Pharmacologic inhibition of dipeptidyl peptidase 1 (cathepsin C) does not block in vitro granzyme-mediated target cell killing by CD8 T or NK cells

Authors: Vivien R. Sutton, Sally V. Watt, Hedieh Akhlaghi, David C. Cipolla, Kuan-Ju Chen, Daniel LaSala, Patrick P. McDonald, Paul A. Beavis, Isabelle Munoz, Adrian W. Hodel, Tahereh Noori, Ilia Voskoboinik, Joseph A. Trapani

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: DPP1, granzyme, apoptosis, serine protease, T cell, lysosome, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1396710/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/637ceae3f9ef4a27add5a0ac7f8e1bc1