Age‐associated accumulation of RAB9 disrupts oocyte meiosis.

Authors: Gao, Min^1,2,3 (AUTHOR), Wang, Fang⁴ (AUTHOR), Xu, Tengteng^1,2,5 (AUTHOR), Qiu, Yanling^1,2 (AUTHOR), Cao, Tianqi^1,2 (AUTHOR), Liu, Simiao^1,2 (AUTHOR), Wu, Wenlian^1,2 (AUTHOR), Zhou, Yitong^1,2 (AUTHOR), Liu, Haiying^1,2 (AUTHOR), Liu, Fenghua⁴ (AUTHOR) liushine2006@163.com, Huang, Junjiu^1,2 (AUTHOR) hjunjiu@mail.sysu.edu.cn

Source: Aging Cell. Apr2025, Vol. 24 Issue 4, p1-14. 14p.

Subject Terms: *SPINDLE apparatus, *MEMBRANE potential, *MEIOSIS, *OVUM, *PROTEIN expression

Effects of pentoxifylline on mouse oocytes maturation and quality in vitro.

Authors: Junjiao Wu¹ gwujianbo@163.com, Jianbo Wu¹, Yanyan Xu¹

Source: Iranian Journal of Basic Medical Sciences. Mar2025, Vol. 28 Issue 3, p310-315. 6p.

Subject Terms: *GERMINAL vesicles, *SPINDLE apparatus, *REACTIVE oxygen species, *PENTOXIFYLLINE, *OVUM

The Co-Administration of Paclitaxel with Novel Pyridine and Benzofuran Derivatives that Inhibit Tubulin Polymerisation: A Promising Anticancer Strategy.

Authors: Perużyńska, Magdalena¹ (AUTHOR) magdalena.peruzynska@pum.edu.pl, Birger, Radosław¹ (AUTHOR) marek.drozdzik@pum.edu.pl, Kłos, Patrycja² (AUTHOR) patrycja.klos@pum.edu.pl, Kwiecień, Halina³ (AUTHOR) halina.kwiecien@zut.edu.pl, Struk, Łukasz⁴ (AUTHOR) lukasz.struk@zut.edu.pl, Sośnicki, Jacek G.⁴ (AUTHOR) jacek.sosnicki@zut.edu.pl, Lafanechère, Laurence⁵ (AUTHOR) laurence.lafanechere@univ-grenoble-alpes.fr, Droździk, Marek¹ (AUTHOR)

Source: Pharmaceutics. Feb2025, Vol. 17 Issue 2, p223. 18p.

Subject Terms: *SPINDLE apparatus, *CELL cycle, *ANTINEOPLASTIC agents, *HELA cells, *PYRIDINE derivatives, *TUBULINS

CAMSAP2 is required for bridging fiber assembly to ensure mitotic spindle assembly and chromosome segregation in human epithelial Caco-2 cells.

Authors: Nishizawa, Naoko¹ (AUTHOR), Arai, Riku¹ (AUTHOR), Hiranuma, Koki¹ (AUTHOR), Toya, Mika^1,2,3 (AUTHOR) mikatoya@aoni.waseda.jp, Sato, Masamitsu^1,3,4 (AUTHOR) masasato@waseda.jp

Source: PLoS ONE. 1/9/2025, Vol. 20 Issue 1, p1-28. 28p.

Subject Terms: *SPINDLE apparatus, *HUMAN chromosomes, *MICROTUBULES, *CHROMATIDS, *CARRIER proteins, *CHROMOSOME segregation

Nicotinamide mononucleotide boosts the development of bovine oocyte by enhancing mitochondrial function and reducing chromosome lagging.

Authors: Hashimoto, Shu¹ (AUTHOR) shu@omu.ac.jp, Gamage, Udayanga² (AUTHOR), Inoue, Yuki³ (AUTHOR), Iwata, Hisataka³ (AUTHOR), Morimoto, Yoshiharu² (AUTHOR)

Source: Scientific Reports. 1/2/2025, Vol. 15 Issue 1, p1-11. 11p.

Subject Terms: *NICOTINAMIDE adenine dinucleotide phosphate, *SPINDLE apparatus, *FERTILIZATION in vitro, *ADENOSINE triphosphate, *REACTIVE oxygen species

Unveiling the Movement of RanBP1 During the Cell Cycle and Its Interaction with a Cyclin-Dependent Kinase (CDK) in Plants.

Authors: Thomé, Vanessa^1,2 (AUTHOR) vanessa.thome@usp.br, Ferreira, Pedro B.^1,2 (AUTHOR) pedrobf@alumni.usp.br, Lubini, Greice^1,2 (AUTHOR) greicelubini@gmail.com, Nogueira, Fernanda M.¹ (AUTHOR) edstrini@gmail.com, Strini, Edward J.^1,2 (AUTHOR) vitorpinoti@usp.br, Pinoti, Vitor F.^1,2 (AUTHOR) joelmaioliveira20@gmail.com, Cruz, Joelma O.^1,2 (AUTHOR) jsanmartin@darwin.edu.ar, San Martin, Juca A. B.¹ (AUTHOR) andreacqusp@hotmail.com, Quiapim, Andréa C.¹ (AUTHOR), daSilva, Luis L. P.³ (AUTHOR) lldasilva@fmrp.usp.br, Goldman, Maria Helena S.^1,2 (AUTHOR) mgoldman@ffclrp.usp.br

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 1, p46. 23p.

Subject Terms: *SPINDLE apparatus, *CELL cycle, *CELL proliferation, *TOBACCO, *FLOWER development

Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation.

Authors: Řehulka, Jiří¹ (AUTHOR), Jurášek, Michal² (AUTHOR) michal.jurasek@vscht.cz, Dráber, Pavel³ (AUTHOR), Ivanová, Aleksandra¹ (AUTHOR), Gurská, Soňa¹ (AUTHOR), Ječmeňová, Kateřina¹ (AUTHOR), Mokshyna, Olena^1,4 (AUTHOR), Hajdúch, Marián^1,5 (AUTHOR), Polishchuk, Pavel¹ (AUTHOR), Drašar, Pavel B.² (AUTHOR), Džubák, Petr^1,5 (AUTHOR) petr.dzubak@upol.cz

Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2024, Vol. 39 Issue 1, p1-15. 15p.

Subject Terms: *SPINDLE apparatus, *ESTRADIOL, *ENDOTHELIAL cells, *MOIETIES (Chemistry), *TUBULINS

Spindle integrity is regulated by a phospho-dependent interaction between the Ndc80 and Dam1 kinetochore complexes.

Authors: Nelson, Christian R.¹, Mallett, Darren R.^1,2, Biggins, Sue¹, sbiggins@fredhutch.org

Source: PLoS Genetics; 4/4/2025, Vol. 21 Issue 4, p1-29, 29p

PIWIL1 is recruited to centrosomes during mitosis in colorectal cancer cells and is linked to cell cycle progression.

Authors: Garcia-Silva, Maria Rosa¹ (AUTHOR) rgarcia@pasteur.edu.uy, Montenegro, Sofía¹ (AUTHOR), Dacosta, Sofía¹ (AUTHOR), Tosar, Juan Pablo^1,2 (AUTHOR), Cayota, Alfonso^1,3 (AUTHOR)

Source: Scientific Reports. 10/13/2024, Vol. 14 Issue 1, p1-11. 11p.

Subject Terms: *INDUCED pluripotent stem cells, *SPINDLE apparatus, *STEM cells, *SOMATIC cells, *CANCER cells

Dysfunction of Telomeric Cdc13-Stn1-Ten1 Simultaneously Activates DNA Damage and Spindle Checkpoints.

Authors: Grandin, Nathalie¹ (AUTHOR) nathalie.grandin@uca.fr, Charbonneau, Michel¹ (AUTHOR) michel.charbonneau@uca.fr

Source: Cells (2073-4409). Oct2024, Vol. 13 Issue 19, p1605. 14p.

Subject Terms: *UBIQUITIN ligases, *SPINDLE apparatus, *DNA damage, *CELL cycle, *SEPTINS

Mitotic abnormalities and spindle assembly checkpoint inactivation in a cell model of Shwachman-Diamond syndrome with mutations in the Shwachman-Bodian-Diamond syndrome gene, 258+2T > C.

Authors: Yukihiro Sera¹, Tsuneo Imanaka¹ imanaka@hirokoku-u.ac.jp, Yusuke Iguchi¹, Masafumi Yamaguchi¹

Source: Drug Discoveries & Therapeutics. Oct2024, Vol. 18 Issue 5, p283-289. 7p.

Subject Terms: *SPINDLE apparatus, *CELL cycle, *PROTEIN-tyrosine kinases, *HEMATOLOGIC malignancies, *MYELOID cells

TUBB4B is essential for the expansion of differentiating spermatogonia.

Authors: Sanzhaeva, Urikhan¹ (AUTHOR), Wonsettler, Natalie R.¹ (AUTHOR), Rhodes, Scott B.¹ (AUTHOR), Ramamurthy, Visvanathan^1,2 (AUTHOR) ramamurthyv@hsc.wvu.edu

Source: Scientific Reports. 9/10/2024, Vol. 14 Issue 1, p1-10. 10p.

Subject Terms: *SPINDLE apparatus, *AXONEMES, *GERM cells, *MALE infertility, *MICROTUBULES, *TUBULINS

基于转录组学筛选蓝莓花粉败育相关候选基因.

Alternate Title: Screening of candidate genes related to pollen abortion of blueberry by transcriptomics.

Authors: 杨芩^1,2 yangqin1028518@126.com, 付燕³, 刘雅兰^1,2, 张婷渟^1,2, 彭舒^1,2, 邓洁^1,2

Source: Southwest China Journal of Agricultural Sciences. 2024, Vol. 37 Issue 9, p2018-2030. 13p.

Subject Terms: *POLLEN viability, *SPINDLE apparatus, *MOLECULAR cloning, *CELL differentiation, *GENE ontology, *ANTHER, *BLUEBERRIES

SCM-198 ameliorates the quality of postovulatory and maternally aged oocytes by reducing oxidative stress.

Authors: Ma, Wei^1,2 (AUTHOR), Zhao, Xi² (AUTHOR), Wang, Qingxin¹ (AUTHOR), Wu, Xue^1,2 (AUTHOR), Yang, Tingting^1,2 (AUTHOR), Chen, Yuqi^1,2 (AUTHOR), Zhu, Yizhun³ (AUTHOR) yzzhu@must.edu.mo, Wang, Xia¹ (AUTHOR) tdfywangxia@163.com

Source: Journal of Ovarian Research. 8/31/2024, Vol. 17 Issue 1, p1-15. 15p.

Subject Terms: *EMBRYOLOGY, *SPINDLE apparatus, *CHROMOSOME structure, *REACTIVE oxygen species, *REPRODUCTIVE technology

Upregulation of vesicle-associated membrane protein 7 in breast cancer tissues.

Authors: Huang, Yu¹ (AUTHOR), Wu, Mei² (AUTHOR), Li, Jian-Di² (AUTHOR), Qin, Zhen² (AUTHOR), Huang, Ke-Qiang¹ (AUTHOR), Cui, Jin-Zhu¹ (AUTHOR), Ou, Hai-Ling¹ (AUTHOR) ohl5848712@163.com

Source: Technology & Health Care. 2024, Vol. 32 Issue 4, p2141-2157. 17p.

Subject Terms: *REGULATORY T cells, *SPINDLE apparatus, *GENE expression, *PEARSON correlation (Statistics), *MACROPHAGE activation

Suppressing Anaphase-Promoting Complex/Cyclosome–Cell Division Cycle 20 Activity to Enhance the Effectiveness of Anti-Cancer Drugs That Induce Multipolar Mitotic Spindles.

Authors: Schuyler, Scott C.^1,2 (AUTHOR) schuyler@mail.cgu.edu.tw, Chen, Hsin-Yu¹ (AUTHOR), Chang, Kai-Ping^2,3 (AUTHOR) schuyler@mail.cgu.edu.tw

Source: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 12, p6329. 13p.

Subject Terms: *ANTINEOPLASTIC agents, *SPINDLE apparatus, *DRUG efficacy, *TYPE I interferons, *PACLITAXEL, *INTERFERON receptors

The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans.

Authors: Polisetty, Satya Dev¹, Bhat, Krishna¹, Das, Kuladeep¹, Clark, Ivan², Hardwick, Kevin G.², Sanyal, Kaustuv^1,3, sanyal@jncasr.ac.in

Source: PLoS Genetics; 1/13/2025, Vol. 21 Issue 1, p1-31, 31p

In vitro evaluation of lipidic nanocarriers for mebendazole delivery to improve anticancer activity.

Authors: Tamma, M. Amin¹ (AUTHOR), Nsairat, Hamdi¹ (AUTHOR) h.alnseirat@ammanu.edu.jo, El-Tanani, Mohamed^1,2 (AUTHOR), Madi, Razan¹ (AUTHOR)

Source: Drug Development & Industrial Pharmacy. Nov2024, Vol. 50 Issue 11, p917-926. 10p.

Subject Terms: Spindle apparatus, Antineoplastic agents, Stearic acid, Drug repositioning, Oleic acid, Liposomes, Zeta potential

CFDP1 regulates the stability of pericentric heterochromatin thereby affecting RAN GTPase activity and mitotic spindle formation.

Authors: Gopinathan, Gokul¹ (AUTHOR), Xu, Qian¹ (AUTHOR), Luan, Xianghong¹ (AUTHOR), Diekwisch, Thomas G. H.¹ (AUTHOR) Thomas_Diekwisch@urmc.rochester.edu

Source: PLoS Biology. 4/17/2024, Vol. 22 Issue 4, p1-35. 35p.

Subject Terms: *SPINDLE apparatus, *HETEROCHROMATIN, *HISTONES, *NATURAL satellites, *GUANOSINE triphosphatase, *MICROTUBULES, *PROTEIN stability

Mitotic Functions and Characters of KIF11 in Cancers.

Authors: Gao, Wanting¹ (AUTHOR), Lu, Junjie¹ (AUTHOR), Yang, Zitao¹ (AUTHOR) 20wtgao@stu.edu.cn, Li, Enmin¹ (AUTHOR), Cao, Yufei¹ (AUTHOR) 17yfcao@alumni.stu.edu.cn, Xie, Lei¹ (AUTHOR) 17yfcao@alumni.stu.edu.cn

Source: Biomolecules (2218-273X). Apr2024, Vol. 14 Issue 4, p386. 22p.

Subject Terms: *SPINDLE apparatus, *CANCER invasiveness, *MITOSIS, *KINESIN, *CELL separation