Empagliflozin Decreases Lactate Generation in an NHE-1 Dependent Fashion and Increases α-Ketoglutarate Synthesis From Palmitate in Type II Diabetic Mouse Hearts

Authors: Hong Zhang, Laween Uthman, Diane Bakker, Sahinda Sari, Sha Chen, Markus W. Hollmann, Ruben Coronel, Nina C. Weber, Sander M. Houten, Michel van Weeghel, Coert J. Zuurbier

Source: Frontiers in Cardiovascular Medicine, Vol 7 (2020)

Subject Terms: SGLT2, glycolysis, glucose oxidation, fatty acid oxidation, NHE, diastolic function, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2020.592233/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/908a771a40ff4285a5ac4f1f00cafc9b