Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer

Authors: Florian Malchers, Lucia Nogova, Martijn H.A. van Attekum, Lukas Maas, Johannes Brägelmann, Christoph Bartenhagen, Luc Girard, Graziella Bosco, Ilona Dahmen, Sebastian Michels, Clare E. Weeden, Andreas H. Scheel, Lydia Meder, Kristina Golfmann, Philipp Schuldt, Janna Siemanowski, Jan Rehker, Sabine Merkelbach-Bruse, Roopika Menon, Oliver Gautschi, Johannes M. Heuckmann, Elisabeth Brambilla, Marie-Liesse Asselin-Labat, Thorsten Persigehl, John D. Minna, Henning Walczak, Roland T. Ullrich, Matthias Fischer, Hans Christian Reinhardt, Jürgen Wolf, Reinhard Büttner, Martin Peifer, Julie George, Roman K. Thomas

Source: The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)

Subject Terms: Genetics, Oncology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/ef6247e9f6b84dbca5a0844486ed3d80

Cell-free tumor DNA, CA125 and HE4 for the objective assessment of tumor burden in patients with advanced high-grade serous ovarian cancer.

Authors: Florian Heitz, Sotirios Lakis, Philipp Harter, Sebastian Heikaus, Jalid Sehouli, Jatin Talwar, Roopika Menon, Beyhan Ataseven, Miriam Bertrand, Stephanie Schneider, Erika Mariotti, Mareike Bommert, Judith N Müller, Sonia Prader, Frauke Leenders, Alexandra Hengsbach, Christian Gloeckner, Elena Ioana Braicu, Lukas C Heukamp, Andreas du Bois, Johannes M Heuckmann

Source: PLoS ONE, Vol 17, Iss 2, p e0262770 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e2bb896377e24b0ba18e2a7ddeeda5de

Clinical Impact of Immune Checkpoint Inhibitor (ICI) Response, DNA Damage Repair (DDR) Gene Mutations and Immune-Cell Infiltration in Metastatic Melanoma Subtypes

Authors: Charlotte Andrieu, Niamh McNamee, Anne-Marie Larkin, Alanna Maguire, Roopika Menon, Judith Mueller-Eisert, Noel Horgan, Susan Kennedy, Giuseppe Gullo, John Crown, Naomi Walsh

Source: Medical Sciences, Vol 10, Iss 2, p 26 (2022)

Subject Terms: cutaneous melanoma, uveal melanoma, head and neck melanoma, mucosal melanoma, acral lentiginous melanoma, immunotherapy, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3271/10/2/26; https://doaj.org/toc/2076-3271

Access URL: https://doaj.org/article/3453e78c93ba4a72b2f1c7a5332b0f8d

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

Authors: Julie George, Vonn Walter, Martin Peifer, Ludmil B. Alexandrov, Danila Seidel, Frauke Leenders, Lukas Maas, Christian Müller, Ilona Dahmen, Tiffany M. Delhomme, Maude Ardin, Noemie Leblay, Graham Byrnes, Ruping Sun, Aurélien De Reynies, Anne McLeer-Florin, Graziella Bosco, Florian Malchers, Roopika Menon, Janine Altmüller, Christian Becker, Peter Nürnberg, Viktor Achter, Ulrich Lang, Peter M. Schneider, Magdalena Bogus, Matthew G. Soloway, Matthew D. Wilkerson, Yupeng Cun, James D. McKay, Denis Moro-Sibilot, Christian G. Brambilla, Sylvie Lantuejoul, Nicolas Lemaitre, Alex Soltermann, Walter Weder, Verena Tischler, Odd Terje Brustugun, Marius Lund-Iversen, Åslaug Helland, Steinar Solberg, Sascha Ansén, Gavin Wright, Benjamin Solomon, Luca Roz, Ugo Pastorino, Iver Petersen, Joachim H. Clement, Jörg Sänger, Jürgen Wolf, Martin Vingron, Thomas Zander, Sven Perner, William D. Travis, Stefan A. Haas, Magali Olivier, Matthieu Foll, Reinhard Büttner, David Neil Hayes, Elisabeth Brambilla, Lynnette Fernandez-Cuesta, Roman K. Thomas

Source: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0b984304ba014836a34f2b6d1a57b335

ALK G1269A mutation as a potential mechanism of acquired resistance to crizotinib in an ALK-rearranged inflammatory myofibroblastic tumor

Authors: Sebastian Y. F. Michels, Andreas H. Scheel, Thomas Wündisch, Johannes M. Heuckmann, Roopika Menon, Michael Puesken, Carsten Kobe, Helen Pasternack, Carina Heydt, Matthias Scheffler, Rieke Fischer, Anne M. Schultheis, Sabine Merkelbach-Bruse, Lukas Heukamp, Reinhard Büttner, Jürgen Wolf

Source: npj Precision Oncology, Vol 1, Iss 1, Pp 1-4 (2017)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/33a80232e38044a3a05d9a9bbd74b52a

Characterization of FGFR1 Locus in sqNSCLC Reveals a Broad and Heterogeneous Amplicon.

Authors: Claire Rooney, Catherine Geh, Victoria Williams, Johannes M Heuckmann, Roopika Menon, Petra Schneider, Katherine Al-Kadhimi, Michael Dymond, Neil R Smith, Dawn Baker, Tim French, Paul D Smith, Elizabeth A Harrington, J Carl Barrett, Elaine Kilgour

Source: PLoS ONE, Vol 11, Iss 2, p e0149628 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4764357?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/2b46afdd7fe449e0b477e84cd24b5622