Molecular MR Imaging of Renal Fibrogenesis in Mice

Authors: Chen, Yin-Ching, Waghorn, Philip A., Rosales, Ivy A., Arora, Gunisha, Erstad, Derek J., Rotile, Nicholas J., Jones, Chloe M., Ferreira, Diego S., Wei, Lan, Martinez, Robert V. P.

Source: Journal of the American Society of Nephrology. 34(7):1159-1166

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632886297&indx=1&recIds=ETOCRN632886297

Dual Hydrazine-Equipped Turn-On Manganese-Based Probes for Magnetic Resonance Imaging of Liver Fibrogenesis

Authors: Ning, Yingying, Zhou, Iris Yuwen, Rotile, Nicholas J., Pantazopoulos, Pamela, Wang, Huan, Barrett, Stephen Cole, Sojoodi, Mozhdeh, Tanabe, Kenneth K., Caravan, Peter

Source: Journal of the American Chemical Society. 144(36):16553-16558

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630178507&indx=1&recIds=ETOCRN630178507

Molecular Magnetic Resonance Imaging of Liver Fibrosis and Fibrogenesis Is Not Altered by Inflammation

Authors: dos Santos Ferreira, Diego, Arora, Gunisha, Gieseck, Richard L., Rotile, Nicholas J., Waghorn, Philip A., Tanabe, Kenneth K., Wynn, Thomas A., Caravan, Peter, Fuchs, Bryan C.

Source: Investigative radiology. 56(4):244-251

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182515705.0x000001&indx=1&recIds=ETOCvdc_100182515705.0x000001

Positron Emission Tomography–Magnetic Resonance Imaging Pharmacokinetics, In Vivo Biodistribution, and Whole-Body Elimination of Mn-PyC3A

Authors: Zhou, Iris Yuwen, Ramsay, Ian A., Ay, Ilknur, Pantazopoulos, Pamela, Rotile, Nicholas J., Wong, Alison, Caravan, Peter, Gale, Eric M.

Source: Investigative radiology. 56(4):261-270

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182515726.0x000001&indx=1&recIds=ETOCvdc_100182515726.0x000001

Development of a fibrin-targeted theranostic for gastric cancer.

Authors: Esfahani, Shadi A., Ma, Li, Krishna, Shriya, Ma, Hua, Raheem, Shvan J., Shuvaev, Sergey, Rotile, Nicholas J., Weigand-Whittier, Jonah, Boice, Avery T., Borges, Nicholas, Treaba, Constantina A., Deffler, Caitlin, Diyabalanage, Himashinie, Humblet, Valerie, Sosnovik, David E., Mahmood, Umar, Heidari, Pedram, Shih, Angela, Catana, Ciprian, Strickland, Matthew R.

Source: Science Translational Medicine; 12/11/2024, Vol. 16 Issue 777, p1-17, 17p

Subject Terms: POSITRON emission tomography, ESOPHAGOGASTRIC junction, CANCER patients, MAGNETIC resonance imaging, TUMOR growth

Yttrium‐86 Is a Positron Emitting Surrogate of Gadolinium for Noninvasive Quantification of Whole‐Body Distribution of Gadolinium‐Based Contrast Agents

Authors: Le Fur, Mariane, Rotile, Nicholas J., Correcher, Carlos, Clavijo Jordan, Veronica, Ross, Alana W., Catana, Ciprian, Caravan, Peter

Source: Angewandte Chemie. 132(4):1490-1494

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110414005.0x000001&indx=1&recIds=ETOCvdc_100110414005.0x000001

Revisiting dithiadiaza macrocyclic chelators for copper-64 PET imagingElectronic supplementary information (ESI) available. CCDC 2003358, 2003359 and 2003361. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/d0dt02787a

Authors: Shuvaev, Sergey, Suturina, Elizaveta A., Rotile, Nicholas J., Astashkin, Andrei, Ziegler, Christopher J., Ross, Alana W., Walker, Tia L., Caravan, Peter, Taschner, Ian S.

Source: Dalton transactions. 49(40):14088-14098

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110405312.0x000001&indx=1&recIds=ETOCvdc_100110405312.0x000001

Advanced MRI of Liver Fibrosis and Treatment Response in a Rat Model of Nonalcoholic Steatohepatitis

Authors: Zhou, Iris Y., Jordan, Veronica Clavijo, Rotile, Nicholas J., Akam, Eman, Krishnan, Smitha, Arora, Gunisha, Krishnan, Hema, Slattery, Hannah, Warner, Noah, Mercaldo, Nathaniel

Source: Radiology. 296(1):67-75

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624146108&indx=1&recIds=ETOCRN624146108

^6^8Ga-NODAGA-Indole: An Allysine-Reactive Positron Emission Tomography Probe for Molecular Imaging of Pulmonary Fibrogenesis

Authors: Wahsner, Jessica, Désogère, Pauline, Abston, Eric, Graham-O Regan, Katherine A., Wang, Junfeng, Rotile, Nicholas J., Schirmer, Markus D., Dos Santos Ferreira, Diêgo, Sui, Jingyi, Fuchs, Bryan C.

Source: Journal of the American Chemical Society. 141(14):5593-5596

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN619717349&indx=1&recIds=ETOCRN619717349

Improving the reactivity of hydrazine-bearing MRI probes for in vivo imaging of lung fibrogenesisElectronic supplementary information (ESI) available. See DOI: 10.1039/c9sc04821a

Authors: Akam, Eman A., Abston, Eric, Rotile, Nicholas J., Slattery, Hannah R., Zhou, Iris Y., Lanuti, Michael, Caravan, Peter

Source: Chemical science. 11(1):224-231

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192837568.0x000001&indx=1&recIds=ETOCvdc_100192837568.0x000001

Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies.

Authors: Esfahani, Shadi A., Hua Ma, Krishna, Shriya, Shuvaev, Sergey, Sabbagh, Mark, Deffler, Caitlin, Rotile, Nicholas, Weigand-Whittier, Jonah, Zhou, Iris Y., Catana, Ciprian, Catalano, Onofrio A., Ting, David T., Heidari, Pedram, Abston, Eric, Lanuti, Michael, Boland, Genevieve M., Pathak, Priyanka, Roberts, Hannah, Tanabe, Kenneth K., Qadan, Motaz

Source: Theranostics; 2024, Vol. 14 Issue 15, p5745-5761, 17p

Simultaneous Positron Emission Tomography and Molecular Magnetic Resonance Imaging of Cardiopulmonary Fibrosis in a Mouse Model of Left Ventricular Dysfunction.

Authors: Moon, Brianna F., Zhou, Iris Y., Yingying Ning, Chen, Yin-Ching I., Le Fur, Mariane, Shuvaev, Sergey, Akam, Eman A., Hua Ma, Solsona, Cesar Molinos, Weigand Whittier, Jonah, Rotile, Nicholas, Hariri, Lida P., Drummond, Matthew, Boice, Avery T., Zygmont, Samantha E., Sharma, Yamini, Warburton, Rod R., Martin, Gregory L., Blanton, Robert M., Fanburg, Barry L.

Source: Journal of the American Heart Association; 7/16/2024, Vol. 13 Issue 14, p1-13, 13p

Non-invasive imaging method demonstrates anti-fibrotic efficacy of a dual integrin alpha-v/beta-6 and alpha-v/beta-1 inhibitor in a rat model of biliary fibrosis

Authors: Schaub, Johanna, Ning, Yingying, Zhou, Iris Y., Rotile, Nicholas, Boice, Avery, Lau, Jessie, Caravan, Peter, Turner, Scott

Source: Journal of hepatology. 78(S1):S413-S414

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195507431.0x000001&indx=1&recIds=ETOCvdc_100195507431.0x000001

Molecular magnetic resonance imaging accurately measures the antifibrotic effect of EDP‐305, a novel farnesoid X receptor agonist

Authors: Erstad, Derek J., Farrar, Christian T., Ghoshal, Sarani, Masia, Ricard, Ferreira, Diego S., Chen, Yin‐Ching Iris, Choi, Ji‐Kyung, Wei, Lan, Waghorn, Phillip A., Rotile, Nicholas J., Tu, Chuantao, Graham‐O'Regan, Katherine A., Sojoodi, Mozhdeh, Li, Shen, Li, Yang, Wang, Guogiang, Corey, Kathleen E., Or, Yat Sun, Jiang, Lijuan, Tanabe, Kenneth K., Caravan, Peter, Fuchs, Bryan C.

Source: Hepatology research. 2(7):821-835

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083713155.0x000001&indx=1&recIds=ETOCvdc_100083713155.0x000001

Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications

Authors: Dai, Lixiong, Jones, Chloe, Chan, Wesley, Pham, Tiffany, Ling, Xiaoxi, Gale, Eric, Rotile, Nicholas, Tai, William, Anderson, Carolyn, Caravan, Peter, Law, Ga-Lai

Source: Nature communications. 9(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125086380.0x000001&indx=1&recIds=ETOCvdc_100125086380.0x000001

Molecular Magnetic Resonance Imaging of Lung Fibrogenesis with an Oxyamine‐Based Probe

Authors: Waghorn, Philip A., Jones, Chloe M., Rotile, Nicholas J., Koerner, Steffi K., Ferreira, Diego S., Chen, Howard H., Probst, Clemens K., Tager, Andrew M., Caravan, Peter

Source: Angewandte Chemie international edition. 56(33):9825-9828

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083147270.0x000001&indx=1&recIds=ETOCvdc_100083147270.0x000001

Optimization of a Collagen-Targeted PET Probe for Molecular Imaging of Pulmonary Fibrosis

Authors: Désogère, Pauline, Tapias, Luis F., Rietz, Tyson A., Rotile, Nicholas, Blasi, Francesco, Day, Helen, Elliott, Justin, Fuchs, Bryan C., Lanuti, Michael, Caravan, Peter

Source: Journal of nuclear medicine. 58(12):1991-1996

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN614127671&indx=1&recIds=ETOCRN614127671

Detection of Pulmonary Fibrosis with a Collagen-Mimetic Peptide.

Authors: Borgula, Isabella M., Shuvaev, Sergey, Abston, Eric, Rotile, Nicholas J., Weigand-Whittier, Jonah, Zhou, Iris Y., Caravan, Peter, Raines, Ronald T.

Source: ACS Sensors; 11/24/2023, Vol. 8 Issue 11, p4008-4013, 6p

Multisite Thrombus Imaging and Fibrin Content Estimation With a Single Whole-Body PET Scan in Rats

Authors: Blasi, Francesco, Oliveira, Bruno L., Rietz, Tyson A., Rotile, Nicholas J., Naha, Pratap C., Cormode, David P., Izquierdo-Garcia, David, Catana, Ciprian, Caravan, Peter

Source: Arteriosclerosis, thrombosis, and vascular biology. 35(10):2114-2121

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100037046584.0x000001&indx=1&recIds=ETOCvdc_100037046584.0x000001

Radiation Dosimetry of the Fibrin-Binding Probe ^6^4Cu-FBP8 and Its Feasibility for PET Imaging of Deep Vein Thrombosis and Pulmonary Embolism in Rats

Authors: Blasi, Francesco, Oliveira, Bruno L., Rietz, Tyson A., Rotile, Nicholas J., Day, Helen, Naha, Pratap C., Cormode, David P., Izquierdo-Garcia, David, Catana, Ciprian, Caravan, Peter

Source: Journal of nuclear medicine. 56(7):1088-1093

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN601880554&indx=1&recIds=ETOCRN601880554