Improvement in static and dynamic projections of drug-drug interactions caused by cytochrome P4503A time-dependent inhibitors through in vitro allosteric modulation by progesterone

Authors: Hegde, Pooja ^∗, Rodriguez, Brianna, Bell, Alec, Hall, Stephen D., Rougée, Luc R.A.

Source: In Drug Metabolism and Disposition February 2025 53(2)

Heterotropic allosteric modulation of CYP3A4 in vitro by progesterone: Evidence for improvement in prediction of time-dependent inhibition for macrolides

Authors: Rougée, Luc R.A. ^∗, Hegde, Pooja V., Shin, Kaitlin, Abraham, Trent L., Bell, Alec, Hall, Stephen D.

Source: In Drug Metabolism and Disposition January 2025 53(1)

Impact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4

Authors: Rougée, Luc R.A. ^*, Bedwell, David W., Hansen, Kasi, Abraham, Trent L., Hall, Stephen D.

Source: In Drug Metabolism and Disposition October 2023 51(10):1372-1380

The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2C9 and CYP3A4 Substrates

Authors: Rougée, Luc R.A. ^*, Mohutsky, Michael A., Bedwell, David W., Ruterbories, Kenneth J., Hall, Stephen D.

Source: In Drug Metabolism and Disposition September 2017 45(9):1008-1018

Difference in the Pharmacokinetics and Hepatic Metabolism of Antidiabetic Drugs in Zucker Diabetic Fatty and Sprague-Dawley Rats

Authors: Zhou, Xin ^*, Rougée, Luc R.A., Bedwell, David W., Cramer, Jeff W., Mohutsky, Michael A., Calvert, Nathan A., Moulton, Richard D., Cassidy, Kenneth C., Yumibe, Nathan P., Adams, Lisa A., Ruterbories, Kenneth J.

Source: In Drug Metabolism and Disposition August 2016 44(8):1184-1192

The Ontogeny and Population Variability of Human Hepatic NADPH Dehydrogenase Quinone Oxido-Reductase 1 (NQO1)

Authors: Rougée, Luc R.A, Riches, Zoe, Berman, Jacob M, Collier, Abby C ^*

Source: In Drug Metabolism and Disposition July 2016 44(7):967-974

Molecular reproductive characteristics of the reef coral Pocillopora damicornis

Authors: Rougée, Luc R.A., Richmond, Robert H., Collier, Abby C.

Source: In Comparative Biochemistry and Physiology, Part A November 2015 189:38-44

UDP-Glucuronosyltransferase 1a Enzymes Are Present and Active in the Mouse Blastocyst

Authors: Collier, Abby C. ^*, Yamauchi, Yasuhiro, Sato, Brittany L.M., Rougée, Luc R.A., Ward, Monika A.

Source: In Drug Metabolism and Disposition November 2014 42(11):1921-1925

Heterotropic allosteric modulation of CYP3A4 in vitro by progesterone: evidence for improvement in prediction of time-dependent inhibition for macrolides

Authors: Rougée, Luc R.A., Hegde, Pooja V., Shin, Kaitlin, Abraham, Trent L., Bell, Alec, Hall, Stephen D.

Source: Drug Metabolism and Disposition; 20240101, Issue: Preprints