High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against nontuberculous mycobacteria in vitro and in vivo

Authors: Ragunathan, Priya, Sae-Lao, Patcharaporn, Hamela, Claire, Alcaraz, Matthéo, Krah, Alexander, Poh, Wee Han, Ern Pee, Carmen Jia, Hou Lim, Albert Yick, Rice, Scott A., Pethe, Kevin, Bond, Peter J., Dick, Thomas, Kremer, Laurent, Bates, Roderick W., Grüber, Gerhard

Source: In Journal of Biological Chemistry February 2024 300(2)

Confirmation of the structure of (±)-preisomide by total synthesisElectronic supplementary information (ESI) available. CCDC 2292753. For ESI and crystallographic data in CIF or other electronic format see DOI: https://doi.org/10.1039/d3ob01250f

Authors: Teo, Hong Kang, Sae-Lao, Patcharaporn, Bates, Roderick W.

Source: Organic & biomolecular chemistry. 21(39):7954-7959

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195404340.0x000001&indx=1&recIds=ETOCvdc_100195404340.0x000001

SQ31f is a potent non-tuberculous mycobacteria antibiotic by specifically targeting the mycobacterial F-ATP synthase.

Authors: Ragunathan, Priya¹ (AUTHOR), Sae-Lao, Patcharaporn² (AUTHOR), Harikishore, Amaravadhi^1,2 (AUTHOR), Daher, Wassim^3,4 (AUTHOR), Roquet-Banères, Françoise³ (AUTHOR), Kremer, Laurent^3,4 (AUTHOR), Bates, Roderick W² (AUTHOR), Grüber, Gerhard^1,5 (AUTHOR)

Source: Journal of Antimicrobial Chemotherapy (JAC). Jan2025, Vol. 80 Issue 1, p270-280. 11p.

Subject Terms: *DRUG tolerance, *DRUG additives, *OXYGEN consumption, *PHARMACODYNAMICS, *MYCOBACTERIUM

Chapter One - Hydroxylamine natural products

Authors: Bates, Roderick W. ^⁎, Pham, Thang Loi, Sae-Lao, Patcharaporn

Source: In The Aklaloids 2025 93:1-172

Discovery of a Novel Mycobacterial F‐ATP Synthase Inhibitor and its Potency in Combination with Diarylquinolines

Authors: Hotra, Adam, Ragunathan, Priya, Ng, Pearly Shuyi, Seankongsuk, Pattarakiat, Harikishore, Amaravadhi, Sarathy, Jickky Palmae, Saw, Wuan‐Geok, Lakshmanan, Umayal, Sae‐Lao, Patcharaporn, Kalia, Nitin Pal, Shin, Joon, Kalyanasundaram, Revathy, Anbarasu, Sivaraj, Parthasarathy, Krupakar, Pradeep, Chaudhari Namrata, Makhija, Harshyaa, Dröge, Peter, Poulsen, Anders, Tan, Jocelyn Hui Ling, Pethe, Kevin, Dick, Thomas, Bates, Roderick W., Grüber, Gerhard

Source: Angewandte Chemie. 132(32):13397-13406

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114109520.0x000001&indx=1&recIds=ETOCvdc_100114109520.0x000001

Highly potent anti-NTM inhibitors targeting the oxidative phosphorylation pathway of a broad spectrum of non-tuberculous mycobacterial pathogens

Authors: Ragunathan, Priya, Sae-Lao, Patcharaporn, Harikishore, Amaravadhi, Krah, Alexander, Dick, Thomas, Kremer, Laurent, Bates, Roderick W., Grüber, Gerhard

Source: In BBA - Bioenergetics 1 September 2024 1865 Supplement

The Total Synthesis of Raistrickindole A.

Authors: Pham, Thang Loi, Sae-Lao, Patcharaporn, Toh, Hannah Hui Min, Csókás, Dániel, Bates, Roderick W.

Source: Journal of Organic Chemistry; 12/2/2022, Vol. 87 Issue 23, p16111-16114, 4p

This result is not displayed to guests.
Login for full access.

Total synthesis of racemosol and de- O-methylracemosol, potent cyclooxygenase (COX) inhibitors and antimalarial agents

Authors: Sae-Lao, Patcharaporn, Kittakoop, Prasat, Rajviroongit, Shuleewan

Source: In Tetrahedron Letters 2006 47(3):345-348

ChemInform Abstract: A Total Synthesis of (+)-Negamycin Through Isoxazolidine Allylation.

Authors: Bates, Roderick W., Khanizeman, Rab'iah Nisha, Hirao, Hajime, Tay, Yu Shan, Sae‐Lao, Patcharaporn

Source: ChemInform; Dec2014, Vol. 45 Issue 50, pno-no, 1p

Total Synthesis of Racemosol and De‐O‐methylracemosol, Potent Cyclooxygenase (COX) Inhibitors and Antimalarial Agents.

Authors: Sae‐Lao, Patcharaporn, Kittakoop, Prasat, Rajviroongit, Shuleewan

Source: ChemInform; April 2006, Vol. 37 Issue: 17 pno-no