CD19 occupancy with tafasitamab increases therapeutic index of CART19 cell therapy and diminishes severity of CRS

Authors: Sakemura, R. Leo, Manriquez Roman, Claudia, Horvei, Paulina, Siegler, Elizabeth L., Girsch, James H., Sirpilla, Olivia L., Stewart, Carli M., Yun, Kun, Can, Ismail, Ogbodo, Ekene J., Adada, Mohamad M., Bezerra, Evandro D., Kankeu Fonkoua, Lionel Aurelien, Hefazi, Mehrdad, Ruff, Michael W., Kimball, Brooke L., Mai, Long K., Huynh, Truc N., Nevala, Wendy K., Ilieva, Kristina, Augsberger, Christian, Patra-Kneuer, Maria, Schanzer, Jürgen, Endell, Jan, Heitmüller, Christina, Steidl, Stefan, Parikh, Sameer A., Ding, Wei, Kay, Neil E., Nowakowski, Grzegorz S., Kenderian, Saad S.

Source: In Blood 18 January 2024 143(3):258-271

Management and Long-Term Outcomes of Patients With Recurrent Stroke-Like Episodes After Cranial Radiotherapy

Authors: Neth, Bryan J., Lachance, Daniel H., Uhm, Joon H., Ruff, Michael W.

Source: Neurologist. 28(4):218-225

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191716676.0x000001&indx=1&recIds=ETOCvdc_100191716676.0x000001

Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma

Authors: Sakemura, Reona, Hefazi, Mehrdad, Siegler, Elizabeth L., Cox, Michelle J., Larson, Daniel P., Hansen, Michael J., Manriquez Roman, Claudia, Schick, Kendall J., Can, Ismail, Tapper, Erin E., Horvei, Paulina, Adada, Mohamad M., Bezerra, Evandro D., Kankeu Fonkoua, Lionel Aurelien, Ruff, Michael W., Nevala, Wendy K., Walters, Denise K., Parikh, Sameer A., Lin, Yi, Jelinek, Diane F., Kay, Neil E., Bergsagel, P. Leif, Kenderian, Saad S.

Source: Blood. 139(26):3708-3721

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183245141.0x000001&indx=1&recIds=ETOCvdc_100183245141.0x000001

Temporal Trends in Glioblastoma Survival

Authors: Neth, Bryan J., Carabenciov, Ivan D., Ruff, Michael W., Johnson, Derek R.

Source: Neurologist. 27(3):119-124

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100148873142.0x000001&indx=1&recIds=ETOCvdc_100148873142.0x000001

Bevacizumab exerts dose-dependent risk for intracranial hemorrhage in patients with malignant gliomas.

Authors: Lim, Sanghee, Clarke, Nathan H., Maloney, Sara L., Sener, Ugur T., Caron, Samantha J., Kizilbash, Sani H., Campian, Jian L., Neth, Bryan J., Carabenciov, Ivan D., Uhm, Joon, Ruff, Michael W.

Source: Journal of Neuro-Oncology; Mar2025, Vol. 172 Issue 1, p273-280, 8p

Recurrent adamantinomatous craniopharyngioma stabilized with tocilizumab and bevacizumab: illustrative case.

Authors: Webb, Lauren M., Okuno, Scott H., Ransom, Ryan C., Van Gompel, Jamie J., Humes, Allison L., Sarkaria, Jann N., Ruff, Michael W.

Source: Journal of Neurosurgery Case Lessons; Jan2025, Vol. 9 Issue 2, p1-6, 6p

Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia

Authors: Cox, Michelle J., Lucien, Fabrice, Sakemura, Reona, Boysen, Justin C., Kim, Yohan, Horvei, Paulina, Manriquez Roman, Claudia, Hansen, Michael J., Tapper, Erin E., Siegler, Elizabeth L., Forsman, Cynthia, Crotts, Sydney B., Schick, Kendall J., Hefazi, Mehrdad, Ruff, Michael W., Can, Ismail, Adada, Mohamad, Bezerra, Evandro, Kankeu Fonkoua, Lionel Aurelien, Nevala, Wendy K., Braggio, Esteban, Ding, Wei, Parikh, Sameer A., Kay, Neil E., Kenderian, Saad S.

Source: In Molecular Therapy 7 April 2021 29(4):1529-1540

Lack of drug interaction between levetiracetam and high‐dose methotrexate in patients with lymphoma

Authors: DeFino, Catherine E., Barreto, Jason N., Pawlenty, Amanda G., Ruff, Michael W., Carabenciov, Ivan D., Mara, Kristin C., Thompson, Carrie A.

Source: Pharmacotherapy. 41(5):430-439

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121087745.0x000001&indx=1&recIds=ETOCvdc_100121087745.0x000001

Pituitary adenomas in the setting of multiple endocrine neoplasia type 1: a single-institution experience

Authors: Cohen-Cohen, Salomon, Brown, Desmond A., Himes, Benjamin T., Wheeler, Lydia P., Ruff, Michael W., Major, Brittny T., Ospina, Naykky M. Singh, Atkinson, John L. D., Meyer, Fredric B., Bancos, Irina

Source: Journal of neurosurgery. 134(4):1132-1138

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626194447&indx=1&recIds=ETOCRN626194447

Diffuse Gliomas of the Brainstem and Cerebellum in Adults Show Molecular Heterogeneity

Authors: Eschbacher, Kathryn L., Ida, Cristiane M., Johnson, Derek R., Alvi, Mohammed A., Jenkins, Sarah M., Ruff, Michael W., Kerezoudis, Panagiotis, Neth, Bryan J., Pasion, Romela M., Daniels, David J., Kizilbash, Sani H., Raghunathan, Aditya

Source: American journal of surgical pathology. 45(8):1082-1090

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185885723.0x000001&indx=1&recIds=ETOCvdc_100185885723.0x000001

Safety of intravenous thrombolysis for ischemic stroke in patients with hematologic malignancies: A single institution experience

Authors: Rael, Sofia, Webb, Mason, Brown, Robert D., Ruff, Michael W., Keser, Zafer, Sener, Ugur

Source: Journal of stroke and cerebrovascular diseases. 32(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196359549.0x000001&indx=1&recIds=ETOCvdc_100196359549.0x000001

Enlarging Perivascular Spaces Following Radiation Therapy in the Brain: A Report of 2 Cases and Literature Review

Authors: Mark, Ian T., Carr, Carrie M., Ruff, Michael W., Flanagan, Eoin P., Johnson, Derek R.

Source: World neurosurgery. 138:436-439

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116656157.0x000001&indx=1&recIds=ETOCvdc_100116656157.0x000001

Temozolomide desensitization followed by metronomic dosing in patients with hypersensitivity

Authors: Neth, Bryan J., Ruff, Michael W., Uhm, Joon H., Johnson, Derek R., Divekar, Rohit D., Maddox, Daniel E.

Source: Cancer chemotherapy and pharmacology. 86(3):375-382

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167861411.0x000001&indx=1&recIds=ETOCvdc_100167861411.0x000001

Chimeric antigen receptor T-cell therapy associated hemophagocytic lymphohistiocytosis syndrome: clinical presentation, outcomes, and management.

Authors: Khurana, Arushi, Rosenthal, Allison C., Mohty, Razan, Gaddam, Mamatha, Bansal, Radhika, Hathcock, Matthew A., Nedved, Adrienne N., Durani, Urshila, Iqbal, Madiha, Wang, Yucai, Paludo, Jonas, Villasboas, J. C., Dingli, David, Kourelis, Taxiarchis, Leung, Nelson, Alkhateeb, Hassan, Ruff, Michael W., Gallo de Moraes, Alice, Vergidis, Paschalis, Herrmann, Joerg

Source: Blood Cancer Journal; 8/12/2024, Vol. 14 Issue 1, p1-6, 6p

Subject Terms: DIFFUSE large B-cell lymphomas, MANTLE cell lymphoma, CYTOKINE release syndrome, CHILD patients, B cell lymphoma, DIVERTICULITIS, INTESTINAL perforation

A case series of osseous metastases in patients with glioblastoma.

Authors: Webb, Lauren Michelle, Webb, Mason J., Campian, Jian L., Caron, Samantha J., Ruff, Michael W., Uhm, Joon H., Sener, Ugur

Source: Medicine; 7/5/2024, Vol. 103 Issue 27, p1-7, 7p

A Case of Long-Term Survival After Glioblastoma, IDH-Wild Type.

Authors: Webb, Lauren M., Neth, Bryan J., Raghunathan, Aditya, Greipp, Patricia T., Ida, Cristiane M., Carabenciov, Ivan D., Ruff, Michael W.

Source: Neurologist; Jul2024, Vol. 29 Issue 4, p254-258, 5p

Transient CD19 Occupancy with Tafasitamab at the Time of Anti-CD19 Chimeric Antigen Receptor T (CART19) Cell Infusion Diminishes Severity and Incidence of CRS and Improves the Therapeutic Index of CART19 Cell Therapy in Preclinical Models

Authors: Sakemura, R. Leo, Roman, Claudia Manriquez, Horvei, Paulina, Huynh, Truc N, Girsch, James H., Sirpilla, Olivia, Yun, Kun, Stewart, Carli M., Can, Ismail, Ogbodo, Ekene J., Adada, Mohamad M., Kankeu Fonkoua, Lionel Aurelien, Hefazi, Mehrdad, Ruff, Michael W., Ilieva-Babinsky, Kristina, Augsberger, Christian, Patra-Kneuer, Maria, Heitmüller, Christina, Steidl, Stefan, Parikh, Sameer A., Ding, Wei, Kay, Neil E., Nowakowski, Grzegorz S, Siegler, Elizabeth L., Kenderian, Saad S.

Source: Transplantation and Cellular Therapy. 29(S):S11-S12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180675821.0x000001&indx=1&recIds=ETOCvdc_100180675821.0x000001

Axicabtagene Ciloleucel Chimeric Antigen Receptor T Cell Therapy in Lymphoma With Secondary Central Nervous System Involvement

Authors: Novo, Mattia, Ruff, Michael W., Skrabek, Pamela J., Lin, Yi

Source: Mayo Clinic Proceedings. 94(11):2361-2364

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100091605057.0x000001&indx=1&recIds=ETOCvdc_100091605057.0x000001

Recurrent papillary craniopharyngioma with BRAF V600E mutation treated with dabrafenib: case report

Authors: Himes, Benjamin T., Ruff, Michael W., Van Gompel, Jaimie J., Park, Sean S., Galanis, Evanthia, Kaufmann, Timothy J., Uhm, Joon H.

Source: Journal of neurosurgery. 130(4):1299-1303

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN619533651&indx=1&recIds=ETOCRN619533651

A case of epidural glioblastoma metastasis presenting with a cervical myelopathy, torticollis, and L'hermitte's phenomenon

Authors: Ruff, Michael W., Bhargav, Adip G., Raghunathan, Aditya

Source: Brain tumor pathology. 35(3):181-185

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100126184668.0x000001&indx=1&recIds=ETOCvdc_100126184668.0x000001