Real-world trough concentrations and effectiveness of long-acting cabotegravir and rilpivirine: a multicenter prospective observational study in Switzerland

Authors: Abela, I, Aebi-Popp, K, Anagnostopoulos, A, Battegay, M, Bernasconi, E, Braun, DL, Bucher, HC, Calmy, A, Cavassini, M, Ciuffi, A, Dollenmaier, G, Egger, M, Elzi, L, Fehr, J, Fellay, J, Furrer, H, Fux, CA, Günthard, HF, Hachfeld, A, Haerry, D, Hasse, B, Hirsch, HH, Hoffmann, M, Hösli, I, Huber, M, Jackson-Perry, D, Kahlert, CR, Kaiser, L, Keiser, O, Klimkait, T, Kouyos, RD, Kovari, H, Kusejko, K, Labhardt, N, Leuzinger, K, Martinez de Tejada, B, Marzolini, C, Metzner, KJ, Müller, N, Nemeth, J, Nicca, D, Notter, J, Paioni, P, Pantaleo, G, Perreau, M, Rauch, A, Salazar-Vizcaya, L, Schmid, P, Speck, R, Stöckle, M, Tarr, P, Trkola, A, Wandeler, G, Weisser, M, Yerly, S, Thoueille, Paul, Saldanha, Susana Alves, Schaller, Fabian, Choong, Eva, Munting, Aline, Cavassini, Matthias, Braun, Dominique, Günthard, Huldrych F., Kusejko, Katharina, Surial, Bernard, Furrer, Hansjakob, Rauch, Andri, Rougemont, Mathieu, Ustero, Pilar, Calmy, Alexandra, Stöckle, Marcel, Marzolini, Catia, Di Benedetto, Caroline, Bernasconi, Enos, Schmid, Patrick, Piso, Rein Jan, Andre, Pascal, Girardin, François R., Guidi, Monia, Buclin, Thierry, Decosterd, Laurent A.

Source: In The Lancet Regional Health - Europe January 2024 36

Population pharmacokinetics of rilpivirine following oral administration and long-acting intramuscular injection in real-world people with HIV.

Authors: Thoueille, Paul, Saldanha, Susana Alves, Schaller, Fabian, Choong, Eva, Veuve, François, Munting, Aline, Cavassini, Matthias, Braun, Dominique, Günthard, Huldrych F., Duran Ramirez, Jessy J., Surial, Bernard, Furrer, Hansjakob, Rauch, Andri, Ustero, Pilar, Calmy, Alexandra, Stöckle, Marcel, Di Benedetto, Caroline, Bernasconi, Enos, Schmid, Patrick, Marzolini, Catia

Source: Frontiers in Pharmacology; 2024, p1-11, 11p

Subject Terms: ORAL drug administration, CLINICAL trials, INTRAMUSCULAR injections, HIV-positive persons, PHARMACOKINETICS

Population Pharmacokinetics of Cabotegravir Following Oral Administration and Long‐Acting Intramuscular Injection in Real‐World People with HIV.

Authors: Thoueille, Paul, Saldanha, Susana Alves, Schaller, Fabian, Choong, Eva, Veuve, François, Munting, Aline, Cavassini, Matthias, Braun, Dominique, Günthard, Huldrych F., Duran Ramirez, Jessy J., Surial, Bernard, Furrer, Hansjakob, Rauch, Andri, Ustero, Pilar, Calmy, Alexandra, Stöckle, Marcel, Di Benedetto, Caroline, Bernasconi, Enos, Schmid, Patrick, Marzolini, Catia

Source: Clinical Pharmacology & Therapeutics; Jun2024, Vol. 115 Issue 6, p1450-1459, 10p

Subject Terms: ORAL drug administration, INTRAMUSCULAR injections, HIV-positive persons, PHARMACOKINETICS, BODY mass index

Population pharmacokinetic modelling to characterize the effect of chronic kidney disease on tenofovir exposure after tenofovir alafenamide administration.

Authors: Thoueille, Paul¹ (AUTHOR), Saldanha, Susana Alves¹ (AUTHOR), Desfontaine, Vincent¹ (AUTHOR), Kusejko, Katharina^2,3 (AUTHOR), Courlet, Perrine¹ (AUTHOR), Andre, Pascal¹ (AUTHOR), Cavassini, Matthias⁴ (AUTHOR), Decosterd, Laurent A¹ (AUTHOR), Buclin, Thierry¹ (AUTHOR), Guidi, Monia^1,5,6 (AUTHOR) Monia.Guidi@chuv.ch, Study, the Swiss HIV Cohort (AUTHOR)

Source: Journal of Antimicrobial Chemotherapy (JAC). Jun2023, Vol. 78 Issue 6, p1433-1443. 11p.

Subject Terms: *CHRONIC kidney failure, *CREATININE, *TENOFOVIR, *HIV prevention, *HIV-positive persons, *PHARMACOKINETICS

Transfer of antiretroviral drugs into breastmilk: a prospective study from the Swiss Mother and Child HIV Cohort Study.

Authors: Aebi-Popp, Karoline, Kahlert, Christian R, Crisinel, Pierre-Alex, Decosterd, Laurent, Saldanha, Susana Alves, Hoesli, Irene, Tejada, Begona Martinez De, Duppenthaler, Andrea, Rauch, Andri, Marzolini, Catia, (SHCS), Swiss Mother and Child HIV Cohort Study, Martinez De Tejada, Begona, Swiss Mother and Child HIV Cohort Study (SHCS)

Source: Journal of Antimicrobial Chemotherapy (JAC); Dec2022, Vol. 77 Issue 12, p3436-3442, 7p

Subject Terms: ANTI-HIV agents, MOTHERS, BREAST milk, BLOOD plasma, ANTIRETROVIRAL agents, BREASTFEEDING, RITONAVIR, QUESTIONNAIRES, RESEARCH funding, SWISS, LONGITUDINAL method

Geographic Terms: SWITZERLAND

Real-life management of drug-drug interactions between antiretrovirals and statins.

Authors: Courlet, Perrine, Livio, Françoise, Saldanha, Susana Alves, Scherrer, Alexandra, Battegay, Manuel, Cavassini, Matthias, Stoeckle, Marcel, Decosterd, Laurent Arthur, Marzolini, Catia, Study, the Swiss HIV Cohort, Alves Saldanha, Susana, Swiss HIV Cohort Study

Source: Journal of Antimicrobial Chemotherapy (JAC); Jul2020, Vol. 75 Issue 7, p1972-1980, 9p

Subject Terms: HIV infections, RESEARCH, ANTILIPEMIC agents, HETEROCYCLIC compounds, RESEARCH methodology, MEDICAL cooperation, EVALUATION research, COMPARATIVE studies, DRUGS, DRUG interactions, FLUOROHYDROCARBONS, LONGITUDINAL method

Aging does not impact drug--drug interaction magnitudes with antiretrovirals.

Authors: Stader, Felix, Decosterd, Laurent, Stoeckle, Marcel, Cavassini, Matthias, Battegay, Manuel, Alves Saldanha, Susana, Marzolini, Catia, Courlet, Perrine, Saldanha, Susana Alves, and the Swiss HIV Cohort Study, the Swiss HIV Cohort Study*

Source: AIDS (02699370); May2020, Vol. 34 Issue 6, p949-952, 4p

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Emtricitabine and lamivudine concentrations in saliva: a simple suitable test for treatment adherence.

Authors: Courlet, Perrine, Decosterd, Laurent Arthur, Brown, Jennifer Anne, Saldanha, Susana Alves, Marzolini, Catia, Cavassini, Matthias, Stoeckle, Marcel, Csajka, Chantal, Labhardt, Niklaus Daniel, Calmy, Alexandra, Study, Swiss HIV Cohort, Alves Saldanha, Susana, Swiss HIV Cohort Study

Source: Journal of Antimicrobial Chemotherapy (JAC); Aug2019, Vol. 74 Issue 8, p2468-2470, 3p

Subject Terms: SALIVA, THERAPEUTICS, HIV infections

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Polypharmacy, Drug–Drug Interactions, and Inappropriate Drugs: New Challenges in the Aging Population With HIV.

Authors: Courlet, Perrine, Livio, Françoise, Guidi, Monia, Cavassini, Matthias, Battegay, Manuel, Stoeckle, Marcel, Buclin, Thierry, Saldanha, Susana Alves, Csajka, Chantal, Marzolini, Catia, Decosterd, Laurent, Study, Swiss HIV Cohort

Source: Open Forum Infectious Diseases; Dec2019, Vol. 6 Issue 12, pN.PAG-N.PAG, 1p

Subject Terms: POPULATION aging, POLYPHARMACY, OLDER people, CARDIOVASCULAR agents, HIV infections

Geographic Terms: LIVERPOOL (England)

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