Potential and limitations of patient-specific inkjet printing on orodispersible films: A critical and practical look at innovation barriers for pharmaceutical applications

Authors: Brokmann, Friederike, Menzdorf, Ida, Daab, Anna, Rosenbaum, Christoph ^⁎

Source: In Journal of Drug Delivery Science and Technology April 2025 106

Prolongation of the gastric residence time of caffeine after administration in fed state: Comparison of effervescent granules with an extended release tablet

Authors: Foja, Constantin, Senekowitsch, Stefan, Winter, Fabian, Grimm, Michael, Rosenbaum, Christoph, Koziolek, Mirko, Feldmüller, Maximilian, Kromrey, Marie-Luise, Scheuch, Eberhard, Tzvetkov, Mladen V., Weitschies, Werner, Schick, Philipp

Source: In European Journal of Pharmaceutics and Biopharmaceutics June 2024 199

Scalability of API-Loaded Multifilament Yarn Production by Hot-Melt Extrusion and Evaluation of Fiber-Based Dosage Forms.

Authors: Rosenbaum, Christoph¹ (AUTHOR) christoph.rosenbaum@uni-greifswald.de, Gerds, Naemi¹ (AUTHOR), Hack, Liliane¹ (AUTHOR), Weitschies, Werner¹ (AUTHOR)

Source: Pharmaceutics. Aug2024, Vol. 16 Issue 8, p1103. 14p.

Subject Terms: *TARGETED drug delivery, *MELT spinning, *EXTRUSION process, *SURFACE roughness, *POLYVINYL alcohol

Establishment of a Dissolution Test System for the Biorelevant Characterization of Esophageal Applied Dosage Forms

Authors: Rosenbaum, Christoph Maria, Brokmann, Friederike, Krause, Julius, Weitschies, Werner

Source: Journal of pharmaceutical sciences. 111(1):62-68

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151214965.0x000001&indx=1&recIds=ETOCvdc_100151214965.0x000001

The challenges of drug delivery to the esophagus and how to overcome them

Authors: Krause, Julius, Brokmann, Friederike, Rosenbaum, Christoph, Weitschies, Werner

Source: Expert opinion on drug delivery. 19(2):119-131

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144961388.0x000001&indx=1&recIds=ETOCvdc_100144961388.0x000001

Development of Novel Oral Delivery Systems Using Additive Manufacturing Technologies to Overcome Biopharmaceutical Challenges for Future Targeted Drug Delivery.

Authors: Cirilli, Micol, Krause, Julius, Gazzaniga, Andrea, Weitschies, Werner, Cerea, Matteo, Rosenbaum, Christoph

Source: Pharmaceutics; Jan2025, Vol. 17 Issue 1, p29, 13p

Subject Terms: TARGETED drug delivery, DRUG delivery systems, CONTROLLED release drugs, DRUG absorption, SMALL intestine

The light collection non-uniformity of strongly tapered PWO crystals and its impact on the energy resolution of the PANDA electromagnetic calorimeter in the energy region below 1 GeV

Authors: Diehl, Stefan, Brinkmann, Kai-Thomas, Drexler, Peter, Dormenev, Valery, Novotny, Rainer W., Rosenbaum, Christoph, Zaunick, Hans-Georg

Source: 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD), 2016. :1-2 Oct, 2016

Relation: 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)

The EsoCap-system – An innovative platform to drug targeting in the esophagus

Authors: Krause, Julius, Rosenbaum, Christoph, Grimm, Michael, Rump, Adrian, Keßler, Rebecca, Hosten, Norbert, Weitschies, Werner

Source: In Journal of Controlled Release 10 November 2020 327:1-7

Determination of Mucoadhesion of Polyvinyl Alcohol Films to Human Intestinal Tissue.

Authors: Müller, Laura¹ (AUTHOR), Rosenbaum, Christoph¹ (AUTHOR), Rump, Adrian¹ (AUTHOR), Grimm, Michael¹ (AUTHOR), Klammt, Friederike¹ (AUTHOR), Kleinwort, Annabel² (AUTHOR), Busemann, Alexandra² (AUTHOR), Weitschies, Werner¹ (AUTHOR) werner.weitschies@uni-greifswald.de

Source: Pharmaceutics. Jun2023, Vol. 15 Issue 6, p1740. 14p.

Subject Terms: *POLYVINYL alcohol, *FROZEN semen, *DRUG delivery systems, *DRUG absorption, *INTESTINAL mucosa, *HUMAN experimentation

Stability of Free and Liposomal Encapsulated RNA on a Mucoadhesive PVA Polymer for Esophageal RNA Drug Targeting Using the EsoCap System.

Authors: Weide, Aileen, Brokmann, Friederike, Appel, Bettina, Rosenbaum, Christoph, Krause, Julius, Janke, Una, Delcea, Mihaela, Weitschies, Werner, Müller, Sabine

Source: Advanced Therapeutics; Aug2024, Vol. 7 Issue 8, p1-9, 9p

Modification of the Biorelevant Release Testing of Esophageal Applied Mucoadhesive Films and Development of Formulation Strategies to Increase the Mucosal Contact Time.

Authors: Brokmann, Friederike, Simonek, Paul, Rosenbaum, Christoph

Source: Pharmaceutics; Aug2024, Vol. 16 Issue 8, p1021, 13p

Subject Terms: ESOPHAGUS diseases, TARGETED drug delivery, TEST systems, DISEASE prevalence, ESOPHAGUS

Characterization of an In Vitro/Ex Vivo Mucoadhesiveness Measurement Method of PVA Films.

Authors: Müller, Laura¹ (AUTHOR), Rosenbaum, Christoph¹ (AUTHOR), Krause, Julius¹ (AUTHOR), Weitschies, Werner¹ (AUTHOR) werner.weitschies@uni-greifswald.de

Source: Polymers (20734360). Dec2022, Vol. 14 Issue 23, p5146. 17p.

Subject Terms: *DRUG delivery systems, *POLYVINYL alcohol, *TENSILE tests, *DRUG dosage, *TEST systems, *TISSUES

Distribution of fluorescein sodium and triamcinolone acetonide in the simulated liquefied and vitrectomized Vitreous Model with simulated eye movements

Authors: Stein, Sandra, Bogdahn, Malte, Rosenbaum, Christoph, Weitschies, Werner, Seidlitz, Anne

Source: In European Journal of Pharmaceutical Sciences 15 November 2017 109:233-243

Measurement and optimization of the light collection uniformity in strongly tapered PWO crystals of the PANDA detector

Authors: Diehl, Stefan, Bremer, Daniel, Brinkmann, Kai-Thomas, Dormenev, Valery, Eissner, Tobias, Novotny, Rainer W., Rosenbaum, Christoph, Zaunick, Hans-Georg

Source: In Nuclear Inst. and Methods in Physics Research, A 11 June 2017 857:1-6

Development of a Hot-Melt-Extrusion-Based Spinning Process to Produce Pharmaceutical Fibers and Yarns.

Authors: Rosenbaum, Christoph¹ (AUTHOR) christoph.rosenbaum@uni-greifswald.de, Großmann, Linus¹ (AUTHOR) linus.grossmann@uni-greifswald.de, Neumann, Ellen¹ (AUTHOR) ellen.neumann@stud.uni-greifswald.de, Jungfleisch, Petra² (AUTHOR) p.jungfleisch@mybiotech.de, Türeli, Emre² (AUTHOR) e.tuereli@mybiotech.de, Weitschies, Werner¹ (AUTHOR) werner.weitschies@uni-greifswald.de

Source: Pharmaceutics. Jun2022, Vol. 14 Issue 6, p1229-N.PAG. 12p.

Subject Terms: *MELT spinning, *EXTRUSION process, *YARN, *RAPID prototyping, *FIBERS, *THREE-dimensional printing, *TENSILE strength

Geographic Terms: GERMANY

Development of Test Programs for the Biorelevant Characterization of Esophageal-Applied Dosage Forms.

Authors: Brokmann, Friederike, Feindt, Franziska, Weitschies, Werner, Rosenbaum, Christoph

Source: Polymers (20734360); Aug2023, Vol. 15 Issue 16, p3430, 12p

Subject Terms: LIQUID films, RF values (Chromatography), MUCOUS membranes, PERISTALSIS, DOSAGE forms of drugs, THERAPEUTICS, SOLID dosage forms

Optimization of the Front-End electronics of the PANDA Barrel EMC

Authors: Rosenbaum, Christoph, Rose tree, Christoph

Availability: http://data.europeana.eu/aggregation/europeana/2048441/item_NW4YG6DDFG6J6SSMDWDQWE2UC5CS2G5F

Intragastric Carbon Dioxide Release Prolongs the Gastric Residence Time of Postprandially Administered Caffeine.

Authors: Senekowitsch, Stefan, Foja, Constantin, Wildgrube, Toni, Schick, Philipp, Rosenbaum, Christoph, Krause, Julius, Brokmann, Friederike, Kromrey, Marie-Luise, Engeli, Stefan, Weitschies, Werner, Grimm, Michael

Source: Pharmaceutics; Mar2023, Vol. 15 Issue 3, p1012, 19p

Subject Terms: CARBON dioxide, GASTROINTESTINAL motility, CAFFEINE, DRUG absorption, GASTRIC emptying, DWELLINGS

Functionality and Acceptance of the EsoCap System—A Novel Film-Based Drug Delivery Technology: Results of an In Vivo Study.

Authors: Rosenbaum, Christoph¹ (AUTHOR) christoph.rosenbaum@uni-greifswald.de, Grimm, Michael¹ (AUTHOR) michael.grimm@uni-greifswald.de, Krause, Julius¹ (AUTHOR) julius.krause@uni-greifswald.de, Rump, Adrian¹ (AUTHOR) adrian.rump@uni-greifswald.de, Kessler, Rebecca² (AUTHOR) rebecca.kessler@uni-greifswald.de, Hosten, Norbert² (AUTHOR) hosten@uni-greifswald.de, Weitschies, Werner¹ (AUTHOR) werner.weitschies@uni-greifswald.de

Source: Pharmaceutics. Jun2021, Vol. 13 Issue 6, p828. 1p.

Subject Terms: *DRUG delivery systems, *DRUG delivery devices, *EOSINOPHILIC esophagitis, *ESOPHAGUS diseases, *POLYMER films, *ESOPHAGUS

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