Randomized phase 2 study to assess the role of single-agent nivolumab to maintain remission in acute myeloid leukemia

Authors: Pyzer, Athalia R. ¹, Dillon, Laura W. ², Sharon, Elad ³, Karrison, Theodore G. ⁴, Zha, Yuanyuan ¹, Fulton, Noreen ¹, Gui, Gege ^{2, 5}, Andrew, Georgia ², Streicher, Howard ³, Sweet, Kendra ⁶, Yaghmour, George ⁷, Liu, Jane Jijun ⁸, Jonas, Brian A. ⁹, Schimmer, Aaron D. ¹⁰, Grant, Steven ¹¹, Zeidan, Amer M. ¹², Hildebrandt, Gerhard C. ¹³, Lowrey, Christopher H. ¹⁴, Mattison, Ryan J. ¹⁵, Palmisiano, Neil ¹⁶, Salhotra, Amandeep ¹⁷, Tzachanis, Dimitrios ¹⁸, Baer, Maria R. ¹⁹, Lin, Tara L. ²⁰, Patel, Prapti ²¹, Chen, Helen ³, Stadler, Walter M. ¹, Odenike, Olatoyosi ¹, Larson, Richard A. ¹, Gajewski, Thomas F. ²², Hourigan, Christopher S. ^{2, 5}, Stock, Wendy ¹, Liu, Hongtao ^{1, 23, ∗}

Source: In Blood Advances December 2024

TP53 mutations are associated with CD19− relapse and inferior outcomes after blinatumomab in adults with ALL

Authors: Aldoss, Ibrahim ^{1, ∗}, Li, Shanpeng ², Zhang, Jianying ², Clark, Mary C. ¹, Agrawal, Vaibhav ¹, Pourhassan, Hoda ¹, Koller, Paul ¹, Aribi, Ahmed ¹, Ali, Haris ¹, Blackmon, Amanda ¹, Otoukesh, Salman ¹, Sandhu, Karamjeet ¹, Ball, Brian ¹, Arslan, Shukaib ¹, Artz, Andrew ¹, Amanam, Idoroenyi ¹, Al Malki, Monzr M. ¹, Salhotra, Amandeep ¹, Kovacsovics, Tibor ³, Murphy, Lindsey ⁴, Afkhami, Michelle ⁵, Ngo, Dat ⁶, Tinajero, Jose ⁶, Gu, Zhaohui ², Becker, Pamela S. ¹, Nakamura, Ryotaro ¹, Stein, Anthony ¹, Marcucci, Guido ¹, Forman, Stephen J. ¹, Pullarkat, Vinod ¹

Source: In Blood Advances December 2024

Impact of spliceosome mutation on outcomes of myelodysplastic syndrome and chronic myelomonocytic leukemia patients undergoing allogeneic hematopoietic cell transplantation

Authors: Desai, Amrita, Samara, Yazeed, Yang, Dongyun, Ball, Brian, Braun, Adam, Koller, Paul, Blackmon, Amanda, Agrawal, Vaibhav, Pourhassan, Hoda, Amanam, Idoroenyi, Arslan, Shukaib, Otoukesh, Salman, Sandhu, Karamjeet, Aldoss, Ibrahim, Ali, Haris, Salhotra, Amandeep, Al Malki, Monzr M., Artz, Andrew, Becker, Pamela, Smith, Eileen, Stein, Anthony, Marcucci, Guido, Forman, Stephen J., Curtin, Peter, Nakamura, Ryotaro, Pullarkat, Vinod

Source: In Leukemia Research October 2024 145

Yttrium-90 anti-CD25 BEAM conditioning for autologous hematopoietic cell transplantation in Peripheral T-cell lymphoma

Authors: Zain, Jasmine, Tsai, Ni-Chun, Palmer, Joycelynne, Simpson, Jennifer, Adhikarla, Vikram, Bading, James R., Yazaki, Paul, Smith, Eileen P., Dandapani, Savita, Song, Joo Y., Karras, Nicole A., Herrera, Alex F., Salhotra, Amandeep, Nademanee, Auayporn P., Nakamura, Ryotaro, Smith, D. Lynne, Yamauchi, David, Poku, Erasmus K., Biglang-Awa, V. Eric, Colcher, David, Shively, John E., Wu, Anna M., Forman, Stephen J., Wong, Jeffrey, Thomas, Sandra

Source: In Blood Advances 24 September 2024 8(18):4812-4822

Use of monoclonal antibody therapy in hematologic patients with mild‐to‐moderate COVID‐19: A retrospective single‐center experience

Authors: Amanam, Idoroenyi, Yao, Janny, Puing, Alfredo, Tsai, Ni‐Chun, Samuels, Diana, Ngo, Dat, Ho, Stephanie, Ali, Haris, Aribi, Ahmed, Arslan, Shukaib, Artz, Andrew, Htut, Myo, Koller, Paul, Salhotra, Amandeep, Sandhu, Karamjeet, Nikolaenko, Liana, Pawlowska, Anna, Shouse, Geoffrey, Stein, Anthony, Marcucci, Guido, Forman, Stephen, Nakamura, Ryotaro, Dadwal, Sanjeet, Al Malki, Monzr M.

Source: Cancer medicine. 12(10):11248-11253

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194556110.0x000001&indx=1&recIds=ETOCvdc_100194556110.0x000001

Post-Transplantation Sinusoidal Obstruction Syndrome in Adult Patients with B Cell Acute Lymphoblastic Leukemia Treated with Pretransplantation Inotuzumab

Authors: Agrawal, Vaibhav, Pourhassan, Hoda, Tsai, Ni-Chun, Ngo, Dat, Koller, Paul, Malki, Monzr M. Al, Salhotra, Amandeep, Ali, Haris, Aribi, Ahmed, Sandhu, Karamjeet S., Arslan, Shukaib, Ball, Brian, Otoukesh, Salman, Amanam, Idoroenyi, Artz, Andrew, Singh, Dupinder, Becker, Pamela S., Stewart, Forrest M., Smith, Eileen P., Curtin, Peter, Stein, Anthony S., Marcucci, Guido, Forman, Stephen J., Nakamura, Ryotaro, Pullarkat, Vinod, Aldoss, Ibrahim

Source: Transplantation and Cellular Therapy. 29(5):314-320

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191869847.0x000001&indx=1&recIds=ETOCvdc_100191869847.0x000001

Axatilimab for Chronic Graft-Versus-Host Disease After Failure of at Least Two Prior Systemic Therapies: Results of a Phase I/II Study

Authors: Kitko, Carrie L., Arora, Mukta, DeFilipp, Zachariah, Zaid, Mohammad Abu, Di Stasi, Antonio, Radojcic, Vedran, Betts, Courtney B., Coussens, Lisa M., Meyers, Michael L., Qamoos, Hope, Ordentlich, Peter, Kumar, Vinit, Quaranto, Christine, Schmitt, Aaron, Gu, Yu, Blazar, Bruce R., Wang, Trent P., Salhotra, Amandeep, Pusic, Iskra, Jagasia, Madan, Lee, Stephanie J.

Source: Journal of clinical oncology. 41(10):1864-1875

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191315977.0x000001&indx=1&recIds=ETOCvdc_100191315977.0x000001

High response rates and transition to transplant after novel targeted and cellular therapies in adults with relapsed/refractory acute lymphoblastic leukemia with Philadelphia‐like fusions

Authors: Aldoss, Ibrahim, Afkhami, Michelle, Yang, Dongyun, Gu, Zhaohui, Mokhtari, Sally, Shahani, Shilpa, Pourhassan, Hoda, Agrawal, Vaibhav, Koller, Paul, Arslan, Shukaib, Tomasian, Vanina, Al Malki, Monzr M., Artz, Andrew, Salhotra, Amandeep, Ali, Haris, Aribi, Ahmed, Sandhu, Karamjeet S., Ball, Brian, Otoukesh, Salman, Amanam, Idoroenyi, Becker, Pamela S., Stewart, Forrest M., Curtin, Peter, Smith, Eileen, Telatar, Milhan, Stein, Anthony S., Marcucci, Guido, Forman, Stephen J., Nakamura, Ryotaro, Pullarkat, Vinod

Source: American journal of hematology. 98(6):848-856

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182457993.0x000001&indx=1&recIds=ETOCvdc_100182457993.0x000001

A critical review of belumosudil in adult and pediatric patients with chronic graft-versus-host disease

Authors: Salhotra, Amandeep, Sandhu, Karamjeet, O'Hearn, James, Ali, Haris, Nakamura, Ryotaro, Modi, Badri G

Source: Expert review of clinical immunology. 19(3):241-251

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175109938.0x000001&indx=1&recIds=ETOCvdc_100175109938.0x000001

Total Body Irradiation and Fludarabine with Post-Transplantation Cyclophosphamide for Mismatched Related or Unrelated Donor Hematopoietic Cell Transplantation

Authors: Arslan, Shukaib, Desai, Amrita, Yang, Dongyun, Mokhtari, Sally, Tiemann, Katrin, Otoukesh, Salman, Samara, Yazeed, Blackmon, Amanda, Agrawal, Vaibhav, Pourhassan, Hoda, Amanam, Idoroenyi, Ball, Brian, Koller, Paul, Salhotra, Amandeep, Aribi, Ahmed, Becker, Pamela, Curtin, Peter, Artz, Andrew, Aldoss, Ibrahim, Ali, Haris, Stewart, Forrest, Smith, Eileen, Stein, Anthony, Marcucci, Guido, Forman, Stephen J., Nakamura, Ryotaro, Al Malki, Monzr M.

Source: In Transplantation and Cellular Therapy October 2024 30(10):1013-1013

Trafficking between clonally related peripheral T-helper cells and tissue-resident T-helper cells in chronic GVHD

Authors: Kong, Xiaohui, Wu, Xiwei, Wang, Bixin, Zeng, Deye, Cassady, Kaniel, Nasri, Ubaydah, Zheng, Moqian, Wu, Alyssa, Qin, Hanjun, Tsai, Weimin, Salhotra, Amandeep, Nakamura, Ryotaro, Martin, Paul J., Zeng, Defu ^∗

Source: In Blood 22 December 2022 140(25):2740-2753

PD-1 Blockade After Avelumab in Relapsed/Refractory Classical Hodgkin Lymphoma

Authors: Thiruvengadam, Swetha Kambhampati, Mei, Matthew G., Godfrey, James, Siddiqi, Tanya, Salhotra, Amandeep, Chen, Robert, Smith, Eileen, Popplewell, Leslie L., Herrera, Alex F.

Source: In Clinical Lymphoma, Myeloma and Leukemia October 2022 22(10):e893-e897

Report of four acute myeloid leukemia patients with sustained complete remission with less frequent administration of decitabine and venetoclax

Authors: Aribi, Ahmed, Salhotra, Amandeep, Ball, Brian, Stein, Anthony, Marcucci, Guido, Pullarkat, Vinod

Source: Leukemia & lymphoma. 64(4):897-899

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179650121.0x000001&indx=1&recIds=ETOCvdc_100179650121.0x000001

The feasibility of additional CD19‐targeted cellular therapy in relapsed/refractory B‐ALL with re‐emergence of CD19 antigen after prior CD19‐negative relapse

Authors: Agrawal, Vaibhav, Salhotra, Amandeep, Song, Joo, Gu, Zhaohui, Stein, Anthony S., Marcucci, Guido, Forman, Stephen J., Pullarkat, Vinod, Aldoss, Ibrahim

Source: American journal of hematology. 98(2):E38-E40

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100170804004.0x000001&indx=1&recIds=ETOCvdc_100170804004.0x000001

Extramedullary disease relapse and progression after blinatumomab therapy for treatment of acute lymphoblastic leukemia

Authors: Aldoss, Ibrahim, Otoukesh, Salman, Zhang, Jianying, Mokhtari, Sally, Ngo, Dat, Mojtahedzadeh, Mona, Al Malki, Monzr M., Salhotra, Amandeep, Ali, Haris, Aribi, Ahmed, Sandhu, Karamjeet S., Arslan, Shukaib, Koller, Paul, Ball, Brian, Stewart, Forrest, Curtin, Peter, Artz, Andrew, Nakamura, Ryotaro, Marcucci, Guido, Forman, Stephen J., Stein, Anthony S., Pullarkat, Vinod

Source: Cancer. 128(3):529-535

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142040528.0x000001&indx=1&recIds=ETOCvdc_100142040528.0x000001

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade

Authors: Wang, Hanying, He, Xin, Zhang, Lei, Dong, Haojie, Huang, Feiteng, Xian, Jie, Li, Min, Chen, Wei, Lu, Xiyuan, Pathak, Khyatiben V., Huang, Wenfeng, Li, Zheng, Zhang, Lianjun, Nguyen, Le Xuan Truong, Yang, Lu, Feng, Lifeng, Gordon, David J., Zhang, Jing, Pirrotte, Patrick, Chen, Chun-Wei, Salhotra, Amandeep, Kuo, Ya-Huei, Horne, David, Marcucci, Guido, Sykes, David B., Tiziani, Stefano, Jin, Hongchuan, Wang, Xian, Li, Ling

Source: Blood. 139(26):3752-3770

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183245126.0x000001&indx=1&recIds=ETOCvdc_100183245126.0x000001

PD-1 Blockade After Avelumab in Relapsed/Refractory Classical Hodgkin Lymphoma

Authors: Kambhampati, Swetha, Mei, Matthew G., Godfrey, James, Siddiqi, Tanya, Salhotra, Amandeep, Chen, Robert, Smith, Eileen, Popplewell, Leslie L., Herrera, Alex F.

Source: Clinical lymphoma, myeloma & leukemia. 22(10):e893-e897

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100170277050.0x000001&indx=1&recIds=ETOCvdc_100170277050.0x000001

Clinical experience with venetoclax and hypomethylating agents (HMA) in patients with newly diagnosed and relapsed or refractory KMT2A-Rearranged acute myeloid leukemia (AML)

Authors: Ball, Brian J., Arslan, Shukaib, Koller, Paul, Ngo, Dat, Afkhami, Michelle, Salhotra, Amandeep, Al-Malki, Monzr, Aribi, Ahmed, Ali, Haris, Sandhu, Karamjeet, Otoukesh, Salman, Amanam, Idoroenyi, Pourhassan, Hoda, Artz, Andrew, Curtin, Peter, Stein, Anthony, Nakamura, Ryotaro, Marcucci, Guido, Smith, Eileen, Pullarkat, Vinod, Aldoss, Ibrahim

Source: Leukemia & lymphoma. 63(13):3232-3236

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168730383.0x000001&indx=1&recIds=ETOCvdc_100168730383.0x000001

Long-term follow-up of patients with poor-risk acute leukemia treated on a phase 2 trial undergoing intensified conditioning regimen prior to allogeneic hematopoietic cell transplantation

Authors: Salhotra, Amandeep, Yang, Dongyun, Mokhtari, Sally, Hui, Susanta, Al Malki, Monzr M., Armenian, Saro, Sigala, Brianna, Aldoss, Ibrahim, Pullarkat, Vinod, Forman, Stephen, Marcucci, Guido, Nakamura, Ryotaro, Artz, Andrew, Wong, Jeffery, Stein, Anthony

Source: Leukemia & lymphoma. 63(5):1220-1226

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154920078.0x000001&indx=1&recIds=ETOCvdc_100154920078.0x000001

Venetoclax and hypomethylating agents yield high response rates and favourable transplant outcomes in patients with newly diagnosed acute myeloid leukaemia

Authors: Salhotra, Amandeep, Tsai, Ni‐Chun, Zhang, Jianying, Ngo, Dat, Aribi, Ahmed, Sandhu, Karamjeet, Ball, Brian, Al‐Malki, Monzr, Ali, Haris, Koller, Paul, Artz, Andrew, Forman, Stephen, Nakamura, Ryotaro, Stein, Anthony, Marcucci, Guido, Aldoss, Ibrahim, Pullarkat, Vinod

Source: British journal of haematology. 196(6):e71-e74

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144182547.0x000001&indx=1&recIds=ETOCvdc_100144182547.0x000001