A Repurposed Drug Selection Pipeline to Identify CNS-Penetrant Drug Candidates for Glioblastoma.

Authors: Ntafoulis, Ioannis, Koolen, Stijn L. W., van Tellingen, Olaf, den Hollander, Chelsea W. J., Sabel-Goedknegt, Hendrika, Dijkhuizen, Stephanie, Haeck, Joost, Reuvers, Thom G. A., de Bruijn, Peter, van den Bosch, Thierry P. P., van Dis, Vera, Gao, Zhenyu, Dirven, Clemens M. F., Leenstra, Sieger, Lamfers, Martine L. M.

Source: Pharmaceuticals (14248247); Dec2024, Vol. 17 Issue 12, p1687, 16p

Subject Terms: ATP-binding cassette transporters, BRAIN tumors, CENTRAL nervous system, BRAIN cancer, DATA integrity, BLOOD-brain barrier