Plasma myo-inositol elevation in heart failure: clinical implications and prognostic significance. Results from the BElgian and CAnadian MEtabolomics in HFpEF (BECAME-HF) research project

Authors: Pouleur, Anne-Catherine, Menghoum, Nassiba, Cumps, Julien, Marino, Alice, Badii, Maria, Lejeune, Sibille, Legault, Julie Thompson, Boucher, Gabrielle, Gruson, Damien, Roy, Clotilde, Battault, Sylvain, Mahrouche, Louiza, Pedneault-Gagnon, Valérie, Charpentier, Daniel, Furtos, Alexandra, Hussin, Julie, Rhainds, David, Tardif, Jean-Claude, Bertrand, Luc, Rosiers, Christine Des, Horman, Sandrine, Beauloye, Christophe

Source: In eBioMedicine September 2024 107

Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results

Authors: Baron, Cantin ^{1, 2}, Cherkaoui, Sarah ^{2, 3, 4}, Therrien-Laperriere, Sandra ², Ilboudo, Yann ^{1, 2}, Poujol, Raphaël ², Mehanna, Pamela ², Garrett, Melanie E. ⁵, Telen, Marilyn J. ⁶, Ashley-Koch, Allison E. ⁵, Bartolucci, Pablo ^{7, 8}, Rioux, John D. ^{1, 2, 9}, Lettre, Guillaume ^{2, 9}, Rosiers, Christine Des ^{1, 2, 10}, Ruiz, Matthieu ^{2, 10}, Hussin, Julie G. ^{2, 9, 11, ∗}

Source: In iScience 15 December 2023 26(12)

Branched chain amino acids selectively promote cardiac growth at the end of the awake period

Authors: Latimer, Mary N., Sonkar, Ravi, Mia, Sobuj, Frayne, Isabelle Robillard, Carter, Karen J., Johnson, Christopher A., Rana, Samir, Xie, Min, Rowe, Glenn C., Wende, Adam R., Prabhu, Sumanth D., Frank, Stuart J., Rosiers, Christine Des, Chatham, John C., Young, Martin E.

Source: In Journal of Molecular and Cellular Cardiology August 2021 157:31-44

EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors.

Authors: Lamantia, Valérie, Bissonnette, Simon, Beaudry, Myriam, Cyr, Yannick, Rosiers, Christine Des, Baass, Alexis, Faraj, May

Source: Scientific Reports; 11/7/2024, Vol. 14 Issue 1, p1-16, 16p

Subject Terms: WHITE adipose tissue, OMEGA-3 fatty acids, TYPE 2 diabetes, DOCOSAHEXAENOIC acid, EICOSAPENTAENOIC acid, CHOLESTERYL ester transfer protein

Association between fat-soluble nutrient status and auditory and visual related potentials in newly diagnosed non-screened infants with cystic fibrosis: A case-control study

Authors: Léveillé, Pauline, Knoth, Inga-Sophia, Denis, Marie-Hélène, Morin, Geneviève, Barlaam, Fanny, Nyalendo, Carine, Daneault, Caroline, Marcotte, Jacques-Edouard, Rosiers, Christine Des, Ferland, Guylaine, Lippé, Sarah, Mailhot, Geneviève

Source: In Prostaglandins, Leukotrienes and Essential Fatty Acids November 2019 150:21-30

The Association of Polyunsaturated Fatty Acid δ-5-Desaturase Activity with Risk Factors for Type 2 Diabetes Is Dependent on Plasma ApoB-Lipoproteins in Overweight and Obese Adults

Authors: Lamantia, Valérie, Bissonnette, Simon, Provost, Viviane, Devaux, Marie, Cyr, Yannick, Daneault, Caroline, Rosiers, Christine Des, Faraj, May ^*

Source: In The Journal of Nutrition January 2019 149(1):57-67

Phenomapping Of Patients With HFpEF Using Unsupervised Learning Analyses

Authors: Pop, Cristina T, Hussin, Julie, Rosiers, Christine Des, Bouabdallaoui, Nadia

Source: Journal of cardiac failure. 29(4):665-666

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188030025.0x000001&indx=1&recIds=ETOCvdc_100188030025.0x000001

Saturated high-fat feeding independent of obesity alters hypothalamus-pituitary-adrenal axis function but not anxiety-like behaviour

Authors: Hryhorczuk, Cecile, Décarie-Spain, Léa, Sharma, Sandeep, Daneault, Caroline, Rosiers, Christine Des, Alquier, Thierry, Fulton, Stephanie

Source: In Psychoneuroendocrinology September 2017 83:142-149

Acute detachment of hexokinase II from mitochondria modestly increases oxygen consumption of the intact mouse heart

Authors: Nederlof, Rianne, Denis, Simone, Lauzier, Benjamin, Rosiers, Christine Des, Laakso, Markku, Hagen, Jacob, Argmann, Carmen, Wanders, Ronald, Houtkooper, Riekelt H., Hollmann, Markus W., Houten, Sander M., Zuurbier, Coert J.

Source: In Metabolism July 2017 72:66-74

Sa449 SERUM ANALYTE PROFILES ASSOCIATED WITH CROHN'S DISEASE AND DISEASE LOCATION

Authors: Boucher, Gabrielle, Paradis, Alexandre, Chabot-Roy, Geneviève, Coderre, Lise, Hillhouse, Erin E., Bitton, Alain, Rosiers, Christine Des, Levings, Megan K., Schumm, L. Philip, Lazarev, Mark, Brant, Steven R., Duerr, Richard H., Mcgovern, Dermot P.B., Silverberg, Mark S., Cho, Judy H., Lesage, Sylvie, Rioux, John D.

Source: Gastroenterology. 160(6):S-503-S-503

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140843468.0x000001&indx=1&recIds=ETOCvdc_100140843468.0x000001

Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.

Authors: Ying Liu, Fillebeen, Carine, Forest, Anik, Botta, Amy, Varin, Thibault V., Marette, André, Burelle, Yan, Rosiers, Christine Des, Pantopoulos, Kostas, Sweeney, Gary

Source: FASEB Journal; Dec2023, Vol. 37 Issue 12, p1-15, 15p

Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism.

Authors: Yamashita, Akihiro, Ignatenko, Olesia, Nguyen, Mai, Lambert, Raphaëlle, Watt, Kathleen, Daneault, Caroline, Robillard-Frayne, Isabelle, Topisirovic, Ivan, Rosiers, Christine Des, McBride, Heidi M.

Source: Biology Direct; 9/22/2023, Vol. 18 Issue 1, p1-18, 18p

Subject Terms: CHOLESTEROL metabolism, CELL physiology, PEROXISOMAL disorders, CELL communication, PEROXISOMES, RIBOSOMAL proteins

Serum Lipidomic Screen Identifies Key Metabolites, Pathways, and Disease Classifiers in Crohn's Disease.

Authors: Ferru-Clément, Romain, Boucher, Gabrielle, Forest, Anik, Bouchard, Bertrand, Bitton, Alain, Lesage, Sylvie, Schumm, Phil, Lazarev, Mark, Brant, Steve, Duerr, Richard H, McGovern, Dermot P B, Silverberg, Mark, Cho, Judy H, Consortium, NIDDK IBD Genetics, Ananthakrishnan, Ashwin, Xavier, Ramnik J, Rioux, John D, Rosiers, Christine Des

Source: Inflammatory Bowel Diseases; Jul2023, Vol. 29 Issue 7, p1024-1037, 14p

The platelet lipidome is critically altered during septic shock

Authors: de Cartier, Emma, Dechamps, Mélanie, Robaux, Valentine, Rosiers, Christine Des, Forest, Anik, Bertrand, Luc, Ambroise, Jerome, Beauloye, Christophe, Horman, Sandrine

Source: In Archives of Cardiovascular Diseases June-July 2024 117(6-7) Supplement:S165-S165

Probing pyruvate metabolism in normal and mutant fibroblast cell lines using 13C-labeled mass isotopomer analysis and mass spectrometry

Authors: Riazi, Roya, Khairallah, Maya, Cameron, Jessie M., Pencharz, Paul B., Rosiers, Christine Des, Robinson, Brian H.

Source: In Molecular Genetics and Metabolism 2009 98(4):349-355

Differential distribution of 4-hydroxynonenal adducts to sulfur and nitrogen residues in blood proteins as revealed using Raney nickel and gas chromatography–mass spectrometry

Authors: Lesgards, Jean-François, Frayne, Isabelle Robillard, Comte, Blandine, Busseuil, David, Rhéaume, Éric, Tardif, Jean-Claude, Rosiers, Christine Des ^⁎

Source: In Free Radical Biology and Medicine 2009 47(10):1375-1385

Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation.

Authors: Hata, Masayuki^1,2, Andriessen, Elisabeth M. M. A.³, Hata, Maki¹, Diaz-Marin, Roberto², Fournier, Frédérik², Crespo-Garcia, Sergio^1,2, Blot, Guillaume^1,2, Juneau, Rachel¹, Pilon, Frédérique¹, Dejda, Agnieszka¹, Guber, Vera¹, Heckel, Emilie⁴, Daneault, Caroline⁵, Calderon, Virginie⁶, Rosiers, Christine Des⁵, Melichar, Heather J.⁷, Langmann, Thomas⁸, Joyal, Jean-Sebastien⁴, Wilson, Ariel M.¹, Sapieha, Przemyslaw^1,2, mike.sapieha@umontreal.ca

Source: Science; 1/6/2023, Vol. 379 Issue 6627, p45-62, 18p, 6 Color Photographs

Serum Analyte Profiles Associated With Crohn's Disease and Disease Location.

Authors: Boucher, Gabrielle, Paradis, Alexandre, Chabot-Roy, Geneviève, Coderre, Lise, Hillhouse, Erin E, Bitton, Alain, Rosiers, Christine Des, Levings, Megan K, Schumm, L Philip, Lazarev, Mark, Brant, Steve R, Duerr, Richard, McGovern, Dermot, Silverberg, Mark S, Cho, Judy, Lesage, Sylvie, Rioux, John D, Consortium, iGenoMed, Consortium, NIDDK IBD Genetics

Source: Inflammatory Bowel Diseases; Jan2022, Vol. 28 Issue 1, p9-20, 12p

Functional screen of inflammatory bowel disease genes reveals key epithelial functions.

Authors: Ntunzwenimana, Jessy Carol, Boucher, Gabrielle, Paquette, Jean, Gosselin, Hugues, Alikashani, Azadeh, Morin, Nicolas, Beauchamp, Claudine, Thauvette, Louise, Rivard, Marie-Ève, Dupuis, Frédérique, Deschênes, Sonia, Foisy, Sylvain, Latour, Frédéric, Lavallée, Geneviève, Daly, Mark J., Xavier, Ramnik J., the iGenoMed Consortium, Bitton, Alain, Charron, Guy, Rosiers, Christine Des

Source: Genome Medicine; 11/11/2021, Vol. 13 Issue 1, p1-21, 21p

Subject Terms: INFLAMMATORY bowel diseases, INTESTINAL mucosa, LOCUS (Genetics), IMMUNOGLOBULIN receptors, GENES, PHENOTYPES, TYPE I interferons

Reducing 14-3-3ζ expression influences adipocyte maturity and impairs function.

Authors: Oppong, Abel K., Diallo, Kadidia, Frayne, Isabelle Robillard, Rosiers, Christine Des, Lim, Gareth E.

Source: American Journal of Physiology: Endocrinology & Metabolism; Jul2020, Vol. 319 Issue 1, pE117-E132, 16p, 3 Charts, 9 Graphs