Development of methodology to support molecular endotype discovery from synovial fluid of individuals with knee osteoarthritis: The STEpUP OA consortium

Authors: Yun Deng, Thomas A. Perry, Philippa Hulley, Rose A. Maciewicz, Joanna Mitchelmore, Darryl Perry, Staffan Larsson, Sophie Brachat, André Struglics, C. Thomas Appleton, Stefan Kluzek, Nigel K. Arden, David Felson, Brian Marsden, Brian D. M. Tom, Laura Bondi, Mohit Kapoor, Vicky Batchelor, Jennifer Mackay-Alderson, Vinod Kumar, L. Stefan Lohmander, Tim J. Welting, David A. Walsh, Ana M. Valdes, Tonia L. Vincent, Fiona E. Watt, Luke Jostins-Dean

Source: PLoS ONE, Vol 19, Iss 11 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573211/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e107354c921040809fc658e38a577604

Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts

Authors: John J. Cole, Bekir A. Faydaci, David McGuinness, Robin Shaw, Rose A. Maciewicz, Neil A. Robertson, Carl S. Goodyear

Source: BMC Bioinformatics, Vol 22, Iss 1, Pp 1-21 (2021)

Subject Terms: Bulk, RNA-seq, Pipeline, Automation, Visualisation, Exploration, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/9bca106272ef4240bc9afd063a856c67

Large‐scale plasma proteomics can reveal distinct endotypes in chronic obstructive pulmonary disease and severe asthma

Authors: Masaru Suzuki, John J. Cole, Satoshi Konno, Hironi Makita, Hiroki Kimura, Masaharu Nishimura, Rose A. Maciewicz

Source: Clinical and Translational Allergy, Vol 11, Iss 10, Pp n/a-n/a (2021)

Subject Terms: COPD, エンドタイプ, エクソソーム, プロテオミクス, 重症喘息, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7022

Access URL: https://doaj.org/article/350d910b3ad24cb48ea7afa0a21f259d

MEK inhibition drives anti-viral defence in RV but not RSV challenged human airway epithelial cells through AKT/p70S6K/4E-BP1 signalling

Authors: Engin Baturcam, Stefan Vollmer, Holger Schlüter, Rose A. Maciewicz, Nisha Kurian, Outi Vaarala, Stephan Ludwig, Danen Mootoosamy Cunoosamy

Source: Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-19 (2019)

Subject Terms: Human rhinovirus, Respiratory syncytial virus, Innate immune response, Interferon-β, Interferon stimulated genes, Dual specificity mitogen-activated protein kinase kinase (MEK) pathway, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12964-019-0378-7; https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/37834a1f40794b25b512aab2c43f11ac

Development of methodology to support molecular endotype discovery from synovial fluid of individuals with knee osteoarthritis: The STEpUP OA consortium.

Authors: Yun Deng, Thomas A Perry, Philippa Hulley, Rose A Maciewicz, Joanna Mitchelmore, Darryl Perry, Staffan Larsson, Sophie Brachat, André Struglics, C Thomas Appleton, Stefan Kluzek, Nigel K Arden, David Felson, Brian Marsden, Brian D M Tom, Laura Bondi, Mohit Kapoor, Vicky Batchelor, Jennifer Mackay-Alderson, Vinod Kumar, L Stefan Lohmander, Tim J Welting, David A Walsh, Ana M Valdes, STEpUP OA Consortium, Tonia L Vincent, Fiona E Watt, Luke Jostins-Dean

Source: PLoS ONE, Vol 19, Iss 11, p e0309677 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1a7b992e033f487392bdc5e67be7b7f1

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.

Authors: Martha C Castaño-Betancourt, Dan S Evans, Yolande F M Ramos, Cindy G Boer, Sarah Metrustry, Youfang Liu, Wouter den Hollander, Jeroen van Rooij, Virginia B Kraus, Michelle S Yau, Braxton D Mitchell, Kenneth Muir, Albert Hofman, Michael Doherty, Sally Doherty, Weiya Zhang, Robert Kraaij, Fernando Rivadeneira, Elizabeth Barrett-Connor, Rose A Maciewicz, Nigel Arden, Rob G H H Nelissen, Margreet Kloppenburg, Joanne M Jordan, Michael C Nevitt, Eline P Slagboom, Deborah J Hart, Floris Lafeber, Unnur Styrkarsdottir, Eleftheria Zeggini, Evangelos Evangelou, Tim D Spector, Andre G Uitterlinden, Nancy E Lane, Ingrid Meulenbelt, Ana M Valdes, Joyce B J van Meurs

Source: PLoS Genetics, Vol 12, Iss 10, p e1006260 (2016)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006260&type=printable; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/346cded1a0c64f81b7b42090748bb1f4

Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations.

Authors: Ana M Valdes, Unnur Styrkarsdottir, Michael Doherty, David L Morris, Massimo Mangino, Agu Tamm, Sally A Doherty, Kalle Kisand, Irina Kerna, Ann Tamm, Margaret Wheeler, Rose A Maciewicz, Weiya Zhang, Kenneth R Muir, Elaine M Dennison, Deborah J Hart, Sarah Metrustry, Ingileif Jonsdottir, Gudbjorn F Jonsson, Helgi Jonsson, Thorvaldur Ingvarsson, Cyrus Cooper, Timothy J Vyse, Tim D Spector, Kari Stefansson, Nigel K Arden

Source: PLoS ONE, Vol 6, Iss 8, p e23371 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3154440?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e96f0801c8564122b6eb09219f2f8b71