Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration

Authors: Sharada Baindoor, Hesham A. Y. Gibriel, Morten T. Venø, Junyi Su, Elena Perez Morrissey, Elisabeth Jirström, Ina Woods, Aidan Kenny, Mariana Alves, Luise Halang, Paola Fabbrizio, Maria Bilen, Tobias Engel, Marion C. Hogg, Caterina Bendotti, Giovanni Nardo, Ruth S. Slack, Jørgen Kjems, Jochen H. M. Prehn

Source: Disease Models & Mechanisms, Vol 17, Iss 11 (2024)

Subject Terms: amyotrophic lateral sclerosis, frontotemporal dementia, parkinson's disease, tsrna, trf, tirna, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/17/11/dmm050870; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

Access URL: https://doaj.org/article/aa68c60e37434af3a7faea0e7a4952d4

PFTK1 kinase regulates axogenesis during development via RhoA activation

Authors: Yasmilde Rodríguez González, Fatemeh Kamkar, Paymaan Jafar-nejad, Suzi Wang, Dianbo Qu, Leticia Sanchez Alvarez, Dina Hawari, Margaret Sonnenfeld, Ruth S. Slack, Paul R. Albert, David S. Park, Alvin Joselin

Source: BMC Biology, Vol 21, Iss 1, Pp 1-23 (2023)

Subject Terms: PFTAIRE, Eip63E, Rho, Cyclin-dependent kinases, Axogenesis, Neuronal development, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/e34f15bb20044e1ea43c89a1c762ae7a

Early postnatal defects in neurogenesis in the 3xTg mouse model of Alzheimer’s disease

Authors: Yubing Liu, Maria Bilen, Marie-Michelle McNicoll, Richard A. Harris, Bensun C. Fong, Mohamed Ariff Iqbal, Smitha Paul, Janice Mayne, Krystal Walker, Jing Wang, Daniel Figeys, Ruth S. Slack

Source: Cell Death and Disease, Vol 14, Iss 2, Pp 1-10 (2023)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/5885f579bf504f1894be9d65e727933b

Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition

Authors: Doo Soon Im, Alvin Joselin, Devon Svoboda, Tesuya Takano, Maxime W. C. Rousseaux, Steve Callaghan, Ruth S. Slack, Shin-ichi Hisanaga, Roger J. Davis, David S. Park, Dianbo Qu

Source: BMC Biology, Vol 20, Iss 1, Pp 1-16 (2022)

Subject Terms: Axonal outgrowth, Cdk5, Itch, JIP1, Notch1, phosphorylation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/96f63e0ea73a4bf79a28c2d3433be87b

Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis

Authors: Marissa A. Lithopoulos, Xavier Toussay, Shumei Zhong, Liqun Xu, Shamimunisa B. Mustafa, Julie Ouellette, Moises Freitas-Andrade, Cesar H. Comin, Hayam A. Bassam, Adam N. Baker, Yiren Sun, Michael Wakem, Alvaro G. Moreira, Cynthia L. Blanco, Arul Vadivel, Catherine Tsilfidis, Steven R. Seidner, Ruth S. Slack, Diane C. Lagace, Jing Wang, Baptiste Lacoste, Bernard Thébaud

Source: The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)

Subject Terms: Neuroscience, Stem cells, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/b460101f4de54091bba25914881e2839

PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress

Authors: En Huang, Dianbo Qu, Tianwen Huang, Nicoletta Rizzi, Wassamon Boonying, Dorothy Krolak, Paolo Ciana, John Woulfe, Christine Klein, Ruth S. Slack, Daniel Figeys, David S. Park

Source: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/4ea42cdc1afd4b7ba93863559be370d3

Mitochondrial dynamics in neurodegeneration: from cell death to energetic states

Authors: Mireille Khacho, Ruth S. Slack

Source: AIMS Molecular Science, Vol 2, Iss 2, Pp 161-174 (2015)

Subject Terms: mitochondrial dynamics, cristae architecture, bioenergetics, ATP production, cell survival, neurodegeneration, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.aimspress.com/article/10.3934/molsci.2015.2.161/fulltext.html; https://doaj.org/toc/2372-028X; https://doaj.org/toc/2372-0301

Access URL: https://doaj.org/article/d9595ab72f454176b83f41be65fb5e49

Modeling Neuronal Death and Degeneration in Mouse Primary Cerebellar Granule Neurons

Authors: Matthew Laaper, author^{1, 2}, Takrima Haque, author¹, Ruth S. Slack, author³, Arezu Jahani-Asl, author^{1, 2, 4}

Source: Journal of Visualized Experiments. (129)

Availability: http://www.jove.com/video/55871

Induction of Protein Deletion Through In Utero Electroporation to Define Deficits in Neuronal Migration in Transgenic Models

Authors: Devon S. Svoboda, author¹, Alysen Clark, author¹, David S. Park, author¹, Ruth S. Slack, author¹

Source: Journal of Visualized Experiments. (95)

Availability: http://www.jove.com/video/51983

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Dining in with BCL-2: new guests at the autophagy table.

Authors: Marc Germain¹, Ruth S. Slack¹

Source: Clinical Science. 2009, Vol. 118 Issue 3, p173-181. 9p.

Subject Terms: *AUTOPHAGY, *B cells, *LYMPHOMAS, *NEURAL physiology, *GENETIC regulation, *PLANT nutrients, *NEURODEGENERATION, APOPTOSIS prevention

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