Two or more significant life-events in 6-months are associated with lower rates of HIV treatment and virologic suppression among youth with HIV in Uganda and Kenya

Authors: Mwangwa, Florence, Charlebois, Edwin D., Ayieko, James, Olio, Winter, Black, Douglas, Peng, James, Kwarisiima, Dalsone, Kabami, Jane, Balzer, Laura B., Petersen, Maya L., Kapogiannis, Bill, Kamya, Moses R., Havlir, Diane V., Ruel, Theodore D.

Source: AIDS care. 35(1):95-105

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179691424.0x000001&indx=1&recIds=ETOCvdc_100179691424.0x000001

What babies need: accelerating access to current and novel antiretroviral drugs in neonates through pharmacokinetic studies

Authors: Burger, David, Bekker, Adrie, Cressey, Tim, Hirt, Deborah, Lutsar, Irja, Mcilleron, Helen, Standing, Joe, Van den Anker, John, Svensson, Elin, Abrams, Elaine, Amuge, Pauline, Archary, Mo, Belew, Yodit, Best, Brookie, Bygrave, Helen, Capparelli, Edmund, Casas, Esther, Clarke, Diana, Clayden, Polly, Colbers, Angela, Dangarembizi, Mutsa, De Lisa, Roberto, Denti, Paolo, Domanico, Paul, Essajee, Shaffiq, Frigati, Lisa, Giaquinto, Carlo, Gibb, Diana, Hackett, Stephanie, Hazra, Rohan, Lallemant, Marc, Lewis, Linda, Lockman, Shahin, Mahaka, Imelda, McFarland, Betsy, Meere, Cathal, Mir, Fatima, Mirochnick, Mark, Mofenson, Lynne, Mukui, Irene, Mushavi, Angela, Musiime, Victor, Namusoke-Magongo, Eleanor, Obimbo, Elisabeth, Ojoo, Mary Atieno, Parades, Roger, Perez-Casas, Carmen, Piccolis, Manuele, Pinto, Jorge, Puthanakit, Thanyawee, Rakhmanina, Natella, Reinisch, Annette, Rojo, Pablo, Rouzier, Vanessa, Ruel, Ted, Sam-Agudu, Nadia, Siberry, George, Simione, Teresa, Simon, Katie, Singh, Vindi, Solares, Manjari, Sugandhi, Nandita, Sylla, Mariam, Thior, Ibou, Turkova, Anna, Vicari, Marissa, Walsh, Jenny, Watkins, Melynda, Wolf, Hilary, Hafiz, Asma, Penazzato, Martina, Rangaraj, Ajay, Doherty, Meg, Vitoria, Marco, Jacobs, Tom G ^*, Schouwenburg, Stef, Archary, Moherndran, Ruel, Theodore D, van den Anker, John, Burger, David M, Cressey, Tim R, Abrams, Elaine J, Lyall, Hermione

Source: In The Lancet HIV September 2022 9(9):e649-e657

Advancing the prevention and treatment of HIV in children: priorities for research and development

Authors: Abrams, Elaine, Archary, Moherndran, Bekker, Adrie, Capparelli, Edmund, Colbers, Angela, Cressey, Tim, Frigati, Lisa, Hafiz, Asma, Mukui, Irene, Penazzato, Martina, Rakhmanina, Natella, Rojo, Pablo, Ruel, Theodore, Sam-Agudu, Nadia, Sugandhi, Nandita, Townsend, Claire, Vicari, Marissa, Watkins, Melynda, Townsend, Claire L, Sam-Agudu, Nadia A, Ruel, Theodore D, Cressey, Tim R, Capparelli, Edmund V, Abrams, Elaine J

Source: In The Lancet HIV September 2022 9(9):e658-e666

Pharmacokinetics, safety, tolerability, and antiviral activity of dolutegravir dispersible tablets in infants and children with HIV-1 (IMPAACT P1093): results of an open-label, phase 1–2 trial

Authors: Deville, Jaime G, Carter, Michele F, Mansky, Hannah, Pinto, Jorge A, Ferreira, Flavia F, Romeiro, Juliana, D'Angelo, Jessica, Williams, Ruth, Jundi, Fernanda, Cruz, Maria Letícia Santos, Sidi, Claude Leon, Kataike, Hajira, Owor, Maxensia, Ahimbisibwe, Grace Miriam, van Rensburg, Ms Anita Janse, Andrea, Catherine V, Ponatshego, Ponego L, Budu, Marian, Tirelo, Lesedi, Masheto, Gaerolwe R, Raesi, Mpho S., Ramogodiri, Moakanyi, Chanthong, Jiraporn, Khamrong, Chintana, Aurpibul, Linda, Fairlie, Lee, Patel, Faeezah, Soma-Kashiram, Hamisha, Archary, Moherndran, Hanley, Sherika, Govender, Vani, Sturzbecher, Fernanda Tomé, Cervi, Maria Célia, Mmbaga, Blandina T, Njau, Boniface, Matibe, Petronilla, Mukonowenzou, Ruvimbo, Marozva, Catherine C, Keter, Winnie C, Bii, Priscilla C, Ounchanum, Pradthana, Cressey, Tim R, Sukrakanchana, Pra-ornsuda, Chokephaibulkit, Kulkanya, Rungmaitree, Supattra, Pilotto, Jose Henrique, Fernandes, Luis Eduardo, Gomes, Ivete Martins, Ruel, Theodore D ^*, Acosta, Edward P, Liu, Jessica P, Gray, Kathryn P, George, Kathleen, Montañez, Nicole, Popson, Stephanie, Buchanan, Ann M, Bartlett, Mattie, Dayton, Dale, Anthony, Patricia, Brothers, Cynthia, Vavro, Cynthia, Singh, Rajendra, Koech, Lucy, Vhembo, Tichaona, Dobbels, Els F M, Hazra, Rohan, Townley, Ellen, Wiznia, Andrew

Source: In The Lancet HIV May 2022 9(5):e332-e340

Pharmacokinetics and safety of early nevirapine-based antiretroviral therapy for neonates at high risk for perinatal HIV infection: a phase 1/2 proof of concept study

Authors: Ruel, Theodore D ^*, Capparelli, Edmund V, Tierney, Camlin, Nelson, Bryan S, Coletti, Anne, Bryson, Yvonne, Cotton, Mark F, Spector, Stephen A, Mirochnick, Mark, LeBlanc, Rebecca, Reding, Christina, Zimmer, Bonnie, Persaud, Deborah, Bwakura-Dangarembizi, Mutsa, Naidoo, Kimesh L, Hazra, Rohan, Jean-Philippe, Patrick, Chadwick, Ellen G

Source: In The Lancet HIV March 2021 8(3):e149-e157

Lamivudine dosing for preterm infants exposed to HIV: a population pharmacokinetic modelling and simulation study.

Authors: Bekker, Adrie, Capparelli, Edmund V, Mirochnick, Mark, Clarke, Diana F, Cotton, Mark F, Shapiro, Roger, McCarthy, Katie, Moye, Jack, Violari, Avy, Chokephaibulkit, Kulkanya, Abrams, Elaine, Penazzato, Martina, Ruel, Theodore D, Cressey, Tim R

Source: Journal of Antimicrobial Chemotherapy (JAC); Oct2024, Vol. 79 Issue 10, p2570-2574, 5p

Subject Terms: NEWBORN infants, PREMATURE infants, LAMIVUDINE, GESTATIONAL age, INFANTS

Adolescent participation in HIV research: consortium experience in low and middle-income countries and scoping review

Authors: Day, Suzanne ^*, Kapogiannis, Bill G, Shah, Seema K, Wilson, Erin C, Ruel, Theodore D, Conserve, Donaldson F, Strode, Ann, Donenberg, Geri R, Kohler, Pamela, Slack, Catherine, Ezechi, Oliver, Tucker, Joseph D

Source: In The Lancet HIV December 2020 7(12):e844-e852

Uptake, engagement, and adherence to pre-exposure prophylaxis offered after population HIV testing in rural Kenya and Uganda: 72-week interim analysis of observational data from the SEARCH study

Authors: Koss, Catherine A ^*, Charlebois, Edwin D, Ayieko, James, Kwarisiima, Dalsone, Kabami, Jane, Balzer, Laura B, Atukunda, Mucunguzi, Mwangwa, Florence, Peng, James, Mwinike, Yusuf, Owaraganise, Asiphas, Chamie, Gabriel, Jain, Vivek, Sang, Norton, Olilo, Winter, Brown, Lillian B, Marquez, Carina, Zhang, Kevin, Ruel, Theodore D, Camlin, Carol S, Rooney, James F, Black, Douglas, Clark, Tamara D, Gandhi, Monica, Cohen, Craig R, Bukusi, Elizabeth A, Petersen, Maya L, Kamya, Moses R, Havlir, Diane V

Source: In The Lancet HIV April 2020 7(4):e249-e261

Prioritising the most needed paediatric antiretroviral formulations: the PADO4 list

Authors: Abrams, Elaine, Ananworanich, Jintanat, Andrieux-Meyer, Isabelle, Archary, Moherndran, Belew, Yodit, Best, Brookie, Bologna, Rosa, Burry, Jessica, Carpenter, Deborah, Cheng, Yao, Clayden, Polly, Colbers, Angela, Conway, Magda, Cressey, Timothy R., Dangarembizi, Mutsa, Essajee, Shaffiq, Gonzalez Tome, Maribel, Hill, Andrew, Khoo, Saye, Kim, Maria, Lewis, Linda, Lee, Janice, Lockman, Shahin, Mahaka, Imelda, Mirochnick, Mark H., Mofenson, Lynne, Muhimpundu, Mireille, Mushavi, Angela, Musiime, Victor, Obimbo, Elizabeth, Pascual, Fernando, Perez Casas, Carmen, Pozniak, Anton, Rabie, Helena, Rakhmanina, Natella, Rojo, Pablo, Ruel, Theodore, Schapiro, Jonathan, Siberry, George, Simione, Teresa Beatriz, Sugandhi, Nandita, Tidiane Tall, Cheick, Turkova, Anna, Venter, Francois, Vicari, Marissa, Walsh, Jenny, Wambui, Jacque, Watkins, Melynda, Penazzato, Martina, Townsend, Claire L, Cressey, Tim R, Kim, Maria H, Ruel, Theodore D, Doherty, Meg, Abrams, Elaine J

Source: In The Lancet HIV September 2019 6(9):e623-e631

Early Adopters of Human Immunodeficiency Virus Preexposure Prophylaxis in a Population-based Combination Prevention Study in Rural Kenya and Uganda

Authors: SEARCH Collaboration, Koss, Catherine A., Ayieko, James, Mwangwa, Florence, Owaraganise, Asiphas, Kwarisiima, Dalsone, Balzer, Laura B., Plenty, Albert, Sang, Norton, Kabami, Jane, Ruel, Theodore D., Black, Douglas, Camlin, Carol S., Cohen, Craig R., Bukusi, Elizabeth A., Clark, Tamara D., Charlebois, Edwin D., Petersen, Maya L., Kamya, Moses R., Havlir, Diane V.

Source: Clinical Infectious Diseases, 2018 Dec . 67(12), 1853-1860.

Access URL: https://www.jstor.org/stable/26573818

Gaps in the child tuberculosis care cascade in 32 rural communities in Uganda and Kenya

Authors: Mwangwa, Florence, Chamie, Gabriel, Kwarisiima, Dalsone, Ayieko, James, Owaraganise, Asiphas, Ruel, Theodore D., Plenty, Albert, Tram, Khai Hoan, Clark, Tamara D., Cohen, Craig R., Bukusi, Elizabeth A., Petersen, Maya, Kamya, Moses R., Charlebois, Edwin D., Havlir, Diane V., Marquez, Carina ^*

Source: In Journal of Clinical Tuberculosis and Other Mycobacterial Diseases December 2017 9:24-29

Impact of Genetic Variants in ABCG2, NR1I2, and UGT1A1 on the Pharmacokinetics of Dolutegravir in Children.

Authors: Spector, Stephen A., Brummel, Sean S., Chang, Audrey, Wiznia, Andrew, Ruel, Theodore D., Acosta, Edward P.

Source: JAIDS: Journal of Acquired Immune Deficiency Syndromes; Mar2024, Vol. 95 Issue 3, p297-303, 7p

Implementation of a neonatal transcutaneous bilirubin screening programme in rural India

Authors: Morgan, Melissa C., Kumar, G. S., Kaiser, Sunitha V., Seetharam, Sridevi, Ruel, Theodore D.

Source: Paediatrics and international child health. 36(2):122-126

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108690695.0x000001&indx=1&recIds=ETOCvdc_100108690695.0x000001

Brief Report: Food Insufficiency Is Associated With Lack of Sustained Viral Suppression Among HIV-Infected Pregnant and Breastfeeding Ugandan Women

Authors: Koss, Catherine A., Natureeba, Paul, Nyafwono, Dorcas, Plenty, Albert, Mwesigwa, Julia, Nzarubara, Bridget, Clark, Tamara D., Ruel, Theodore D., Achan, Jane, Charlebois, Edwin D., Cohan, Deborah, Kamya, Moses R., Havlir, Diane V., Young, Sera L.

Source: Journal of acquired immune deficiency syndromes. 71(3):310-315

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100036977069.0x000001&indx=1&recIds=ETOCvdc_100036977069.0x000001

Hair concentrations of antiretrovirals predict viral suppression in HIV-infected pregnant and breastfeeding Ugandan women

Authors: Koss, Catherine A., Natureeba, Paul, Mwesigwa, Julia, Cohan, Deborah, Nzarubara, Bridget, Bacchetti, Peter, Horng, Howard, Clark, Tamara D., Plenty, Albert, Ruel, Theodore D., Achan, Jane, Charlebois, Edwin D., Kamya, Moses R., Havlir, Diane V., Gandhi, Monica

Source: AIDS. 29(7):825-830

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100036754656.0x000001&indx=1&recIds=ETOCvdc_100036754656.0x000001

Neurocognitive and Motor Deficits in HIV-Infected Ugandan Children With High CD4 Cell Counts

Authors: Ruel, Theodore D., Boivin, Michael J., Boal, Hannah E., Bangirana, Paul, Charlebois, Edwin, Havlir, Diane V., Rosenthal, Philip J., Dorsey, Grant, Achan, Jane, Akello, Carolyne, Kamya, Moses R., Wong, Joseph K.

Source: Clinical Infectious Diseases, 2012 Apr 01. 54(7), 1001-1009.

Access URL: http://dx.doi.org/10.1093/cid/cir1037

Sex Differences in HIV RNA Level and CD4 Cell Percentage During Childhood

Authors: Ruel, Theodore D., Zanoni, Brian C., Ssewanyana, Isaac, Cao, Huyen, Havlir, Diane V., Kamya, Moses, Achan, Jane, Charlebois, Edwin D., Feeney, Margaret E.

Source: Clinical Infectious Diseases, 2011 Sep . 53(6), 592-599.

Access URL: http://dx.doi.org/10.1093/cid/cir484

Virologic and Immunologic Outcomes of HIV-Infected Ugandan Children Randomized to Lopinavir/Ritonavir or Nonnucleoside Reverse Transcriptase Inhibitor Therapy

Authors: Ruel, Theodore D., Kakuru, Abel, Ikilezi, Gloria, Mwangwa, Florence, Dorsey, Grant, Rosenthal, Philip J., Charlebois, Edwin, Havlir, Diane, Kamya, Moses, Achan, Jane

Source: Journal of acquired immune deficiency syndromes. 65(5):535-541

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100030456965.0x000001&indx=1&recIds=ETOCvdc_100030456965.0x000001

Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life.

Authors: Nelson, Bryan S, Tierney, Camlin, Persaud, Deborah, Jao, Jennifer, Cotton, Mark F, Bryson, Yvonne, Coletti, Anne, Ruel, Theodore D, Spector, Stephen A, Reding, Christina, Bacon, Kira, Costello, Diane, Perlowski, Charlotte, Cruz, Maria Leticia Santos, Kosgei, Josphat, Majji, Sai, Yin, Dwight E, Jean-Philippe, Patrick, Chadwick, Ellen G, Team, for the IMPAACT P1115

Source: Clinical Infectious Diseases; 2/1/2023, Vol. 76 Issue 3, pe744-e747, 4p

Subject Terms: HIV infections, CLINICAL trials, CONFIDENCE intervals, CROSS-sectional method, RESEARCH methodology, HIGHLY active antiretroviral therapy, CD4 lymphocyte count, DESCRIPTIVE statistics, RESEARCH funding, DATA analysis software, CHILDREN

Absence of neurocognitive disadvantage associated with paediatric HIV subtype A infection in children on antiretroviral therapy.

Authors: Bangirana, Paul¹, Ruel, Theodore D², Boivin, Michael J³, Pillai, Satish K^4,5, Giron, Leila B⁶, Sikorskii, Alla^3,7, Banik, Asish⁷, Achan, Jane⁸

Source: Journal of the International AIDS Society. 10/1/2017, Vol. 20, pn/a-n/a. 6p.

Subject Terms: *HIV infections, *HIGHLY active antiretroviral therapy, *NON-nucleoside reverse transcriptase inhibitors, *DNA, *GENE amplification