The magnetic beads-based sandwich-shaped immune complexes for rapid and sensitive amperometric detection of SOX2 protein.

Authors: ÖZÇELİKAY AKYILDIZ, Göksu¹, ÜNAL, Mehmet Altay², GÜLDEN, Seçil³, ÖZKAN, Sibel A.¹ ozkan@pharmacy.ankara.edu.tr

Source: Turkish Journal of Chemistry. 2025, Vol. 49 Issue 1, p79-88. 10p.

Subject Terms: *TRANSCRIPTION factors, *SOX2 protein, *IMMUNE complexes, *LYMPHATIC metastasis, *CARBON electrodes

ZFP64 drives glycolysis-mediated stem cell-like properties and tumorigenesis in breast cancer.

Authors: Sun, Jiayi¹ (AUTHOR), Liu, Jinquan² (AUTHOR), Hou, Yudong³ (AUTHOR), Bao, Jianheng³ (AUTHOR), Wang, Teng³ (AUTHOR), Liu, Longbi³ (AUTHOR), Zhang, Yidan³ (AUTHOR), Zhong, Rui³ (AUTHOR), Sun, Zhenxuan³ (AUTHOR), Ye, Yan⁴ (AUTHOR), Liu, Jintao⁴ (AUTHOR) liujintao77@aliyun.com

Source: Biology Direct. 9/18/2024, Vol. 19 Issue 1, p1-14. 14p.

Subject Terms: *TRANSCRIPTION factors, *SOX2 protein, *PROGRESSION-free survival, *PROGESTERONE receptors, *OVERALL survival, *ZINC-finger proteins

A novel SOX2 frameshift pathogenic variant located in the transactivation domain in a male infant with hypogonadotropic hypogonadism.

Authors: Ayano Kimura-Yoshida¹, Takeshi Sato¹, Yosuke Ichihashi¹, Masanori Wasa², Satoshi Narumi¹, Tomohiro Ishii¹, Tomonobu Hasegawa¹, thaseg@keio.jp

Source: Clinical Pediatric Endocrinology; 2024, Vol. 33 Issue 4, p244-248, 5p

AKT1 induces Nanog promoter in a SUMOylation-dependent manner in different pluripotent contexts.

Authors: Francia, Marcos Gabriel¹ (AUTHOR), Verneri, Paula¹ (AUTHOR), Oses, Camila¹ (AUTHOR), Vazquez Echegaray, Camila^1,2 (AUTHOR), Garcia, Mora Reneé¹ (AUTHOR), Toro, Ayelen¹ (AUTHOR), Levi, Valeria¹ (AUTHOR), Guberman, Alejandra Sonia^1,3,4 (AUTHOR) algub@qb.fcen.uba.ar

Source: BMC Research Notes. 11/3/2023, Vol. 16 Issue 1, p1-9. 9p.

Subject Terms: *EMBRYONIC stem cells, *SOX2 protein, *PLURIPOTENT stem cells, *POST-translational modification, *TRANSCRIPTION factors

Detection of Recombinant Proteins SOX2 and OCT4 Interacting in HEK293T Cells Using Real-Time Quantitative PCR.

Authors: Kanayev, Darkhan¹ (AUTHOR), Abilmazhenova, Diana¹ (AUTHOR), Akhmetollayev, Ilyas¹ (AUTHOR), Sekenova, Aliya¹ (AUTHOR), Ogay, Vyacheslav¹ (AUTHOR), Kulyyassov, Arman¹ (AUTHOR) kulyyasov@biocenter.kz

Source: Life (2075-1729). Jan2023, Vol. 13 Issue 1, p107. 10p.

Subject Terms: *RECOMBINANT proteins, *SOX2 protein, *COLLISION broadening, *TRANSCRIPTION factors, *REVERSE transcriptase polymerase chain reaction

Production and characterization of a new specific monoclonal antibody against A‐isoform of SALL4: A novel emerging testicular cancer marker.

Authors: Lakpour, Niknam^1,2 (AUTHOR), Ghods, Roya^1,3 (AUTHOR) ghods.ro@iums.ac.ir, Sadeghi, Mohammad Reza² (AUTHOR) sadeghi@avicenna.ac.ir, Ranjbar, Mohammad Mehdi⁴ (AUTHOR), Abolhasani, Maryam⁵ (AUTHOR), Kiani, Jafar^1,3 (AUTHOR), Saliminejad, Kioomars² (AUTHOR), Balay‐Goli, Leila² (AUTHOR), Bayat, Ali Ahmad⁶ (AUTHOR), Souri, Fahimeh⁶ (AUTHOR), Madjd, Zahra^1,3,5 (AUTHOR) majdjabari.z@iums.ac.ir

Source: Andrologia. Dec2022, Vol. 54 Issue 11, p1-10. 10p.

Subject Terms: *SOX2 protein, *TESTICULAR cancer, *MONOCLONAL antibodies, *TUMOR markers, *RECOMBINANT proteins, *PEPTIDES

Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells.

Authors: Shimizu, Masahiro^1,2 (AUTHOR), Shibuya, Hiroshi² (AUTHOR), Tanaka, Nobuyuki¹ (AUTHOR) nobuta@nms.ac.jp

Source: Scientific Reports. 2/21/2022, Vol. 12 Issue 1, p1-13. 13p.

Subject Terms: *CANCER stem cells, *SOX2 protein, *PROTEIN expression, *SOMATIC cells, *CELLULAR signal transduction

Targeting AKT as a promising strategy for SOX2-positive, chemoresistant osteosarcoma.

Authors: Liu, Yujie, Kang, Li, Luo, Jing, Yang, Minglei, Wang, Da, Ye, Juelan, Yang, Xinghai, Wan, Wei, Wong, Jiemin, Xiao, Jianru

Source: Bone Research; 2/24/2025, Vol. 13 Issue 1, p1-13, 13p

Subject Terms: SOX2 protein, MEDICAL sciences, TUMOR growth, PROTEIN stability, GENETIC transcription

Influences of CircRHOT1 on proliferation, apoptosis and immune escape of breast cancer cells by regulating miR-187-3p/SOX4 axis.

Authors: SUN Pei¹, JIANG Zhenwei¹ sfran16@163.com, LIU Qian²

Source: Chinese Journal of Immunology. Mar2024, Vol. 40 Issue 3, p577-585. 9p.

Subject Terms: *CANCER cells, *SOX2 protein, *BREAST cancer, *GENE expression, *CIRCULAR RNA, *MICRORNA

LncRNA linc01194 promotes the progress of endometrial carcinoma by up-regulating SOX2 through binding to IGF2BP1.

Authors: Zhenghao Huang¹, Fan Shen¹, Jingwen Chen¹, Bumin Xie¹, Xi Chen¹, Yang Zhao¹ yida.zhaoyang@163.com, Shuo Chen¹

Source: Journal of Gynecologic Oncology. Mar2024, Vol. 35 Issue 2, p1-12. 12p.

Subject Terms: *SOX2 protein, *INSULIN-like growth factor-binding proteins, *ENDOMETRIAL cancer, *GENE expression, *LINCRNA, *INHIBITION of cellular proliferation

Nectin-4 and p95-ErbB2 cooperatively regulate Hippo signaling-dependent SOX2 gene expression, enhancing anchorage-independent T47D cell proliferation.

Authors: Kedashiro, Shin¹, Kameyama, Takeshi¹, Mizutani, Kiyohito¹ mizutani@med.kobe-u.ac.jp, Takai, Yoshimi¹ ytakai@med.kobe-u.ac.jp

Source: Scientific Reports. 4/1/2021, Vol. 11 Issue 1, p1-17. 17p.

Subject Terms: *NECTINS, *SOX2 protein, *GENE expression, *CELL proliferation, *TRASTUZUMAB

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing.

Authors: Kim, Jessica¹, Muraoka, Masafumi², Okada, Hajime², Toyoda, Atsushi³, Ajima, Rieko^2,4, rajima@nig.ac.jp, Saga, Yumiko^1,2,4, rajima@nig.ac.jp

Source: PLoS Genetics; 10/05/2022, Vol. 18 Issue 10, p1-33, 33p

Leptin improves the in vitro development of preimplantation rabbit embryos under oxidative stress of cryopreservation.

Authors: Alshaheen, Tarek A.¹ (AUTHOR), Awaad, Mohamed H. H.² (AUTHOR), Mehaisen, Gamal M. K.³ (AUTHOR) gamoka@cu.edu.eg

Source: PLoS ONE. 2/2/2021, Vol. 16 Issue 2, p1-16. 16p.

Subject Terms: *SOX2 protein, *LEPTIN, *HEAT shock proteins

Bufalin attenuates triple-negative breast cancer cell stemness by inhibiting the expression of SOX2/OCT4.

Authors: FEI CHEN¹, LI ZHU², JUNYAN HU¹, SHUJUN JIANG¹, HUI LIU¹, JIE ZHENG¹, JIANDONG WANG¹, FENG WANG¹, ZHE LI¹ lizhezsh@shutcm.edu.cn

Source: Oncology Letters. Nov2020, Vol. 20 Issue 5, p1-9. 9p.

Subject Terms: *TRIPLE-negative breast cancer, *SOX2 protein, *CANCER cells, *CANCER stem cells, *CELL cycle, *STEM cells, *CHINESE medicine

Immunohistochemical analysis of SOX2 expression in small-cell neuroendocrine carcinoma of the endometrium.

Authors: Ebisu, Yusuke¹ (AUTHOR), Ishida, Mitsuaki¹ (AUTHOR) ishidamt@hirakata.kmu.ac.jp, Mizokami, Tomomi² (AUTHOR), Kita, Masato² (AUTHOR), Okada, Hidetaka² (AUTHOR), Tsuta, Koji¹ (AUTHOR)

Source: Molecular & Clinical Oncology. Aug2020, Vol. 13 Issue 2, p115-118. 4p.

Subject Terms: *SOX2 protein, *EMBRYONIC stem cells, *ENTEROCOLITIS, *P16 gene, *CARCINOMA, *PATHOLOGY, *HEMATEMESIS, *ENDOMETRIUM

IFN β signaling inhibits osteogenesis in human SLE bone marrow.

Authors: Gao, Lin¹ (AUTHOR) Lin_Gao@urmc.rochester.edu, Liesveld, Jane¹ (AUTHOR), Anolik, Jennifer¹ (AUTHOR), Mcdavid, Andrew¹ (AUTHOR), Looney, Richard John¹ (AUTHOR)

Source: Lupus. Aug2020, Vol. 29 Issue 9, p1040-1049. 10p. 6 Graphs.

Subject Terms: *SOX2 protein, *BONE marrow, *MESENCHYMAL stem cell differentiation, *LUPUS nephritis, *RUNX proteins, *MULTIPOTENT stem cells, *MESENCHYMAL stem cells, *SYSTEMIC lupus erythematosus

Advances in understanding the regulation of pluripotency fate transition in embryonic stem cells.

Authors: Jia, Yong kang, Yu, Yang, Guan, Li

Source: Frontiers in Cell & Developmental Biology; 2024, p1-11, 11p

Subject Terms: EMBRYONIC stem cells, MAMMALIAN embryos, FETAL tissues, CELL populations, RESEARCH personnel, SOX2 protein

Feedback loop LINC00511–YTHDF2–SOX2 regulatory network drives cholangiocarcinoma progression and stemness.

Authors: Guan, Canghai, Zou, Xinlei, Gao, Xin, Liu, Sidi, Gao, Jianjun, Shi, Wujiang, Dong, Qingfu, Jiang, Xingming, Zhong, Xiangyu

Source: MedComm; Nov2024, Vol. 5 Issue 11, p1-19, 19p

Subject Terms: LINCRNA, TRANSCRIPTION factors, SOX2 protein, PI3K/AKT pathway, PROTEIN expression

Advances in understanding the regulation of pluripotency fate transition in embryonic stem cells.

Authors: Yong kang Jia, Yang Yu, Li Guan

Source: Frontiers in Cell & Developmental Biology; 2024, p01-11, 11p

Subject Terms: EMBRYONIC stem cells, MAMMALIAN embryos, FETAL tissues, CELL populations, RESEARCH personnel, SOX2 protein

Synthetic and immunological studies on the OCT4 immunodominant motif antigen-based anti-cancer vaccine.

Authors: Tingting Chen¹, Kan Liu¹, Jiangyao Xu¹, Tianying Zhan¹, Maixian Liu¹, Li Li¹, Zhiwen Yang¹, Shuping Yuan¹, Wenyi Zou¹, Guimiao Lin¹, Carson, Dennis A.^1,2, Wu, Christina C. N.^1,2, Xiaomei Wang¹ xmwang@szu.edu.cn

Source: Cancer Biology & Medicine. Feb2020, Vol. 17 Issue 1, p132-141. 10p.

Subject Terms: *SOX2 protein, *BACTERIAL vaccines, *CYTOTOXIC T cells, *EMBRYONIC stem cells, *CANCER vaccines, *CARRIER proteins, *VACCINES