Safety, immunogenicity, and efficacy of a modified COVID-19 mRNA vaccine, SW-BIC-213, in healthy people aged 18 years and above: a phase 3 double-blinded, randomized, parallel controlled clinical trial in Lao PDR (Laos)Research in context

Authors: Yi Fang, Jing-Xin Li, Davone Duangdany, Yang Li, Xi-Lin Guo, Chanthala Phamisith, Bo Yu, Ming-Yun Shen, Bin Luo, Yu-Zhu Wang, Si-Jun Liu, Fan-Fan Zhao, Cong-Cong Xu, Xu-Hui Qiu, Rong Yan, Yu-Zhou Gui, Rong-Juan Pei, Jie Wang, Haifa Shen, Wu-Xiang Guan, Hang-Wen Li, Mayfong Mayxay

Source: EClinicalMedicine, Vol 67, Iss , Pp 102372- (2024)

Subject Terms: SARS-CoV-2, COVID-19, mRNA vaccine, Lipopolyplex (LPP), Heterologous boosting, Phase 3 trial, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537023005497; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/b49863887c81437fa479a9b75dda6a56

Efficacy of heterologous boosting against SARS-CoV-2 using a recombinant interferon-armed fusion protein vaccine (V-01): a randomized, double-blind and placebo-controlled phase III trial

Authors: Xuan-Yi Wang, Syed Faisal Mahmood, Fang Jin, Wee Kooi Cheah, Muhammad Ahmad, Mian Amjad Sohail, Waheed Ahmad, Vijaya K. Suppan, Muneeba Ahsan Sayeed, Shobha Luxmi, Aik-Howe Teo, Li Yuan Lee, Yang-Yang Qi, Rong-Juan Pei, Wei Deng, Zhong-Hui Xu, Jia-Ming Yang, Yan Zhang, Wu-Xiang Guan, Xiong Yu

Source: Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1910-1919 (2022)

Subject Terms: Efficacy, heterologous boosting, subunit vaccine, clinical trial, fusion protein, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/13f41faa0d4745e0b05e34dbacca36c9

Immunogenicity and safety of a recombinant fusion protein vaccine (V-01) against coronavirus disease 2019 in healthy adults: a randomized, double-blind, placebo-controlled, phase II trial

Authors: Ya-Jun Shu, Jian-Feng He, Rong-Juan Pei, Peng He, Zhu-Hang Huang, Shao-Min Chen, Zhi-Qiang Ou, Jing-Long Deng, Pei-Yu Zeng, Jian Zhou, Yuan-Qin Min, Fei Deng, Hua Peng, Zheng Zhang, Bo Wang, Zhong-Hui Xu, Wu-Xiang Guan, Zhong-Yu Hu, Ji-Kai Zhang, Jing Ni

Source: Chinese Medical Journal, Vol 134, Iss 16, Pp 1967-1976 (2021)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/CM9.0000000000001702; https://doaj.org/toc/0366-6999; https://doaj.org/toc/2542-5641

Access URL: https://doaj.org/article/a6c9a6de1a9a453aaf81259a81badcec

Histone deacetylase 3 promotes innate antiviral immunity through deacetylation of TBK1

Authors: Jie-lin Tang, Qi Yang, Chong-hui Xu, He Zhao, Ya-ling Liu, Can-yu Liu, Yuan Zhou, Dong-wei Gai, Rong-juan Pei, Yun Wang, Xue Hu, Bo Zhong, Yan-yi Wang, Xin-wen Chen, Ji-zheng Chen

Source: Protein & Cell, Vol 12, Iss 4, Pp 261-278 (2020)

Subject Terms: TBK1, HDAC3, deacetylation, IRF3, innate immune, Cytology, QH573-671, Animal biochemistry, QP501-801

File Description: electronic resource

Relation: https://doaj.org/toc/1674-800X; https://doaj.org/toc/1674-8018

Access URL: https://doaj.org/article/65ca7654fa64403e8c01c160cfd956e6