog signaling, talpid2, C2CD3, hindgut, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2221-3759/9/2/12; https://doaj.org/toc/2221-3759

Access URL: https://doaj.org/article/68242d13ae5240ee8eca9b26b38c7a5a

Using the avian mutant talpid2 as a disease model for understanding the oral-facial phenotypes of oral-facial-digital syndrome

Authors: Elizabeth N. Schock, Ching-Fang Chang, Jaime N. Struve, Ya-Ting Chang, Julie Chang, Mary E. Delany, Samantha A. Brugmann

Source: Disease Models & Mechanisms, Vol 8, Iss 8, Pp 855-866 (2015)

Subject Terms: Primary cilia, Craniofacial, Neural crest, talpid2, Ciliopathies, Chicken, Oral-facial-digital syndrome, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/8/8/855; https://doaj.org/toc/1754-8411; https://doaj.org/toc/1754-8403

Access URL: https://doaj.org/article/bb52940bf2d848878fcfbd1590fa2a1f

Stage‐dependent craniofacial defects resulting from Sprouty2 overexpression.

Authors: L. Henry Goodnough, Samantha A. Brugmann, Diane Hu, Jill A. Helms

Source: Developmental Dynamics; Jul2007, Vol. 236 Issue 7, p1918-1928, 11p

Subject Terms: SKULL abnormalities, PROTEIN-tyrosine kinases, FIBROBLAST growth factors, CHONDROGENESIS

Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks

Authors: Kelsey H Elliott, Xiaoting Chen, Joseph Salomone, Praneet Chaturvedi, Preston A Schultz, Sai K Balchand, Jeffrey D Servetas, Aimée Zuniga, Rolf Zeller, Brian Gebelein, Matthew T Weirauch, Kevin A Peterson, Samantha A Brugmann

Source: eLife, Vol 9 (2020)

Subject Terms: Gli transcription factors, Hand2, functional genomic, mandible, cis-regulatory modules, low affinity binding, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/56450; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/659f921a3e85487a949e94d7fb166cc9

A tissue-specific role for intraflagellar transport genes during craniofacial development.

Authors: Elizabeth N Schock, Jaime N Struve, Ching-Fang Chang, Trevor J Williams, John Snedeker, Aria C Attia, Rolf W Stottmann, Samantha A Brugmann

Source: PLoS ONE, Vol 12, Iss 3, p e0174206 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5367710?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/812c24cf00e7403e972be604bc294203

Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development.

Authors: John Snedeker, Elizabeth N Schock, Jamie N Struve, Ching-Fang Chang, Megan Cionni, Pamela V Tran, Samantha A Brugmann, Rolf W Stottmann

Source: PLoS ONE, Vol 12, Iss 3, p e0173258 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5349613?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/2df64b1f400d41e59e1bebc42567e1fd

Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline.

Authors: Ching-Fang Chang, Ya-Ting Chang, Grethel Millington, Samantha A Brugmann

Source: PLoS Genetics, Vol 12, Iss 11, p e1006351 (2016)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5089743?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/7e81d240408e4dbbac9c1f8ff09f6620

A cross-species analysis of microRNAs in the developing avian face.

Authors: Kara E Powder, Yuan-Chieh Ku, Samantha A Brugmann, Rose A Veile, Nicole A Renaud, Jill A Helms, Michael Lovett

Source: PLoS ONE, Vol 7, Iss 4, p e35111 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3327661?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cc928a63316f44f9a2d8c39886c3efda

Estrogen/estrogen receptor alpha signaling in mouse posterofrontal cranial suture fusion.

Authors: Aaron W James, Alexander A Theologis, Samantha A Brugmann, Yue Xu, Antoine L Carre, Philipp Leucht, Katherine Hamilton, Kenneth S Korach, Michael T Longaker

Source: PLoS ONE, Vol 4, Iss 9, p e7120 (2009)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2743190?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ee7e9dd23dc649b0b24489e0e6042a0d