Delivery of gene editing therapeutics

Authors: Kevadiya, Bhavesh D., Islam, Farhana, Deol, Pallavi, Zaman, Lubaba A., Mosselhy, Dina A., Ashaduzzaman, Md, Bajwa, Neha, Routhu, Nanda Kishore, Singh, Preet Amol, Dawre, Shilpa, Vora, Lalitkumar K., Nahid, Sumaiya, Mathur, Deepali, Nayan, Mohammad Ullah, Baldi, Ashish, Kothari, Ramesh, Patel, Tapan A., Madan, Jitender, Gounani, Zahra, Bariwal, Jitender, Hettie, Kenneth S., Gendelman, Howard E.

Source: In Nanomedicine: Nanotechnology, Biology, and Medicine November 2023 54

Multifaceted roles of plant derived small molecule inhibitors on replication cycle of SARS-CoV-2

Authors: Uma Reddy, B., Routhu, Nanda Kishore, Kumar, Anuj

Source: In Microbial Pathogenesis July 2022 168

Podophyllum hexandrum and its active constituents: Novel radioprotectants

Authors: Anand, Uttpal, Biswas, Protha, Kumar, Vinay, Ray, Durga, Ray, Puja, Loake, Verity I.P., Kandimalla, Ramesh, Chaudhary, Anupama, Singh, Birbal, Routhu, Nanda Kishore, Chen, Zhe-Sheng, Proćków, Jarosław, Dey, Abhijit

Source: In Biomedicine & Pharmacotherapy February 2022 146

A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs

Authors: Routhu, Nanda Kishore, Cheedarla, Narayanaiah, Gangadhara, Sailaja, Bollimpelli, Venkata Satish, Boddapati, Arun K., Shiferaw, Ayalnesh, Rahman, Sheikh Abdul, Sahoo, Anusmita, Edara, Venkata Viswanadh, Lai, Lilin, Floyd, Katharine, Wang, Shelly, Fischinger, Stephanie, Atyeo, Caroline, Shin, Sally A., Gumber, Sanjeev, Kirejczyk, Shannon, Cohen, Joyce, Jean, Sherrie M., Wood, Jennifer S., Connor-Stroud, Fawn, Stammen, Rachelle L., Upadhyay, Amit A., Pellegrini, Kathryn, Montefiori, David, Shi, Pei-Yong, Menachery, Vineet D., Alter, Galit, Vanderford, Thomas H., Bosinger, Steven E., Suthar, Mehul S., Amara, Rama Rao

Source: In Immunity 9 March 2021 54(3):542-556

Polymeric Prodrugs Targeting Polyamine Metabolism Inhibit Zika Virus Replication

Authors: Routhu, Nanda Kishore, Xie, Ying, Dunworth, Matthew, Casero, Robert A., Oupicky, David, Byrareddy, Siddappa N.

Source: Molecular pharmaceutics. 15(9):4284-4295

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN617284205&indx=1&recIds=ETOCRN617284205

Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in nonhuman primates.

Authors: Routhu, Nanda Kishore, Stampfer, Samuel David, Lai, Lilin, Akhtar, Akil, Tong, Xin, Yuan, Dansu, Chicz, Taras M., McNamara, Ryan P., Jakkala, Kishor, Davis-Gardner, Meredith E., St Pierre, E. Lovisa, Smith, Brandon, Green, Kristyn Moore, Golden, Nadia, Picou, Breanna, Jean, Sherrie M., Wood, Jennifer, Cohen, Joyce, Moore, Ian N., Patel, Nita

Source: Science Immunology; 2023, Vol. 8 Issue 88, p1-15, 15p

Subject Terms: BOOSTER vaccines, SARS-CoV-2 Omicron variant, COVID-19 vaccines, BONE marrow cells, IMMUNOLOGIC memory

Company/Entity: NOVAVAX Inc.

A modified vaccinia Ankara vaccine expressing spike and nucleocapsid protects rhesus macaques against SARS-CoV-2 Delta infection.

Authors: Routhu, Nanda Kishore, Gangadhara, Sailaja, Lai, Lilin, Davis-Gardner, Meredith E., Floyd, Katharine, Shiferaw, Ayalnesh, Bartsch, Yannic C., Fischinger, Stephanie, Khoury, Georges, Rahman, Sheikh Abdul, Stampfer, Samuel David, Schäfer, Alexandra, Jean, Sherrie M., Wallace, Chelsea, Stammen, Rachelle L., Wood, Jennifer, Joyce, Cohen, Nagy, Tamas, Parsons, Matthew S., Gralinski, Lisa

Source: Science Immunology; 2022, Vol. 7 Issue 72, p1-16, 16p

SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung.

Authors: Routhu, Nanda Kishore, Cheedarla, Narayanaiah, Bollimpelli, Venkata Satish, Gangadhara, Sailaja, Edara, Venkata Viswanadh, Lai, Lilin, Sahoo, Anusmita, Shiferaw, Ayalnesh, Styles, Tiffany M., Floyd, Katharine, Fischinger, Stephanie, Atyeo, Caroline, Shin, Sally A., Gumber, Sanjeev, Kirejczyk, Shannon, Dinnon III, Kenneth H., Shi, Pei-Yong, Menachery, Vineet D., Tomai, Mark, Fox, Christopher B.

Source: Nature Communications; 6/11/2021, Vol. 12 Issue 1, p1-15, 15p

Subject Terms: SARS-CoV-2, PRIMATE diseases, ANTIBODY titer, RHESUS monkeys, PATHOLOGY, VIRAL antibodies

This result is not displayed to guests.
Login for full access.

Glycosylation of Zika Virus is Important in Host–Virus Interaction and Pathogenic Potential.

Authors: Routhu, Nanda Kishore¹ (AUTHOR) nanda.kishore.routhu@emory.edu, Lehoux, Sylvain D.^2,3 (AUTHOR) erouse@bidmc.harvard.edu, Rouse, Emily A.³ (AUTHOR), Bidokhti, Mehdi R. M.¹ (AUTHOR) mehdi.bidokhti@unmc.edu, Giron, Leila B.⁴ (AUTHOR) lgiron@wistar.org, Anzurez, Alitzel⁴ (AUTHOR) aanzurez@Wistar.org, Reid, St Patrick⁵ (AUTHOR) patrick.reid@unmc.edu, Abdel-Mohsen, Mohamed⁴ (AUTHOR) mmohsen@wistar.org, Cummings, Richard D.² (AUTHOR) rcummin1@bidmc.harvard.edu, Byrareddy, Siddappa N.^1,6,7 (AUTHOR) sid.byrareddy@unmc.edu

Source: International Journal of Molecular Sciences. Oct2019, Vol. 20 Issue 20, p5206. 1p.

Subject Terms: *ZIKA virus, *CELL receptors, *LECTINS, *GLYCOSYLATION, *GLYCANS, *CELL membranes, *HOST-virus relationships, *NEUROLOGICAL disorders

Retinoic Acid Improves the Recovery of Replication-Competent Virus from Latent SIV Infected Cells.

Authors: Olwenyi, Omalla A., Acharya, Arpan, Routhu, Nanda Kishore, Pierzchalski, Keely, Jones, Jace W., Kane, Maureen A., Sidell, Neil, Mohan, Mahesh, Byrareddy, Siddappa N.

Source: Cells (2073-4409); Sep2020, Vol. 9 Issue 9, p2076, 1p

Subject Terms: SIMIAN immunodeficiency virus, VIRUS isolation, TRETINOIN, BLOOD cells, T cells, RHESUS monkeys, RESERVOIR sedimentation

This result is not displayed to guests.
Login for full access.