Immune landscape of oncohistone-mutant gliomas reveals diverse myeloid populations and tumor-promoting function

Authors: Augusto Faria Andrade, Alva Annett, Elham Karimi, Danai Georgia Topouza, Morteza Rezanejad, Yitong Liu, Michael McNicholas, Eduardo G. Gonzalez Santiago, Dhana Llivichuzhca-Loja, Arne Gehlhaar, Selin Jessa, Antonella De Cola, Bhavyaa Chandarana, Caterina Russo, Damien Faury, Geoffroy Danieau, Evan Puligandla, Yuhong Wei, Michele Zeinieh, Qing Wu, Steven Hebert, Nikoleta Juretic, Emily M. Nakada, Brian Krug, Valerie Larouche, Alexander G. Weil, Roy W. R. Dudley, Jason Karamchandani, Sameer Agnihotri, Daniela F. Quail, Benjamin Ellezam, Liza Konnikova, Logan A. Walsh, Manav Pathania, Claudia L. Kleinman, Nada Jabado

Source: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/69253d46aa2e495fb76b6cda5b46af80

An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders

Authors: Marie-France Dorion, Diana Casas, Irina Shlaifer, Moein Yaqubi, Peter Fleming, Nathan Karpilovsky, Carol X.-Q. Chen, Michael Nicouleau, Valerio E. C. Piscopo, Emma J. MacDougall, Aeshah Alluli, Taylor M. Goldsmith, Alexandria Schneider, Samuel Dorion, Nathalia Aprahamian, Adam MacDonald, Rhalena A. Thomas, Roy W. R. Dudley, Jeffrey A. Hall, Edward A. Fon, Jack P. Antel, Jo Anne Stratton, Thomas M. Durcan, Roberta La Piana, Luke M. Healy

Source: Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-26 (2024)

Subject Terms: Microglia, iPSC, ALSP, CSF1R, Inflammation, Phagocytosis, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/1750-1326

Access URL: https://doaj.org/article/aa6be16cdc4045c0b1747096bb52aa8a

Regulation of stress granule formation in human oligodendrocytes

Authors: Florian Pernin, Qiao-Ling Cui, Abdulshakour Mohammadnia, Milton G. F. Fernandes, Jeffery A. Hall, Myriam Srour, Roy W. R. Dudley, Stephanie E. J. Zandee, Wendy Klement, Alexandre Prat, Hannah E. Salapa, Michael C. Levin, G. R. Wayne Moore, Timothy E. Kennedy, Christine Vande Velde, Jack P. Antel

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7ecd4f332096485d86164c4aeb9e24fc

Vasospasm following brain tumor resection in children: institutional experience and systematic review

Authors: Bokhari, Rakan, Elkaim, Lior M., Shlobin, Nathan A., Alotaibi, Naif M., Sabbagh, Abdulrahman J., Weil, Alexander G., Baeesa, Saleh, Dudley, Roy W. R., Atkinson, Jeffrey, Farmer, Jean-Pierre

Source: Journal of neurosurgery.Pediatrics. 32(3):343-350

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633441867&indx=1&recIds=ETOCRN633441867

Hair-sparing approach versus traditional hair clipping for cerebral spinal fluid shunt procedures: a retrospective comparative study.

Authors: Arfaie, Saman, Sarabi, Ali, Solgi, Arad, Michaud, Eve, Rohr, Eliana, Giampa, Luca, Ieropoli, Elyssia, Lasry, Oliver, Dudley, Roy W. R.

Source: Journal of Neurosurgery: Pediatrics; Feb2025, Vol. 35 Issue 2, p158-166, 9p

Early administration of L‐arginine in mdx neonatal mice delays the onset of muscular dystrophy in tibialis anterior (TA) muscle

Authors: Roy W. R. Dudley, Alain S. Comtois, David H. St‐Pierre, Gawiyou Danialou

Source: FASEB BioAdvances, Vol 3, Iss 8, Pp 639-651 (2021)

Subject Terms: L‐arginine, mdx, neonates, nitric oxide, utrophin, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2573-9832

Access URL: https://doaj.org/article/c296dd0e573b493c9639fae57959f01b

Comparison of the real‐world effectiveness of vertical versus lateral functional hemispherotomy techniques for pediatric drug‐resistant epilepsy: A post hoc analysis of the HOPS study

Authors: Fallah, Aria, Lewis, Evan, Ibrahim, George M., Kola, Olivia, Tseng, Chi‐Hong, Harris, William B., Chen, Jia‐Shu, Lin, Kao‐Min, Cai, Li‐Xin, Liu, Qing‐Zhu, Lin, Jiu‐Luan, Zhou, Wen‐Jing, Mathern, Gary W., Smyth, Matthew D., O'Neill, Brent R., Dudley, Roy W. R., Ragheb, John, Bhatia, Sanjiv, Delev, Daniel, Ramantani, Georgia, Zentner, Josef, Wang, Anthony C., Dorfer, Christian, Feucht, Martha, Czech, Thomas, Bollo, Robert J., Issabekov, Galymzhan, Zhu, Hongwei, Connolly, Mary, Steinbok, Paul, Zhang, Jian‐Guo, Zhang, Kai, Hidalgo, Eveline Teresa, Weiner, Howard L., Wong‐Kisiel, Lily, Lapalme‐Remis, Samuel, Tripathi, Manjari, Sarat Chandra, Poodipedi, Hader, Walter, Wang, Feng‐Peng, Yao, Yi, Champagne, Pierre‐Olivier, Brunette‐Clément, Tristan, Guo, Qiang, Li, Shao‐Chun, Budke, Marcelo, Pérez‐Jiménez, Maria Angeles, Raftopoulos, Christian, Finet, Patrice, Michel, Pauline, Schaller, Karl, Stienen, Martin N., Baro, Valentina, Cantillano Malone, Christian, Pociecha, Juan, Chamorro, Noelia, Muro, Valeria L., Lehe, Marec, Vieker, Silvia, Oluigbo, Chima, Gaillard, William D., Al‐Khateeb, Mashael, Al Otaibi, Faisal, Krayenbühl, Niklaus, Bolton, Jeffrey, Pearl, Phillip L., Weil, Alexander G.

Source: Epilepsia. 62(11):2707-2718

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139822446.0x000001&indx=1&recIds=ETOCvdc_100139822446.0x000001

Early administration of L‐arginine in mdx neonatal mice delays the onset of muscular dystrophy in tibialis anterior (TA) muscle

Authors: Dudley, Roy W. R., Comtois, Alain S., St‐Pierre, David H., Danialou, Gawiyou

Source: FASEB bioAdvances. 3(8):639-651

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100124898958.0x000001&indx=1&recIds=ETOCvdc_100124898958.0x000001

Successful treatment of non-midline primary malignant germ cell tumors with yolk sac components in neonates: report of 2 cases

Authors: Weil, Alexander G., Mathews, Natalie, Farmer, Jean-Pierre, St. Martin, Christine, Albrecht, Steffen, Jabado, Nada, Dudley, Roy W. R.

Source: Journal of neurosurgery.Pediatrics. 27(1):47-51

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625559340&indx=1&recIds=ETOCRN625559340

Bilateral Parietal Skull Fractures in Infants Attributable to Accidental Falls

Authors: AlSahlawi, Aysha, Morantz, Gillian, Lacroix, Caroline, Saint-Martin, Christine, Dudley, Roy W. R.

Source: Pediatric neurosurgery. 56(5):424-431

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128776594.0x000001&indx=1&recIds=ETOCvdc_100128776594.0x000001

Spontaneous recovery of postsurgical progressive cervical spine kyphosis following intramedullary spinal cord tumor resection in a 4-year-old boy: illustrative case.

Authors: Michaud, Eve, Bokhari, Rakan, Saint-Martin, Christine, Saran, Neil, Dudley, Roy W. R.

Source: Journal of Neurosurgery Case Lessons; 10/28/2024, Vol. 8 Issue 18, p1-7, 7p

Individual-patient prediction of meningioma malignancy and survival using the Surveillance, Epidemiology, and End Results database

Authors: Jeremy T. Moreau, Todd C. Hankinson, Sylvain Baillet, Roy W. R. Dudley

Source: npj Digital Medicine, Vol 3, Iss 1, Pp 1-10 (2020)

Subject Terms: Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://doaj.org/toc/2398-6352

Access URL: https://doaj.org/article/8c580cb80a094cad8e4a04fe593e6768

Associations of Cerebral Blood Flow Patterns With Gray and White Matter Structure in Patients With Temporal Lobe Epilepsy.

Authors: Ngo, Alexander, Royer, Jessica, Rodriguez-Cruces, Raul, Ke Xie, DeKraker, Jordan, Auer, Hans, Tavakol, Shahin, Lam, Jack, Schrader, Dewi V., Dudley, Roy W. R., Bernasconi, Andrea, Bernasconi, Neda, Frauscher, Birgit, Lariviere, Sara, Bernhardt, Boris C.

Source: Neurology; 8/13/2024, Vol. 103 Issue 3, p1-13, 13p

Hydrocephalus-induced neurogenic stunned myocardium and cardiac arrest in a child: completely reversed with CSF diversion

Authors: Crevier-Sorbo, Gabriel, Atkinson, Jeffrey, Di Genova, Tanya, Puligandla, Pramod, Dudley, Roy W. R.

Source: Journal of neurosurgery.Pediatrics. 24(1):35-40

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620618145&indx=1&recIds=ETOCRN620618145

Utility of genetic testing in the pre-surgical evaluation of children with drug-resistant epilepsy.

Authors: Alsubhi, Sarah, Berrahmoune, Saoussen, Dudley, Roy W. R., Dufresne, David, Simard Tremblay, Elisabeth, Srour, Myriam, Myers, Kenneth A.

Source: Journal of Neurology; May2024, Vol. 271 Issue 5, p2503-2508, 6p

Subject Terms: PEDIATRIC surgery, CHILDREN with epilepsy, GENETIC testing, CHILDHOOD epilepsy, CHILD patients, PARTIAL epilepsy, MOLECULAR diagnosis, CHROMOSOME duplication

An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders.

Authors: Dorion, Marie-France, Casas, Diana, Shlaifer, Irina, Yaqubi, Moein, Fleming, Peter, Karpilovsky, Nathan, Chen, Carol X.-Q., Nicouleau, Michael, Piscopo, Valerio E. C., MacDougall, Emma J., Alluli, Aeshah, Goldsmith, Taylor M., Schneider, Alexandria, Dorion, Samuel, Aprahamian, Nathalia, MacDonald, Adam, Thomas, Rhalena A., Dudley, Roy W. R., Hall, Jeffrey A., Fon, Edward A.

Source: Molecular Neurodegeneration; 4/5/2024, Vol. 19 Issue 1, p1-26, 26p

Subject Terms: STEM cells, MACROPHAGE colony-stimulating factor, PURINERGIC receptors, MICROGLIA

Pediatric versus adult meningioma: comparison of epidemiology, treatments, and outcomes using the Surveillance, Epidemiology, and End Results database

Authors: Dudley, Roy W. R., Torok, Michelle R., Randall, Sarah, Béland, Benjamin, Handler, Michael H., Mulcahy-Levy, Jean M., Liu, Arthur K., Hankinson, Todd C.

Source: Journal of neuro-oncology. 137(3):621-629

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100118724484.0x000001&indx=1&recIds=ETOCvdc_100118724484.0x000001

Regulation of stress granule formation in human oligodendrocytes.

Authors: Pernin, Florian, Cui, Qiao-Ling, Mohammadnia, Abdulshakour, Fernandes, Milton G. F., Hall, Jeffery A., Srour, Myriam, Dudley, Roy W. R., Zandee, Stephanie E. J., Klement, Wendy, Prat, Alexandre, Salapa, Hannah E., Levin, Michael C., Moore, G. R. Wayne, Kennedy, Timothy E., Vande Velde, Christine, Antel, Jack P.

Source: Nature Communications; 2/22/2024, Vol. 15 Issue 1, p1-16, 16p

MerTK is a mediator of alpha-synuclein fibril uptake by human microglia.

Authors: Dorion, Marie-France^1,2,3, Yaqubi, Moein^2,3, Senkevich, Konstantin^4,5, Kieran, Nicholas W², MacDonald, Adam^2,3, Chen, Carol X Q^1,3, Luo, Wen^1,3, Wallis, Amber⁶, Shlaifer, Irina^1,3, Hall, Jeffery A³, Dudley, Roy W R⁷, Glass, Ian A⁸, Laboratory, Birth Defects Research, Stratton, Jo Anne^2,3, Fon, Edward A^1,3,4, Bartels, Tim⁶, Antel, Jack P^2,3, Gan-or, Ziv^4,5, Durcan, Thomas M^1,3, thomas.durcan@mcgill.ca, Healy, Luke M^2,3, luke.healy@mcgill.ca

Source: Brain: A Journal of Neurology; Feb2024, Vol. 147 Issue 2, p427-443, 17p

The Emergence of Zoonotic Onchocerca lupi Infection in the United States – A Case-Series

Authors: Cantey, Paul T., Weeks, Jessica, Edwards, Morven, Rao, Suchitra, Ostovar, G. Amin, Dehority, Walter, Alzona, Maria, Swoboda, Sara, Christiaens, Brooke, Ballan, Wassim, Hartley, John, Terranella, Andrew, Weatherhead, Jill, Dunn, James J., Marx, Douglas P., Hicks, M. John, Rauch, Ronald A., Smith, Christiana, Dishop, Megan K., Handler, Michael H., Dudley, Roy W. R., Chundu, Kote, Hobohm, Dan, Feiz-Erfan, Iman, Hakes, Joseph, Berry, Ryan S., Stepensaski, Shelly, Greenfield, Benjamin, Shroeder, Laura, Bishop, Henry, de Almeida, Marcos, Mathison, Blaine, Eberhard, Mark

Source: Clinical Infectious Diseases, 2016 Mar . 62(6), 778-783.

Access URL: https://www.jstor.org/stable/26370659