A murine experimental model of the pulmonary thrombotic effect induced by the venom of the snake Bothrops lanceolatus.

Authors: Rucavado, Alexandra¹ (AUTHOR), Camacho, Erika¹ (AUTHOR), Escalante, Teresa¹ (AUTHOR), Lomonte, Bruno¹ (AUTHOR), Fernández, Julián¹ (AUTHOR), Solano, Daniela¹ (AUTHOR), Quirós-Gutiérrez, Isabel¹ (AUTHOR), Ramírez-Vargas, Gabriel² (AUTHOR), Vargas, Karol² (AUTHOR), Argüello, Ivette² (AUTHOR), Navarro, Alejandro¹ (AUTHOR), Abarca, Carlos¹ (AUTHOR), Segura, Álvaro¹ (AUTHOR), Florentin, Jonathan³ (AUTHOR), Kallel, Hatem^4,5 (AUTHOR), Resiere, Dabor³ (AUTHOR), Neviere, Remi⁶ (AUTHOR), Gutiérrez, José María¹ (AUTHOR) jose.gutierrez@ucr.ac.cr

Source: PLoS Neglected Tropical Diseases. 10/02/2024, Vol. 18 Issue 10, p1-22. 22p.

Subject Terms: *SNAKE venom, *DISSEMINATED intravascular coagulation, *PARTIAL thromboplastin time, *ANTIVENINS, *VENOM, *SNAKEBITES

Neutralization, by a polyspecific antivenom, of the coagulopathy induced by the venom of Bothrops asper: Assessment by standard coagulation tests and rotational thromboelastometry in a murine model

Authors: Camacho, Erika ^a, Ramírez-Vargas, Gabriel ^b, Vargas, Karol ^b, Rucavado, Alexandra ^a, Escalante, Teresa ^a, Vargas, Mariángela ^a, Segura, Álvaro ^a, Argüello, Ivette ^b, Campos, Marlen ^b, Guerrero, German ^c, Méndez, Marilla Lamela ^d, Gutiérrez, José María ^{a, ∗}

Source: In Toxicon October 2023 234

A Complex Pattern of Gene Expression in Tissue Affected by Viperid Snake Envenoming: The Emerging Role of Autophagy-Related Genes.

Authors: Oliveira, Ana Karina de¹ (AUTHOR) ak4yj@virginia.edu, Rucavado, Alexandra² (AUTHOR) alexandra.rucavado@ucr.ac.cr, Escalante, Teresa² (AUTHOR) teresa.escalante@ucr.ac.cr, Gutiérrez, José María² (AUTHOR) jose.gutierrez@ucr.ac.cr, Fox, Jay W.³ (AUTHOR) jwf8x@virginia.edu

Source: Biomolecules (2218-273X). Mar2024, Vol. 14 Issue 3, p278. 18p.

Subject Terms: *SNAKE venom, *VENOM, *GENE expression, *FER-de-lance, *TRANSFORMING growth factors, *APOPTOSIS, *METABOLIC regulation

Geographic Terms: ASIA

Platelet depletion enhances lethal, hemorrhagic and myotoxic activities of Bothrops asper snake venom in a murine model

Authors: Ulloa-Fernández, Andrea, Escalante, Teresa, Gutiérrez, José María, Rucavado, Alexandra

Source: In Toxicon November 2022 219

Coagulopathy induced by viperid snake venoms in a murine model: Comparison of standard coagulation tests and rotational thromboelastometry

Authors: Rucavado, Alexandra, Chacón, Mariela, Villalobos, Daniela, Argüello, Ivette, Campos, Marlen, Guerrero, German, Méndez, Marilla Lamela, Escalante, Teresa, Gutiérrez, José María

Source: Toxicon. 214:121-129

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165465575.0x000001&indx=1&recIds=ETOCvdc_100165465575.0x000001

Platelet depletion does not alter the course of Brucella abortus infection in vivo

Authors: Arias-Gómez, Berny, Fonseca-Muñoz, Roger, Alfaro-Alarcón, Alejandro, Chacón-Díaz, Carlos, Moreno, Edgardo, Rucavado, Alexandra, Barquero-Calvo, Elías

Source: In Microbial Pathogenesis March 2022 164

Basement membrane degradation and inflammation play a role in the pulmonary hemorrhage induced by a P-III snake venom metalloproteinase

Authors: Castro, Ana Cristina, Escalante, Teresa, Rucavado, Alexandra, Gutiérrez, José María

Source: In Toxicon 15 July 2021 197:12-23

Changes in basement membrane components in an experimental model of skeletal muscle degeneration and regeneration induced by snake venom and myotoxic phospholipase A2

Authors: Escalante, Teresa, Saravia-Otten, Patricia, Gastaldello, Stefano, Hernández, Rosario, Marín, Alexa, García, Gabriela, García, Lourdes, Estrada, Erick, Rucavado, Alexandra, Gutiérrez, José María

Source: In Toxicon March 2021 192:46-56

Analysis of wound exudates reveals differences in the patterns of tissue damage and inflammation induced by the venoms of Daboia russelii and Bothrops asper in mice

Authors: Rucavado, Alexandra, Escalante, Teresa, Kalogeropoulos, Konstantinos, Camacho, Erika, Gutiérrez, José María, Fox, Jay W.

Source: In Toxicon 30 October 2020 186:94-104

Resistance of South American opossums to vWF-binding venom C-type lectins

Authors: Drabeck, Danielle H., Rucavado, Alexandra, Hingst-Zaher, Erika, Cruz, Yolanda P., Dean, Antony M., Jansa, Sharon A.

Source: In Toxicon 30 April 2020 178:92-99

Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms

Authors: Gutiérrez, José María, Rucavado, Alexandra, Escalante, Teresa, Herrera, Cristina, Fernández, Julián, Lomonte, Bruno, Fox, Jay W.

Source: In Toxicon 15 June 2018 148:123-131

Preclinical evaluation of the neutralizing ability of a monospecific antivenom for the treatment of envenomings by Bothrops lanceolatus in Martinique

Authors: Resiere, Dabor, Arias, Ana Silvia, Villalta, Mauren, Rucavado, Alexandra, Brouste, Yannick, Cabié, André, Névière, Rémi, Césaire, Raymond, Kallel, Hatem, Mégarbane, Bruno, Mehdaoui, Hossein, Gutiérrez, José María

Source: In Toxicon 15 June 2018 148:50-55

Ancestrally Reconstructed von Willebrand Factor Reveals Evidence for Trench Warfare Coevolution between Opossums and Pit Vipers

Authors: Drabeck, Danielle H, Rucavado, Alexandra, Hingst-Zaher, Erika, Dean, Antony, Jansa, Sharon A

Source: Molecular biology and evolution. 39(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100162696819.0x000001&indx=1&recIds=ETOCvdc_100162696819.0x000001

Comparison of biochemical and cytotoxic activities of extracts obtained from dorsal spines and caudal fin of adult and juvenile non-native Caribbean lionfish (Pterois volitans/miles)

Authors: Sáenz, Aránzazu, Ortiz, Natalia, Lomonte, Bruno, Rucavado, Alexandra, Díaz, Cecilia

Source: In Toxicon October 2017 137:158-167

Peptidomimetic hydroxamate metalloproteinase inhibitors abrogate local and systemic toxicity induced by Echis ocellatus (saw-scaled) snake venom

Authors: Arias, Ana Silvia, Rucavado, Alexandra, Gutiérrez, José María

Source: In Toxicon 15 June 2017 132:40-49

Hemorrhagic and procoagulant P-III snake venom metalloproteinases differ in their binding to the microvasculature of mouse cremaster muscle

Authors: Herrera, Cristina, Escalante, Teresa, Rucavado, Alexandra, Gutiérrez, José María

Source: Toxicon. 178:1-3

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114015806.0x000001&indx=1&recIds=ETOCvdc_100114015806.0x000001

Metalloproteinases in disease: identification of biomarkers of tissue damage through proteomics

Authors: Herrera, Cristina, Escalante, Teresa, Rucavado, Alexandra, Fox, Jay W., Gutiérrez, José María

Source: Expert review of proteomics. 15(12):967-982

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103564883.0x000001&indx=1&recIds=ETOCvdc_100103564883.0x000001

Discovery of small molecule inhibitors for the snake venom metalloprotease BaP1 using in silico and in vitro tests

Authors: Villalta-Romero, Fabian, Borro, Luiz, Mandic, Boris, Escalante, Teresa, Rucavado, Alexandra, Gutiérrez, Jose María, Neshich, Goran, Tasic, Ljubica

Source: Bioorganic & medicinal chemistry letters. 27(9):2018-2022

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100067919788.0x000001&indx=1&recIds=ETOCvdc_100067919788.0x000001

The lethality test used for estimating the potency of antivenoms against Bothrops asper snake venom: Pathophysiological mechanisms, prophylactic analgesia, and a surrogate in vitro assay

Authors: Chacón, Francisco, Oviedo, Andrea, Escalante, Teresa, Solano, Gabriela, Rucavado, Alexandra, Gutiérrez, José María

Source: In Toxicon January 2015 93:41-50

Isolation and characterization of four medium-size disintegrins from the venoms of Central American viperid snakes of the genera Atropoides, Bothrops, Cerrophidion and Crotalus

Authors: Angulo, Yamileth, Castro, Adriana, Lomonte, Bruno, Rucavado, Alexandra, Fernández, Julián, Calvete, Juan J., Gutiérrez, José María

Source: In Biochimie December 2014 107 Part B:376-384