Context-restricted PD-(L)1 checkpoint agonism by CTLA4-Ig therapies inhibits T cell activity

Authors: Ethan P. Oxley, Nadia J. Kershaw, Cynthia Louis, Katharine J. Goodall, Maximilian M. Garwood, Skye Min Jee Ho, Veronica T.F. Voo, Hae-Young Park, Josephine Iaria, Lilian L.L. Wong, Ariel G. Lebenbaum, Stephanie Wiranata, Ee Shan Pang, Emily S.J. Edwards, Damian B. D’Silva, Jacinta Hansen, Menno C. van Zelm, Meredith O’Keeffe, P. Mark Hogarth, Nicole M. Haynes, Nicholas D. Huntington, Ian P. Wicks, Ross A. Dickins

Source: Cell Reports, Vol 43, Iss 10, Pp 114834- (2024)

Subject Terms: CP: Immunology, Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S2211124724011859; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/6c8609b2d6c447c2abb2c3c69d1e33ba

Acute myeloid leukemia maturation lineage influences residual disease and relapse following differentiation therapy

Authors: Steven Ngo, Ethan P. Oxley, Margherita Ghisi, Maximilian M. Garwood, Mark D. McKenzie, Helen L. Mitchell, Peter Kanellakis, Olivia Susanto, Michael J. Hickey, Andrew C. Perkins, Benjamin T. Kile, Ross A. Dickins

Source: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/5f04ec10aa484e7aa4589412ec95bdf7

Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia

Authors: Quentin Van Thillo, Jolien De Bie, Janith A. Seneviratne, Sofie Demeyer, Sofia Omari, Anushree Balachandran, Vicki Zhai, Wai L. Tam, Bram Sweron, Ellen Geerdens, Olga Gielen, Sarah Provost, Heidi Segers, Nancy Boeckx, Glenn M. Marshall, Belamy B. Cheung, Kiyotaka Isobe, Itaru Kato, Junko Takita, Timothy G. Amos, Ira W. Deveson, Hannah McCalmont, Richard B. Lock, Ethan P. Oxley, Maximilian M. Garwood, Ross A. Dickins, Anne Uyttebroeck, Daniel R. Carter, Jan Cools, Charles E. de Bock

Source: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

Subject Terms: Science

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Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/097bfb27edca4477bb37a09172ff1f71

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene

Authors: Marcus Lefebure, Richard W. Tothill, Elizabeth Kruse, Edwin D. Hawkins, Jake Shortt, Geoffrey M. Matthews, Gareth P. Gregory, Benjamin P. Martin, Madison J. Kelly, Izabela Todorovski, Maria A. Doyle, Richard Lupat, Jason Li, Jan Schroeder, Meaghan Wall, Stuart Craig, Gretchen Poortinga, Don Cameron, Megan Bywater, Lev Kats, Micah D. Gearhart, Vivian J. Bardwell, Ross A. Dickins, Ross D. Hannan, Anthony T. Papenfuss, Ricky W. Johnstone

Source: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0c3aa501a43e4f4f934206118b33d4f2

Combined Targeting of JAK2 and Bcl-2/Bcl-xL to Cure Mutant JAK2-Driven Malignancies and Overcome Acquired Resistance to JAK2 Inhibitors

Authors: Michaela Waibel, Vanessa S. Solomon, Deborah A. Knight, Rachael A. Ralli, Sang-Kyu Kim, Kellie-Marie Banks, Eva Vidacs, Clemence Virely, Keith C.S. Sia, Lauryn S. Bracken, Racquel Collins-Underwood, Christina Drenberg, Laura B. Ramsey, Sara C. Meyer, Megumi Takiguchi, Ross A. Dickins, Ross Levine, Jacques Ghysdael, Mark A. Dawson, Richard B. Lock, Charles G. Mullighan, Ricky W. Johnstone

Source: Cell Reports, Vol 5, Iss 4, Pp 1047-1059 (2013)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124713006372; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/038b13b134c84948ae45ebf210800b23

edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens [v2; ref status: indexed, http://f1000r.es/4kw]

Authors: Zhiyin Dai, Julie M. Sheridan, Linden J. Gearing, Darcy L. Moore, Shian Su, Sam Wormald, Stephen Wilcox, Liam O'Connor, Ross A. Dickins, Marnie E. Blewitt, Matthew E. Ritchie

Source: F1000Research, Vol 3 (2014)

Subject Terms: Bioinformatics, Medicine, Science

File Description: electronic resource

Relation: http://f1000research.com/articles/3-95/v2; https://doaj.org/toc/2046-1402

Access URL: https://doaj.org/article/af57121b5c294c7eace7aaa79327324c

shRNA-seq data analysis with edgeR [v1; ref status: indexed, http://f1000r.es/38s]

Authors: Zhiyin Dai, Julie M. Sheridan, Linden J. Gearing, Darcy L. Moore, Shian Su, Ross A. Dickins, Marnie E. Blewitt, Matthew E. Ritchie

Source: F1000Research, Vol 3 (2014)

Subject Terms: Bioinformatics, Medicine, Science

File Description: electronic resource

Relation: http://f1000research.com/articles/3-95/v1; https://doaj.org/toc/2046-1402

Access URL: https://doaj.org/article/4533c408378049aa96ae320cc3b3c3bf

Humanizing the Protease-Activated Receptor (PAR) Expression Profile in Mouse Platelets by Knocking PAR1 into the Par3 Locus Reveals PAR1 Expression Is Not Tolerated in Mouse Platelets.

Authors: Shauna L French, Antonia C Paramitha, Mitchell J Moon, Ross A Dickins, Justin R Hamilton

Source: PLoS ONE, Vol 11, Iss 10, p e0165565 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5082849?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/4e233ad6941544a2b318049907a68d2f

Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.

Authors: Megumi Takiguchi, Lukas E Dow, Julia E Prier, Catherine L Carmichael, Benjamin T Kile, Stephen J Turner, Scott W Lowe, David C S Huang, Ross A Dickins

Source: PLoS ONE, Vol 8, Iss 1, p e54009 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3543435?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/a4d0ee6ef1d84da08f49721cc3307f63