Deferasirox Targeting Ferroptosis Synergistically Ameliorates Myocardial Ischemia Reperfusion Injury in Conjunction With Cyclosporine A

Authors: Kosei Ishimaru, Masataka Ikeda, Hiroko Deguchi Miyamoto, Shun Furusawa, Ko Abe, Masatsugu Watanabe, Takuya Kanamura, Satoshi Fujita, Ryohei Nishimura, Takayuki Toyohara, Shouji Matsushima, Tomoko Koumura, Ken‐ichi Yamada, Hirotaka Imai, Hiroyuki Tsutsui, Tomomi Ide

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 1 (2024)

Subject Terms: cyclosporin A, deferasirox, ferroptosis, ischemia reperfusion injury, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/dbaf2db9f0a143d98668818ad9250cb5

Bladder Reconstruction in Cats Using In-Body Tissue Architecture (iBTA)-Induced Biosheet

Authors: Naoki Fujita, Fumi Sugiyama, Masaya Tsuboi, Hazel Kay Nakamura, Ryohei Nishimura, Yasuhide Nakayama, Atsushi Fujita

Source: Bioengineering, Vol 11, Iss 6, p 615 (2024)

Subject Terms: in body tissue architecture (iBTA), cat, urinary tract reconstruction, Technology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2306-5354/11/6/615; https://doaj.org/toc/2306-5354

Access URL: https://doaj.org/article/5e90954405b9469baf0065c8a36f4c2a

The impact of damage-associated molecules released from canine tumor cells on gene expression in macrophages

Authors: Shotaro Eto, Hideyuki Yanai, Sho Hangai, Daiki Kato, Ryohei Nishimura, Takayuki Nakagawa

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/22d60bea34a74a2f9e372f6b97c7a09b

Early escitalopram administration as a preemptive treatment strategy against spasticity after contusive spinal cord injury in rats

Authors: Youngjae Ryu, Toru Ogata, Motoshi Nagao, Yasuhiro Sawada, Ryohei Nishimura, Naoki Fujita

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/f69cb93e96a341c7a8c62d60adc9ad1c

Anti-CCR4 treatment depletes regulatory T cells and leads to clinical activity in a canine model of advanced prostate cancer

Authors: Tomoki Motegi, Takayuki Nakagawa, Shingo Maeda, Aki Iio, Kenjiro Kaji, Yuko Goto-Koshino, Shotaro Eto, Namiko Ikeda, Ryohei Nishimura, Tomohiro Yonezawa, Yasuyuki Momoi

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/2/e003731.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/a31d4e8d108b4347a9e966ac1b63ac80

GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway

Authors: Akihito Ishikita, Shouji Matsushima, Soichiro Ikeda, Kosuke Okabe, Ryohei Nishimura, Tomonori Tadokoro, Nobuyuki Enzan, Taishi Yamamoto, Masashi Sada, Yoshitomo Tsutsui, Ryo Miyake, Masataka Ikeda, Tomomi Ide, Shintaro Kinugawa, Hiroyuki Tsutsui

Source: iScience, Vol 24, Iss 12, Pp 103517- (2021)

Subject Terms: Classification Description: Cellular physiology, Molecular physiology, Cell biology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004221014887; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/1a1423f963444dff93d60619b505cc28

Extracellular Vesicles Derived From Canine Mesenchymal Stromal Cells in Serum Free Culture Medium Have Anti-inflammatory Effect on Microglial Cells

Authors: Yukina Kuwahara, Karin Yoshizaki, Hidetaka Nishida, Hiroaki Kamishina, Sadatoshi Maeda, Katsura Takano, Naoki Fujita, Ryohei Nishimura, Jun-ichiro Jo, Yasuhiko Tabata, Hideo Akiyoshi

Source: Frontiers in Veterinary Science, Vol 8 (2021)

Subject Terms: exosome, extracellular vesicles, canine, mesenchymal stromal cells, anti-inflammatory, serum free culture, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fvets.2021.633426/full; https://doaj.org/toc/2297-1769

Access URL: https://doaj.org/article/31b57afb2ec24aea87f60f7b4e802389

GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab

Authors: Daiki Kato, Tomonori Yaguchi, Takashi Iwata, Yuki Katoh, Kenji Morii, Kinya Tsubota, Yoshiaki Takise, Masaki Tamiya, Haruhiko Kamada, Hiroki Akiba, Kouhei Tsumoto, Satoshi Serada, Tetsuji Naka, Ryohei Nishimura, Takayuki Nakagawa, Yutaka Kawakami

Source: eLife, Vol 9 (2020)

Subject Terms: adverse effects, anti-PD-1 Ab, combination immunotherapy, CAR-T cells, solid tumor, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/49392; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/d030ebf95bdf404e87e0c8329118623a

Immunohistochemical evaluation of HER2 expression in canine thyroid carcinoma

Authors: Sho Yoshimoto, Daiki Kato, Satoshi Kamoto, Kie Yamamoto, Masaya Tsuboi, Masahiro Shinada, Namiko Ikeda, Yuiko Tanaka, Ryohei Yoshitake, Shotaro Eto, Kohei Saeki, James Chambers, Ryohei Kinoshita, Kazuyuki Uchida, Ryohei Nishimura, Takayuki Nakagawa

Source: Heliyon, Vol 5, Iss 7, Pp e02004- (2019)

Subject Terms: Cancer research, Veterinary medicine, Pathology, Oncology, Thyroid cancer, Canis familiaris, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844019356506; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/c826c08557774a318c223e2cf03be560

Phase I/II Clinical Trial of the Anti-Podoplanin Monoclonal Antibody Therapy in Dogs with Malignant Melanoma

Authors: Satoshi Kamoto, Masahiro Shinada, Daiki Kato, Sho Yoshimoto, Namiko Ikeda, Masaya Tsuboi, Ryohei Yoshitake, Shotaro Eto, Yuko Hashimoto, Yosuke Takahashi, James Chambers, Kazuyuki Uchida, Mika K. Kaneko, Naoki Fujita, Ryohei Nishimura, Yukinari Kato, Takayuki Nakagawa

Source: Cells, Vol 9, Iss 11, p 2529 (2020)

Subject Terms: podoplanin, dog, antibody therapy, tumor, melanoma, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/11/2529; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/3eb3786967f4411aaccfb5688edd0290

PDPN Is Expressed in Various Types of Canine Tumors and Its Silencing Induces Apoptosis and Cell Cycle Arrest in Canine Malignant Melanoma

Authors: Masahiro Shinada, Daiki Kato, Satoshi Kamoto, Sho Yoshimoto, Masaya Tsuboi, Ryohei Yoshitake, Shotaro Eto, Namiko Ikeda, Kohei Saeki, Yuko Hashimoto, Yosuke Takahashi, James Chambers, Kazuyuki Uchida, Mika K. Kaneko, Naoki Fujita, Ryohei Nishimura, Yukinari Kato, Takayuki Nakagawa

Source: Cells, Vol 9, Iss 5, p 1136 (2020)

Subject Terms: podoplanin, cancer, Ki67, melanoma, squamous cell carcinoma, apoptosis, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/5/1136; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/3b34a7c8387b45768d7edbc917ff1d65

Anti-tumor effects of the histone deacetylase inhibitor vorinostat on canine urothelial carcinoma cells.

Authors: Shotaro Eto, Kohei Saeki, Ryohei Yoshitake, Sho Yoshimoto, Masahiro Shinada, Namiko Ikeda, Satoshi Kamoto, Yuiko Tanaka, Daiki Kato, Shingo Maeda, Masaya Tsuboi, James Chambers, Kazuyuki Uchida, Ryohei Nishimura, Takayuki Nakagawa

Source: PLoS ONE, Vol 14, Iss 6, p e0218382 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/74e82af3ac9642e29d29432edaf683fa

The swimming test is effective for evaluating spasticity after contusive spinal cord injury.

Authors: Youngjae Ryu, Toru Ogata, Motoshi Nagao, Taku Kitamura, Kazuhito Morioka, Yoshinori Ichihara, Toru Doi, Yasuhiro Sawada, Masami Akai, Ryohei Nishimura, Naoki Fujita

Source: PLoS ONE, Vol 12, Iss 2, p e0171937 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5300247?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/2c6cc97d371e4b9fbbe3e70a78009143

A Newly Developed Immunoisolated Bioartificial Pancreas with Cell Sheet Engineering

Authors: Jeong Ik Lee, Ryohei Nishimura, Hideaki Sakai, Nobuo Sasaki, Takashi Kenmochi M.D., Ph.D.

Source: Cell Transplantation, Vol 17 (2008)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/0963-6897; https://doaj.org/toc/1555-3892

Access URL: https://doaj.org/article/d35e92d2947445af9cf31b4ed7d132cd

Anti-tumor effect of proteasome inhibitor on canine urothelial carcinoma.

Authors: Yuka KODERA, Takaaki IGUCHI, Daiki KATO, Namiko IKEDA, Masahiro SHINADA, Susumu AOKI, Kyoka SOGA, Toshio LI, Ryosuke OHATA, Shoma KOSEKI, Hayato SHIBAHARA, Yosuke TAKAHASHI, Yuko HASHIMOTO, Ryohei NISHIMURA, Takayuki NAKAGAWA

Source: Journal of Veterinary Medical Science; 2024, Vol. 86 Issue 9, p961-965, 5p

Subject Terms: PROTEASOME inhibitors, TRANSITIONAL cell carcinoma, PROTEOLYSIS, CELL growth, CELL lines, BORTEZOMIB

Evaluation of semitendinosus muscle transposition for treatment of perineal hernias in 33 small-breed dogs.

Authors: Yuko Hashimoto, Takayuki Nakagawa, Ryohei Nishimura

Source: Canadian Journal of Veterinary Research / Revue Canadienne de Recherche Vétérinaire; Oct2023, Vol. 87 Issue 4, p282-289, 8p

Subject Terms: HERNIA surgery, HERNIA, SURGICAL complications, OPERATIVE surgery, TELEPHONE interviewing, DOGS

Company/Entity: TOKYO Daigaku

Podoplanin promotes cell proliferation, survival, and migration of canine non-tonsillar squamous cell carcinoma.

Authors: Masahiro SHINADA, Daiki KATO, Masaya TSUBOI, Namiko IKEDA, Susumu AOKI, Takaaki IGUCHI, Toshio LI, Yuka KODERA, Ryosuke OTA, Shoma KOSEKI, Hayato SHIBAHARA, Yosuke TAKAHASHI, Yuko HASHIMOTO, CHAMBERS, James K., Kazuyuki UCHIDA, Shunsuke NOGUCHI, Yukinari KATO, Ryohei NISHIMURA, Takayuki NAKAGAWA

Source: Journal of Veterinary Medical Science; 2023, Vol. 85 Issue 10, p1068-1073, 6p

Subject Terms: SQUAMOUS cell carcinoma, CELL proliferation, CELL cycle, PROGNOSIS, CANCER invasiveness

Detection of domestic cat hepadnavirus by next-generation sequencing and epidemiological survey in Japan.

Authors: Haruka SAKAMOTO, Genta ITO, Yuko GOTO-KOSHINO, Megumi SAKAMOTO, Ryohei NISHIMURA, Yasuyuki MOMOI

Source: Journal of Veterinary Medical Science; 2023, Issue 6, p642-646, 5p

Subject Terms: CATS, NUCLEOTIDE sequencing, LIVER enzymes, VETERINARY hospitals, DOMESTIC fiction, HEPATITIS viruses

Geographic Terms: AUSTRALIA, JAPAN

Canine bone marrow peri-adipocyte cells could therapeutically benefit acute spinal cord injury through migration and secretion of hepatocyte growth factor to inflammatory milieu.

Authors: Junyan CHEN, Naoki FUJITA, Tae TAKEDA, Wataru HANYU, Hirohide TAKATANI, Takayuki NAKAGAWA, Ryohei NISHIMURA

Source: Experimental Animals; 2023, Vol. 72 Issue 1, p19-29, 11p

Urinary lipid production profile in canine patients with splenic mass.

Authors: Taiki KIDA, Arisa YAMAZAKI, Tatsuro NAKAMURA, Koji KOBAYASHI, Sho YOSHIMOTO, Shingo MAEDA, Takayuki NAKAGAWA, Ryohei NISHIMURA, Takahisa MURATA

Source: Journal of Veterinary Medical Science; 2022, Vol. 84 Issue 11, p1480-1484, 5p

Subject Terms: FISH oils, LIQUID chromatography-mass spectrometry, UNSATURATED fatty acids, LIPIDS, ARACHIDONIC acid, EICOSAPENTAENOIC acid, DOCOSAHEXAENOIC acid