Identification of a novel subtype of SPP1 + macrophages expressing SIRPα: implications for tumor immune evasion and treatment response prediction

Authors: Kun Chen, Yida Li, Jianjiao Ni, Xi Yang, Yue Zhou, Yechun Pang, Ruiting Ye, Hongru Chen, Silai Yu, Peng Wang, Zhengfei Zhu

Source: Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-17 (2024)

Subject Terms: Esophageal squamous cell carcinoma, SPP1 + macrophages, SIRPα, Tumor microenvironment, Immunotherapy, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3619

Access URL: https://doaj.org/article/95bf799f4e1f4f7d98fff138b882d378

SPP1+ macrophages promote head and neck squamous cell carcinoma progression by secreting TNF-α and IL-1β

Authors: Chun Liu, Kun Wu, Chuwen Li, Zhen Zhang, Peisong Zhai, Haiyan Guo, Jianjun Zhang

Source: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)

Subject Terms: Macrophages, Single-cell RNA sequencing, SPP1 + macrophages, TNF-α, IL-1β, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/4fa035b310ca40b4b516f4ec9911b00f

A comprehensive single-cell RNA transcriptomic analysis identifies a unique SPP1+ macrophages subgroup in aging skeletal muscle

Authors: Wen Bi, Mengyue Yang, Mengjia Shi, Mirong Hou, Changqing Jiang, Gang Fan, Weiming Guo

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Subject Terms: Single-cell sequencing, Skeletal muscle, SPP1+ macrophages, Cell senescence, Senolytics, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/f497b6263b3d41ea86f3f035dbb6865f

SPP1+ macrophages in colorectal cancer: Markers of malignancy and promising therapeutic targets

Authors: Zhenyu Xie, Gaozan Zheng, Liaoran Niu, Kunli Du, Ruikai Li, Hanjun Dan, Lili Duan, Hongze Wu, Guangming Ren, Xinyu Dou, Songchen Dai, Fan Feng, Jian Zhang, Jianyong Zheng

Source: Genes and Diseases, Vol 12, Iss 3, Pp 101340- (2025)

Subject Terms: Colorectal cancer, Immunotherapy, Single-cell RNA sequencing, Spatial transcriptomics, SPP1+macrophages, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304224001375; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/d744d38614ce4dd28a0e04c68e232561

Single-cell transcriptome analysis reveals status changes of immune cells in chronic kidney disease

Authors: Xinhuan Fan, Yuxin Zhu, Hao Kan, Aiqin Mao, Li Geng, Changzhu Li, Ka Zhang

Source: Frontiers in Medicine, Vol 11 (2024)

Subject Terms: human kidney, CKD, scRNA-seq, immune cell, SPP1 macrophages, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2024.1434535/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/9a8e60db504945bba40d7c3b43c4a06c

Single-cell RNA sequencing reveals intratumoral heterogeneity and multicellular community in primary hepatocellular carcinoma underlying microvascular invasionKey FindingsImplications

Authors: Zhuoya Sun, Biao Gao, Lai Song, Biying Wang, Junfeng Li, Hao Jiang, Xuerui Li, Yang Yu, Zishan Zhou, Zizhong Yang, Xiaohui Sun, Tianyu Jiao, Xiao Zhao, Shichun Lu, Shunchang Jiao

Source: Heliyon, Vol 10, Iss 18, Pp e37233- (2024)

Subject Terms: Hepatocellular carcinoma, Single-cell RNA sequencing, Microvascular invasion, SPP1+ macrophages, Proliferative CD4+ T cell population, Immunotherapy, Science (General), Q1-390, Social sciences (General), H1-99

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Relation: http://www.sciencedirect.com/science/article/pii/S2405844024132641; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/fe29fd74fd58439b8ade1976378c7a38

Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages

Authors: Tingting Chen, Jiayu Guo, Liqiang Ai, Yuquan Wang, Yan Wang, Bo Chen, Mingyue Liu, Shuping Zhuang, Kaidong Liu, Zhangxiang Zhao, Haihai Liang, Yunyan Gu

Source: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5751-5764 (2023)

Subject Terms: Idiopathic pulmonary fibrosis, Single-cell RNA-seq, Lung cancer, SPP1+ macrophages, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037023004348; https://doaj.org/toc/2001-0370

Access URL: https://doaj.org/article/6580b6f319314e7a84dc55f05551bc3d

The single-cell landscape of cystic echinococcosis in different stages provided insights into endothelial and immune cell heterogeneity

Authors: Xiaofeng Jiang, Xiaofan Zhang, Nan Jiang, Yeting Sun, Teng Li, Jing Zhang, Yujuan Shen, Jianping Cao

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: cystic echinococcosis, single-cell sequencing, immune cells, SPP1+ macrophages, Echinococcus granulosus, angiogenesis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1067338/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/387c662d7e834135bedd373b77e6e4bf