Safety and efficacy of a fitusiran antithrombin-based dose regimen in people with hemophilia A or B: the ATLAS-OLE study

Authors: Khoo, Teh-Liane, Dunkley, Scott, P'ng, Stephanie, Pepperell, Dominic, Lam, Stephanie, Steinepreis, Elizabeth, Malherbe, Jacques, Kendrick, Tulene, Lombard, Marcus, Tran, Huyen, Zhao, Jessie, Stevens, Hannah, Dix, Caroline, McFadyen, James, St-Louis, Jean, Kassis, Jeannine, Rivard, Georges, Sun, Jing, Li, Xiaofang, Li, Huiping, Ye, Jieyu, Zhou, Xuan, Du, Dong, Wang, Xuefeng, Dai, Jing, Ding, Quilan, Wu, Wenman, Lu, Yiyi, Wu, Runhui, Liu, Guoqing, Yao, Wanru, Wang, Yan, Wei, Yunyun, Xu, Weiqun, Du, Yu, Xu, Liyao, Wang, Di, Liao, Chan, Zhang, Hongwei, Yu, Ziqiang, Tian, Hong, Wang, Haibo, Yin, Jie, Zhu, Tienan, Cai, Huacong, Xiao, Juan, Wang, Shujie, Liu, Shufen, Shen, Kaini, Chen, Yun, Chang, Yali, Sang, Tan, Zhao, Jun, Zhou, Yawei, Zhai, Liya, Qiu, Xiadong, He, Yulei, Li, Hui, Xia, Yi, Zhou, Min, Gao, Feng, Feng, Shipin, Luo, Xiaoli, Li, Dan, Cui, Zhongguang, Zhao, Chunzhu, Xu, Hong, Sun, Lingjie, Shi, Xue, Zeng, Xiaojing, Qi, Lu, Cao, Shuyun, Zhou, Zeping, Zhang, Fuhou, Yin, Lingmei, Mu, Hongli, Bi, Hui, Li, Zhengchao, Miu, Yaping, Xi, Yaming, Jia, Mingfeng, Zhao, Long, Zhao, Xielan, Li, Yaochun, Peng, Jie, Chang, Chia-Yau, Liu, Yen-Lin, Shen, Ming-Ching, Huang, Cheng-Wei, Wang, Shih-Chung, Lin, Hsuan-Yu, Lin, Ching-Yeh, Chou, Sheng-Chieh, Chuang, Ming-Kai, Hsu, Szu-Chun, Wang, Jiaan-Der, Shih, Ming-Yang, Hsiao, Liang-Tsai, Hung, Giun-Yi, Yen, Hsiu-Ju, Ko, Po-Shen, Chang, Hung, Chen, Shih-Hsaing, Weng, Te-Fu, Chao, Yu-Hua, Zeng, Sherig-Wei, Kampmann, Peter, Funding, Eva, Dargaud, Yesim, Negrier, Claude, Desag, Stéphanie, Frenzel, Laurent, Fouquet, Guillemette, Bally, Cécile, Klamroth, Robert, Orlovic, Ana-Marija, Pfrepper, Christian, Metze, Michael, Chakaroun, Rima, Weise, Maria, Nemes, László, Ronatas, Agnes, Ross, Cecil, Anandram, Seetharam, Bharadwaj, Vandana, Salvi, Sonali, Lohande, Sunil, Srivastava, Alok, Abraham, Aby, Aboobacker, Fouzia, Verma, Shailendra, Datta, Gaurav, Rangarajan, Savita, Bansal, Shweta, Apte, Shashikant, Subramanian, Kannan, Nolan, Beatrice, Ahmed, Saad, O’Connell, Niamh, O’Donnell, James, Ryan, Kevin, Lavin, Michelle, Kenet, Gili, Cohen, Omri, Misgav, Mudi, Barg, Assaf, Mendelovich, Sarina Levy, Peyvandi, Flora, Gualtierotti, Roberta, Zanon, Ezio, Spiezia, Luca, Simion, Chiara, Matsushita, Tadashi, Okamoto, Shuichi, Suzuki, Nobuaki, Kanematsu, Takeshi, Suzuki, Naruko, Kawaguchi, Yuka, Higasa, Satoshi, Tokugawa, Tazuko, Sawada, Akihiro, Shirayama, Rie, Kawamura, Masaru, Asai, Hiroshi, Oshida, Koichi, Sato, Tetsuji, Ito, Takuma, Koh, Katsuyoshi, Mizushima, Yoshitaka, Ishikawa, Takahiro, Kubota, Hirohito, Kaneko, Ryota, Irikura, Tomoya, Honda, Mamoru, Taira, Katsuaki, Arakawa, Yuki, Mori, Makiko, Fukoka, Kohei, Oshima, Koichi, Mitani, Yuichi, Ogawa, Yoshiaki, Ando, Kiyoshi, Suzuki, Rikio, Hara, Ryujiro, Aoyama, Yasuyuki, Toyosaki, Masako, Ogiya, Daisuke, Machida, Shinichiro, Kawada, Hiroshi, Shirasugi, Yukari, Onizuka, Makoto, Omachi, Ken, Amano, Kagehiro, Yamaguchi, Tomoko, Kinai, Ei, Hagiwara, Takeshi, Yotsumoto, Mihoko, Sekiya, Ryoko, Bingo, Masato, Chikasawa, Yushi, Ichiki, Akito, Kamikubo, Yoshiko, Miyashita, Ryui, Muramatsu, Takashi, Shin, Ho-Jin, Kim, DoYoung, You, Chur-Woo, Kim, Ju Young, Hahn, Seung Min, Lyu, Chuhl Joo, Han, Jung Woo, Park, Young Shil, Cho, Ja Hyang, Shariq, Azizan, Lim, Soo Min, Wong, Lily, Chang Choo, Heng, Wilfred, Gilbert, Ahmad Zakhi, Mohd Tarmizi, Lim, Yin Man, Raghunathan, Khaiteri, Sathar, Jameela, Nasution, Syazarin Fidhora, Yap, Yee Yee, Selvaratnam, Veena, Malan, Daniel, Punt, Zelda Erika, Antmen, Ali Bulent, Sasmaz, Ilgen, Aygunes, Utku, Kavakli, Kaan, Karadas, Nihal, Karapinar, Deniz, Kupesiz, Alphan, Erkan, Mine, Tayfun, Kupesiz Funda, Guler, Elif, Zulfikar, Bulent, Koc, Basak, Okan, Vahap, Haydaroglu, Sahin Handan, Albayrak, Canan, Kartal, Ibrahim, Yilmaz, Ebru, Karakukcu, Musa, Unal, Ekrem, Ozcan, Alper, Sahin, Fahri, Tuzun, Betul, Saydam, Guray, Averianov, Ievgenii, Kovtunenko, Oksana, Stasyshyn, Oleksandra, Semerak, Maksym, Tushnytskyy, Orest, Vilchevska, Kateryna, Bakhchyvandzhy, Iryna, Romanyuk, Nataliya, Nikulin, Stanislav, Kobets, Alina, Alamelu MRCPCH, Jayanthi, Babiker, Samah, Bagot, Catherine, Rodgers, James Tyan, Boggio, Lisa, Simpson, Mindy, Cockrell, Erin, DeBerry, Candance, Obzut, Dana, Fargo, John, Hord, Jeffrey, Savelli, Stephanie, Lasky, Joseph, Buitrago, Jennifer, Alhushki, Waseem, Gauger, Cynthia, Klawinski, Darren, Sandler, Eric, Bradfield, Scott, Pitel, Paul, Joyce, Michael, Katzenstein, Howard, Bansal, Manisha, Bechtel, Allison, Knoll, Christine, Gomez, Esteban, White, Shanna, Shah, Sanjay, Gendreau, Joanna, Wagner, Lori, Quarmyne, Maa-Ohui, Bornikova, Larissa, Cleary CNP, Colleen, Hodges, Pamela G., Mossali, Alexandra, Rosovsky, Rachel, Turbini, Victoria, Wood, Valerie, Al-Samkari, Hanny, Pipe, Steven, Weyand, Angela, Shavit, Jordan, Soni, Amit, Nugent, Diane, Hwang, Nina, Salinas, Vanessa, Young, Guy, Hofstra, Tom, Donkin, Jennifer, Keegan, Jacquelyn, Sibgha, Zaheer, Leung, Wendy, Jaffray, Julie, Pipe, Steven W. ⁷, Menapace, Laurel A. ¹⁷, Zhang, Chuanwu ¹⁸, Shen, Yuqian ¹⁹, Puurunen, Marja ¹⁷, Demissie, Marek ¹⁷

Source: In Blood February 2025

Management of pregnancy and delivery in congenital fibrinogen disorders: communication from the ISTH SSC Subcommittee on Factor XIII and Fibrinogen

Authors: Casini, Alessandro, Abdul Kadir, Rezan, Abdelwahab, Magy, Manco-Johnson, Marilyn J., Raut, Sanj, Ross, Cecil, de Moerloose, Philippe, Santoro, Cristina, Acharya, Suchitra

Source: In Journal of Thrombosis and Haemostasis May 2024 22(5):1516-1521

High-throughput and label-free screening of red blood cell stiffness: A study of sickle cell disease

Authors: Kaushik, Saurabh ^a, Mishra, Arkabrata ^a, Ross, Roshan ^b, Srivastava, Sweta ^b, Ross, Cecil R. ^b, Soni, Gautam V. ^{a, ⁎}

Source: In Biosensors and Bioelectronics: X August 2025 24

Efficacy and safety of fitusiran prophylaxis in people with haemophilia A or haemophilia B with inhibitors (ATLAS-INH): a multicentre, open-label, randomised phase 3 trial

Authors: Young, Guy, Srivastava, Alok, Kavakli, Kaan, Ross, Cecil, Sathar, Jameela, You, Chur-Woo, Tran, Huyen, Sun, Jing, Wu, Runhui, Poloskey, Stacey, Qiu, Zhiying, Kichou, Salim, Andersson, Shauna, Mei, Baisong, Rangarajan, Savita

Source: Lancet. 401(10386):1427-1437

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188834122.0x000001&indx=1&recIds=ETOCvdc_100188834122.0x000001

FUBP3 regulates chronic myeloid leukaemia progression through PRC2 complex regulated PAK1‐ERK signalling

Authors: Sharma, Mugdha, Anandram, Seetharam, Ross, Cecil, Srivastava, Sweta

Source: Journal of cellular and molecular medicine. 27(1):15-29

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182180524.0x000001&indx=1&recIds=ETOCvdc_100182180524.0x000001

Pharmacokinetics, efficacy and safety of a novel fibrinogen concentrate in pediatric patients with congenital afibrinogenemia

Authors: Khayat, Claudia Djambas, Navarro-Puerto, Jordi, Ross, Cecil Reuben, Subramanian, Kannan, Kalappanavar, Nijalingappa K., Rucker, Karen, Liang, Wei, Mondou, Elsa

Source: Blood coagulation and fibrinolysis. 34(1):61-69

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180320434.0x000001&indx=1&recIds=ETOCvdc_100180320434.0x000001

A bioinformatics pipeline for sequence to structure: A case study with a Cml patient undergoing treatment with imatinib

Authors: Chacko, Anita Rachel, Patil, Shankarrao, Upadhayay, Atul K., Nagrajan, Ashwat, Khatri, Rakesh, Arya, Deepak, Krishna, Sudhir, Sowdhamini, R., Ross, Cecil

Source: 2013 Biomedical Sciences and Engineering Conference (BSEC) Biomedical Sciences and Engineering Conference (BSEC), 2013. :1-4 May, 2013

Relation: 2013 Biomedical Sciences and Engineering Conference (BSEC)

Clinical phenotype, fibrinogen supplementation, and health-related quality of life in patients with afibrinogenemia

Authors: Casini, Alessandro ^{*, *}, von Mackensen, Sylvia ^*, Santoro, Cristina, Djambas Khayat, Claudia, Belhani, Meriem, Ross, Cecil, Dorgalaleh, Akbar, Naz, Arshi, Ünal, Ekrem, Abdelwahab, Magy, Lozeron, Elise Dupuis, Trillot, Nathalie, Susen, Sophie, Peyvandi, Flora, de Moerloose, Philippe

Source: In Blood 3 June 2021 137(22):3127-3136

Pharmacokinetics, surrogate efficacy and safety evaluations of a new human plasma-derived fibrinogen concentrate (FIB Grifols) in adult patients with congenital afibrinogenemia

Authors: Ross, Cecil Reuben, Subramanian, Sitalakshmi, Navarro-Puerto, Jordi, Subramanian, Kannan, Kalappanavar, Nijalingappa K., Khayat, Claudia Djambas, Acharya, Suchitra S., Peyvandi, Flora, Rucker, Karen, Liang, Wei, Vilardell, David, Trimm, Sabile, Ayguasanosa, Jaume

Source: In Thrombosis Research March 2021 199:110-118

Mortality in Haemophilia Patients in India: A National Cohort Study.

Authors: Shetty, Shrimati¹ (AUTHOR) shrimatishetty@gmail.com, Ross, Cecil² (AUTHOR), John, M. Joseph³ (AUTHOR), Kshirsagar, Shrinath¹ (AUTHOR), Kulkarni, Nimish¹ (AUTHOR), Pavitra, D. S.³ (AUTHOR), Sarwan, Diksha³ (AUTHOR), Misha, P. K.² (AUTHOR), Paul, Antony² (AUTHOR), More, Apurva¹ (AUTHOR), Kaunchale, Nazish¹ (AUTHOR), D'silva, Magdalene¹ (AUTHOR), Masurkar, Shrushti¹ (AUTHOR), Kharat, Shruti¹ (AUTHOR), Patil, Kranti¹ (AUTHOR), Patel, Shalaka⁴ (AUTHOR), Mehendale, Priti⁴ (AUTHOR), Sarvaiya, Prachi⁴ (AUTHOR), Rangarajan, Savita¹ (AUTHOR)

Source: Haemophilia. Jan2025, Vol. 31 Issue 1, p132-139. 8p.

Subject Terms: *MORTALITY, *HEMOPHILIA, *INTRACRANIAL hemorrhage, *THERAPEUTICS, *COHORT analysis, *LIFE expectancy, *COMORBIDITY

Geographic Terms: INDIA

Turoctocog alfa is safe for the treatment of Indian patients with hemophilia A: Guardian 10 trial results

Authors: John, M. Joseph, Chakrabarti, Prantar ^*, Apte, Shashikant, Bhattacharyya, Maitreyee, S., Chandrakala, Hansen, Trine, Kolla, Rohan, Ross, Cecil, Seth, Tulika, Siddharthan, Neeraj, Abraham, Aby

Source: In Research and Practice in Thrombosis and Haemostasis November 2020 4(8):1324-1330

Fibrinogen concentrate for treatment of bleeding and surgical prophylaxis in congenital fibrinogen deficiency patients

Authors: Lissitchkov, Toshko, Madan, Bella, Djambas Khayat, Claudia, Zozulya, Nadezhda, Ross, Cecil, Karimi, Mehran, Kavakli, Kaan, De Angulo, Guillermo R., Almomen, Abdulkareem, Subramanian, Kannan, D'Souza, Fulton, Viswabandya, Auro, Hoorfar, Hamid, Schwartz, Bruce A., Solomon, Cristina, Knaub, Sigurd, Peyvandi, Flora ^*

Source: In Journal of Thrombosis and Haemostasis April 2020 18(4):815-824

Effect of point mutation on structure–function correlation of hemoglobin variants, HbE and HbD Punjab

Authors: Narayanan, Sreekala, Mathew, Boby, Srinivasu, Bindu Y., Bhat, Vijay, Ross, Cecil, Mandal, Amit Kumar

Source: Amino acids. 52(6-7):893-904

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168092931.0x000001&indx=1&recIds=ETOCvdc_100168092931.0x000001

Microarray analysis reveals distinct immune signatures in BCR-ABL positive and negative myeloproliferative neoplasms.

Authors: Ross, Cecil¹, Sharma, Mugdha¹, Paul, John¹, Srivastava, Sweta² sweta.s@stjohns.in

Source: Indian Journal of Cancer. Jan-Mar2023, Vol. 60 Issue 1, p24-31. 8p.

Subject Terms: *MYELOPROLIFERATIVE neoplasms, *CHRONIC myeloid leukemia, *PHILADELPHIA chromosome, *MYELOFIBROSIS, *SRC gene, *GENE regulatory networks

RhoC regulates radioresistance via crosstalk of ROCK2 with the DNA repair machinery in cervical cancer

Authors: Pranatharthi, Annapurna, Thomas, Pavana, Udayashankar, Avinash, Bhavani, Chandra, Suresh, Srinag, Krishna, Sudhir, Thatte, Jayashree, Srikantia, Nirmala, Ross, Cecil, Srivastava, Sweta

Source: Journal of experimental & clinical cancer research. 38(1):1-24

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191691188.0x000001&indx=1&recIds=ETOCvdc_100191691188.0x000001

RhoC: a fascinating journey from a cytoskeletal organizer to a Cancer stem cell therapeutic target

Authors: Thomas, Pavana, Pranatharthi, Annapurna, Ross, Cecil, Srivastava, Sweta

Source: Journal of experimental & clinical cancer research. 38(1):1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189319485.0x000001&indx=1&recIds=ETOCvdc_100189319485.0x000001

Ally to adversary: mesenchymal stem cells and their transformation in leukaemia

Authors: Sharma, Mugdha, Ross, Cecil, Srivastava, Sweta

Source: Cancer cell international. 19(1):1-9

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188049241.0x000001&indx=1&recIds=ETOCvdc_100188049241.0x000001

Immunogenicity and safety of quadrivalent and 9-valent human papillomavirus vaccines in Indian clinical trial participants

Authors: Garland, Suzanne M., Anagani, Manjula, Bhatla, Neerja, Chatterjee, Sukanta, Lalwani, Sanjay, Ross, Cecil, Group, Thomas, Lin, Jianxin, Luxembourg, Alain, Walia, Anuj, Tu, Yingmei

Source: Human vaccines & immunotherapeutics. 18(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180431466.0x000001&indx=1&recIds=ETOCvdc_100180431466.0x000001

Safety and efficacy of intravenous immunoglobulin (Flebogamma® 10% DIF) in patients with immune thrombocytopenic purpura

Authors: Apte, Shashikant, Navarro-Puerto, Jordi, Damodar, Sharat, Ramanan, Vijay, John, Joseph, Kato, Giraldo, Ross, Cecil, Shah, Chirag, Torres, Marcela, Fu, Chieh-Lin 'Kathy', Rucker, Karen, Pinciaro, Paul, Barrera, Gladis, Aragonés, Maria Esperança, Ayguasanosa, Jaume

Source: Immunotherapy. 11(2):81-89

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188378299.0x000001&indx=1&recIds=ETOCvdc_100188378299.0x000001

Reduced Volume and Faster Infusion Rate of Activated Prothrombin Complex Concentrate: A Phase 3b/4 Trial in Adults with Hemophilia A with Inhibitors

Authors: Zülfikar, Bülent, Mahlangu, Johnny, Nekkal, Salim Mohamed, Ross, Cecil, Uaprasert, Noppacharn, Windyga, Jerzy, Ettingshausen, Carmen Escuriola, Ploder, Bettina, Lelli, Aurelia, Gazda, Hanna T.

Source: TH Open; July 2024, Vol. 8 Issue: 3 pe273-e282, 10p