Engineered protein subunit COVID19 vaccine is as immunogenic as nanoparticles in mouse and hamster models

Authors: Melissa M. Matthews, Tae Gyun Kim, Keon Young Kim, Vladimir Meshcheryakov, Higor Alves Iha, Miho Tamai, Daiki Sasaki, Paola Laurino, Saacnicteh Toledo-Patiño, Mary Collins, Tzung-Yang Hsieh, Satoshi Shibata, Noriko Shibata, Fumiko Obata, Jun Fujii, Toshihiro Ito, Hiroshi Ito, Hiroki Ishikawa, Matthias Wolf

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Subject Terms: Protein subunit vaccine, Protein engineering, Scaffold, Adjuvant, Nanoparticle, SARS-CoV-2 (CoV-2) spike protein, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0177c76b3d834a7fb816ba77c81efaed

Implications of divergence of methionine adenosyltransferase in archaea

Authors: Bhanu Pratap Singh Chouhan, Madhuri Gade, Desirae Martinez, Saacnicteh Toledo‐Patino, Paola Laurino

Source: FEBS Open Bio, Vol 12, Iss 1, Pp 130-145 (2022)

Subject Terms: ancestral sequence reconstruction, catalytic interface, divergence, enzyme evolution, methionine adenosyltransferase, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2211-5463

Access URL: https://doaj.org/article/0442df84847c4cd681036442ebe4ccb9