CD20 CAR T cells safely and reversibly ablate B cell follicles in a non-human primate model of HIV persistence

Authors: Bui, John K., Starke, Carly E., Poole, Nikhita H., Rust, Blake J., Jerome, Keith R., Kiem, Hans-Peter, Peterson, Christopher W.

Source: In Molecular Therapy 1 May 2024 32(5):1238-1251

Oral desensitization therapy for peanut allergy induces dynamic changes in peanut‐specific immune responses

Authors: Bajzik, Veronique, DeBerg, Hannah A., Garabatos, Nahir, Rust, Blake J., Obrien, Kimberly K., Nguyen, Quynh‐Anh, O'Rourke, Colin, Smith, Alex, Walker, Alex H., Quinn, Charlie, Gersuk, Vivian H., Farrington, Mary, Jeong, David, Vickery, Brian P., Adelman, Daniel C., Wambre, Erik

Source: Allergy. 77(8):2534-2548

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163051787.0x000001&indx=1&recIds=ETOCvdc_100163051787.0x000001

Immune inactivation of anti-simian immunodeficiency virus chimeric antigen receptor T cells in rhesus macaques

Authors: Haeseleer, Françoise, Fukazawa, Yoshinori, Park, Haesun, Varco-Merth, Benjamin, Rust, Blake J., Smedley, Jeremy V., Eichholz, Karsten, Peterson, Christopher W., Mason, Rosemarie, Kiem, Hans-Peter, Roederer, Mario, Picker, Louis J., Okoye, Afam A., Corey, Lawrence

Source: In Molecular Therapy - Methods & Clinical Development 10 September 2021 22:304-319

Envelope-Specific Adaptive Immunity following Transplantation of Hematopoietic Stem Cells Modified with VSV-G Lentivirus

Authors: Rust, Blake J., Becker, Pamela S., Chandrasekaran, Devikha, Kubek, Sara P., Peterson, Christopher W., Adair, Jennifer E., Kiem, Hans-Peter

Source: In Molecular Therapy - Methods & Clinical Development 11 December 2020 19:438-446

Robust expansion of HIV CAR T cells following antigen boosting in ART-suppressed nonhuman primates

Authors: Rust, Blake J. ¹, Kean, Leslie S. ², Colonna, Lucrezia ¹, Brandenstein, Katherine E. ¹, Poole, Nikhita H. ¹, Obenza, Willimark ¹, Enstrom, Mark R. ¹, Maldini, Colby R. ³, Ellis, Gavin I. ³, Fennessey, Christine M. ⁴, Huang, Meei-Li ⁵, Keele, Brandon F. ⁴, Jerome, Keith R. ^{5, 6}, Riley, James L. ³, Kiem, Hans-Peter ^{1, 1, 6, 7}, Peterson, Christopher W. ^{2, 1, 7}

Source: In Blood 8 October 2020 136(15):1722-1734

CAR T-cell therapy for cancer and HIV through novel approaches to HIV-associated haematological malignancies

Authors: Rust, Blake J, Kiem, Hans-Peter, Uldrick, Thomas S ^*

Source: In The Lancet Haematology September 2020 7(9):e690-e696

Shaping T Cell – B Cell Collaboration in the Response to Human Immunodeficiency Virus Type 1 Envelope Glycoprotein gp120 by Peptide Priming.

Authors: Steede, N. Kalaya¹, Rust, Blake J.¹, Hossain, Mohammad M.¹, Freytag, Lucy C.², Robinson, James E.³, Landry, Samuel J.¹ landry@tulane.edu

Source: PLoS ONE. Jun2013, Vol. 8 Issue 6, p1-17. 17p.

Subject Terms: *T cells, *B cells, *HIV, *GLYCOPROTEINS, *LABORATORY mice, *MICROBIOLOGY, *IMMUNE response

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Dynamics of antigen-specific T effector and T regulatory cell responses during pollen allergy season

Authors: Rust, Blake J., DeBerg, Hannah, Wambre, Erik R.

Source: Journal of allergy and clinical immunology. 141(2):AB205-AB205

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100065037370.0x000001&indx=1&recIds=ETOCvdc_100065037370.0x000001

Role of IL-33 in modulating human allergen specific CD4+ T cell responses

Authors: Garabatos, Nahir, Bajzik, Veronique, Rust, Blake J., Londei, Marco, Wambre, Erik R.

Source: journal of allergy and clinical immunology. 139(2):AB88-AB88

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100053700485.0x000001&indx=1&recIds=ETOCvdc_100053700485.0x000001

Dual assessment of peanut-specific effector and regulatory T cells in patients undergoing oral immunotherapy

Authors: Rust, Blake J., Bajzik, Veronique, Vickery, Brian P., Wambre, Erik R.

Source: journal of allergy and clinical immunology. 139(2):AB257-AB257

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100053697924.0x000001&indx=1&recIds=ETOCvdc_100053697924.0x000001

Renal Cell Carcinoma (RCC) Tumors Display Large Expansion of Double Positive (DP) CD4+CD8+ T Cells With Expression of Exhaustion Markers.

Authors: Menard, Laurence C., Fischer, Paul, Kakrecha, Bijal, Linsley, Peter S., Wambre, Erik, Liu, Maochang C., Rust, Blake J., Lee, Deborah, Penhallow, Becky, Manjarrez Orduno, Nataly, Nadler, Steven G.

Source: Frontiers in Immunology; 11/26/2018, pN.PAG-N.PAG, 13p

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CD20 CAR T-cells safely and reversibly ablate B-cell follicles in a nonhuman primate model of HIV persistence

Authors: Bui, John K., Starke, Carly E., Poole, Nikhita H., Rust, Blake J., Jerome, Keith R., Kiem, Hans-Peter, Peterson, Christopher W.

Source: Molecular Therapy; 20240101, Issue: Preprints

Anti-PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4⁺ T cells in germinal centers.

Authors: Eichholz, Karsten, Yoshinori Fukazawa, Peterson, Christopher W., Francoise, Francoise, Medina, Manuel, Hoffmeister, Shelby, Duel, Derick M., Varco-Merth, Benjamin D., Dross, Sandra, Haesun Park, Labriola, Caralyn S., Axthelm, Michael K., Murnane, Robert D., Smedley, Jeremy V., Lei Jin, Jiaxin Gong, Rust, Blake J., Fuller, Deborah H., Kiem, Hans-Peter, Picker, Louis J.

Source: Journal of Clinical Investigation. 4/1/2024, Vol. 134 Issue 7, p1-14. 14p.

Subjects: CHIMERIC antigen receptors, T cells, GERMINAL centers, IMMUNOLOGIC memory, IMMUNE checkpoint proteins

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