Dynamics of SERPINA3 in response to anthracycline treatment and cardiovascular dysfunction

Authors: Hanne M. Boen, Lobke L. Pype, Konstantinos Papadimitriou, Sevilay Altintas, Laure-Anne Teuwen, Sébastien Anguille, Kirsten Saevels, Anke Verlinden, Leen Delrue, Ward A. Heggermont, Matthias Bosman, Pieter-Jan Guns, Hein Heidbuchel, Caroline M. Van De Heyning, Emeline M. Van Craenenbroeck, Constantijn Franssen

Source: Cardio-Oncology, Vol 11, Iss 1, Pp 1-13 (2025)

Subject Terms: Cancer therapy-related cardiac dysfunction (CTRCD), SERPINA3, Cardiotoxicity, Biomarker, Anthracycline, Breast cancer, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2057-3804

Access URL: https://doaj.org/article/7df43c30a7364c1a9910cb12320980e9

Dexrazoxane prevents vascular toxicity in doxorubicin-treated mice

Authors: Dustin N. Krüger, Matthias Bosman, Emeline M. Van Craenenbroeck, Guido R. Y. De Meyer, Constantijn Franssen, Pieter-Jan Guns

Source: Cardio-Oncology, Vol 10, Iss 1, Pp 1-11 (2024)

Subject Terms: Doxorubicin, Dexrazoxane, Vascular toxicity, Endothelial cell dysfunction, SERPINA3, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2057-3804

Access URL: https://doaj.org/article/56a98f05017b45b4b30d87d48e86a2eb

Sex-related differences in the prognostic utility of inflammatory and thrombotic cardiovascular risk markers in patients with chest pain of suspected coronary origin

Authors: Dennis Winston T. Nilsen, Reidun Aarsetoey, Volker Poenitz, Thor Ueland, Pål Aukrust, Annika Elisabet Michelsen, Trygve Brugger-Andersen, Harry Staines, Heidi Grundt

Source: International Journal of Cardiology: Heart & Vasculature, Vol 56, Iss , Pp 101600- (2025)

Subject Terms: Gender/sex, Biomarkers, SERPINA3, D-dimer, acute coronary syndrome (ACS), cardiovascular disease (CVD) events/mortality, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S235290672500003X; https://doaj.org/toc/2352-9067

Access URL: https://doaj.org/article/76591c92ad4f40b1b232f0332f7f2b41

Decoding early-onset of colorectal cancer: Insights into SERPINA3 expression patterns

Authors: Anjana Soman, Tapas Pradhan, R. Krishna, Evangeline Surya Hermon, Thara Somanathan, Jinto Edakkalathoor George, Gejoe George, Ramesh Pothuraju, S. Asha Nair

Source: Heliyon, Vol 10, Iss 22, Pp e40119- (2024)

Subject Terms: Early-onset of colorectal cancer, SERPINA3, Inflammation, Stroma, Epithelial cell, Colorectal cancer, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024161506; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/2e88eae44ea841d8ad485756376845af

Characterization of systolic and diastolic function, alongside proteomic profiling, in doxorubicin-induced cardiovascular toxicity in mice

Authors: Dustin N. Krüger, Matthias Bosman, Charles X.L. Van Assche, Callan D. Wesley, Berta Cillero-Pastor, Leen Delrue, Ward Heggermont, Jozef Bartunek, Guido R. Y. De Meyer, Emeline M. Van Craenenbroeck, Pieter-Jan Guns, Constantijn Franssen

Source: Cardio-Oncology, Vol 10, Iss 1, Pp 1-17 (2024)

Subject Terms: Doxorubicin, Cardiovascular toxicity, Serpina3, Diastolic dysfunction, Heart failure, Biomarker, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2057-3804

Access URL: https://doaj.org/article/be96370b15b24456a6a68e11cd636233

Unveiling the role of miR-137-3p/miR-296-5p/SERPINA3 signaling in colorectal cancer progression: integrative analysis of gene expression profiles and in vitro studies

Authors: Huimin Liu, Xingxing Wu, Dandan Wang, Quanxi Li, Xin Zhang, Liang Xu

Source: BMC Medical Genomics, Vol 16, Iss 1, Pp 1-16 (2023)

Subject Terms: Colorectal cancer, Metastasis, Bioinformatics analysis, DEGs, SERPINA3, miR-137-3p, miR-296-5p, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/de229f21ed254e8fa66007a82bd27103

Osteoblast‐derived extracellular vesicles exert osteoblastic and tumor‐suppressive functions via SERPINA3 and LCN2 in prostate cancer

Authors: Kagenori Ito, Tomofumi Yamamoto, Yusuke Hayashi, Shun Sato, Jun Nakayama, Fumihiko Urabe, Takeo Shimasaki, Eijiro Nakamura, Yoshiyuki Matui, Hiroyuki Fujimoto, Takahiro Kimura, Shin Egawa, Takahiro Ochiya, Yusuke Yamamoto

Source: Molecular Oncology, Vol 17, Iss 10, Pp 2147-2167 (2023)

Subject Terms: extracellular vesicles, LCN2, osteoblastic bone metastasis, prostate cancer, SERPINA3, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/552f86d13f2e40149574c3164a08091a

Potential diagnostic markers shared between non-alcoholic fatty liver disease and atherosclerosis determined by machine learning and bioinformatic analysis

Authors: Lihong Wang, Wenhui He, Xilin Wang, Jianrong Wang, Xiaojuan Wei, Dongzhi Wu, Yundan Wu

Source: Frontiers in Medicine, Vol 11 (2024)

Subject Terms: non-alcoholic fatty liver disease, atherosclerosis, RPS6KA1, SERPINA3, bioinformatics, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2024.1322102/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/1ddc3e5b01c44abaa9c90c6d9010025a

Prediction Value of Initial Serum Levels of SERPINA3 in Intracranial Pressure and Long-Term Neurological Outcomes in Traumatic Brain Injury

Authors: Haoyuan Tan, Jiamian Wang, Fengshi Li, Yidong Peng, Jin Lan, Yuanda Zhang, Dongxu Zhao, Yinghui Bao

Source: Diagnostics, Vol 14, Iss 12, p 1245 (2024)

Subject Terms: SERPINA3, traumatic brain injury, rehabilitation, intensive care unit, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/14/12/1245; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/18c108e22ddd483baa66ec7b171d4727

HOXA-AS2 enhances GBM cell malignancy by suppressing miR-2116-3p thereby upregulating SERPINA3

Authors: Jianrui Sun, Lin Wang

Source: BMC Cancer, Vol 22, Iss 1, Pp 1-14 (2022)

Subject Terms: HOXA-AS2, miR-2116-3p, SERPINA3, Glioblastoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/38ccabdfc6154b73a170adbd50daa9ab

SERPIN-A3 is associated with persistent albuminuria in adolescents with secondary podocytopathy, in a region with high prevalence of chronic kidney disease of unknown origin

Authors: Leslie P. Zúñiga-Macías, Ricardo E. Ramírez-Orozco, Francisco J. Avelar-González, Rosalba Pérez-Villalva, Norma A. Bobadilla, José M. Arreola-Guerra

Source: Revista de Investigación Clínica, Vol 75, Iss 2 (2023)

Subject Terms: Persistent albuminuria. SerpinA3. Chronic kidney disease of unknown origin. Glomerular hyperfiltration. Aguascalientes., Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://www.clinicalandtranslationalinvestigation.com/frame_esp.php?id=456; https://doaj.org/toc/0034-8376; https://doaj.org/toc/2564-8896

Access URL: https://doaj.org/article/1b6323d14ebf4cfd94a72b8bff271b86

Multiple-model machine learning identifies potential functional genes in dilated cardiomyopathy

Authors: Lin Zhang, Yexiang Lin, Kaiyue Wang, Lifeng Han, Xue Zhang, Xiumei Gao, Zheng Li, Houliang Zhang, Jiashun Zhou, Heshui Yu, Xuebin Fu

Source: Frontiers in Cardiovascular Medicine, Vol 9 (2023)

Subject Terms: diagnosis value, dilated cardiomyopathy, machine learning, SERPINA3, FRZB, FCN3, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2022.1044443/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/f7e9e0bb7ead4bebadb20bedd3e8e3b5

Highly expressed of SERPINA3 indicated poor prognosis and involved in immune suppression in glioma

Authors: Qing Yuan, Song‐Quan Wang, Guang‐Tao Zhang, Jie He, Zhi‐Dan Liu, Ming‐Rong Wang, Hong‐Qing Cai, Jing‐Hai Wan

Source: Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1618-1630 (2021)

Subject Terms: glioma, immune response, prognosis, SERPINA3, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2050-4527

Access URL: https://doaj.org/article/fe6d5b9851a54c37a27416b077301937

CircSERPINA3 regulates SERPINA3-mediated apoptosis, autophagy and aerobic glycolysis of prostate cancer cells by competitively binding to MiR-653-5p and recruiting BUD13

Authors: Zengshu Xing, Sailian Li, Zhenxiang Liu, Chong Zhang, Zhiming Bai

Source: Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)

Subject Terms: circSERPINA3, SERPINA3, miR-653-5p, BUD13, Prostate cancer, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/87d008945f604d588c0d9bff66ce9fd1

Immune-related SERPINA3 as a biomarker involved in diabetic nephropathy renal tubular injury

Authors: Zuyan Fan, Yan Gao, Nan Jiang, Fengxia Zhang, Shuangxin Liu, Quhuan Li

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: diabetic nephropathy, renal tubules, RNA-Seq, bioinformatic, SERPINA3, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.979995/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/46a5736bea6b442d9bf5d06da790f9cd

Screening and identification of tissue-infiltrating immune cells and genes for patients with emphysema phenotype of COPD

Authors: Di Wang, Bingnan Chen, Shuang Bai, Li Zhao

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: emphysema phenotype, tissue-infiltrating immune cells, SERPINA3, emphysema risk prediction model, bioinformatics, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.967357/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/411748b235504b7ea34947fb7d5a4323

Corrigendum: Exploration of the Role of Serine Proteinase Inhibitor A3 in Alcohol Dependence Using Gene Expression Omnibus Database

Authors: Bo Zhang, Gang Wang, Cheng Bing Huang, Jian Nan Zhu, Yong Xue, Jian Hu

Source: Frontiers in Psychiatry, Vol 13 (2022)

Subject Terms: alcohol dependence, bioinformatics analysis, differently expressed genes, SERPINA3, relapse biomarkers, Psychiatry, RC435-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpsyt.2022.857211/full; https://doaj.org/toc/1664-0640

Access URL: https://doaj.org/article/8711d391bebf4c258e8ec5ef8568ad90

Exploration of the Role of Serine Proteinase Inhibitor A3 in Alcohol Dependence Using Gene Expression Omnibus Database

Authors: Bo Zhang, Gang Wang, Cheng Bing Huang, Jian Nan Zhu, Yong Xue, Jian Hu

Source: Frontiers in Psychiatry, Vol 12 (2022)

Subject Terms: alcohol dependence, bioinformatics analysis, differently expressed genes, SERPINA3, relapse biomarkers, Psychiatry, RC435-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpsyt.2021.779143/full; https://doaj.org/toc/1664-0640

Access URL: https://doaj.org/article/5b7fbaca5b5c465fb2d5eec306c9b74d

SERPINA3: Stimulator or Inhibitor of Pathological Changes

Authors: Mateusz de Mezer, Jan Rogaliński, Stanisław Przewoźny, Michał Chojnicki, Leszek Niepolski, Magdalena Sobieska, Agnieszka Przystańska

Source: Biomedicines, Vol 11, Iss 1, p 156 (2023)

Subject Terms: SERPINA3, α-1-antichymotrypsin, anti-inflammatory, antiapoptotic, DNA binding, PI3K/AKT, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/11/1/156; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/c87828ba00254723899993e116641441

The Association and Pathogenesis of SERPINA3 in Coronary Artery Disease

Authors: Bo Li, Zhijun Lei, You Wu, Bingyu Li, Ming Zhai, Yuan Zhong, Peinan Ju, Wenxin Kou, Yefei Shi, Xianling Zhang, Wenhui Peng

Source: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Subject Terms: SERPINA3, CAD, atherosclerosis, RASMCs, HUVECs, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2021.756889/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/ce7a521720c6474e81debc25b6f0cde4