Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

Authors: Qi Zhang, Bridget Riley-Gillis, Lina Han, Yanan Jia, Alessia Lodi, Haijiao Zhang, Saravanan Ganesan, Rongqing Pan, Sergej N. Konoplev, Shannon R. Sweeney, Jeremy A. Ryan, Yulia Jitkova, Kenneth Dunner, Shaun E. Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen Kurtz, Vivian R. Ruvolo, Helen Ma, Connie C. Weng, Cassandra L. Ramage, Natalia Baran, Ce Shi, Tianyu Cai, Richard Eric Davis, Venkata L. Battula, Yingchang Mi, Jing Wang, Courtney D. DiNardo, Michael Andreeff, Jeffery W. Tyner, Aaron Schimmer, Anthony Letai, Rose Ann Padua, Carlos E. Bueso-Ramos, Stefano Tiziani, Joel Leverson, Relja Popovic, Marina Konopleva

Source: Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-13 (2022)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/d7945566353e4cff944fa98c53fc192d

Correction: Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

Authors: Qi Zhang, Bridget Riley-Gillis, Lina Han, Yannan Jia, Alessia Lodi, Haijiao Zhang, Saravanan Ganesan, Rongqing Pan, Sergej N. Konoplev, Shannon R. Sweeney, Jeremy A. Ryan, Yulia Jitkova, Kenneth Dunner, Shaun E. Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen Kurtz, Vivian R. Ruvolo, Helen Ma, Connie C. Weng, Cassandra L. Ramage, Natalia Baran, Ce Shi, Tianyu Cai, Richard Eric Davis, Venkata L. Battula, Yingchang Mi, Jing Wang, Courtney D. DiNardo, Michael Andreeff, Jeffery W. Tyner, Aaron Schimmer, Anthony Letai, Rose Ann Padua, Carlos E. Bueso-Ramos, Stefano Tiziani, Joel Leverson, Relja Popovic, Marina Konopleva

Source: Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-1 (2022)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/0bea0028687644349367928f6f176be8

Arsenic Trioxide Enhances the NK Cell Cytotoxicity Against Acute Promyelocytic Leukemia While Simultaneously Inhibiting Its Bio-Genesis

Authors: Ansu Abu Alex, Saravanan Ganesan, Hamenth Kumar Palani, Nithya Balasundaram, Sachin David, Kavitha M. Lakshmi, Uday P. Kulkarni, P. N. Nisham, Anu Korula, Anup J. Devasia, Nancy Beryl Janet, Aby Abraham, Alok Srivastava, Biju George, Rose Ann Padua, Christine Chomienne, Poonkuzhali Balasubramanian, Vikram Mathews

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: natural killer cells, arsenic trioxide, immune response, acute promyelocytic leukemia, APL mouse model, NK cellular therapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.01357/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ebaf9823b20b4e3e92261a9c940f0f4c

GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

Authors: Laura Guerenne, Stéphanie Beurlet, Mohamed Said, Petra Gorombei, Carole Le Pogam, Fabien Guidez, Pierre de la Grange, Nader Omidvar, Valérie Vanneaux, Ken Mills, Ghulam J Mufti, Laure Sarda-Mantel, Maria Elena Noguera, Marika Pla, Pierre Fenaux, Rose Ann Padua, Christine Chomienne, Patricia Krief

Source: Journal of Hematology & Oncology, Vol 9, Iss 1, Pp 1-20 (2016)

Subject Terms: Myelodysplastic syndrome, Mice models, Gene expression profile, MDS, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13045-016-0235-8; https://doaj.org/toc/1756-8722

Access URL: https://doaj.org/article/5f34a28afe924b7bb0e3dc96b14f7206

Cellular and gene therapy

Authors: Rose Ann Padua, (Coordinating Author)

Source: HemaSphere, Vol 3, p 27 (2019)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000265; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/0b785a0771114e04a981424d5435b3c8

Comparison of newly diagnosed and relapsed patients with acute promyelocytic leukemia treated with arsenic trioxide: insight into mechanisms of resistance.

Authors: Ezhilarasi Chendamarai, Saravanan Ganesan, Ansu Abu Alex, Vandana Kamath, Sukesh C Nair, Arun Jose Nellickal, Nancy Beryl Janet, Vivi Srivastava, Kavitha M Lakshmi, Auro Viswabandya, Aby Abraham, Mohammed Aiyaz, Nandita Mullapudi, Raja Mugasimangalam, Rose Ann Padua, Christine Chomienne, Mammen Chandy, Alok Srivastava, Biju George, Poonkuzhali Balasubramanian, Vikram Mathews

Source: PLoS ONE, Vol 10, Iss 3, p e0121912 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4378855?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/df7684acf6474b0e8b346f8d42ae963e

Engineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?

Authors: Stephanie Beurlet, Christine Chomienne, Rose Ann Padua

Source: Haematologica, Vol 98, Iss 1 (2013)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/6520; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/1d5e5014820d4c89bb2e2166e1812037