Specific gut pathobionts escape antibody coating and are enriched during flares in patients with severe Crohn’s disease.

Authors: Eriksen, Carsten, Danneskiold-Samsøe, Niels Banhos, Moll, Janne Marie, Myers, Pernille Neve, Bondegaard, Pi W., Vejrum, Simone, Hansen, Tine Brodka, Rosholm, Lisbeth Buus, Rausch, Philipp, Allin, Kristine Højgaard, Jess, Tine, Kristiansen, Karsten, Penders, John, Jonkers, Daisy, Brix, Susanne

Source: Gut; Mar2024, Vol. 73 Issue 3, p448-458, 11p

Subject Terms: CROHN'S disease, SHIGELLOSIS, SURFACE coatings, INFLAMMATORY bowel diseases, IRRITABLE colon, NEGATIVE binomial distribution

IgG and IgM cooperate in coating of intestinal bacteria in IgA deficiency.

Authors: Eriksen, Carsten, Moll, Janne Marie, Myers, Pernille Neve, Pinto, Ana Rosa Almeida, Danneskiold-Samsøe, Niels Banhos, Dehli, Rasmus Ibsen, Rosholm, Lisbeth Buus, Dalgaard, Marlene Danner, Penders, John, Jonkers, Daisy MAE, Pan-Hammarström, Qiang, Hammarström, Lennart, Kristiansen, Karsten, Brix, Susanne

Source: Nature Communications; 12/8/2023, Vol. 14 Issue 1, p1-12, 12p

Subject Terms: IMMUNOGLOBULIN M, IMMUNOGLOBULIN A, INFLAMMATORY bowel diseases, IMMUNOGLOBULINS, SURFACE coatings, INTESTINES

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Mycobacterium tuberculosis promotes Th17 expansion via regulation of human dendritic cells toward a high CD14 and low IL-12p70 phenotype that reprograms upon exogenous IFN-γ.

Authors: Søndergaard, Jonas Nørskov, Laursen, Janne Marie, Rosholm, Lisbeth Buus, Brix, Susanne

Source: International Immunology; Dec2014, Vol. 26 Issue 12, p705-716, 12p

Subject Terms: MYCOBACTERIUM tuberculosis, T helper cells, CELLULAR control mechanisms, DENDRITIC cells, CD14 antigen, INTERLEUKIN-12, INTERLEUKIN-18, IMMUNOREGULATION

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