Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy

Authors: Ella N. Hoogenboezem, Shrusti S. Patel, Justin H. Lo, Ashley B. Cavnar, Lauren M. Babb, Nora Francini, Eva F. Gbur, Prarthana Patil, Juan M. Colazo, Danielle L. Michell, Violeta M. Sanchez, Joshua T. McCune, Jinqi Ma, Carlisle R. DeJulius, Linus H. Lee, Jonah C. Rosch, Ryan M. Allen, Larry D. Stokes, Jordan L. Hill, Kasey C. Vickers, Rebecca S. Cook, Craig L. Duvall

Source: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a8ad79f8d57c45aeac75fe1a848bd947

Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m6A consensus sequences

Authors: Jessica J. Abner, Jeffrey L. Franklin, Margaret A. Clement, Scott A. Hinger, Ryan M. Allen, Xiao Liu, Stefanie Kellner, Junzhou Wu, John Karijolich, Qi Liu, Kasey C. Vickers, Peter Dedon, Alissa M. Weaver, Robert J. Coffey, James G. Patton

Source: Heliyon, Vol 7, Iss 12, Pp e08519- (2021)

Subject Terms: miRNA, Base modification, Extracellular vesicle, m6A, RNA, Tumor microenvironment, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844021026220; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/0841125014be436eb18dc13a0b901a8c

The Endogenous Plasma Small RNAome of Rheumatoid Arthritis

Authors: Michelle J. Ormseth, Joseph F. Solus, Quanhu Sheng, Fei Ye, Haocan Song, Qiong Wu, Yan Guo, Annette M. Oeser, Ryan M. Allen, Kasey C. Vickers, C. Michael Stein

Source: ACR Open Rheumatology, Vol 2, Iss 2, Pp 97-105 (2020)

Subject Terms: Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/2578-5745

Access URL: https://doaj.org/article/6ffa8e1e3d13490db5ac7efa1792468f

ABCG1 regulates pulmonary surfactant metabolism in mice and men[S]

Authors: Thomas Q. de Aguiar Vallim, Elinor Lee, David J. Merriott, Christopher N. Goulbourne, Joan Cheng, Angela Cheng, Ayelet Gonen, Ryan M. Allen, Elisa N.D. Palladino, David A. Ford, Tisha Wang, Ángel Baldán, Elizabeth J. Tarling

Source: Journal of Lipid Research, Vol 58, Iss 5, Pp 941-954 (2017)

Subject Terms: cholesterol, phospholipid, lung, pulmonary alveolar proteinosis, ATP binding cassette transporter G1, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S002222752033830X; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/195fb965f0f14ca3bfe255e6d4389a1f

Transfer of Functional Cargo in Exomeres

Authors: Qin Zhang, James N. Higginbotham, Dennis K. Jeppesen, Yu-Ping Yang, Wei Li, Eliot T. McKinley, Ramona Graves-Deal, Jie Ping, Colleen M. Britain, Kaitlyn A. Dorsett, Celine L. Hartman, David A. Ford, Ryan M. Allen, Kasey C. Vickers, Qi Liu, Jeffrey L. Franklin, Susan L. Bellis, Robert J. Coffey

Source: Cell Reports, Vol 27, Iss 3, Pp 940-954.e6 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124719300178; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/59ef4fa003ab41ff8bc8accefc1d9ba8

Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins

Authors: Ryan M. Allen, Shilin Zhao, Marisol A. Ramirez Solano, Wanying Zhu, Danielle L. Michell, Yuhuan Wang, Yu Shyr, Praveen Sethupathy, MacRae F. Linton, Gregory A. Graf, Quanhu Sheng, Kasey C. Vickers

Source: Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)

Subject Terms: MicroRNA, high-throughput sequencing, small RNA, lipoprotein, HDL, bile, urine, APOB, extracellular RNA, exogenous RNA, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2001-3078

Access URL: https://doaj.org/article/7a35d40986b3418c892ee4a7ab71ad1e

miR‐33 controls the expression of biliary transporters, and mediates statin‐ and diet‐induced hepatotoxicity

Authors: Ryan M. Allen, Tyler J. Marquart, Carolyn J. Albert, Frederick J. Suchy, David Q.‐H. Wang, Meenakshisundaram Ananthanarayanan, David A. Ford, Ángel Baldán

Source: EMBO Molecular Medicine, Vol 4, Iss 9, Pp 882-895 (2012)

Subject Terms: ABCB11, ATP8B1, cholestasis, miR‐33, statins, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/1177072675c34235991023e1bd4b3081

Isolation of High-density Lipoproteins for Non-coding Small RNA Quantification

Authors: Danielle L. Michell, author¹, Ryan M. Allen, author¹, Stuart R. Landstreet, author¹, Shilin Zhao, author², Cynthia L. Toth, author¹, Quanhu Sheng, author³, Kasey C. Vickers, author^{1, 2}

Source: Journal of Visualized Experiments. (117)

Availability: http://www.jove.com/video/54488

Long‐term therapeutic silencing of miR‐33 increases circulating triglyceride levels and hepatic lipid accumulation in mice

Authors: Leigh Goedeke, Alessandro Salerno, Cristina M Ramírez, Liang Guo, Ryan M Allen, Xiaoke Yin, Sarah R Langley, Christine Esau, Amarylis Wanschel, Edward A Fisher, Yajaira Suárez, Angel Baldán, Manuel Mayr, Carlos Fernández‐Hernando

Source: EMBO Molecular Medicine, Vol 6, Iss 9, Pp 1133-1141 (2014)

Subject Terms: cholesterol, fatty acids, hepatic steatosis, microRNA, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/190874ed1f9b4d5a9823b1a368aeca58