Olgotrelvir, a dual inhibitor of SARS-CoV-2 Mpro and cathepsin L, as a standalone antiviral oral intervention candidate for COVID-19

Authors: Mao, Long, Shaabani, Namir, Zhang, Xiaoying, Jin, Can, Xu, Wanhong, Argent, Christopher, Kushnareva, Yulia, Powers, Colin, Stegman, Karen, Liu, Jia, Xie, Hui, Xu, Changxu, Bao, Yimei, Xu, Lijun, Zhang, Yuren, Yang, Haigang, Qian, Shengdian, Hu, Yong, Shao, Jianping, Zhang, Can, Li, Tingting, Li, Yi, Liu, Na, Lin, Zhenhao, Wang, Shanbo, Wang, Chao, Shen, Wei, Lin, Yuanlong, Shu, Dan, Zhu, Zhenhong, Kotoi, Olivia, Kerwin, Lisa, Han, Qing, Chumakova, Ludmila, Teijaro, John, Royal, Mike, Brunswick, Mark, Allen, Robert, Ji, Henry, Lu, Hongzhou, Xu, Xiao

Source: In Med 12 January 2024 5(1):42-61

Chapter 10 - Resiniferatoxin for permanent pain relief in cancer patients

Authors: Royal, Mike A.

Source: In TRP Channels as Therapeutic Targets Edition: Second Edition. 2024:155-162

Population pharmacokinetic-pharmacodynamic model of subcutaneous bupivacaine in a novel extended-release microparticle formulation.

Authors: Storgaard, Ida Klitzing, Jensen, Elisabeth Kjær, Bøgevig, Søren, Balchen, Torben, Springborg, Anders Holten, Royal, Mike Allan, Møller, Kirsten, Werner, Mads Utke, Lund, Trine Meldgaard

Source: Basic & Clinical Pharmacology & Toxicology; May2024, Vol. 134 Issue 5, p676-685, 10p

Subject Terms: POSTOPERATIVE pain treatment, BUPIVACAINE, PARALLEL processing

Dose safety and pharmacodynamics of subcutaneous bupivacaine in a novel extended-release microparticle formulation: A phase 1, dose-ascending study in male volunteers.

Authors: Jensen, Elisabeth Kjær, Bøgevig, Søren, Balchen, Torben, Springborg, Anders Holten, Royal, Mike Allan, Storgaard, Ida Klitzing, Lund, Trine Meldgaard, Møller, Kirsten, Werner, Mads Utke

Source: Basic & Clinical Pharmacology & Toxicology; May2024, Vol. 134 Issue 5, p657-675, 19p

Subject Terms: PHARMACODYNAMICS, DRUG side effects, SUBCUTANEOUS injections, CENTRAL nervous system, VOLUNTEERS, BUPIVACAINE, NALTREXONE

Let's walk together.

Authors: Royal, Mike

Source: Reform Magazine. Apr2022, p12-15. 4p.

Subject Terms: *CHARITIES, *CONGREGATIONALISM

Company/Entity: UNITED Reformed Church (Great Britain)

Novel delivery systems for postoperative analgesia

Authors: Palmer, Pamela P., Royal, Mike A., Miller, Ronald D.

Source: In Best Practice & Research Clinical Anaesthesiology March 2014 28(1):81-90

Reduced dose intravenous acetaminophen

Childhood asthma and use during pregnancy of acetaminophen. A critical review

Authors: Scialli, Anthony R., Ang, Robert, Breitmeyer, James, Royal, Mike A.

Source: In Reproductive Toxicology 2010 30(4):508-519

A review of the literature on the effects of acetaminophen on pregnancy outcome

Authors: Scialli, Anthony R., Ang, Robert, Breitmeyer, James, Royal, Mike A.

Source: In Reproductive Toxicology 2010 30(4):495-507

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Repeat-Dose Study of Two Intravenous Acetaminophen Dosing Regimens for the Treatment of Pain After Abdominal Laparoscopic Surgery

Authors: Wininger, Steven J., Miller, Howard, Minkowitz, Harold S., Royal, Mike A., Ang, Robert Y., Breitmeyer, James B., Singla, Neil K.

Source: In Clinical Therapeutics 2010 32(14):2348-2369

Contributors

Authors: Acharya, Tusar Kanta, Ahern, Gerard P., Al-Omari, Ammar, Ann, Jihyae, Aswin, Tanishaa, Banerjee, Anushka, Behrendt, Marc, Belvisi, Maria G., Bencze, Noémi, Bevan, Stuart, Bishnoi, Mahendra, Blumberg, Peter M., Bonvini, Sara J., Brain, Susan D., Campbell, James N., Cantero, María del Rocío, Cantiello, Horacio F., Chapman, Hugh, Charrua, A., Chung, Man-Kyo, Connolly, James, Cruz, F., Das, Nilesh Kumar, De Logu, Francesco, Dubey, Nishant Kumar, Erin, Nuray, Fallah, Hamideh P., Geppetti, Pierangelo, Goswami, Luna, Goswami, Chandan, Halder, Ramizur Rahaman, He, Qian, Helyes, Zsuzsanna, Holm, Patrik, Huang, Huizhen, Hudhud, Lina, Iannone, Luigi Francesco, Islas, Leon D., Jaffal, Sahar Majdi, Jalava, Niina, Kashio, Makiko, Kiselyov, Kirill, Koivisto, Ari, Konkoly, János, Kormos, Viktória, Kovács-Rozmer, Katalin, Kriszta, Gábor, Kuhad, Anurag, Kumar, Shamit, Kumar, Vikash, Kumar, Satish, Kumar, Abhishek, Lal, Roshan, Leavell, Yaowaree, Lee, Jeewoo, Liang, Dong, Liu, Yusheng, Lopez, Kyle E., Lyu, Yihan, Mahapatra, Parnasree, McKemy, David D., Mishra, Subham, Mohanta, Sushama, Nadezhdin, Kirill D., Nassini, Romina, Oláh, Attila, Patel, Mihir, Pepelyayeva, Yuliya, Pertovaara, Antti, Phan, Thieu X., Pintér, Erika, Pires, Paulo W., Pohóczky, Krisztina, Porszász, Robert, Pozsgai, Gábor, Puri, Priyanka, Rangel-Yescas, Gisela E., Rantanen, Marja, Rardin, Benjamin, Rokade, Tejas Pravin, Rosenberg, Paul, Ross, Sarah E., Royal, Mike A., Sahu, Ram Prasad, Savu, Andrea, Shikha, Deep, Silva, Josiane F., Simpson, David, Sing, Raima, Snyder, Lindsey M., Sobolevsky, Alexander I., Sodhi, Rupinder Kaur, Stevens, Randall, Szallasi, Arpad, Szőke, Éva, Szöllősi, Attila Gábor, Tóth, Attila, Tóth, Balázs István, Van Horn, Wade D., Wang, Hongmei, Wortley, Michael A., Zhang, Jinwei, Zhou, Zirui

Source: In TRP Channels as Therapeutic Targets Edition: Second Edition. 2024:xv-xviii

SOR-CART-MM-001 Study: A Phase I, Open-Label, Dose-Escalation, Pharmacokinetic, and Pharmacodynamic Study of Safety and Efficacy of CAR2 Anti-CD38 A2 CAR-T Cells in Patients with Relapsed or Refractory Multiple Myeloma (RRMM)

Authors: Stadtmauer, Edward A., Elghawy, Omar, Roberts, Todd F., Madduri, Deepu, Ailawadhi, Sikander, Royal, Mike, Yan, Ying

Source: In Blood 2 November 2023 142 Supplement 1:6851-6851

REDUCED DOSE INTRAVENOUS ACETAMINOPHEN

Developing patient-reported outcome measures for pain clinical trials: IMMPACT recommendations

Authors: Turk, Dennis C., Dworkin, Robert H., Burke, Laurie B., Gershon, Richard, Rothman, Margaret, Scott, Jane, Allen, Robert R., Atkinson, J. Hampton, Chandler, Julie, Cleeland, Charles, Cowan, Penny, Dimitrova, Rozalina, Dionne, Raymond, Farrar, John T., Haythornthwaite, Jennifer A., Hertz, Sharon, Jadad, Alejandro R., Jensen, Mark P., Kellstein, David, Kerns, Robert D., Manning, Donald C., Martin, Susan, Max, Mitchell B., McDermott, Michael P., McGrath, Patrick, Moulin, Dwight E., Nurmikko, Turo, Quessy, Steve, Raja, Srinivasa, Rappaport, Bob A., Rauschkolb, Christine, Robinson, James P., Royal, Mike A., Simon, Lee, Stauffer, Joseph W., Stucki, Gerold, Tollett, Jane, von Stein, Thorsten, Wallace, Mark S., Wernicke, Joachim, White, Richard E., Williams, Amanda C., Witter, James, Wyrwich, Kathleen W.

Source: In Pain 2006 125(3):208-215

Core outcome measures for chronic pain clinical trials: IMMPACT recommendations

Authors: Dworkin, Robert H. ^*, Turk, Dennis C., Farrar, John T., Haythornthwaite, Jennifer A., Jensen, Mark P., Katz, Nathaniel P., Kerns, Robert D., Stucki, Gerold, Allen, Robert R., Bellamy, Nicholas, Carr, Daniel B., Chandler, Julie, Cowan, Penney, Dionne, Raymond, Galer, Bradley S., Hertz, Sharon, Jadad, Alejandro R., Kramer, Lynn D., Manning, Donald C., Martin, Susan, McCormick, Cynthia G., McDermott, Michael P., McGrath, Patrick, Quessy, Steve, Rappaport, Bob A., Robbins, Wendye, Robinson, James P., Rothman, Margaret, Royal, Mike A., Simon, Lee, Stauffer, Joseph W., Stein, Wendy, Tollett, Jane, Wernicke, Joachim, Witter, James

Source: In Pain 2005 113(1):9-19

Botulinum toxins in pain management

Authors: Royal, Mike A.

Source: In Physical Medicine & Rehabilitation Clinics of North America 2003 14(4):805-820

Core outcome domains for chronic pain clinical trials: IMMPACT recommendations

Authors: Turk, Dennis C ^∗, Dworkin, Robert H, Allen, Robert R, Bellamy, Nicholas, Brandenburg, Nancy, Carr, Daniel B, Cleeland, Charles, Dionne, Raymond, Farrar, John T, Galer, Bradley S, Hewitt, David J, Jadad, Alejandro R, Katz, Nathaniel P, Kramer, Lynn D, Manning, Donald C, McCormick, Cynthia G, McDermott, Michael P, McGrath, Patrick, Quessy, Steve, Rappaport, Bob A, Robinson, James P, Royal, Mike A, Simon, Lee, Stauffer, Joseph W, Stein, Wendy, Tollett, Jane, Witter, James

Source: In Pain 2003 106(3):337-345

A Phase 1, Open-Label, Dose-Escalation Study of the Safety and Efficacy of Anti-CD38 Antibody Drug Conjugate (STI-6129) in Patients with Relapsed or Refractory Multiple Myeloma

Authors: Chakraborty, Rajshekhar, Yan, Ying, Royal, Mike

Source: In Blood 23 November 2021 138 Supplement 1:4763-4763

Confusion: Acetaminophen Dosing Changes Based on NO Evidence in Adults.

Authors: Krenzelok, Edward P.^1,2 krenzelokep@upmc.edu, Royal, Mike A.^3,4

Source: Drugs in R&D. 2012, Vol. 12 Issue 2, p45-48. 4p.

Subject Terms: *ACETAMINOPHEN, *DRUG prescribing, *OPIOIDS, *HEPATOTOXICOLOGY, *DOSAGE forms of drugs

Company/Entity: UNITED States. Food & Drug Administration

A Literature Review of Randomized Clinical Trials of Intravenous Acetaminophen (Paracetamol) for Acute Postoperative Pain.

Authors: Macario, Alex¹, Royal, Mike A.²

Source: Pain Practice. May/Jun2011, Vol. 11 Issue 3, p290-296. 7p. 1 Chart.

Subject Terms: *RESEARCH methodology evaluation, *ACETAMINOPHEN, *COMPARATIVE studies, *INFORMATION storage & retrieval systems, *MEDICAL databases, *INTRAVENOUS therapy, *LONGITUDINAL method, *MEDLINE, *HEALTH outcome assessment, *POSTOPERATIVE pain, *RESEARCH funding, *OPERATIVE surgery, *RANDOMIZED controlled trials, *TREATMENT effectiveness, *ADULTS