Molecular mechanisms restoring olaparib efficacy through ATR/CHK1 pathway inhibition in olaparib-resistant BRCA1/2MUT ovarian cancer models

Authors: Biegała, Łukasz, Statkiewicz, Małgorzata, Gajek, Arkadiusz, Szymczak-Pajor, Izabela, Rusetska, Natalia, Śliwińska, Agnieszka, Marczak, Agnieszka, Mikula, Michał, Rogalska, Aneta

Source: In BBA - Molecular Basis of Disease February 2025 1871(2)

MK-8776 and Olaparib Combination Acts Synergistically in Hepatocellular Carcinoma Cells, Demonstrating Lack of Adverse Effects on Liver Tissues in Ovarian Cancer PDX Model.

Authors: Bębenek, Wiktoria, Gajek, Arkadiusz, Marczak, Agnieszka, Malý, Jan, Smejkal, Jiří, Statkiewicz, Małgorzata, Rusetska, Natalia, Bryś, Magdalena, Rogalska, Aneta

Source: International Journal of Molecular Sciences; Jan2025, Vol. 26 Issue 2, p834, 21p

Subject Terms: CHECKPOINT kinase 1, LIVER cancer, HEPATOCELLULAR carcinoma, THERAPEUTICS, OVARIAN cancer

Succinate Dehydrogenase‐Deficient Renal Cancer Featuring Fructose‐1, 6‐Biphosphatase Loss, Pyruvate Kinase M2 Overexpression, and SWI/SNF Chromatin Remodeling Complex Aberrations: A Rare Case Report

Authors: Szymanski, Michal, Rusetska, Natalia, Jancewicz, Iga, Armatowska, Alicja, Ligaj, Marcin, Chrzan, Alicja, Hincza, Kinga, Kowalik, Artur, Mika, Pawel, Kisiel, Maciej, Zolnierek, Jakub, Kosior, Joanna, Demkow, Tomasz, Siedlecki, Janusz A., Sarnowski, Tomasz J., Sarnowska, Elzbieta

Source: Oncologist. 26(9):e1652-e1655

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129260709.0x000001&indx=1&recIds=ETOCvdc_100129260709.0x000001

SWI/SNF chromatin remodeling complex and glucose metabolism are deregulated in advanced bladder cancer

Authors: Stachowiak, Malgorzata, Szymanski, Michal, Ornoch, Anna, Jancewicz, Iga, Rusetska, Natalia, Chrzan, Alicja, Demkow, Tomasz, Siedlecki, Janusz A., Sarnowski, Tomasz J., Sarnowska, Elzbieta

Source: IUBMB life. 72(6):1175-1188

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107547546.0x000001&indx=1&recIds=ETOCvdc_100107547546.0x000001

The Expression of Cell Cycle-Related Genes in USP8 -Mutated Corticotroph Neuroendocrine Pituitary Tumors and Their Possible Role in Cell Cycle-Targeting Treatment.

Authors: Mossakowska, Beata Joanna¹ (AUTHOR), Rusetska, Natalia¹ (AUTHOR), Konopinski, Ryszard² (AUTHOR), Kober, Paulina¹ (AUTHOR), Maksymowicz, Maria³ (AUTHOR), Pekul, Monika³ (AUTHOR), Zieliński, Grzegorz⁴ (AUTHOR), Styk, Andrzej⁴ (AUTHOR), Kunicki, Jacek⁵ (AUTHOR), Bujko, Mateusz¹ (AUTHOR) mateusz.bujko@pib-nio.pl

Source: Cancers. Nov2022, Vol. 14 Issue 22, p5594. 15p.

Subject Terms: *PROTEINS, *PURINES, *GENE expression, *CELL cycle, *GENES, *NEUROENDOCRINE tumors, *PITUITARY tumors

Somatic mutation profiling of vulvar cancer: Exploring therapeutic targets

Authors: Zięba, Sebastian, Kowalik, Artur, Zalewski, Kamil, Rusetska, Natalia, Goryca, Krzysztof, Piaścik, Agata, Misiek, Marcin, Bakuła-Zalewska, Elwira, Kopczyński, Janusz, Kowalski, Kamil, Radziszewski, Jakub, Bidziński, Mariusz, Góźdź, Stanisław, Kowalewska, Magdalena

Source: In Gynecologic Oncology September 2018 150(3):552-561

Role of Vitamin D and Its Receptors in the Pathophysiology of Chronic Rhinosinusitis

Authors: Tomaszewska, Malgorzata, Sarnowska, Elzbieta, Rusetska, Natalia, Kowalik, Katarzyna, Sierdzinski, Janusz, Siedlecki, Janusz A., Badmaev, Vladimir, Stohs, Sidney J., Popko, Mariola

Source: Journal of the American College of Nutrition. 38(2):108-118

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087139921.0x000001&indx=1&recIds=ETOCvdc_100087139921.0x000001

Relevance of mutations in protein deubiquitinases genes and TP53 in corticotroph pituitary tumors.

Authors: kul, Monika Pe, Szczepaniak, Magdalena, Kober, Paulina, Rusetska, Natalia, Mossakowska, Beata J., Baluszek, Szymon, Kowalik, Artur, Maksymowicz, Maria, Zielinski, Grzegorz, Kunicki, Jacek, Witek, Przemysław, Bujko, Mateusz

Source: Frontiers in Endocrinology; 2024, p1-11, 11p

Subject Terms: PITUITARY tumors, NUCLEOTIDE sequencing, DEUBIQUITINATING enzymes, CUSHING'S syndrome, GENETIC mutation

Epigenetic Downregulation of Hsa-miR-193b-3p Increases Cyclin D1 Expression Level and Cell Proliferation in Human Meningiomas.

Authors: Kober, Paulina, Mossakowska, Beata Joanna, Rusetska, Natalia, Baluszek, Szymon, Grecka, Emilia, Konopiński, Ryszard, Matyja, Ewa, Oziębło, Artur, Mandat, Tomasz, Bujko, Mateusz

Source: International Journal of Molecular Sciences; Sep2023, Vol. 24 Issue 17, p13483, 14p

Subject Terms: GENE expression, CYCLINS, CELL proliferation, EPIGENETICS, INTRACRANIAL tumors, TUMOR suppressor proteins

Company/Entity: WORLD Health Organization

DNA methylation, combined with RNA sequencing, provide novel insight into molecular classification of chordomas and their microenvironment.

Authors: Baluszek, Szymon, Kober, Paulina, Rusetska, Natalia, Wągrodzki, Michał, Mandat, Tomasz, Kunicki, Jacek, Bujko, Mateusz

Source: Acta Neuropathologica Communications; 7/11/2023, Vol. 11 Issue 1, p1-20, 20p

Subject Terms: DNA methylation, RNA sequencing, GENE expression profiling, GENE expression, DNA analysis, GENE amplification

The expression of glucocorticoid and mineralocorticoid receptors in pituitary tumors causing Cushing's disease and silent corticotroph tumors.

Authors: Kober, Paulina, Rusetska, Natalia, Mossakowska, Beata J., Maksymowicz, Maria, Pękul, Monika, Zieliński, Grzegorz, Styk, Andrzej, Kunicki, Jacek, Działach, Łukasz, Witek, Przemysław, Bujko, Mateusz

Source: Frontiers in Endocrinology; 3/29/2023, Vol. 14, p1-10, 10p

Subject Terms: CUSHING'S syndrome, GLUCOCORTICOID receptors, MINERALOCORTICOID receptors, PITUITARY tumors, GENE expression, TUMOR classification, ADRENAL insufficiency

Transcriptomic Classification of Pituitary Neuroendocrine Tumors Causing Acromegaly.

Authors: Rymuza, Julia, Kober, Paulina, Rusetska, Natalia, Mossakowska, Beata J., Maksymowicz, Maria, Nyc, Aleksandra, Baluszek, Szymon, Zieliński, Grzegorz, Kunicki, Jacek, Bujko, Mateusz

Source: Cells (2073-4409); Dec2022, Vol. 11 Issue 23, p3846, 16p

Subject Terms: PITUITARY tumors, NEUROENDOCRINE tumors, ACROMEGALY, TRANSCRIPTOMES, GENE expression profiling, SOMATOTROPIN receptors

CXCR4/ACKR3/CXCL12 axis in the lymphatic metastasis of vulvar squamous cell carcinoma.

Authors: Rusetska, Natalia, Kowalski, Kamil, Zalewski, Kamil, Zięba, Sebastian, Bidziński, Mariusz, Goryca, Krzysztof, Kotowicz, Beata, Fuksiewicz, Malgorzata, Kopczynski, Janusz, Bakuła-Zalewska, Elwira, Kowalik, Artur, Kowalewska, Magdalena

Source: Journal of Clinical Pathology; May2022, Vol. 75 Issue 5, p324-332, 9p

Subject Terms: PROGRAMMED cell death 1 receptors, SQUAMOUS cell carcinoma, LYMPHATIC metastasis, STROMAL cell-derived factor 1, CHEMOKINE receptors, CXCR4 receptors, MEDICAL sciences

Succinate Dehydrogenase‐Deficient Renal Cancer Featuring Fructose‐1,6‐Biphosphatase Loss, Pyruvate Kinase M2 Overexpression, and SWI/SNF Chromatin Remodeling Complex Aberrations: A Rare Case Report.

Authors: Szymanski, Michal, Rusetska, Natalia, Jancewicz, Iga, Armatowska, Alicja, Ligaj, Marcin, Chrzan, Alicja, Hincza, Kinga, Kowalik, Artur, Mika, Pawel, Kisiel, Maciej, Zolnierek, Jakub, Kosior, Joanna, Demkow, Tomasz, Siedlecki, Janusz A., Sarnowski, Tomasz J., Sarnowska, Elzbieta

Source: Oncologist; Sep2021, Vol. 26 Issue 9, pe1652-e1655, 4p, 2 Color Photographs

Subject Terms: PHOSPHOTRANSFERASES, IMMUNOHISTOCHEMISTRY, FRUCTOSE, PHOSPHATASES, GENETIC testing, GENE expression, KIDNEY tumors, CHROMOSOME abnormalities, OXIDOREDUCTASES, SEX chromatin

The Search of miRNA Related to Invasive Growth of Nonfunctioning Gonadotropic Pituitary Tumors.

Authors: Boresowicz, Joanna, Kober, Paulina, Rusetska, Natalia, Maksymowicz, Maria, Paziewska, Agnieszka, Dąbrowska, Michalina, Zeber-Lubecka, Natalia, Kunicki, Jacek, Bonicki, Wiesław, Ostrowski, Jerzy, Siedlecki, Janusz A., Bujko, Mateusz

Source: International Journal of Endocrinology; 12/7/2020, p1-8, 8p

Subject Terms: PITUITARY tumors, MICRORNA, PROGNOSIS, CANCER invasiveness, PITUITARY gland

The expression of bitter taste receptor TAS2R38 in patients with chronic rhinosinusitis.

Authors: Zborowska-Piskadło, Karolina, Stachowiak, Małgorzata, Rusetska, Natalia, Sarnowska, Elżbieta, Siedlecki, Janusz, Dżaman, Karolina

Source: Archivum Immunologiae & Therapiae Experimentalis; Oct2020, Vol. 68 Issue 5, p1-8, 8p

The SWI/SNF complex in eosinophilic andnon-eosinophilic chronicrhinosinusitis.

Authors: Kowalik, Katarzyna, Waniewska-Leczycka, Martyna, Sarnowska, Elzbieta, Rusetska, Natalia, Ligaj, Marcin, Chrzan, Alicja, Popko, Mariola

Source: Rhinology Supplement; 2021 Supplement, Vol. 61, p307-309, 3p

Role of chromatin remodeling complex SWI/SNF and VDR in chronic rhinosinusitis.

Authors: Kowalik, Katarzyna, Waniewska-Łęczycka, Martyna, Sarnowska, Elżbieta, Rusetska, Natalia, Sierdziński, Janusz, Zagor, Mariola

Source: Advances in Clinical & Experimental Medicine; Mar2020, Vol. 29 Issue 3, p313-323, 11p

Subject Terms: VITAMIN D receptors, SINUSITIS, NASAL polyps, GLUCOCORTICOID receptors, CHOLECALCIFEROL

USP8 mutations in corticotroph adenomas determine a distinct gene expression profile irrespective of functional tumour status.

Authors: Bujko, Mateusz, Kober, Paulina, Boresowicz, Joanna, Rusetska, Natalia, Paziewska, Agnieszka, Dąbrowska, Michalina, Piaścik, Agata, Pękul, Monika, Zieliński, Grzegorz, Kunicki, Jacek, Bonicki, Wiesław, Ostrowski, Jerzy, Siedlecki, Janusz A., Maksymowicz, Maria

Source: European Journal of Endocrinology; Dec2019, Vol. 181 Issue 6, p615-627, 13p

Subject Terms: GENE expression profiling, TUMORS, ION transport (Biology), GENE expression, CELL adhesion, ACROMEGALY, PITUITARY cancer

Inflammatory Proteins HMGA2 and PRTN3 as Drivers of Vulvar Squamous Cell Carcinoma Progression.

Authors: Fatalska, Agnieszka¹ (AUTHOR) fataga@wp.pl, Rusetska, Natalia² (AUTHOR) natarusetska@gmail.com, Bakuła-Zalewska, Elwira³ (AUTHOR) elwirabz@onet.eu, Kowalik, Artur^4,5 (AUTHOR) arturko@onkol.kielce.pl, Zięba, Sebastian⁴ (AUTHOR) s.zieba@o2.pl, Wroblewska, Agnieszka⁶ (AUTHOR) agnwr@op.pl, Zalewski, Kamil^2,7,8 (AUTHOR) zalewski81@gmail.com, Goryca, Krzysztof^9,10 (AUTHOR) kgoryca@gmail.com, Domański, Dominik¹ (AUTHOR) dom.domanski@ibb.waw.pl, Kowalewska, Magdalena^2,11 (AUTHOR) magdalena.kowalewska@pib-nio.pl

Source: Cancers. Jan2021, Vol. 13 Issue 1, p27-27. 1p.

Subject Terms: *DISEASE progression, *PATIENT aftercare, *VULVA, *INFLAMMATION, *NUCLEAR proteins, *PROTEOLYTIC enzymes, *VULVAR tumors, *BLOOD collection, *RISK assessment, *TUMOR classification, *PROTEOMICS, *GENE expression, *MASS spectrometry, *IMMUNITY, *HUMAN microbiota, *TUMOR markers, *ONTOLOGIES (Information retrieval), *BACTERIAL diseases, *SQUAMOUS cell carcinoma, *PRECANCEROUS conditions, *PHENOTYPES, *DISEASE risk factors